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Plowright Raina K RK Department of Microbiology and Immunology, Montana State University, Bozeman, MT 59717, USA Center for Infectious Disease Dynamics, Pennsylvania State University, State College, PA, USA - - 2015
Viruses that originate in bats may be the most notorious emerging zoonoses that spill over from wildlife into domestic animals and humans. Understanding how these infections filter through ecological systems to cause disease in humans is of profound importance to public health. Transmission of viruses from bats to humans requires ...
Williams Kinola J N KJ 1 Department of Medical Microbiology and Immunology, University of Alberta , Edmonton, Canada - - 2014
Abstract Members of the species Zaire ebolavirus cause severe hemorrhagic fever with up to a 90% mortality rate in humans. The VSVΔG/EBOV GP vaccine has provided 100% protection in the mouse, guinea pig, and nonhuman primate (NHP) models, and has also been utilized as a post-exposure therapeutic to protect mice, ...
Arthur Margaret M Living in - - 2014
Reddit is a source for what's new and popular on the web. Users provide all the content and decide, through voting, what is good, interesting and informative.
- - 2014
England's chief nurse has urged nurses to remain vigilant to the threat of the Ebola virus.
Melanson Vanessa R VR 1 Entomology Department, Walter Reed Army Institute of Research , Silver Spring, - - 2014
Abstract Filoviruses subvert the human immune system in part by infecting and replicating in dendritic cells (DCs). Using gene arrays, a phenotypic profile of filovirus infection in human monocyte-derived DCs was assessed. Monocytes from human donors were cultured in GM-CSF and IL-4 and were infected with Ebola virus Kikwit variant ...
Nusbaum Neil J NJ VA Central Western Massachusetts Healthcare System, Leeds, MA, 01053, USA, - - 2014
Current care for Ebola patients in resource poor countries is hampered by a lack of resources to isolate patients and their close contacts. The current Ebola epidemic offers the opportunity to harvest convalescent serum to help contain this and future outbreaks. A systemic and just process to accomplish this goal ...
Stein Zena A ZA HIV Center for Clinical and Behavioral Studies, Division of Gender, Sexuality and Health, New York State Psychiatric Institute and Columbia University, New York, NY, USA HIV Center for Clinical and Behavioral Studies, Division of Gender, Sexuality and Health, New York State Psychiatric Institute and Columbia University, New York, NY, - - 2014
Ebrahim Shah S London School of Hygiene & Tropical Medicine, London, - - 2014
Roberts Ian I Clinical Trials Unit, London School of Hygiene & Tropical Medicine, London WC1E 7HT, UK. Electronic address: - - 2014
Kimball Ann Marie AM Department of Epidemiology, University of Washington, Seattle, WA 98195, USA. Electronic address: - - 2014
Hassid Edwin J EJ California Pacific Medical Center, San Francisco, - - 2014
Bickler Stephen W SW Center for Investigations of Health and Education Disparities, University of California San Diego, 9500 Gilman Drive, #0739, La Jolla, CA, 92093-0739, USA, - - 2014
Waters Ami A Division of Hospital Medicine, University of California San Francisco, San Francisco, - - 2014
Travis Dominic A DA Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, - - 2014
Characterizing the health consequences of interactions among animals, humans, and the environment in the face of climatic change, environmental disturbance, and expanding human populations is a critical global challenge in today's world. Exchange of interdisciplinary knowledge in basic and applied sciences and medicine that includes scientists, health professionals, key sponsors, ...
Papaneri Amy A NIH/NIAID, Ft. Detrick, MD - - 2014
Using a recombinant rabies (RABV) vaccine platform, we have developed several safe and effective vaccines. Most recently, we have developed a RABV-based ebolavirus (EBOV) vaccine that is efficacious in nonhuman primates. One safety feature of this vaccine is the utilization of a live but replication-deficient RABV construct. In this construct, ...
Wolf Timo T Facharzt für Innere Medizin und Infektiologie, Universitätsklinikum Frankfurt, Medizinische Klinik II, Infektiologie, Frankfurt, - - 2014
Cox Edward E From the Center for Drug Evaluation and Research (E.C., R.T.) and the Office of the Commissioner (L.B.), Food and Drug Administration, Silver Spring, - - 2014
The worst Ebola epidemic in history is ongoing. With the number of deaths from Ebola virus disease (EVD) already in the thousands and predicted to rise to tens of thousands,(1) the situation is tragic. No treatments have yet been shown to be safe and effective in patients with EVD. Some ...
Petersen Eskild E Faculty of Medicine and Odonto-Stomatology University of Sciences, Techniques and Technology of Bamako (USTTB) of Bamako, - - 2014
De Clercq Erik E Rega Institute for Medical Research, KU Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium. Electronic address: - - 2014
Within less than a year after its epidemic started (in December 2013) in Guinea, Ebola virus (EBOV), a member of the filoviridae, has spread over a number of West-African countries (Guinea, Sierra Leone and Liberia) and gained allures that have been unprecedented except by human immunodeficiency virus (HIV). Although EBOV ...
Lauck Michael M Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA Wisconsin National Primate Research Center, Madison, Wisconsin, - - 2014
In 49 patients with known Ebolavirus (EBOV) outcomes during the ongoing outbreak in Sierra Leone, 13 were co-infected with the immunomodulatory pegivirus GB virus C (GBV-C). 53% of these GBV-C+ patients survived; in contrast, only 22% of GBV-C(-) patients survived. Both survival and GBV-C status were associated with age, with ...
Jacobs Michael M Department of Infectious Diseases, Royal Free London NHS Foundation Trust, London NW3 2QG, UK. Electronic address: - - 2014
O'Dempsey Tim T Liverpool School of Tropical Medicine, Liverpool, United Kingdom; Kenema Government Hospital, Ministry of Health and Sanitation, Sierra Leone; Tulane University Health Sciences Center, New Orleans, Louisiana; U.S. Naval Medical Research Unit No. 6, Lima, - - 2014
The outbreak of Ebola virus disease (EVD) in West Africa has outstripped available resources. Novel strategies are desperately needed to streamline operations. The present norm of requiring negative results on polymerase chain reaction for EVD convalescent patients to be discharged is not evidence-based and often results in asymptomatic patients competing ...
Poulter Katherine K Local Care Direct, Wharfedale Hospital, Otley, West Yorkshire, University of - - 2014
As population mobility and global interconnectedness increase, and more people travel to tropical regions, the risk of importing infectious diseases has become higher than ever before. This risk has been highlighted by the recent outbreak in West Africa of the Ebola virus, isolated cases of which have been reported in ...
McAlister Vivian V Co-rédacteur, Journal canadien de - - 2014
Martin-Moreno Jose M JM Department of Preventive Medicine and Public Health and INCLIVA Research Institute, University of Valencia, Valencia 46010, Spain Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, - - 2014
Stockley Simon N SN Eaglescliffe, Stockton-On-Tees, North East - - 2014
Brizendine Kyle D KD Department of Infectious Disease, Cleveland - - 2014
Ebola virus causes a hemorrhagic fever with a high case-fatality rate. Treatment remains supportive although a variety of specific treatments are still in the early stages of investigation. This report reviews the clinical virology of Ebola virus, the reported proposed treatments, and the current outbreak.
Kennedy Maureen Shawn MS AJN Editor-in-Chief E-mail: - - 2014
What have we learned from this crisis?
Wallis Laura - - 2014
Nurses at Emory University Hospital shine.
Mandell Brian F - - 2014
McAlister Vivian V Coeditor, Canadian Journal of - - 2014
Carson G L GL International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) Coordinating Centre, University of Oxford, Centre for Tropical Medicine, NDM Research Building, Old Road Campus, Roosevelt Drive, Oxford, OX3 7FZ, UK - - 2014
Wainberg Mark A - - 2014
No abstract.
To Kelvin K W KK State Key Laboratory for Emerging Infectious Diseases, the University of Hong Kong, Hong Kong, China; Carol Yu Centre for Infection, the University of Hong Kong, Hong Kong, China; Research Centre of Infection and Immunology, the University of Hong Kong, Hong Kong, China; Department of Microbiology, the University of Hong Kong, Hong Kong, - - 2014
Ebolavirus can cause a highly fatal and panic-generating human disease which may jump from bats to other mammals and human. High viral loads in body fluids allow efficient transmission by contact. Lack of effective antivirals, vaccines and public health infrastructures in parts of Africa allow the disease to spread unchecked.
Pasquier Pierre P Intensive Care Unit, Bégin Military Teaching Hospital, Saint-Mandé, France, - - 2014
Palomo Adolfo Martínez AM Center for Advanced Studies, Molecular Pathogenesis, Avenida IPN 2508, Mexico City (D.F.) 01030, Mexico. E-mail: - - 2014
The Ebola epidemic exemplifies the importance of social determinants of health: poverty and illiteracy, among others.Journal of Public Health Policy advance online publication, 27 November 2014; doi:10.1057/jphp.2014.50.
Mentré France F INSERM, IAME, UMR 1137, F-75018 Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Paris, France. Electronic address: - - 2014
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