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Gancevičienė, Rūta
Background: Acne is a chronic inflammatory disorder of the pilosebaceous unit (PSU). The PSU is an immunocompetent organ, and the sebaceous gland (SG) exhibits an independent peripheral endocrine function and expresses receptors for neuropeptides (NP). The presence of a complete corticotrophin-releasing hormone (CRH)/CRH receptor (CRHR) system in human sebocytes has ...
Wang Y Y Division of Dermatology, Department of Medicine, University of California, 3525 John Hopkins Court, San Diego, CA 92121, - - 2014
Previously, we demonstrated that Propionibacterium acnes, a human skin commensal bacterium, ferments glycerol into short-chain fatty acids, including propionic acid. Propionic acid suppressed the growth of Staphylococcus aureus USA300, a community-acquired methicillin-resistant bacterium, in vitro and in vivo. In this study, it is demonstrated that the anti-USA300 activity of propionic ...
Coyle Christine E CE Froedtert Lutheran Memorial Hospital Clinical Cancer Center, Milwaukee, Wisconsin. Christine E. Coyle, MSN, RN, OCN®, is a nurse educator at the Clinical Cancer Center-Day Hospital at Froedtert Lutheran Memorial Hospital in Milwaukee, Wisconsin. Her role is to improve nursing practice through standardization of continuing education and training for the specialty of oncology. Julie Griffie, MSN, RN, AOCN®, ACNS-BC, APRN, is the manager of nursing practice for the Clinical Cancer Center at Froedtert Lutheran Memorial Hospital in Milwaukee, Wisconsin. She has been a clinical nurse specialist for more than 30 years, specializing in oncology. She has written a number of publications related to nursing practice standards. Lynn M. Czaplewski, MS, RN, ACNS-BC, CRNI®, AOCNS®, is a clinical nurse specialist for the Cancer Center-Day Hospital at Froedtert Lutheran Memorial Hospital in Milwaukee, Wisconsin. She served as president of the Infusion Nurses Society from 2006 to 2007 and has been named CRNI® of the - - 2014
Administration of chemotherapy agents can give rise to many safety issues. Extravasation of a vesicant agent causes tissue blistering and necrosis. This complication of chemotherapy administration causes additional pain and suffering in patients who are already suffering with a diagnosis of cancer. Nurses hold key responsibilities for educating patients about ...
Schleifer Sarah Joy SJ Sarah Joy Schleifer, MSN, RN, ACNS-BC, CCRN, is a critical care CNS at Sharp Grossmont Hospital in La Mesa, California. She obtained her BSN and MSN from Point Loma Nazarene University in San Diego, California. She teaches new critical care RNs at a county-wide critical care intern program and is the marketing chair for the San Diego chapter of the AACN. Her areas of research interests include patient education, improvement of the patient experience, nurse/provider communication and patient centered care coordination. Karen Carroll, MS, RN, CCNS, CCRN, PCCN, is a critical care CNS at VA Medical Center San Diego Healthcare System. Both of Karen's graduate and undergraduate degrees are from San Diego State University (SDSU). She teaches undergraduate and graduate courses at SDSU in addition to PCCN review courses in the community. Ms Carroll's is currently working on research regarding inpatient cardiopulmonary arrests and the impact of a performance improvement based resuscitation training program to decrease cardiopulmonary arrests and improves survival at the VA San Diego Healthcare System. Marthe J. Moseley, PhD, MSN, RN, CCNS, is associate director of Clinical Practice in the Office of Nursing Services with the Department of Veterans Affairs. She holds a full Professor position at Rocky Mountain University of Health Professions in Provo, Utah and an Adjunct Professor position at the University of Texas Health Science Center School of Nursing at San Antonio, Texas. Dr Moseley obtained her BSN from Jamestown College and her MSN and PhD at the University of Texas Health Science Center in San Antonio, TX. She is on the editorial board for several critical care journals and is one of the team of three who write the "Introduction to Critical Care," a premier textbook for undergraduate students with course work in the ICU - - 2014
Over the last 5 years, telemedicine has developed nursing roles that differ from traditional bedside care. In the midst of this transition, current competency development models focused on task completion may not be the most effective form of proficiency validation. The procedure of competency creation for the role of tele-intensive ...
Dreno Brigitte B Department of Dermato-Cancerology, University of Nantes, Nantes, - - 2014
Background/Objectives: Widespread use of antibiotics in all areas of medicine has led to significant problems with antimicrobial resistance, which have begun to compromise the usefulness of antibiotics. Antibiotics have long been a keystone of acne therapy. There is a large population of patients with acne and antibiotic therapy is often ...
Padilla-España Laura L Servicio de Dermatología, Hospital Costa del Sol, Marbella, Málaga, España. Electronic address: - - 2014
There are certain skin disorders such as vitiligo, acne, vascular malformations and postoperative scars that can affect the quality of life of children and especially adolescents. It can become an obstacle to their psychosocial development. A review was conducted on 4 patients with vitiligo located on face, who took part ...
Pohl Alexa - - 2014
Prenatal exposure to increased androgens has been implicated in both polycystic ovary syndrome (PCOS) and autism spectrum conditions (ASC), suggesting that PCOS may be increased among women with ASC. One study suggested elevated steroidopathic symptoms ('steroidopathy') in women with ASC. As the symptoms are not independent, we conducted a latent ...
Cecchetti Stella - - 2014
Erosive degenerative disc disease, also known as Modic type 1 changes, is usually characterized by low back pain with an inflammatory pain pattern, as seen in spondyloarthropathies. Intravenous pamidronate has proven to be effective in patients with ankylosing spondylitis who are refractory to nonsteroidal antiinflammatory drugs, and in painful bone ...
Freira Sílvia S Adolescent Medicine Clinic, Department of Pediatrics, Hospital de Santa Maria, Lisbon, - - 2014
SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome includes both dermatological and rheumatologic symptoms. Being a rare condition, the diagnosis is frequently late. The authors report a case of a 13-year-old boy diagnosed with synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome with unusual severe systemic repercussions. The patient presented with ...
Grosso Matthew J MJ Department of Orthopedic Surgery, Case Western Reserve University, Cleveland, OH, - - 2014
Infection after shoulder arthroplasty can present a diagnostic challenge. The purpose of this study was to evaluate the utility of serum interleukin-6 (IL-6) levels in diagnosis of periprosthetic infection in patients undergoing revision shoulder arthroplasty. We prospectively enrolled 69 patients who underwent revision shoulder arthroplasty at one institution. All patients ...
Vitek Wendy W Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New - - 2014
Adolescence is a time of rapidly changing reproductive hormones and menstrual patterns making diagnosis of polycystic ovary syndrome (PCOS) challenging in this population. Nonetheless, there is significant concern that the metabolic and reproductive abnormalities that emerge at adolescence associated with a diagnosis of PCOS have lifelong implications for the individual. ...
Agapova Sophia E SE Division of Pediatric Endocrinology, Diabetes, and Metabolism, Department of Pediatrics, Columbia University Medical Center, New York, New - - 2014
Although the diagnostic criteria for polycystic ovary syndrome (PCOS) have become less stringent over the years, determination of the minimum diagnostic features in adolescents is still an area of controversy. Of particular concern is that many of the features considered to be diagnostic for PCOS may evolve over time and ...
Lee Young H YH Department of Dermatology, Division of Health Services Research. Electronic address: - - 2014
Duration of oral antibiotic therapy in acne has not been widely studied. Recent guidelines suggest it should be limited to 3 to 6 months. We sought to compare the duration of oral antibiotic use with recent guidelines and determine the potential cost-savings related to shortened durations. This is a retrospective ...
Karnik Jwala J Suneva Medical Inc, Santa - - 2014
Acne scarring remains a stubborn clinical problem. Few treatments have been shown to be definitely effective for this problem. Polymethylmethacrylate (PMMA) microspheres in collagen (ArteFill, Suneva Medical Inc, Santa Barbara, CA) have shown long-term benefit for nasolabial fold treatment. A pilot study has shown benefit for PMMA-collagen in atrophic acne scarring. ...
Honour John W JW Institute of Women's Health, University College London, London, - - 2014
17-Hydroxyprogesterone (17-OHP) is an intermediate steroid in the adrenal biosynthetic pathway from cholesterol to cortisol and is the substrate for steroid 21-hydroxylase. An inherited deficiency of 21-hydroxylase leads to greatly increased serum concentrations of 17-OHP, while the absence of cortisol synthesis causes an increase in adrenocorticotrophic hormone. The classical congenital ...
Kwah Joann J Division of Gastroenterology, Montefiore Medical Center, 111 East 210th Street, Bronx, NY, 10467, USA, - - 2014
Current guidelines for surveillance of colonic neoplasia are based on data from predominantly white populations, yet whether these recommendations are applicable to blacks is unknown. To define the prevalence of advanced colorectal neoplasia (ACN) among whites and blacks undergoing surveillance colonoscopy. This was a retrospective, cross-sectional analysis of asymptomatic, average-risk ...
Dréno Brigitte B Dept of Dermato-Cancerology, University of Nantes, Place Alexis Ricordeau, 44093, Nantes, - - 2014
Background: The efficacy and safety of clindamycin phosphate 1.2%/tretinoin 0.025% (Clin-RA) were evaluated in three 12-week randomised studies. Objectives: To perform a pooled analysis of data from these studies to evaluate its efficacy and safety in a larger population, in adolescents and in different acne severities. Materials & Methods: 4550 ...
Ozkol Hatice Uce HU Faculty of Medicine, Department of Dermatology, Yuzuncu Yil University , Van , Turkey - - 2014
Abstract Objectives: There are only a few earlier studies suggesting relationship between isotretinoin treatment and oxidative stress however, their results are conflicting. Therefore we aimed to concretize the influence of isotretinoin treatment on oxidant/antioxidant status together with paraoxonase-1 (PON1) activity for the first time. Methods: The study was performed on ...
Cameli Norma N Department of Dermatology, San Gallicano Institute IRCCS, Rome, - - 2014
The therapeutic approach to the treatment of acne scars and photoaging varies according to the type of lesion. Traditional carbon dioxide (CO2 ) laser is associated with long healing times, persistent erythema, and high risk of post-inflammatory hyperpigmentation. Fractional laser technology, which involves the application of microscopic beams of pixilated ...
Carrington Jane M JM College of Nursing, The University of Arizona, Tucson (Drs Carrington and Shea); Department of Information Technology, New York-Presbyterian Hospital (Ms Tiase); ACNS/Research, VA Salt Lake City Health Care System, Utah (Dr Estrada); College of Nursing, University of Utah, Salt Lake City (Dr Estrada); and Biomedical Informatics Department, Uniform Services University of the Health Sciences, Bethesda, Maryland (Dr - - 2014
The Nursing Informatics Year in Review 2013 revealed an increase in publications associated with nursing education. Specifically, the articles addressed technology in nursing curricula, use of technology to teach nursing education, and use of technology to form collaborative relationships. In this article we present questions such as: how do these ...
Bhate K K Centre of Evidence Based Dermatology, University of Nottingham, Nottingham, - - 2014
This review summarizes important clinical developments in acne vulgaris identified from 17 systematic reviews published between February 2011 and August 2012. Regarding causes, Demodex mites have been shown to be associated with both acne vulgaris and rosacea, although it is unclear if their eradication improves either disease. Some weak evidence ...
Alexis Andrew A Department of Dermatology, Skin of Color Center, St. Luke's-Roosevelt Hospital, 1090 Amsterdam Avenue, Suite 11 B, New York, NY 10025, USA. Electronic address: - - 2014
Pseudofolliculitis barbae and folliculitis keloidalis nuchae are chronic follicular disorders disproportionately affecting men of African ancestry. This article explores the etiology, pathogenesis, treatment, and prevention strategies of these conditions. Effective treatment and prevention of these disorders involves pharmacologic and procedural interventions as well as behavioral modifications.
Moran Katherine K Katherine Moran, DNP, RN, CDE, is an Assistant Professor, McAuley School of Nursing, University of Detroit Mercy, Detroit, Michigan. Rosanne Burson, DNP, ACNS-BC, CDE, is an Assistant Professor, McAuley School of Nursing, University of Detroit Mercy, Detroit, - - 2014
Hellmann-Regen Julian J Clinical Neurobiology, Department of Psychiatry, Charité University Medicine Berlin, Campus Benjamin Franklin, Berlin, - - 2014
For decades, retinoic acid (RA) is known as the most potent therapeutic option in the therapy of acne and altered homeostasis of endogenous retinoids has been discussed in the context of acne pathogenesis. Besides retinoids, antibiotics such as tetracyclines or erythromycin are well established in acne pharmacotherapy. Accumulating evidence points ...
Iwamoto Shigeyoshi S Department of Surgery, Kansai Medical University Takii Hospital, 10-15 Fumizono-cho, Moriguchi-city, Osaka 570-8507, Japan. - - 2014
This study was the first multicenter phase II study of cetuximab plus folinic acid/5-fluorouracil/irinotecan (FOLFIRI) in KRAS wild-type mCRC as a second-line treatment in Japan including BRAF and PIK3CA genotyping. Tumors of 112 pre-registered patients were genotyped for KRAS, BRAF, and PIK3CA. The primary study end-point was response rate, and ...
Luo Changqin C Department of Clinical Oncology, The First Affiliated Hospital of Xi'an Jiaotong University College of Medicine, Xi'an, Shaanxi 710061, P.R. - - 2014
The aim of this study was to explore the clinical characteristics of and treatment strategies for interstitial pneumonia induced by gefitinib in patients with advanced non-small cell lung cancer (NSCLC). The detailed clinical data of one patient with NSCLC and gefitinib-induced interstitial pneumonia were compiled and a review of relevant ...
Lynde Charles - - 2014
Background:Most treatment guidelines for acne are based on clinical severity. Our objective was to expand that approach to one that also comprised individualized patient features: a case-based approach.Methods:An expert panel of Canadian dermatologists was established to develop demographic and clinical features considered to be particularly important in acne treatment selection. ...
Harvey Alison - - 2014
Acne vulgaris is a common skin disease in which abnormal desquamation, excess sebum production, proliferation of Propionibacterium acnes, and production of proinflammatory mediators all contribute to the pathogenesis of the disease. A review of the literature shows that our current understanding of acne pathogenesis continues to evolve. Recent data suggests ...
Kircik Leon H - - 2014
Topical tretinoin has been a standard treatment for acne vulgaris for more than 4 decades. While tretinoin has demonstrated proven efficacy in the treatment of acne lesions, it also is associated with the potential for skin irritation. Newer formulations have been designed to optimize both the drug concentration and the ...
Mahmood Shereen N - - 2014
The prevalence of adult acne in the US appears to be increasing over the last few decades. But what's behind the rise: is it nature or nurture? We are well aware that genetics can strongly influence a patient's risk of developing acne. However, significant changes in germline genetic variants are ...
Jonsson Eythor Örn EÖ Department of Orthopedic Surgery , Landspitali University Hospital , - - 2014
Background and purpose - Previous work has shown that despite preventive measures, intraoperative contamination of joint replacements is still common, although most of these patients seem to do well in follow-up of up to 5 years. We analyzed the prevalence and bacteriology of intraoperative contamination of primary joint replacement and ...
Oztürk Savaş S Department of Dermatology, Elazig Education and Research Hospital , Elazig , Turkey - - 2014
Abstract Background: Isotretinoin affects the levels of female hormones and ovaries in patients with severe acne. Objective: This study evaluated the effects of isotretinoin on the ovarian reserve and levels of female hormones in patients with severe acne. Methods: Thirty-two female patients with severe acne were enrolled. All the patients ...
Ji You-Xin YX Department of Oncology, Qingdao Central Hospital, The Second Affiliated Hospital of Qingdao University, Qingdao 266042, - - 2014
Objective To explore the efficacy and safty of sorafenib in Child-Pugh class B to class C hepatocellular carcinoma (HCC).Methods In this three-center open-label study from November 2011 to May 2013, we randomly assigned 189 patients with advanced Child-Pugh class B or C HCC patients into two groups, one group with ...
Itoh Tomohiro T Laboratory of Aquatic Food Science, Department of Fisheries, Faculty of Agriculture, Kinki University, 3327-204 Nakamachi, Nara 631-8505, Japan. Electronic address: - - 2014
Propionibacterium acnes is the primary pathogenic agent responsible for acne vulgaris on the skin and hair follicles. Overgrowth of this bacterium inhibits growth and promotes follicular inflammation, with an associated increase in pro-inflammatory cytokine production. P. acnes has therefore been considered the main target for the prevention and medical treatment ...
Walter Veronika - - 2014
A 48 year old patient with dilated cardiomyopathy and chronic acne inversa underwent implantation of a LVAD system (Heartmate II, Thoratec, USA) March 2011. During 2011 and 2012 the patient was repeatedly readmitted for treatment of driveline infection with MRSA. Colonization was controlled with Linezolid and Rifampicin however reoccurred after ...
Ianni Federica F Department of Pharmaceutical Sciences, University of Perugia, Via del Liceo 1, 06123 Perugia, Italy; Institute of Pharmaceutical Sciences, University of Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, - - 2014
While aliphatic 2-hydroxyalkanoic acids have been more or less successfully enantioseparated with various chiral stationary phases by HPLC and GC, analogous applications on underivatized aliphatic 3-hydroxyalkanoic acids are completely absent in the scientific literature. With the aim of closing this gap, the enantioseparation of 3-hydroxybutyric acid, 3-hydroxydecanoic acid and 3-hydroxymyristic ...
Shinoda Koichiro K First Department of Internal Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, - - 2014
Orogenital ulcer is one of the clinical manifestations of Behçet's disease (BD). However, orogenital ulcer may be observed in various conditions, such as complex aphthous dermatitis and herpes simplex virus infections. Therefore, orogenital ulcer along with skin lesions, including acne or erythema nodosum, may be misdiagnosed as BD, but is ...
Rahman Salwa Abdel SA National Organization of Drug Control and Research (NODCAR) , Cairo , Egypt - - 2014
Abstract Tretinoin (TRT) is a widely used retinoid for the topical treatment of acne, photo-aged skin, psoriasis and skin cancer which makes it a good candidate for topical formulation. Yet side effects, like redness, swelling, peeling, blistering and, erythema, in addition to its high lipophilicity make this challenging. Therefore, the ...
Ari Süleyman - - 2014
Tar is one example of a plant product used in folk medicine and it is obtained from Pinus nigra Arn. subsp. pallasiana (Lamb.) Holmboe, which is very common in the West Anatolian Region. Old trees that are good for kindling and have thick trucks are preferred to obtain tar. Tar ...
van der Zee H H HH Department of Dermatology, Erasmus MC, University Medical Center, - - 2014
Dear Editor, hidradenitis suppurativa also known as acne inversa is an inflammatory skin disease characterized by painful nodules, abscesses and fistulas(1) . The groin, axillae, and buttocks are the most frequently affected skin areas(2) . Disease-associated factors include smoking, obesity, mechanical friction, genetic predisposition, hormonal influences and an aberrant innate ...
Pomerantz H H Dermatoepidemiology Unit, VA Medical Center, Providence, Rhode Island, USA; Department of Dermatology, Brown University, Providence, Rhode Island, - - 2014
Topical tretinoin is commonly prescribed, but its frequent adverse effects are barriers to use. Predictors of resistance or susceptibility to retinoid irritation are not known. We sought to identify baseline patient characteristics associated with adverse effects of topical tretinoin. This cohort study used data collected from 324 participants randomized to ...
Bay Esther H EH Questions or comments about this article may be directed to Esther H. Bay, PhD ACNS-BC, at pdq@umich.edu. She is a Clinical Associate Professor, School of Nursing, University of Michigan, Ann Arbor, MI. Kattlynn S. Chartier, BSN(c), is a Senior Honors Student, University of Michigan, Ann Arbor, MI. This manuscript was authored collaboratively by Esther H. Bay and Kattlyn S. - - 2014
Emerging data suggest that traumatic brain injury (TBI) is a disease process with considerable long-range morbidities requiring lifelong monitoring and treatment. Multiple chronic morbidities develop across the life span after TBI, including mental health disorders, headaches, seizures, and neuroendocrine imbalances as well as chronic diseases. Still, there has been limited ...
Almandoz M C MC Área de Química Física, Facultad de Química Bioquímica y Farmacia, Instituto Multidisciplinario de Investigaciones Biológicas (IMIBIO-SL) CONICET, Universidad Nacional de San Luis, 5700 San Luis, Argentina. Electronic address: - - 2014
The solvatochromic behavior of trimethoprim (TMP) was analyzed using UV-Vis spectroscopy and DFT methods in neat and binary aqueous solvent mixtures. The effects of solvent dipolarity/polarizability and solvent-solute hydrogen bonding interactions on the absorption maxima were evaluated by means of the linear solvation energy relationship concept of Kamlet and Taft. ...
Im So Hee SH Department of Drug Discovery Platform Technology, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Republic of Korea; College of Pharmacy, Chungnam National University, Daejeon, Republic of - - 2014
The object of the present study was to develop and validate an assay method of mesoridazine in rat plasma using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Plasma samples from rats were prepared by simple protein precipitation and injected onto the LC-MS/MS system for quantification. Mesoridazine and chlorpromazine as an internal standard ...
Verhave Jacobien J Nephrology, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, - - 2014
Conversion from a calcineurin-inhibitor-based to a rapamycin-based immunosuppression may preserve kidney graft function. The side effects of rapamycin can limit its usefulness, but their management and evolution are rarely reported in clinical trials. We performed a retrospective cohort study in patients transplanted before December 31st, 2008 and who received rapamycin ...
Dosal Jacquelyn J Department of Dermatology & Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, - - 2014
Yuan Xing-Hua XH Department of Dermatology and Venereology, First Hospital of Jilin University, Changchun, China; Department of Dermatology and Venereology, Yanbian University Hospital, Yanji, - - 2014
Ablative 10,600-nm carbon dioxide (CO2 ) fractional laser treatments have shown favorable outcomes for atrophic acne scars. To compare the efficacy and complications of fractional CO2 laser treatments with different fluences and densities for acne scars. Twenty patients were treated using a single session of fractional CO2 laser in Deep ...
Aubin G G GG Service de Bactériologie-Hygiène, Institut de biologie des hôpitaux de Nantes, CHU de Nantes, 9, quai Moncousu, 44093 Nantes cedex 01, France; EA3826 Thérapeutiques cliniques et expérimentales des infections, Université de Nantes, faculté de médecine, 44000 Nantes, - - 2014
Propionibacterium acnes colonizes the lipid-rich sebaceous glands of the skin. This preferential anaerobic bacterium is easily identified if cultures are prolonged. It is involved in the inflammation process of acne, but until recently, it was neglected in other clinical presentations. Despite a reported low virulence, the new genomic, transcriptomic, and ...
Meng Xianghe - - 2014
A simple procedure for the determination of total phospholipid (TPL) in edible oils was developed by combining a single-step, in situ methanol/acetonitrile (MeOH/ACN) extraction of the oil sample followed by Fourier transform infrared (FTIR) spectroscopic analysis of the extract. Spectral analysis of extracts in a 25 m CaF2 cell obtained ...
Castillo-Arenas E E Área Sanitaria Sur de Granada, Granada, Spain. Electronic address: - - 2014
Skin conditions are among the main reasons for seeking primary health care. Primary care physicians (PCPs) must diagnose skin conditions and determine their impact, and must therefore incorporate the relevant knowledge and skills into their education. The present study analyzes the reasons for primary care referral to dermatology (referral demand) ...
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  • Acne.  KLIGMAN A M - 1962
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