Search Results
Results 1 - 50 of 96

Current sort is by relevancy. Click to sort by publication date

1 2 >
Files Matthew D - - 2009
We present an 8-year-old male with Loeffler endocarditis and acute lymphoblastic leukemia with hypereosinophilia (ALL/Eo) who initially presented with a 3-month history of peripheral eosinophilia thought to be due to visceral larval migrans. Despite treatment for Toxocara, his leukocytosis persisted and he developed mitral valve insufficiency and congestive heart failure. ...
Relevancy Score: Relevancy Score: 1000
Lofiego Carla - - 2005
Little is known about the morphological and functional evolution of ventricular abnormalities in Loeffler endocarditis. We describe 5 patients, including 3 with long-term echocardiographic follow-up, in whom apical obliteration due to fibro-thrombotic thickening of the endocardium showed favorable patterns of evolution. In one patient there was almost complete resolution of ...
Relevancy Score: Relevancy Score: 1000
Aydoğdu Sinan - - 2010
A 15-year-old boy who was admitted to the neurology department had multiple cerebral infarcts on cranial magnetic resonance imaging. A transthoracic echocardiogram revealed myocardial thickening and apical thrombus in the left ventricle suggesting Loeffler endocarditis. There was remarkable hypereosinophilia on the haemogram. An investigation for the aetiology of hypereosinophilia led ...
Relevancy Score: Relevancy Score: 961
Benezet-Mazuecos Juan - - 2007
Loeffler endocarditis, eosinophilic endomyocardial disease or fibroplastic endocarditis appears to be a subcategory of the Hypereosinophilic syndrome in which the heart is predominantly involved. It is an uncommon myocardial disease, thought to be secondary to eosinophils damage, characterized by fibrous thickening of the endocardium of one or both ventricles, leading ...
Relevancy Score: Relevancy Score: 961
Kandemir Cağlayan - - 2009
Relevancy Score: Relevancy Score: 958
Keivanidou Anastasia - - 2013
Loefler endocarditis is a potential fatal adverse event of hypereosinophilic syndrome. We report a case of a 5-year-old girl diagnosed with peripheral hypereosinophilia refractory to corticosteroid therapy who developed eosinophilia-related endocarditis. Echocardiography revealed infiltration of the left ventricular free wall and the posterior mitral leaflet causing moderate mitral regurgitation. Genetic ...
Relevancy Score: Relevancy Score: 787
Pop C - - 1998
The authors report a case of fibroplastic endocarditis discovered during echocardiography in an asymptomatic patient in the context of assessment of systematized electrocardiographic modifications. The diagnosis, strongly suspected on the basis of the cardiac MRI findings, was finally confirmed by endocardial biopsy.
Relevancy Score: Relevancy Score: 603
Yalonetsky Sergey - - 2008
We present a case of nearly total posterior mitral leaflet destruction due to Loeffler endocarditis associated with Hodgkin's lymphoma in a 15-year-old adolescent. The patient was treated medically with subsequent surgical mitral valve replacement. Cardiac aspects of hypereosinophilic syndrome are also discussed.
Relevancy Score: Relevancy Score: 585
Esposito Antonio - - 2010
Churg-Strauss syndrome can be associated with Loeffler-like eosinophilic endocarditis. We report a case of a young woman in which the diagnosis of Churg-Strauss syndrome was made subsequently to the magnetic resonance demonstration of eosinophilic endocarditis associated to left ventricle apical thrombosis. In our report, this rare condition evolved in an ...
Relevancy Score: Relevancy Score: 513
Langwieser Nicolas N I. Medizinische Klinik und Poliklinik, Klinikum Rechts der Isar, Technische Universität München, Ismaningerstrasse 22, 81675 Munich, - - 2014
Relevancy Score: Relevancy Score: 483
Lin Chih-Hsiang - - 2009
PURPOSE: Idiopathic hypereosinophilia syndrome (iHES) is classically defined as prolonged peripheral eosinophilia and multiple organ involvement. The involvement of the heart can lead to intraventricular thrombus because of infiltration of the endomyocardium by eosinophils. Cerebral infarction has been ascribed to thromboembolic events originating from intraventricular thrombus. CASE REPORT: A 67 ...
Relevancy Score: Relevancy Score: 479
González Torrecilla E - - 1989
We present an uncommon case of idiopathic hypereosinophilic syndrome with cardiac involvement (fibroplastic parietal endocarditis --Löffler's disease--) in a 48-year-old female with congestive heart failure and hypereosinophilia. The 2-D echo findings (biventricular apical obliteration by echogenic endomyocardial proliferations with normal systolic inward motion) were the clue for the diagnosis that ...
Relevancy Score: Relevancy Score: 454
Bomken Simon S Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK; Department of Paediatric Oncology, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, - - 2014
Hypereosinophilia is a rare phenomenon associated with childhood malignancy, predominantly acute lymphoblastic leukaemia. Causation is unclear and likely to have multiple mechanisms. We report a six year old boy presenting with hypereosinophilia and associated Loeffler endocarditis. Three months following his initial hypereosinophilia he developed cutaneous B-lymphoblastic lymphoma. Re-analysis of apparently ...
Relevancy Score: Relevancy Score: 450
Ennezat Pierre Vladimir - - 2013
The pathogenesis of endomyocardial fibrosis (EMF) is poorly understood. EMF may result from autoimmune scarring of the endocardium. Clinically, EMF presents as a restrictive cardiomyopathy. EMF is commonly reported in tropical countries. In Western countries, EMF is associated with hypereosinophilia and reported as Loeffler endocarditis. We report a Caucasian patient ...
Relevancy Score: Relevancy Score: 429
Rapezzi C - - 1993
The restrictive cardiomyopathies are the least common of the 3 major categories of cardiomyopathic disorders seen in Western countries. According to the report of the WHO/ISFC Task Force the term restrictive cardiomyopathy applies to only 2 conditions: endomyocardial fibrosis and Loeffler endocarditis while many specific myocardial diseases can develop a ...
Relevancy Score: Relevancy Score: 398
Glassey F - - 1987
We report a case of Löffler's endocarditis in a 60-year-old woman with multiple lymphadenopathies, blood eosinophilia and acute heart failure. The eosinophilia developed over a six-month period to a maximum of 54.5% eosinophiles for 7600 X 10(9) leukocytes/l. Five weeks before death lymph node biopsy revealed Hodgkin's disease with mixed ...
Relevancy Score: Relevancy Score: 378
Alter Peter - - 2006
Cardiac involvement frequently occurs in hypereosinophilic syndrome. The endocardium seems to be most susceptible to disturbances deriving from eosinophilia as seen in Loeffler's endocarditis. Hypereosinophilia and cardiac involvement are also seen in Churg-Strauss syndrome. The present report deals with a patient with Churg-Strauss syndrome who exhibited marked endomyocardial fibrosis that ...
Relevancy Score: Relevancy Score: 364
LOEFFLER W - - 1952
Relevancy Score: Relevancy Score: 343
Campbell Dean - - 2013
We report a case of bacterial endocarditis due to Erysipelothrix rhusiopathiae in a homeless man with no animal exposure. His course was complicated by an allergic reaction to ampicillin, urinary bladder infection, respiratory failure, and acute kidney injury. He recovered completely after aortic valve replacement and a 6-week course of ...
Relevancy Score: Relevancy Score: 322
Keung Yi Kong - - 2002
Chronic myelocytic leukemia (CML) is a chronic myeloproliferative disorder characterized by cytogenetic or molecular evidence of Philadelphia (Ph) chromosome, t(9;22)(q34;q11). Mild to moderate eosinophilia is commonly seen in CML. However, eosinophilia as a dominant feature of CML is extremely rare. We describe a case of Ph(-) CML with eosinophilia. Loeffler ...
Relevancy Score: Relevancy Score: 318
Khouzam Rami N - - 2005
The case of a 57-year-old male with a history significant for myeloproliferative disease, chronic renal failure, hypertension, and prostate cancer is described. His complete blood count was remarkable for neutrophilia and, notably, eosinophilia. Subsequent to two syncopal episodes, a transthoracic echocardiogram was performed as part of the workup, which showed ...
Relevancy Score: Relevancy Score: 282
Entenza J M - - 2005
Cpl-1, a pneumococcal phage lytic enzyme, was tested in rats with experimental endocarditis due to Streptococcus pneumoniae WB4. High-dose regimen Cpl-1 eliminated pneumococci from blood within 30 min and decreased bacterial titers in vegetations (>4 log10 CFU/g) within 2 h. Rapid bacterial lysis induced by Cpl-1 treatment increased cytokine secretion ...
Relevancy Score: Relevancy Score: 275
Kanra G - - 1985
The Ouchterlony - Elek gel diffusion test was performed in twenty-nine patients having a positive culture result for diphtheria bacilli on Loeffler and tellurite agars in January and February, 1984 and toxin production was detected in 20 of them. Except one adult patient, the cases ranged in age 2 and ...
Relevancy Score: Relevancy Score: 223
Yabuno Kaori K Division of Infection Control and Prevention, Osaka University Hospital, Osaka, Japan ; Department of Pharmacy, Osaka University Hospital, Osaka, - - 2013
The recommended daptomycin dosage is 4 or 6 mg/kg/day for the treatment of complicated skin and soft tissue infections or for Staphylococcus aureus bacteremia, endocarditis, and osteomyelitis. Every other day administration is usually recommended for patients with mild to moderate renal impairment. Higher doses (>6 mg/kg/day) have been explored as ...
Relevancy Score: Relevancy Score: 167
Argemi Xavier X Infectious Diseases Department, Strasbourg University Hospital, Strasbourg, France. - - 2013
Enterococcus faecalis (E. faecalis) has become a major leading cause of nosocomial endocarditis. Treatment of such infections remains problematic and new therapeutic options are needed. Nine E. faecalis strains were tested: six obtained from patients presenting endocarditis, one with isolated bacteremia, and two reference strains. Antibiotics included daptomycin, alone or ...
Relevancy Score: Relevancy Score: 166
Gonzalez-Ruiz Armando - - 2011
To describe the patient populations and infections being treated with daptomycin, as well as the efficacy and safety outcomes. Data from the European Cubicin Outcomes Registry and Experience (EU-CORESM), retrospectively collected at 118 institutions between January 2006 and August 2008, were analysed. Daptomycin treatment was documented in 1127 patients with ...
Relevancy Score: Relevancy Score: 140
Nygård Siri Tandberg - - 2014
Severe sepsis is recognized as an inflammatory response causing organ dysfunction in patients with infection. Antimicrobial therapy is the mainstay of treatment. There is an ongoing demand for local surveillance of sepsis aetiology and monitoring of empirical treatment recommendations. The present study was established to describe the characteristics, quality of ...
Relevancy Score: Relevancy Score: 99
Seaton R Andrew - - 2013
A retrospective analysis of data from patients receiving daptomycin as outpatient parenteral antimicrobial therapy (OPAT) within the European Cubicin Outcomes Registry and Experience (EU-CORESM) was performed. Of 4592 enrolled patients in 15 countries, 550 (12%) received daptomycin OPAT. Of these, 149 (27%) received daptomycin without hospital admission, 84% had significant ...
Relevancy Score: Relevancy Score: 93
Panning Marcus - - 2008
BACKGROUND: Coxiella burnetii is the causative agent of Q-fever, a widespread zoonosis. Due to its high environmental stability and infectivity it is regarded as a category B biological weapon agent. In domestic animals infection remains either asymptomatic or presents as infertility or abortion. Clinical presentation in humans can range from ...
Relevancy Score: Relevancy Score: 89
Lim Joanna - - 2013
An 81 year old female patient diagnosed with a chronic low grade hypereosinophilic syndrome presented with angina and dyspnoea. She was managed for a non-ST elevated myocardial infarction since her troponin levels were elevated. On day 5, she suffered an acute clinical deterioration with type I respiratory failure and cardiogenic ...
Relevancy Score: Relevancy Score: 87
Debl Kurt - - 2008
We report the diagnostic potential of cardiovascular magnetic resonance (CMR) to visualize the time course of eosinophilic myocarditis upon successful treatment. A 50-year-old man was admitted with a progressive heart failure. Endomyocardial biopsies were taken from the left ventricle because of a white blood cell count of 17000/mm3 with 41% ...
Relevancy Score: Relevancy Score: 80
You Sung-Hye - - 2009
Eosinophilic endomyocarditis is a manifestation of hypereosinophilic syndrome, characterized by prolonged (>6 months), unexplained peripheral blood eosinophilia (>1,500 cells/mm(3)) with end-organ damage in unknown causes. We report a case of a 42-year-old patient who developed eosinophilic endomyocarditis following upper respiratory tract symptoms for 2 months. Additionally, endomyocarditis was combined with ...
Relevancy Score: Relevancy Score: 79
1 2 >