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Dewan D M - - 1982
The pH and volume of gastric contents were examined in 60 patients undergoing elective Caesarean Section under thiopentone, nitrous oxide-oxygen, succinylcholine anaesthesia. All patients received Gelusil 30 ml per os preoperatively, while 20 were given atropine 7 microgram X kg-1 and another 20 glycopyrrolate 4 microgram X kg-1 intramuscularly along ...
Relevancy Score: Relevancy Score: 999
Dewan D M - - 1982
The pH and volume of gastric contents from thirty-three patients undergoing elective caesarean section with thiopentone, nitrous oxide, succinylcholine anaesthesia were examined. Twenty patients received Gelusil 30 ml by mouth and thirteen patients received 30 ml of a 0.15 molar solution of sodium citrate. Following tracheal intubation, gastric fluid was ...
Relevancy Score: Relevancy Score: 944
Bezuidenhout D J - - 1984
Eighty-eight patients with endoscopically proven gastric and duodenal ulceration were treated with ranitidine ( Zantac ; Glaxo) or an antacid preparation containing aluminium hydroxide and magnesium trisilicate ( Gelusil ; Warner) over a 4-week period to assess healing. Clinical, haematological and biochemical assessment and endoscopy were performed at the beginning ...
Relevancy Score: Relevancy Score: 927
Knadler M P - - 1987
The absolute and relative bioavailability of nizatidine, an H2-blocker, was studied in healthy male volunteers. The absolute oral bioavailability, relative to that after intravenous administration, was 98% +/- 14%. The bioavailability of single and multiple oral doses of 150 mg nizatidine was unaffected by concurrent food ingestion; nizatidine may be ...
Relevancy Score: Relevancy Score: 901
Abboud T K - - 1984
We studied 33 women scheduled to undergo general anesthesia for cesarean section. Prior to induction of anesthesia, each patient received in a random fashion one of two prophylactic antacids. Group I (n = 17) received 30 ml Gelusil orally and Group II (n = 16) received 30 ml of 0.3 ...
Relevancy Score: Relevancy Score: 873
Metz D C - - 2003
To compare the safety and efficacy of pantoprazole with ranitidine for the maintenance of endoscopically documented healed (grade 0 or 1) erosive oesophagitis. Patients (371) were randomly assigned to receive pantoprazole 10, 20 or 40 mg or ranitidine 150 mg. Endoscopies were performed after 1, 3, 6 and 12 months ...
Relevancy Score: Relevancy Score: 815
Muruganathan Gandhimathi - - 2011
Moxifloxacin and lomefloxacin are fluoroquinolone antibiotics used in treating urinary and respiratory tract infections. Fluoroquinolones are known to have interactions with drugs that are active in gastro intestinal tract. Being moxifloxacin and lomefloxacin fluoroquinolones the interaction study of was carried out with sucralfate, gelusil, erythromycin and multi minerals. The interaction ...
Relevancy Score: Relevancy Score: 799
ChakĊ­rski I - - 1987
Two new antacid combinations--Ulsan and Ulsan D with high acid-neutralizing properties, produced by original Bulgarian techniques are presented. They exceed in acid-binding and acid-reducing properties the drugs now in use: Antiacid, Neutracid, Almagel, Alcid V, Maaloxan, Gelusil-Lac.
Relevancy Score: Relevancy Score: 758
Marks I N - - 1987
One hundred and thirty-two patients with endoscopically confirmed duodenal ulcers were entered into a 4-6-week double-blind trial of famotidine (Fm) and ranitidine (Rn). Seventy patients were randomised to Fm 40 mg at night and Rn placebo and 62 to Rn 300 mg at night and Fm placebo. Gelusil tablets were ...
Relevancy Score: Relevancy Score: 750
Turner P V - - 2000
BACKGROUND AND PURPOSE: Nonsteroidal anti-inflammatory drugs (NSAIDs) induce gastroduodenal injury and ulceration. The pathogenesis is uncertain, although reductions in cytoprotective prostaglandins and nitric oxide (NO) have been proposed. The effects of several cytoprotective agents on inhibition of gastroduodenal ulcerogenesis induced by CI-987, a novel NSAID, were evaluated in Wistar rats. ...
Relevancy Score: Relevancy Score: 727
Hagos B - - 1989
Eight brands of antacid tablets commonly available in the private market in Kenya were subjected to in-vitro tests for neutralizing capacity. The neutralizing capacity per gram and per tablet of the products was compared. The neutralizing capacity in millilitres of 0.1 M HC1 per gram ranged from 103.10 for Gelusil ...
Relevancy Score: Relevancy Score: 679
Millette C H - - 1981
A case of acute renal failure apparently caused by ingestion of large amounts of a magnesium-containing antacid is reported. A 51-year-old man was hospitalized with complete anuria and an associated hyperkalemia and hypermagnesemia. He had been taking 25-30 magnesium trisilicate-aluminum hydroxide (Gelusil) tablets daily for several years to relieve symptoms ...
Relevancy Score: Relevancy Score: 679
Channa A B - - 1985
281 patients, divided into two groups, were given single 30 ml dose of five different conventional oral antacids (sodium citrate, 0.3 M Maalox, Gelusil, Alludrox and Mucaine), separately and in combination with Cimetidine to study their effect on decreasing the acidity of stomach contents. In 181 patients receiving varying types ...
Relevancy Score: Relevancy Score: 679
BECK I T - - 1964
Fifteen cases of intractable chronic esophagitis due to gastroesophageal reflux were treated with a continuous intraesophageal antacid drip. A proprietary antacid preparation, Gelusil or monalium hydrate (Riopan), in a concentration of one part of antacid to nine parts of water, was infused into the mid-esophagus through a polyethylene tube with ...
Relevancy Score: Relevancy Score: 679
Cloud M L - - 1992
In a randomized, multicenter trial, nizatidine 150 mg or 300 mg, or placebo, was administered twice daily for six weeks to 515 patients with gastroesophageal reflux disease (GERD). Gelusil antacid tablets were taken as needed for pain. Significantly superior rates of endoscopically proven complete healing (normal-appearing mucosa) versus placebo occurred ...
Relevancy Score: Relevancy Score: 665
Barza M - - 1975
Four tetracyclines were studied in dogs to determine the relation between their lipophilicity and various other pharmacological characteristics. Lipid solubility correlated inversely with the mean concentration of drug in arterial plasma and renal uptake and excretion, and directly with the biliary concentration gradient (level in bile/level of free drug in ...
Relevancy Score: Relevancy Score: 620
MacCara M E - - 1985
A study was designed to determine the acid neutralization capacities (ANCs) of the new Canadian antacid formulations and to compare these products with standard antacid products in terms of lot-to-lot consistency, ANC, sodium and "calorie" contents, and price to the pharmacist. Twenty-three liquid and 18 tablet antacids were tested. The ...
Relevancy Score: Relevancy Score: 612
Gitlin N - - 1987
The efficacy and safety of famotidine, a potent new long-acting H2-receptor antagonist, was compared with placebo in a multicenter, double-blind, randomized, placebo-controlled study in the United States. A total of 384 patients with endoscopically proven acute duodenal ulcer disease were enrolled. Patients received either famotidine or a placebo. The patients ...
Relevancy Score: Relevancy Score: 592
Revicki D A - - 1998
BACKGROUND: Gastroesophageal reflux disease (GERD) affects health-related quality of life. METHODS: We enrolled 533 adults with a history of heartburn symptoms for at least 6 months of moderate to severe heartburn in 4 of the 7 days before study entry. Patients were treated with ranitidine 150 mg twice a day ...
Relevancy Score: Relevancy Score: 592
Shastri R A - - 1985
The effect of an antacid on the absorption of aspirin can vary depending on certain physical characteristics of the brand of aspirin chosen. In a study carried out to test the effect of a commonly used antacid on the absorption of a brand of aspirin, no differences were seen in ...
Relevancy Score: Relevancy Score: 240
Pace F - - 1985
In a multi-centre double-blind (double-dummy) trial the effectiveness of low-dose antacid gel (6 X 12 ml/d; neutralisation capacity 120 mmol) was compared with that of a standard dose of cimetidine (1 g/d) in the curative treatment of gastric ulcer. Antacid gel was given to 65 patients, cimetidine to 60. Diagnosis ...
Relevancy Score: Relevancy Score: 220
Arora A - - 1991
Twenty-five patients with bleeding peptic ulcers were randomized to receive either ranitidine 50 mg 8 hourly i.v. (control group) or a continuous nasogastric antacid infusion at the rate of 0.5 ml/min along with an i.v. injection of cimetidine 100 mg/h (treatment group). Twelve patients were included in the control group ...
Relevancy Score: Relevancy Score: 220
Lu Maggie - - 2007
The pathogenesis of patient dissatisfaction following involuntary therapeutic substitutions involving proton pump inhibitors (PPIs) is poorly understood. The aim of this study was to describe the patient population experiencing therapeutic failure and investigate whether failure was related to individual differences in response to the different PPIs. Treatment failures in a ...
Relevancy Score: Relevancy Score: 220
Hotz J - - 1994
BACKGROUND: It is generally accepted that functional dyspepsia is caused by heterogeneous pathogenetic factors. From the clinical point of view acid-related symptoms as heartburn, acid regurgitation and epigastric pain (acid-type) can be separated from general dyspeptic symptoms as predominant fullness, nausea/vomiting (dysmotility-type). PATIENTS AND METHODS: In the present study, the ...
Relevancy Score: Relevancy Score: 220
Pratha Vijaya - - 2006
We sought to evaluate safety and efficacy of IV pantoprazole when used as initial therapy in patients with gastroesophageal reflux disease (GERD) and a history of erosive esophagitis (EE) in a double-blind, placebo-controlled, randomized, parallel-group study. Patients were randomized to 7 days of once-daily IV or oral pantoprazole (40 mg) ...
Relevancy Score: Relevancy Score: 220
Joshi J V - - 1986
The bioavailability of contraceptive steroids was studied in 12 women who were given an antacid and a contraceptive pill simultaneously. They were given a single pill containing ethinyl estradiol (EE2) 30 micrograms in combination with either norethisterone (NET) acetate 1 mg (n = 6), or levonorgestrel (LNg) 150 micrograms, (n ...
Relevancy Score: Relevancy Score: 194
Kumar Shefalika S Department of Pharmacology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, - - 2014
The study aims to evaluate the management, maternal-fetal outcomes, and prescription behavior among inpatients with severe preeclampsia and eclampsia. This prospective cohort study in a tertiary referral center was conducted in 164 inpatient pregnant women who fulfilled the inclusion criteria. The study was conducted between November 2005 and February 2007. ...
Relevancy Score: Relevancy Score: 102
Kovacs Thomas O - - 2009
In a phase III study of lansoprazole treatment, patients with healed or unhealed erosive esophagitis entered a titrated open-label treatment period and received lansoprazole for <or=6 years to assess long-term maintenance therapy. Doses were adjusted depending on symptom response. Endoscopy was performed yearly. One hundred ninety-five subjects received lansoprazole for ...
Relevancy Score: Relevancy Score: 62
Kovacs Thomas O - - 2010
Gastroesophageal reflux disease (GERD) is a chronic symptomatic condition and may be associated with erosive esophagitis (EE). Considerable data on the long-term maintenance of healing of EE are available, but data on long-term GERD symptom prevention and patient quality of life (QOL) are limited. To investigate QOL in subjects with ...
Relevancy Score: Relevancy Score: 44
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