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Salunke Gayatri R GR Institute of Bioinformatics and Biotechnology, University of Pune, - - 2014
Nanoparticles (NPs) have gained significance in medical fields due to their high surface-area-to-volume ratio. In this study, we synthesized NPs from a medicinally important plant - Plumbago zeylanica. Aqueous root extract of P. zeylanica (PZRE) was analyzed for the presence of flavonoids, sugars, and organic acids using high-performance thin-layer chromatography ...
Zhang Kai K School of Medical Science & Griffith Health Institute, Gold Coast Campus, Griffith University, Southport, QLD 4222, Australia. - - 2014
Layered Double Hydroxides (LDHs)-based drug delivery systems have, for many years, shown great promises for the delivery of chemical therapeutics and bioactive molecules to mammalian cells in vitro and in vivo. This system offers high efficiency and drug loading density, as well as excellent protection of loaded molecules from undesired ...
Lebedev Mikhail A MA Department of Neurobiology, Center for Neuroengineering, Duke University Durham, NC, - - 2014
Hunter Larry W LW Department of Surgery, Mayo Clinic, Rochester, MN, - - 2014
Nano-sized complexes of calcium phosphate mineral and proteins (calcifying nanoparticles [CNPs]) serve as mineral chaperones. Thus, CNPs may be both a result and cause of soft tissue calcification processes. This study determined if CNPs could augment calcification of arterial vascular smooth muscle cells in vitro. CNPs 210 nm in diameter ...
Abraham Celeste M CM Texas A and M University Health Science Center, Baylor College of Dentistry, Department of Periodontics, 3302 Gaston Avenue, Room 142, Dallas, Texas, - - 2014
This review highlights a brief, chronological sequence of the history of dental implants. This historical perspective begins with ancient civilizations and spotlights predominant dentists and their contributions to implant development through time. The physical, chemical and biologic properties of various dental implant surfaces and coatings are discussed, and specific surface ...
Yang Hee-Seok HS Department of Occupational & Environmental Medicine, College of Medicine, Dong-A University, Busan, - - 2014
We reported a case of complicated silicosis that occurred in a glass manufacturing plant worker who had presumably been exposed to low-concentration free silica for almost 20 years. To the best of our knowledge this report is the first in the Republic of Korea. The physician's first impression was cancer since ...
Manke Amruta A Department of Pharmaceutical Sciences, West Virginia University, 1, Medical Center Drive, Morgantown, WV 26506, USA. - - 2014
Given their extremely small size and light weight, carbon nanotubes (CNTs) can be readily inhaled by human lungs resulting in increased rates of pulmonary disorders, particularly fibrosis. Although the fibrogenic potential of CNTs is well established, there is a lack of consensus regarding the contribution of physicochemical attributes of CNTs ...
Campbell Jacob J Developmental Neuroscience, Munroe-Meyer Institute, University of Nebraska Medical Center Omaha, NE, - - 2014
Synaptic activity is intimately linked to neuronal structure and function. Stimulation of live cultured primary neurons, coupled with fluorescent indicator imaging, is a powerful technique to assess the impact of synaptic activity on neuronal protein trafficking and function. Current technology for neuronal stimulation in culture include chemical techniques or microelectrode ...
Liu Yu Y National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, China. - - 2014
Polyethylenimine (PEI) has attracted much attention as a DNA condenser, but its toxicity and non-specific targeting limit its potential. To overcome these limitations, Antheraea pernyi silk fibroin (ASF), a natural protein rich in arginyl-glycyl-aspartic acid (RGD) peptides that contains negative surface charges in a neutral aqueous solution, was used to ...
Niu Yunfei Y Department of Orthopedic Surgery, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of - - 2014
Mesoporous magnesium silicate (m-MS) and poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) (PCL-PEG-PCL) composite (m-MPC) was synthesized by solvent casting method. The results suggest that the mechanical properties of compressive strength and elastic modulus, as well as hydrophilicity, of the m-MPC increased with increase of m-MS content in the composites. In addition, the weight loss ...
Sharp Thomas T School of Computer Science, The University of Manchester Manchester, UK ; Laboratory for Neural Circuit Theory, RIKEN Brain Science Institute, Wakoshi Saitama, - - 2014
Simulations of neural circuits are bounded in scale and speed by available computing resources, and particularly by the differences in parallelism and communication patterns between the brain and high-performance computers. SpiNNaker is a computer architecture designed to address this problem by emulating the structure and function of neural tissue, using ...
Li Yan Y MOE Key Laboratory of Pollution Processes and Environmental Criteria, College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China. - - 2014
Trichloroethylene (TCE) is a common groundwater contaminant of toxic and carcinogenic concern. Aerobic co-metabolic processes are the predominant pathways for TCE complete degradation. In this study, Pseudomonas fluorescens was studied as the active microorganism to degrade TCE under aerobic condition by co-metabolic degradation using phenol and gasoline as growth substrates. ...
Cichon Nicole B NB Developmental Neurophysiology, Neuroanatomy, University Medical Center Hamburg-Eppendorf Hamburg, - - 2014
Flexible communication within the brain, which relies on oscillatory activity, is not confined to adult neuronal networks. Experimental evidence has documented the presence of discontinuous patterns of oscillatory activity already during early development. Their highly variable spatial and time-frequency organization has been related to region specificity. However, it might be ...
Yamamoto Takanobu T Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, New Jersey, United States of - - 2014
Nicotinamide phosphoribosyltransferase (Nampt), the rate-limiting enzyme for nicotinamide adenine dinucleotide (NAD+) synthesis, and Sirt1, an NAD+-dependent histone deacetylase, protect the heart against ischemia/reperfusion (I/R). It remains unknown whether Nampt mediates the protective effect of ischemic preconditioning (IPC), whether nicotinamide mononucleotide (NMN, 500 mg/kg), a product of Nampt in the NAD+ ...
Jansson Keith H KH Laboratory for Cancer Ontogeny and Therapeutics, Department of Biological Sciences, University of Delaware, Newark, Delaware, United States of America; The Center for Translational Cancer Research, University of Delaware, Newark, Delaware, United States of - - 2014
Prostate cancer (PCa) is believed to metastasize through the blood/lymphatics systems; however, PCa may utilize the extensive innervation of the prostate for glandular egress. The interaction of PCa and its nerve fibers is observed in 80% of PCa and is termed perineural invasion (PNI). PCa cells have been observed traveling ...
Pelletier Amandine A PériTox Laboratory, UMR-I 01 INERIS, Faculty of Medicine, Jules Verne University of Picardy, Amiens, - - 2014
Some studies have shown that people living near a mobile phone base station may report sleep disturbances and discomfort. Using a rat model, we have previously shown that chronic exposure to a low-intensity radiofrequency electromagnetic field (RF-EMF) was associated with paradoxical sleep (PS) fragmentation and greater vasomotor tone in the ...
Kim Baek Hyun BH Department of Electrical and Computer Engineering, University of Missouri, Columbia, MO 65211, United - - 2014
The field of conventional energy conversion using radioisotopes has almost exclusively focused on solid-state materials. Herein, we demonstrate that liquids can be an excellent media for effective energy conversion from radioisotopes. We also show that free radicals in liquid, which are continuously generated by beta radiation, can be utilized for ...
Everett J J Institute for Science and Technology in Medicine, Keele University, , Stoke-on-Trent, Staffordshire ST4 7QB, - - 2014
For decades, a link between increased levels of iron and areas of Alzheimer's disease (AD) pathology has been recognized, including AD lesions comprised of the peptide β-amyloid (Aβ). Despite many observations of this association, the relationship between Aβ and iron is poorly understood. Using X-ray microspectroscopy, X-ray absorption spectroscopy, electron ...
Khara Pratick P Department of Microbiology, Bose Institute, P-1/12 C.I.T. Scheme VII M, Kolkata 700054, - - 2014
Sphingobium sp. PNB, like other sphingomonads, has multiple ring-hydroxylating oxygenase (RHO) genes. Three different fosmid clones have been sequenced to identify the putative genes responsible for the degradation of various aromatics in this bacterial strain. Comparison of the map of the catabolic genes with that of different sphingomonads revealed a ...
Sun Guo-Xiang GX School of Chemical and Biological Engineering, Yancheng Institute of Technology, Yancheng 224051, China. - - 2014
In order to investigate the biological activity of novel 1,2,4-triazole compounds, seventeen novel 1,2,4-triazole derivatives containing pyridine moiety were synthesized under microwave assistant condition by multi-step reactions. The structures were characterized by 1H NMR, MS and elemental analyses. The target compounds were evaluated for their fungicidal activities against Stemphylium lycopersici ...
Saiki Akiko A Brain Science Institute, Tamagawa University, Machida, Tokyo, Japan; Graduate School of Brain Sciences, Tamagawa University, Machida, Tokyo, Japan; JST CREST, Chiyoda-ku, Tokyo, - - 2014
Rodents have primary and secondary motor cortices that are involved in the execution of voluntary movements via their direct and parallel projections to the spinal cord. However, it is unclear whether the rodent secondary motor cortex has any motor function distinct from the primary motor cortex to properly control voluntary ...
Daphu Inderjit I NorLux Neuro-Oncology Laboratory, Department of Biomedicine, University of Bergen, 5009 Bergen, Norway. - - 2014
Malignant melanoma is the most lethal form of skin cancer, with a high propensity to metastasize to the brain. More than 60% of melanomas have the BRAFV600E mutation, which activates the mitogen-activated protein kinase (MAPK) pathway [1]. In addition, increased PI3K (phosphoinositide 3-kinase) pathway activity has been demonstrated, through the ...
Thangapazham Rajesh L RL Department of Dermatology, Uniformed Services University of the Health Sciences, Bethesda, MD 20851, USA. - - 2014
Dermal fibroblasts are mesenchymal cells found between the skin epidermis and subcutaneous tissue. They are primarily responsible for synthesizing collagen and glycosaminoglycans; components of extracellular matrix supporting the structural integrity of the skin. Dermal fibroblasts play a pivotal role in cutaneous wound healing and skin repair. Preclinical studies suggest wider ...
Pupo Yasmine M YM Postgraduate Program in Dentistry, Department of Dentistry, State University of Ponta Grossa, Paraná 84030-900, Brazil. - - 2014
This study investigated the resin-dentin bond strength (μTBS), degree of conversion (DC), and antibacterial potential of an innovative adhesive system containing a quaternary ammonium methacrylate polymer (QAMP) using in situ and in vitro assays. Forty-two human third molars were flattened until the dentin was exposed and were randomly distributed into ...
Rozynek Zbigniew Z 1] Department of Physics, Norwegian University of Science and Technology, Hoegskoleringen 5, N-7491 Trondheim, Norway [2] Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, - - 2014
Janus and patchy particles have designed heterogeneous surfaces that consist of two or several patches with different materials properties. These particles are emerging as building blocks for a new class of soft matter and functional materials. Here we introduce a route for forming heterogeneous capsules by producing highly ordered jammed ...
Born Dennis-Peter DP Department of Sport Science, University of Wuppertal, Fuhlrottstraße 10, 42119 Wuppertal, Germany ; Department of Sport Sciences, Integrative and Experimental Exercise Science, University of Würzburg, 97082 Würzburg, - - 2014
Repeated sprint performance is determined by explosive production of power, as well as rapid recovery between successive sprints, and there is evidence that compression garments and sports taping can improve both of these factors. In each of two sub-studies, female athletes performed two sets of 30 30-m sprints (one sprint ...
Rinaldi Wilson W Department of Physical Education, State University of Maringá, Maringá, PR, - - 2014
Postnatal early overfeeding and physical inactivity are serious risk factors for obesity. Physical activity enhances energy expenditure and consumes fat stocks, thereby decreasing body weight (bw). This study aimed to examine whether low-intensity and moderate exercise training in different post-weaning stages of life is capable of modulating the autonomic nervous ...
Chen Chang C Shanghai Engineering Research Center of Ultra-Precision Optical Manufacturing, Department of Optical Science and Engineering, Fudan University, Shanghai 200433, - - 2014
In fabrication of nano- and quantum devices, it is sometimes critical to position individual dopants at certain sites precisely to obtain the specific or enhanced functionalities. With first-principles simulations, we propose a method for substitutional doping of individual atom at a certain position on a stepped metal surface by single-atom ...
Choi Won Jin WJ Advanced Materials Division, Korea Research Institute of Chemical Technology (KRICT) Daejeon, 305-343, South - - 2014
Controlling the orientations of nanomaterials on arbitrary substrates is crucial for the development of practical applications based on such materials. The aligned epitaxial growth of single-walled carbon nanotubes (SWNTs) on specific crystallographic planes in single crystalline sapphire or quartz has been demonstrated; however, these substrates are unsuitable for large scale ...
Sweetman A M AM 1] School of Physics & Astronomy, University of Nottingham, Nottingham NG7 2RD, UK - - 2014
Hydrogen bonding underpins the properties of a vast array of systems spanning a wide variety of scientific fields. From the elegance of base pair interactions in DNA to the symmetry of extended supramolecular assemblies, hydrogen bonds play an essential role in directing intermolecular forces. Yet fundamental aspects of the hydrogen ...
Chaudhari Nitin Kaduba NK Department of Advanced Materials Chemistry, Korea University, 2511 Sejong-ro, Sejong 339-700, Republic of - - 2014
Human urine, otherwise potentially polluting waste, is an universal unused resource in organic form disposed by the human body. We present for the first time "proof of concept" of a convenient, perhaps economically beneficial, and innovative template-free route to synthesize highly porous carbon containing heteroatoms such as N, S, Si, ...
Moslehifard Elnaz E Assistant Professor, Department of Prosthodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, - - 2014
This clinical report describes a treatment option for replacement of a missing mandibular anterior tooth using InCeram resin bonded fixed partial denture (RBFPD). The conventional approach for replacing mandibular incisors dictates the placement of either a conventional porcelain-fused-to-metal (PFM) bridge, Maryland bridge, or fiber-reinforced composite veneer bridge and several appearance-related ...
Deogade Suryakant Chhagan SC Department of Prosthodontics, Hitkarini Dental College & Hospital, Jabalpur, Madhya Pradesh, - - 2014
This clinical report describes a technique to improve support for sunken cheeks using magnet retained detachable acrylic cheek plumpers. The new generation of magnets with improved technology provides sufficient denture retention for clinical application. However, further follow-up may be necessary to ascertain the long-term usefulness of the magnet-retained prosthesis, because ...
Carey Joanna C JC Department of Earth and Environment, Boston University Boston, MA, - - 2014
Silicon (Si) plays a critical role in plant functional ecology, protecting plants from multiple environmental stressors. While all terrestrial plants contain some Si, wetland grasses are frequently found to have the highest concentrations, although the mechanisms driving Si accumulation in wetland grasses remain in large part uncertain. For example, active ...
Erickson Laura C LC Department of Neuroscience, Georgetown University Medical Center, Washington DC, USA ; Department of Neurology, Georgetown University Medical Center, Washington DC, - - 2014
Audiovisual (AV) speech integration is often studied using the McGurk effect, where the combination of specific incongruent auditory and visual speech cues produces the perception of a third illusory speech percept. Recently, several studies have implicated the posterior superior temporal sulcus (pSTS) in the McGurk effect; however, the exact roles ...
Martin Stéphanie S Helen Wills Neuroscience Institute, University of California Berkeley, CA, USA ; Department of Bioengineering, École Polytechnique Fédérale de Lausanne Lausanne, - - 2014
Auditory perception and auditory imagery have been shown to activate overlapping brain regions. We hypothesized that these phenomena also share a common underlying neural representation. To assess this, we used electrocorticography intracranial recordings from epileptic patients performing an out loud or a silent reading task. In these tasks, short stories ...
Xiao Ting T Department of Electronic Engineering, Chinese University of Hong Kong, New Territories, Hong - - 2014
The interpenetrating morphology formed by the electron donor and acceptor materials is critical for the performance of polymer:fullerene bulk heterojunction (BHJ) photovoltaic (PV) cells. In this work we carried out a systematic investigation on a high PV efficiency (>6%) BHJ system consisting of a newly developed 5,6-difluorobenzo[c] thiadiazole-based copolymer, PFBT-T20TT, ...
Wang Zesong Z Key Laboratory of Artificial Micro- and Nano-Materials of Ministry of Education of China, School of Physics and Technology, Wuhan University, Wuhan 430072, - - 2014
Based on the extensive application of 2 × 1.7MV Tandetron accelerator, a low-energy cluster chamber has been built to explore for synthesizing graphene. Raman spectrum and atomic force microscopy (AFM) show that an amorphous carbon film in nanometer was deposited on the silicon by C4 cluster implantation. And we replaced the substrate ...
Consonni Vincent V Univ. Grenoble Alpes, LMGP, Grenoble F-38000, France ; CNRS, LMGP, Grenoble F-38000, - - 2014
CdTe is an important compound semiconductor for solar cells, and its use in nanowire-based heterostructures may become a critical requirement, owing to the potential scarcity of tellurium. The effects of the CdCl2 heat treatment are investigated on the physical properties of vertically aligned ZnO/CdTe core-shell nanowire arrays grown by combining ...
Husen Azamal A Department of Biology, College of Natural and Computational Sciences, University of Gondar, P.O. Box 196, Gondar, - - 2014
Nanotechnology is an exciting and powerful discipline of science; the altered properties of which have offered many new and profitable products and applications. Agriculture, food and medicine sector industries have been investing more in nanotechnology research. Plants or their extracts provide a biological synthesis route of several metallic nanoparticles which ...
Segura Rodrigo A RA Instituto de Química y Bioquímica, Facultad de Ciencias, Universidad de Valparaíso, Av. Gran Bretaña 1111, Valparaíso 2340000, - - 2014
The hybrid structures composed of gold nanoparticles and carbon nanotubes were prepared using porous alumina membranes as templates. Carbon nanotubes were synthesized inside the pores of these templates by the non-catalytic decomposition of acetylene. The inner cavity of the supported tubes was used as nanoreactors to grow gold particles by ...
Li Shaoyuan S State Key Laboratory of Complex Nonferrous Metal Resources Clear Utilization/Silicon Metallurgy and Silicon Material Engineering Research Center of Universities in Yunnan Province, Kunming 650093, China ; Faculty of Metallurgical and Energy Engineering, Kunming University of Science and Technology, Kunming 650093, - - 2014
In this paper, the moderately and lightly doped porous silicon nanowires (PSiNWs) were fabricated by the 'one-pot procedure' metal-assisted chemical etching (MACE) method in the HF/H2O2/AgNO3 system at room temperature. The effects of H2O2 concentration on the nanostructure of silicon nanowires (SiNWs) were investigated. The experimental results indicate that porous ...
Trauth Stephanie S Zentrum für Molekulare Biologie der Universität Heidelberg (ZMBH), Heidelberg, Germany; Center for Quantitative Analysis of Molecular and Cellular Biosystems (BioQuant), University of Heidelberg, Heidelberg, - - 2014
Fluorescent protein promoter reporters are important tools that are widely used for diverse purposes in microbiology, systems biology and synthetic biology and considerable engineering efforts are still geared at improving the sensitivity of the reporter systems. Here we focus on dark noise, i.e. the signal that is generated by the ...
Brown Mark S MS Electrical and Electronic Engineering, UCL, London, United - - 2014
The uncertainty in time of particle detection within a scintillator detector, characterised by the coinci- dence time resolution (CTR), is explored with respect to the interaction position within the scintillator crystal itself. Electronic collimation between two scintillator detectors is utilised to determine the CTR with depth of interaction (DOI) for ...
de Andrade Moura Laura L Departamento de Biologia Molecular e Celular, Instituto de Biologia, Universidade Federal Fluminense, Outeiro de São João Batista, s/n, Centro, Niterói, 24020-141, RJ, Brazil. - - 2014
Cardiovascular diseases represent a major cause of disability and death worldwide. Therapeutics are available, but they often have unsatisfactory results and may produce side effects. Alternative treatments based on the use of natural products have been extensively investigated, because of their low toxicity and side effects. Marine organisms are prime ...
Wartolowska Karolina K National Institute of Health Research Musculoskeletal Biomedical Research Unit, Oxford, UK Botnar Institute of Musculoskeletal Sciences, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford OX3 7LD, UK - - 2014
To investigate whether placebo controls should be used in the evaluation of surgical interventions. Systematic review. We searched Medline, Embase, and the Cochrane Controlled Trials Register from their inception to November 2013. Randomised clinical trials comparing any surgical intervention with placebo. Surgery was defined as any procedure that both changes ...
Moyo Francis F Division of Pharmaceutical Chemistry, Faculty of Pharmacy, Rhodes University, P.O. Box 94, Grahamstown 6140, South Africa. - - 2014
Renewed focus on the sorption of hydrophobic organic chemicals (HOCs) onto mineral surfaces and soil components is required due to the increased and wider range of organic pollutants being released into the environment. This mini-review examines the possibility of the contribution and mechanism of HOC sorption onto clay mineral sorbents ...
Streicher Wolfgang W Department of Urology, Ulm University, Ulm, - - 2014
Advanced castration resistant prostate cancer (CRPC) is often characterized by an increase of C-terminally truncated, constitutively active androgen receptor (AR) variants. Due to the absence of a ligand binding domain located in the AR-C-terminus, these receptor variants (also termed ARΔLBD) are unable to respond to all classical forms of endocrine ...
Spyropoulou Eleni A - - 2014
Glandular trichomes are production and storage organs of specialized metabolites such as terpenes, which play a role in the plant's defense system. The present study aimed to shed light on the regulation of terpene biosynthesis in Solanum lycopersicum trichomes by identification of transcription factors (TFs) that control the expression of ...
Gew Lai Ti LT Department of Biological Sciences, Faculty of Science and Technology, Sunway University, No. 5, Jalan Universiti, Bandar Sunway, Petaling Jaya, Selangor 46150, Malaysia ; Department of Chemistry, Faculty of Science, University of Malaya, Kuala Lumpur 50603, - - 2014
The fluid mosaic model of Singer and Nicolson in 1972 shows how proteins are embedded in membranes. To elucidate the interactions between proteins and the surrounding lipids, stearic acid (SA) and bovine serum albumin (BSA) were used as lipid-protein components to mimic the normal membrane bilayer environment using the Langmuir-Blodgett ...
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