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Gereli Arel A Department of Orthopedics and Traumatology, Ac─▒badem University, Faculty of Medicine, ─░stanbul, Turkey. - - 2014
Objective: The aim of this study was to assess the efficacy of a soluble absorbable silicon compound on healing of the Achilles tendon. Methods: The Achilles tendons of 21 Wistar albino rats were cut and repaired. A 0.01 ml organic silicon solution (silanol) was injected peri/intratendinously into the left leg ...
Ochedowski Oliver O Fakultät für Physik and CENIDE, Universität Duisburg-Essen, 47048 Duisburg, - - 2014
The controlled creation of defects in silicon carbide represents a major challenge. A well-known and efficient tool for defect creation in dielectric materials is the irradiation with swift (Ekin≥500 keV/amu) heavy ions, which deposit a significant amount of their kinetic energy into the electronic system. However, in the case of silicon ...
Lee Michael M Institut de Sciences Analytiques (ISA) - UMR 5280, Université de Lyon, 5 rue de la Doua, 69100, Villeurbanne, France, - - 2014
Immunosensors based on electrolyte-oxide-semiconductors (EOS) have been extensively researched over the last few decades. By electrochemical impedance spectroscopy (EIS) the specific molecular biorecognition of the antibody-antigen (Ab-Ag) can be detected providing an alternative quantitative system to immunoassay techniques. The electrochemical variations from a fabricated immunosensor can provide quantitative values for ...
Han W M WM Biomedical Engineering, University of Delaware, 125 E. Delaware Ave., Newark, DE 19716, - - 2014
Mechanical signals regulate a multitude of cell functions and ultimately govern fibrous tissue growth, maintenance and repair. Such mechanotransduction processes often involve modulation of intracellular calcium concentration ([Ca2+]i). However, most studies interrogate these responses in cells in simplified culture systems, thereby removing potentially important inputs from the native extracellular microenvironment. ...
Rofkar Jordan R - - 2014
Here we report on the analysis of two aquatic plant species, Azolla caroliniana and Lemna minor, with respect to tolerance and uptake of co-occurring arsenic, copper, and silicon for use in engineered wetlands. Plants were cultured in nutrient solution that was amended with arsenic (0 or 20 microM), copper (2 ...
Chen Wanghua W LPICM, CNRS, Ecole Polytechnique, Palaiseau 91128, - - 2014
The incorporation of metal atoms into silicon nanowires during metal-particle-assisted growth is a critical issue for various nanowire-based applications. Here we have been able to access directly the incorporation and redistribution of metal atoms into silicon nanowires produced by two different processes at growth rates ranging from 3 to 40 nm s(-1), ...
Tang Tiantian T 1] School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, New York 11794, USA - - 2014
Marine particles transport organic matter through the water column to the sediment where the organic matter can be buried. This pathway is one of the few natural removal mechanisms of CO2 from the atmosphere over geological time. Picophytoplankton, major primary producers in the ocean, have until recently been thought unimportant ...
Villanueva Alex A Center for Energy Harvesting Materials and Systems (CEHMS), Bio-Inspired Materials and Devices Laboratory (BMDL), Department of Mechanical Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of - - 2014
The development of a rowing jellyfish biomimetic robot termed as "Robojelly", has led to the discovery of a passive flexible flap located between the flexion point and bell margin on the Aurelia aurita. A comparative analysis of biomimetic robots showed that the presence of a passive flexible flap results in ...
Theakston R David G RD Alistair Reid Venom Research Unit, Liverpool School of Tropical Medicine, University of Liverpool, Liverpool L3 5QA, UK. - - 2014
In many cases of envenoming following snake bite, the snake responsible for the accident remains unidentified; this frequently results in difficulty deciding which antivenom to administer to the systemically-envenomed victim, especially when only monospecific antivenoms are available. Normally the specific diagnosis of snake bite can be conveniently made using clinical ...
Shlyakhtenko Luda S LS Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska, United States of - - 2014
The APOBEC3 family of DNA cytosine deaminases functions to block the spread of endogenous retroelements and retroviruses including HIV-1. Potency varies among family members depending on the type of parasitic substrate. APOBEC3A (A3A) is unique among the human enzymes in that it is expressed predominantly in myeloid lineage cell types, ...
Hristu Radu R Center for Microscopy-Microanalysis and Information Processing, University Politehnica of Bucharest, 313 Splaiul Independentei, 060042 Bucharest, - - 2014
Silicon carbide is one of the most promising materials for power electronic devices capable of operating at extreme conditions. The widespread application of silicon carbide power devices is however limited by the presence of structural defects in silicon carbide epilayers. Our experiment demonstrates that optical second harmonic generation imaging represents ...
Kim Hyo Jin HJ 1] Icheon Branch, Korea Institute of Ceramic Engineering and Technology, Icheon, Republic of Korea [2] School of Advanced Materials Science and Engineering, Sungkyunkwan University, Suwon, Republic of - - 2014
It is of critical importance to improve toughness, strength, and wear-resistance together for the development of advanced structural materials. Herein, we report on the synthesis of unoxidized graphene/alumina composite materials having enhanced toughness, strength, and wear-resistance by a low-cost and environmentally benign pressure-less-sintering process. The wear resistance of the composites ...
Kim Bum-Su BS Department of Cogno-Mechatronics Engineering, Pusan National University, 1268-50, Samnangin-ro, Samnangjin-eup, Miryang 627-706, Republic of - - 2014
Hydrogen-treated ZnCoO shows magnetic behavior, which is related to the formation of Co-H-Co complexes. However, it is not well known how the complexes are connected to each other and with what directional behavior they are ordered. In this point of view, ZnCoO nanowire is an ideal system for the study ...
Haberle Simon G SG Department of Archaeology and Natural History, College of Asia and the Pacific, Australian National University, Canberra, Australian Capital Territory, - - 2014
The composition and relative abundance of airborne pollen in urban areas of Australia and New Zealand are strongly influenced by geographical location, climate and land use. There is mounting evidence that the diversity and quality of airborne pollen is substantially modified by climate change and land-use yet there are insufficient ...
Kubota Kaoru K Atmosphere and Ocean Research Institute (AORI), the University of Tokyo, 5-1-5 Kashiwa, Chiba 277-8564, - - 2014
While biogeochemical and physical processes in the Southern Ocean are thought to be central to atmospheric CO2 rise during the last deglaciation, the role of the equatorial Pacific, where the largest CO2 source exists at present, remains largely unconstrained. Here we present seawater pH and pCO2 variations from fossil Porites ...
Jang Hyun-June HJ Department of Electronic Materials Engineering, Kwangwoon University, 447-1, Wolgye-dong, Nowon-gu, Seoul 139-701, Republic of - - 2014
Recently, thin-film transistor based-ISFETs with the dual-gate (DG) structures have been proposed, in order to beat the Nernst response of the standard ISFET, utilizing diverse organic or inorganic materials. The immutable Nernst response can be dramatically transformed to an ultra-sensing margin, with the capacitive-coupling arisen from the DG structure. In ...
Katanosaka Yuki Y Department of Cardiovascular Physiology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Shikata-cho 2-5-1, Okayama city, Okayama 700-8558, - - 2014
The heart has a dynamic compensatory mechanism for haemodynamic stress. However, the molecular details of how mechanical forces are transduced in the heart are unclear. Here we show that the transient receptor potential, vanilloid family type 2 (TRPV2) cation channel is critical for the maintenance of cardiac structure and function. ...
Kingsley James W JW Ossila Ltd, Kroto Innovation Centre, Broad Lane, Sheffield, S3 7HQ, - - 2014
We have used Soxhlet solvent purification to fractionate a broad molecular weight distribution of the polycarbazole polymer PCDTBT into three lower polydispersity molecular weight fractions. Organic photovoltaic devices were made using a blend of the fullerene acceptor PC71BM with the molecular weight fractions. An average power conversion efficiency of 5.89% ...
Beesley David J DJ 1] Department of Physics, Imperial College London, Prince Consort Road, South Kensington, London SW7 2AZ, UK [2] Department of Chemistry, Imperial College London, Exhibition Road, South Kensington, London SW7 2AZ, UK - - 2014
Coplanar electrodes formed from asymmetric metals separated on the nanometre length scale are essential elements of nanoscale photonic and electronic devices. Existing fabrication methods typically involve electron-beam lithography-a technique that enables high fidelity patterning but suffers from significant limitations in terms of low throughput, poor scalability to large areas and ...
Cheng Boran B Department of Oncology, Zhongnan Hospital of Wuhan University, Hubei Key Laboratory of Tumor Biological Behaviors, Hubei Cancer Clinical Study Center, Wuhan, Hubei, People's Republic of - - 2014
Circulating tumor cells (CTCs) in the blood which have detached from both the primary tumor and any metastases may be considered as a "liquid biopsy" and are expected to replace tumor biopsies in the monitoring of treatment response and determining patient prognosis. Here, we introduce a facile and efficient CTC ...
Muck Simone S Department of Limnology and Oceanography, Center of Ecology, University of Vienna Vienna, - - 2014
We hypothesized that mixing zones of deep-water masses act as ecotones leading to alterations in microbial diversity and activity due to changes in the biogeochemical characteristics of these boundary systems. We determined the changes in prokaryotic and viral abundance and production in the Vema Fracture Zone (VFZ) of the subtropical ...
de Peppo Giuseppe Maria GM The New York Stem Cell Foundation Research Institute, New York, NY, USA ; Department of Biomaterials, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden ; BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy, University of Gothenburg, Göteborg, - - 2014
Patterning medical devices at the nanoscale level enables the manipulation of cell behavior and tissue regeneration, with topographic features recognized as playing a significant role in the osseointegration of implantable devices. In this study, we assessed the ability of titanium-coated hemisphere-like topographic nanostructures of different sizes (approximately 50, 100, and ...
Nobile Clarissa J CJ - - 2014
Biofilms are resilient, surface-associated communities of cells with specialized properties (e.g., resistance to drugs and mechanical forces) that are distinct from those of suspension (planktonic) cultures. Biofilm formation by the opportunistic human fungal pathogen Candida albicans is medically relevant because C. albicans infections are highly correlated with implanted medical devices, which ...
Lanter Bernard B BB Department of Biological Sciences, Binghamton University, Binghamton, New York, - - 2014
Atherosclerosis, a disease condition resulting from the buildup of fatty plaque deposits within arterial walls, is the major underlying cause of ischemia (restriction of the blood), leading to obstruction of peripheral arteries, congestive heart failure, heart attack, and stroke in humans. Emerging research indicates that factors including inflammation and infection ...
Nehoff Hayley H Department of Pharmacology and Toxicology, University of Otago, Dunedin, New - - 2014
The growing research interest in nanomedicine for the treatment of cancer and inflammatory-related pathologies is yielding encouraging results. Unfortunately, enthusiasm is tempered by the limited specificity of the enhanced permeability and retention effect. Factors such as lack of cellular specificity, low vascular density, and early release of active agents prior ...
de Boer W D A M WD Van der Waals-Zeeman Institute, University of Amsterdam, Science Park 904, 1098 XH Amsterdam, The - - 2014
We investigate photoluminescence of Eu-related emission in a GaN host consisting of thin layers grown by organometallic vapor-phase epitaxy. By comparing it with a reference sample of Eu-doped Y2O3, we find that the fraction of Eu(3+) ions that can emit light upon optical excitation is of the order of 1%. ...
Liu Ningning N 1] State Key Lab of Respiratory Disease, Protein Modification and Degradation Lab, Department of Pathophysiology, Guangzhou Medical University, Guangdong 510182, China [2] Guangzhou Research Institute of Cardiovascular Disease, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510260, People's Republic of China - - 2014
The successful development of bortezomib-based therapy for treatment of multiple myeloma has established proteasome inhibition as an effective therapeutic strategy, and both 20S proteasome peptidases and 19S deubiquitinases (DUBs) are becoming attractive targets of cancer therapy. It has been reported that metal complexes, such as copper complexes, inhibit tumor proteasome. ...
Zhang Shunhong S Center for Applied Physics and Technology, College of Engineering, Peking University, Beijing 100871, - - 2014
Design and synthesis of two-dimensional (2D) materials with robust ferromagnetism and biocompatibility is highly desirable due to their potential applications in spintronics and biodevices. However, the hotly pursued 2D sheets including pristine graphene, monolayer BN, and layered transition metal dichalcogenides are nonmagnetic or weakly magnetic. Using biomimetic particle swarm optimization ...
Watanabe Eiji E 1] Japan Agency for Marine-Earth Science and Technology, 3173-25 Showa-machi, Kanazawa-ku, Yokohama, Kanagawa 236-0001, Japan - - 2014
The future conditions of Arctic sea ice and marine ecosystems are of interest not only to climate scientists, but also to economic and governmental bodies. However, the lack of widespread, year-long biogeochemical observations remains an obstacle to understanding the complicated variability of the Arctic marine biological pump. Here we show ...
Lee Chia-Hui CH Department of Materials Science and Engineering, National Chiao Tung University, 1001 University Road, Hsinchu 300, - - 2014
Nanotopography modulates the physiological behavior of cells and cell-cell interactions, but the manner of communication remains unclear. Cell networking (syncytium) of astroglia provides the optimal microenvironment for communication of the nervous system. C6 glioma cells were seeded on nanodot arrays with dot diameters ranging from 10 to 200 nm. Cell viability, ...
Karavitaki Alexandra E AE Institute of Vision and Optics, University of Crete, Crete, - - 2014
Our purpose was to evaluate the long-term visual outcomes after bilateral implantation of Crystalens(®) HD (Bausch and Lomb, Inc.) accommodative intraocular lenses. In this study, 25 patients (50 eyes) who underwent cataract surgery and bilateral Crystalens HD accommodative intraocular lens implantation were included. The Crystalens HD lens was implanted in ...
Panneerselvam Suresh S Department of Molecular Science and Technology, Ajou University, Suwon 443-749, Korea. - - 2014
Nanotechnology has arisen as a key player in the field of nanomedicine. Although the use of engineered nanoparticles is rapidly increasing, safety assessment is also important for the beneficial use of new nanomaterials. Considering that the experimental assessment of new nanomaterials is costly and laborious, in silico approaches hold promise. ...
Salunke Gayatri R GR Institute of Bioinformatics and Biotechnology, University of Pune, - - 2014
Nanoparticles (NPs) have gained significance in medical fields due to their high surface-area-to-volume ratio. In this study, we synthesized NPs from a medicinally important plant - Plumbago zeylanica. Aqueous root extract of P. zeylanica (PZRE) was analyzed for the presence of flavonoids, sugars, and organic acids using high-performance thin-layer chromatography ...
Zhang Kai K School of Medical Science & Griffith Health Institute, Gold Coast Campus, Griffith University, Southport, QLD 4222, Australia. - - 2014
Layered Double Hydroxides (LDHs)-based drug delivery systems have, for many years, shown great promises for the delivery of chemical therapeutics and bioactive molecules to mammalian cells in vitro and in vivo. This system offers high efficiency and drug loading density, as well as excellent protection of loaded molecules from undesired ...
Lebedev Mikhail A MA Department of Neurobiology, Center for Neuroengineering, Duke University Durham, NC, - - 2014
Hunter Larry W LW Department of Surgery, Mayo Clinic, Rochester, MN, - - 2014
Nano-sized complexes of calcium phosphate mineral and proteins (calcifying nanoparticles [CNPs]) serve as mineral chaperones. Thus, CNPs may be both a result and cause of soft tissue calcification processes. This study determined if CNPs could augment calcification of arterial vascular smooth muscle cells in vitro. CNPs 210 nm in diameter ...
Abraham Celeste M CM Texas A and M University Health Science Center, Baylor College of Dentistry, Department of Periodontics, 3302 Gaston Avenue, Room 142, Dallas, Texas, - - 2014
This review highlights a brief, chronological sequence of the history of dental implants. This historical perspective begins with ancient civilizations and spotlights predominant dentists and their contributions to implant development through time. The physical, chemical and biologic properties of various dental implant surfaces and coatings are discussed, and specific surface ...
Yang Hee-Seok HS Department of Occupational & Environmental Medicine, College of Medicine, Dong-A University, Busan, - - 2014
We reported a case of complicated silicosis that occurred in a glass manufacturing plant worker who had presumably been exposed to low-concentration free silica for almost 20 years. To the best of our knowledge this report is the first in the Republic of Korea. The physician's first impression was cancer since ...
Manke Amruta A Department of Pharmaceutical Sciences, West Virginia University, 1, Medical Center Drive, Morgantown, WV 26506, USA. - - 2014
Given their extremely small size and light weight, carbon nanotubes (CNTs) can be readily inhaled by human lungs resulting in increased rates of pulmonary disorders, particularly fibrosis. Although the fibrogenic potential of CNTs is well established, there is a lack of consensus regarding the contribution of physicochemical attributes of CNTs ...
Campbell Jacob J Developmental Neuroscience, Munroe-Meyer Institute, University of Nebraska Medical Center Omaha, NE, - - 2014
Synaptic activity is intimately linked to neuronal structure and function. Stimulation of live cultured primary neurons, coupled with fluorescent indicator imaging, is a powerful technique to assess the impact of synaptic activity on neuronal protein trafficking and function. Current technology for neuronal stimulation in culture include chemical techniques or microelectrode ...
Liu Yu Y National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, China. - - 2014
Polyethylenimine (PEI) has attracted much attention as a DNA condenser, but its toxicity and non-specific targeting limit its potential. To overcome these limitations, Antheraea pernyi silk fibroin (ASF), a natural protein rich in arginyl-glycyl-aspartic acid (RGD) peptides that contains negative surface charges in a neutral aqueous solution, was used to ...
Niu Yunfei Y Department of Orthopedic Surgery, Changhai Hospital, Second Military Medical University, Shanghai, People's Republic of - - 2014
Mesoporous magnesium silicate (m-MS) and poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) (PCL-PEG-PCL) composite (m-MPC) was synthesized by solvent casting method. The results suggest that the mechanical properties of compressive strength and elastic modulus, as well as hydrophilicity, of the m-MPC increased with increase of m-MS content in the composites. In addition, the weight loss ...
Sharp Thomas T School of Computer Science, The University of Manchester Manchester, UK ; Laboratory for Neural Circuit Theory, RIKEN Brain Science Institute, Wakoshi Saitama, - - 2014
Simulations of neural circuits are bounded in scale and speed by available computing resources, and particularly by the differences in parallelism and communication patterns between the brain and high-performance computers. SpiNNaker is a computer architecture designed to address this problem by emulating the structure and function of neural tissue, using ...
Li Yan Y MOE Key Laboratory of Pollution Processes and Environmental Criteria, College of Environmental Science and Engineering, Nankai University, Tianjin 300071, China. - - 2014
Trichloroethylene (TCE) is a common groundwater contaminant of toxic and carcinogenic concern. Aerobic co-metabolic processes are the predominant pathways for TCE complete degradation. In this study, Pseudomonas fluorescens was studied as the active microorganism to degrade TCE under aerobic condition by co-metabolic degradation using phenol and gasoline as growth substrates. ...
Cichon Nicole B NB Developmental Neurophysiology, Neuroanatomy, University Medical Center Hamburg-Eppendorf Hamburg, - - 2014
Flexible communication within the brain, which relies on oscillatory activity, is not confined to adult neuronal networks. Experimental evidence has documented the presence of discontinuous patterns of oscillatory activity already during early development. Their highly variable spatial and time-frequency organization has been related to region specificity. However, it might be ...
Yamamoto Takanobu T Department of Cell Biology and Molecular Medicine, Cardiovascular Research Institute, Rutgers New Jersey Medical School, Newark, New Jersey, United States of - - 2014
Nicotinamide phosphoribosyltransferase (Nampt), the rate-limiting enzyme for nicotinamide adenine dinucleotide (NAD+) synthesis, and Sirt1, an NAD+-dependent histone deacetylase, protect the heart against ischemia/reperfusion (I/R). It remains unknown whether Nampt mediates the protective effect of ischemic preconditioning (IPC), whether nicotinamide mononucleotide (NMN, 500 mg/kg), a product of Nampt in the NAD+ ...
Jansson Keith H KH Laboratory for Cancer Ontogeny and Therapeutics, Department of Biological Sciences, University of Delaware, Newark, Delaware, United States of America; The Center for Translational Cancer Research, University of Delaware, Newark, Delaware, United States of - - 2014
Prostate cancer (PCa) is believed to metastasize through the blood/lymphatics systems; however, PCa may utilize the extensive innervation of the prostate for glandular egress. The interaction of PCa and its nerve fibers is observed in 80% of PCa and is termed perineural invasion (PNI). PCa cells have been observed traveling ...
Pelletier Amandine A PériTox Laboratory, UMR-I 01 INERIS, Faculty of Medicine, Jules Verne University of Picardy, Amiens, - - 2014
Some studies have shown that people living near a mobile phone base station may report sleep disturbances and discomfort. Using a rat model, we have previously shown that chronic exposure to a low-intensity radiofrequency electromagnetic field (RF-EMF) was associated with paradoxical sleep (PS) fragmentation and greater vasomotor tone in the ...
Kim Baek Hyun BH Department of Electrical and Computer Engineering, University of Missouri, Columbia, MO 65211, United - - 2014
The field of conventional energy conversion using radioisotopes has almost exclusively focused on solid-state materials. Herein, we demonstrate that liquids can be an excellent media for effective energy conversion from radioisotopes. We also show that free radicals in liquid, which are continuously generated by beta radiation, can be utilized for ...
Everett J J Institute for Science and Technology in Medicine, Keele University, , Stoke-on-Trent, Staffordshire ST4 7QB, - - 2014
For decades, a link between increased levels of iron and areas of Alzheimer's disease (AD) pathology has been recognized, including AD lesions comprised of the peptide β-amyloid (Aβ). Despite many observations of this association, the relationship between Aβ and iron is poorly understood. Using X-ray microspectroscopy, X-ray absorption spectroscopy, electron ...
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