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Gebrie Higemengist A - - 2014
No study has been carried out to assess the blood lead levels of workers or the contribution of common workplace practices to lead exposure in Ethiopia. This study was carried out to assess the blood lead levels of female and male laborers in the construction sector in Jimma town, Ethiopia. ...
Damous Luciana Lamarão LL Gynecology Division, Department of Obstetrics and Gynecology, Laboratory of Structural and Molecular Gynecology (LIM-58), Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil. - - 2014
Cryopreservation of the ovarian tissue has shown promising results. However, there remain controversial issues such as the short half-life of grafts. In this aspect, there are some evidences that preconditioning the ovarian tissue before transplantation is beneficial. To determine the effect of hypoxic preconditioning in vitro on ovarian tissue prior ...
Boenisch Maximilian - - 2014
Since the original characterizations of the pathological features defining glomerulonephritis in systemic lupus erythematosus (SLE) were reported, numerous studies have linked the development of pathology to the abnormal expression of protein in urine. The determination of proteinuria is important and necessary; however, this alone is not predictive enough to confirm ...
An J J College of Animal Science and Technology, Northwest A&F University, Shaanxi, - - 2014
Self-renewal and differentiation of spermatogonial stem cells (SSCs) are the foundation of spermatogenesis throughout a male's life. SSC transplantation will be a valuable solution for young male patients to preserve their fertility. As SSCs in the collected testis tissue from the patients are very limited, it is necessary to expansion ...
Pathak Ajay D AD Department of Veterinary Public Health, ICAR Research Complex for Goa, Old Goa, - - 2014
Background : Brucellosis is a widespread zoonotic infection. This disease is endemic in many parts of Asia, including India. Brucellosis is a major cause of pyrexia of unknown origin (PUO). Persons exposed to infected animals or contaminated animal products are at high risk. Seropositivity among animal handlers, veterinarians and dairy ...
Devor Eric J EJ Department of Obstetrics and Gynecology, University of Iowa Carver College of Medicine, 3234 MERF, Iowa City, IA 52242, - - 2014
Placenta-specific protein 1 (PLAC1) is a secreted protein found in trophoblasts. Several reports implicate a central role for PLAC1 in establishment and maintenance of the placenta. In addition to placentae PLAC1 is expressed in a variety of solids including breast, endometrial, and ovarian cancers. In order to show that PLAC1 ...
Maurya Vineet Kumar - - 2014
Polycystic ovarian syndrome (PCOS) is characterized by the presence of multiple follicular cysts, giving rise to infertility due to anovulation. This syndrome affects about 10% of women, worldwide. The exact molecular mechanism leading to PCOS remains obscure. RhoGTPase has been associated with oogenesis, but its role in PCOS remains unexplored. ...
Karbek Basak B Department of Endocrinology and Metabolic Diseases, Gaziantep Dr, Ersin Arslan Hospital, Milli Egemenlik bulvarı, Sanlılar Apt, no:51 daire:9 Şehitkamil/Gaziantep, Gaziantep, Turkey. - - 2014
Women with polycystic ovary syndrome (PCOS) have higher risk for cardiovascular disease (CVD). Copeptin has been found to be predictive for myocardial ischemia. We tested whether copeptin is the predictor for CVD in PCOS patients, who have an increased risk of cardiovascular disease. This was a cross sectional controlled study ...
Takahashi Tsukasa T Department of Applied Developmental Biology, Central Institute for Experimental Animals, Kawasaki-ku, Kawasaki, Kanagawa, Japan; Department of Biochemistry, Keio University School of Medicine, Shinjuku-ku, Tokyo, - - 2014
Intracytoplasmic sperm injection (ICSI), an important method used to treat male subfertility, is applied in the transgenic technology of sperm-mediated gene transfer. However, no study has described successful generation of offspring using ICSI in the common marmoset, a small non-human primate used as a model for biomedical translational research. In ...
Greco Ermanno E Center for Reproductive Medicine, European Hospital, Via Portuense 700, 00149 Rome, - - 2014
The aim of this study is to determine if the use of preimplantation genetic screening (PGS) by array comparative genomic hybridization (array CGH) and transfer of a single euploid blastocyst in patients with repeated implantation failure (RIF) can improve clinical results. Three patient groups are compared: 43 couples with RIF ...
- - 2014
This paper proves the correlation between characteristics of blood flow rate in the renal veins and resistance indices of the renal arteries. As a result of polypositional assessment of venous blood flow, it was found that the violations of magistral venous blood flow in the left kidney can affect the ...
Wang Shao-Jun SJ Institute of Acupuncture and Moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, - - 2014
It had been indicated in the previous studies that acupuncture relieved the excessive excitation of hypothalamic-pituitary-adrenal cortex axis (HPAA) function induced by stress stimulation. But the changes in glucocorticoid receptor (GR) induced by acupuncture have not been detected clearly. The objective of the study was to observe the impacts of ...
Konc János J Infertility and IVF Center of Buda, Szent János Hospital, Budapest 1125, - - 2014
Both sperm and embryo cryopreservation have become routine procedures in human assisted reproduction and oocyte cryopreservation is being introduced into clinical practice and is getting more and more widely used. Embryo cryopreservation has decreased the number of fresh embryo transfers and maximized the effectiveness of the IVF cycle. The data ...
Damario Mark A MA Department of Obstetrics, Gynecology and Women's Health, University of Minnesota, MMC 395 Mayo, 8395C (Campus Delivery Code), 420 Delaware St SE, Minneapolis, MN, 55455, USA, - - 2014
Fertility rates have been declining in most Western nations over the past several decades, although it is not entirely clear if an increased rate of infertility substantially contributes to this. As compared to other species, the reproductive efficiency of humans is relatively low. Factors related to fertility include age, exposure ...
Lin Yi-Nan YN Institute of Biomedical Sciences, Academia Sinica, Taipei, - - 2014
Early in embryogenesis, cells that are destined to become germ cells take on a different destiny from other cells in the embryo. The germ cells are not programmed to perform "vital" functions but to perpetuate the species through the transfer of genetic materials to the next generation. To fulfill their ...
Or Yuval Y Department of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, - - 2014
In a normal spontaneous menstrual cycle, the luteal phase is characterized by the production and secretion of estradiol (E) and progesterone (P) from the corpus luteum (CL) in an episodic manner. The steroidogenesis of the CL is dependent on continued tonic luteinizing hormone (LH) secretion (Fritz and Speroff, Clinical gynecologic ...
Gosden Roger G RG Weill Cornell Medical College, 1300 York Avenue, New York, NY, 10065, USA, - - 2014
Cryopreservation quickly became a cornerstone technology in assisted reproduction because the banking of gametes, embryos, and gonadal tissues has increased the effectiveness of assisted reproductive technology cycles for infertility treatment as well as fertility preservation for patients at risk of premature sterilization. Cryopreservation protocols, both slow/equilibrium cooling and vitrification methods, ...
Davis Owen K OK Weill Medical College of Cornell University, Center of Reproductive Medicine and Infertility, 1305 York Avenue, New York, NY, 10021, USA, - - 2014
One of the most vexing challenges in the practice of reproductive medicine is the management of the "poor responder," specifically the patient manifesting an inadequate follicular response to ovarian stimulation. Poor response predicts a reduction in the number of mature oocytes retrieved, with the consequences of fewer embryos available for ...
Palermo Gianpiero D GD The Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, Weill Cornell Medical College, 1305 York Avenue, Suite 720, New York, NY, 10021, USA, - - 2014
Major difficulties exist in the accurate and meaningful diagnosis of male reproductive dysfunction, and our understanding of the epidemiology and etiology of male infertility has proven quite complex.The numerous spermatozoa produced in mammals and other species provides some degree of protection against adverse environmental conditions represented by physical and chemical ...
Nagy Zsolt Peter ZP Reproductive Biology Associates, 1100 Johnson Ferry Road, Atlanta, GA, 30342, USA, - - 2014
Oocyte cryopreservation is playing an increasingly important role in the field of human infertility treatment. The ability to store viable oocytes for later use has given many women the option to delay childbearing in order to pursue other ventures in life, without the concern of losing the opportunity to have ...
Xu Kangpu K Center of Reproductive Medicine and Infertility, Weill Medical College of Cornell University, 1305 York Avenue, New York, NY, 10021, - - 2014
This chapter highlights the methodologies of single cell genetic diagnosis along with the strengths and weaknesses of existing techniques.
Lucock Mark M School of Environmental and Life Sciences, Biomedical Sciences and Pharmacy, Maths and Physical Sciences, University of Newcastle, PO Box 127, Brush Road, Ourimbah, NSW 2258, Australia, The Pennsylvania State University, Anthropology Department, 409 Carpenter Building, University Park, PA 16802, USA, and Teaching and Research Unit, Central Coast Local Health District, PO Box 361, Gosford, NSW 2250, - - 2014
Vitamin D and folate are highly UV sensitive, and critical for maintaining health throughout the lifecycle. This study examines whether solar irradiance during the first trimester of pregnancy influences vitamin D receptor (VDR) and nuclear folate gene variant occurrence, and whether affected genes influence late-life biochemical/clinical phenotypes. 228 subjects were ...
Tang L S - - 2014
The aim of this study was to evaluate the related factors between abnormal ultrasonic appearance of ovarian and pelvic adhesion in infertile women. Forty-eight cases were examined with transvaginal ultrasonography (TVUS) if there was pelvic adhesion before surgery (experiment group), and the surgical group was used as control. The specificity ...
Simpson Joe Leigh JL Department of Human and Molecular Genetics, Herbert Wertheim College of Medicine, Florida International University, 11200 SW 8th Street, AHC2 693, Miami, FL, 33199, USA, - - 2014
Genetic factors are pivotal in reproductive development and subsequent reproductive processes. If disturbed, infertility can occur. In the female, genetic factors affecting the ovary and the uterus are not uncommon causes of infertility. Terminal deletions on the X long arm and X short arm and X chromosomal mosaicism have long ...
Casarini Livio L Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Universtita 4, Modena, 41121, - - 2014
This chapter presents an overview of the gene polymorphisms underlying the functions of ovarian receptors and their clinical implications in the female fecundity. A selection of genetic studies revealing significant associations between receptor polymorphisms, gene mutations, and some pathological conditions (i.e., female infertility, premature ovarian failure, polycystic ovary syndrome, endometriosis) ...
Funaro Michael M Department of Urology and Reproductive Medicine, Weill Cornell Medical College, New York, NY, - - 2014
Diagnostic tests should detect disease, have prognostic value, and aid in clinical decision making. Nowhere else in laboratory medicine does one have to interpret a subject's results within the dynamic of a couple as in reproductive medicine. Abnormal markers of male reproduction do not necessarily mean sterility, but instead indicate ...
Chian Ri-Cheng RC Department of Obstetrics and Gynecology, McGill University, Royal Victoria Hospital, Women's Pavilion F3, 687 Pine Avenue West, Montreal, Quebec, Canada, H3A 1A1, - - 2014
Meiotic progression in the oocyte is defined as oocyte maturation from reinitiation of the first meiotic division from the germinal vesicle (GV) stage to the metaphase-II (M-II) stage (Fig. 1), (Cha and Chian, Hum Reprod Update 4:103-120, 1998). Priming with FSH or HCG prior to immature oocyte retrieval improves oocyte ...
Reichman David D Center of Reproductive Medicine and Infertility, Weill Medical College of Cornell University, New York, NY, USA, - - 2014
In this chapter we elaborate on the intricacies of employing GnRH antagonists for prevention of the endogenous luteinizing hormone surge during IVF. Several practical aspects of implementing a GnRH antagonist-based stimulation protocol are described; selection of the correct dose, choosing when to start the antagonist, programming of cycle starts, selection ...
Hegde Aparna A Division of Reproductive Endocrinology and Infertility, Department of OB/GYN, Stanford University, Stanford, CA, - - 2014
In this chapter, we have outlined the various morphological criteria for selection of the best embryo at each important milestone encountered in the progress from the oocyte to the blastocyst. As Gerris et al. stated, a combination of one, two, or even three selection points should lead to a more ...
Medrano Jose V JV CIPF & Fundación Instituto Valenciano de Infertilidad (FIVI), Valencia University, INCLIVA, Valencia, 46015, - - 2014
Although 10-15 % of couples are infertile, little is known of the diverse, underlying pathologies in men and women with poor germ cell production; furthermore, for those with few or no high-quality germ cells, there are few options available for treatment. Thus, over the last decade, concerted efforts have been ...
Indraccolo U - - 2014
To demonstrate that office hysteroscopy has a key-role in the diagnostic work-up of infertile couples. The entire database of hysteroscopies performed in 572 menstruated women from 2008 to 2011, was retrospectively analyzed. A two-dimensional correspondence analysis among endometrial patterns, age ranges, and indication for hysteroscopies was made. A main-effect hierarchical ...
Kalampokas T - - 2014
Homeopathy has been used in the past for treating a broad aspect of diseases. In gynecology, its use remains limited. Taking under consideration its clinical aspects, the authors attempted to use it for treating female sub fertility problems. With this study, the authors present five cases of female infertility treated ...
Liu B - - 2014
The synchronization of the uterus and mature eggs at the molecular level is the key factor in embryo transfer, and the regulation of synchronization depends on a variety of cytokines. C-reactive protein (CRP), as the first acute phase reaction protein, is involved in the entire process of embryo transfer. The ...
Gizzo Salvatore S Department of Woman and Child Health, University of Padua, 35128 Padua, - - 2014
Recent evidences identify Human Papillomavirus (HPV) sperm infection as a possible cause of male and couple infertility. It acts through different mechanisms at various steps of human conception and early gestational development. We performed a systematic review to assess the role of HPV semen infection on male and couple infertility. ...
Grotegut Chad A CA Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University, Durham, North Carolina, United States of - - 2014
The number of women aged 45 and older who become pregnant is increasing. The objective of this study was to estimate the risk of medical and obstetric complications among women aged 45 and older. The Nationwide Inpatient Sample was used to identify pregnant woman during admission for delivery. Deliveries were ...
Jung Yong Wook YW Department of Obstetrics and Gynecology, CHA Gangnam Medical Center, CHA University, Seoul, South - - 2014
Key molecules involved in microRNA (miRNA) biogenesis, such as DROSHA, XPO5, and DICER, have been identified in trophoblast cells, confirming that the miRNA biogenesis pathway is active in human placenta. In addition, miRNAs regulate uterine gene expression associated with inflammatory responses during the peri-implantation period and participate in maternal-fetal immune ...
Cacioppo Joseph A JA Comparative Biosciences, College of Veterinary Medicine, University of Illinois, Urbana-Champaign, Illinois, United States of - - 2014
Endothelin-2 (EDN2), a potent vasoconstrictive peptide, is transiently produced by periovulatory follicles at the time of ovulation when corpus luteum (CL) formation begins. EDN2 induces contraction of ovarian smooth muscles ex vivo via an endothelin receptor A-mediated pathway. In this study, we aimed to determine if EDN2 is required for ...
Jerchel Stefan S Institute of Medical Microbiology and Hygiene, University of Lübeck Lübeck, - - 2014
Genital tract infections with Chlamydia trachomatis (C. trachomatis) are the most frequent sexually transmitted disease worldwide. Severe clinical sequelae such as pelvic inflammatory disease (PID), tubal occlusion, and tubal infertility are linked to inflammatory processes of chronically infected tissues. The oxygen concentrations in the female urogenital tract are physiologically low ...
Rudov Alexander A Department of Biomolecular Sciences, University of Urbino, Via Saffi 2, 61029 Urbino, - - 2014
Oxidative stress (OS) is known to be strongly involved in a large number of fetal, neonatal, and adult diseases, including placental disorders, leading to pregnancy loss and stillbirths. A growing body of research links OS to preeclampsia, gestational diabetes, obesity, spontaneous abortion, recurrent pregnancy, preterm labor, and intrauterine growth restriction. ...
Kintner Jennifer J Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University Johnson City, TN, - - 2014
Chlamydia trachomatis, the most common bacterial sexually transmitted disease agent worldwide, enters a viable, non-dividing and non-infectious state (historically termed persistence and more recently referred to as the chlamydial stress response) when exposed to penicillin G in culture. Notably, penicillin G-exposed chlamydiae can reenter the normal developmental cycle upon drug ...
Terayama Hayato H Department of Anatomy, Tokyo Medical University, Tokyo, Japan; Department of Anatomy, Tokai University School of Medicine, Kanagawa, - - 2014
The testis is an organ with immune privilege. The comprehensive blood-testis barrier formed by Sertoli cells protects autoimmunogenic spermatozoa and spermatids from attack by the body's immune system. The interleukin (IL)-6/IL-12 family cytokines IL-12 (p35/p40), IL-23 (p19/p40), IL-27 (p28/Epstein-Barr virus-induced gene 3 [EBI3]), and IL-35 (p35/EBI3) play critical roles in ...
Mai Zixin Z Department of Reproductive Medicine Center, Key Laboratory for Reproductive Medicine of Guangdong Province, Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, - - 2014
Cigarette smoking can harm fertility, but the existing research has targeted primarily on ovarian follicles, embryos or sex hormone. In this study, we tested cigarette smoke extract on ovulation, oocyte morphology and ovarian gene expression associated with inhibition of oxidative stress using C57BL/6 mice. Mice in the experimental group were ...
Michalkova Veronika V Department of Epidemiology of Microbial Diseases, Yale School of Public Health, New Haven, Connecticut, United State of America; Section of Molecular and Applied Zoology, Institute of Zoology, Slovak Academy of Sciences, Bratislava, - - 2014
Impact of reproductive processes upon female health has yielded conflicting results; particularly in relation to the role of reproduction-associated stress. We used the viviparous tsetse fly to determine if lactation, birth and involution lead to damage from oxidative stress (OS) that impairs subsequent reproductive cycles. Tsetse females carry an intrauterine ...
Ferramosca Alessandra A Dipartimento di Scienze e Tecnologie Biologiche ed Ambientali, Università del Salento, Via Provinciale Lecce-Monteroni, 73100 Lecce, - - 2014
After ejaculation, the mammalian male gamete must undergo the capacitation process, which is a prerequisite for egg fertilization. The bioenergetics of sperm capacitation is poorly understood despite its fundamental role in sustaining the biochemical and molecular events occurring during gamete activation. Glycolysis and mitochondrial oxidative phosphorylation (OXPHOS) are the two ...
Bosteels Jan J Department of Obstetrics and Gynaecology, Imeldahospitaal, Imeldalaan 9, 2820 Bonheiden, Belgium ; CEBAM, Centre for Evidence-based Medicine, the Belgian Branch of the Dutch Cochrane Centre, ACHG, Kapucijnenvoer 33, blok J bus 7001, 3000 Leuven, - - 2014
The aim of this study was to assess the effects of any anti-adhesion barrier gel used after operative hysteroscopy for treating infertility associated with uterine cavity abnormalities. Gynecologists might use any barrier gel following operative hysteroscopy in infertile women for decreasing de novo adhesion formation; the use of any barrier ...
Imamovic Kumalic Senka S 0000-0002-4421-7266 Reproductive Unit, Division of Gynecology and Obstetrics, University Medical Centre Ljubljana, Slajmerjeva 3, 1000 Ljubljana, - - 2014
Infertility affects 50 to 80 million people worldwide. Male factor is a cause of infertility in almost half of cases, mainly due to oligoasthenoteratozoospermia (OAT). With common diagnostic methods no cause can be found in approximately 30% of cases of male infertility due to OAT and these are considered idiopathic. ...
Santoro Luca L 0000-0003-3614-7314 Department of Internal Medicine, Catholic University of Rome, 00168 Rome, Italy ; Integrated Complex Columbus-Gemelli Hospital, Department of Internal Medicine, Catholic University of Rome, Via Giuseppe Moscati 31, 00168 Rome, - - 2014
In the last years, a potential link between endometriosis and celiac disease has been hypothesized since these disorders share some similarities, specifically concerning a potential role of oxidative stress, inflammation, and immunological dysfunctions. We investigated the prevalence of celiac disease among Italian women with endometriosis with respect to general population. ...
Abba Yusuf Y 0000-0001-7888-9004 Department of Veterinary Pathology, Faculty of Veterinary Medicine, University of Maiduguri, PMB 1069, Maiduguri, Borno State, Nigeria ; Department of Veterinary Pathology and Microbiology, Faculty of Veterinary Medicine, Universiti Putra Malaysia, 43400 Serdang, Selangor, - - 2014
The study of pathological conditions of the male reproductive system is paramount to understanding reproductive inefficiency in the Sahel goat. In this study, 1048 Sahel bucks presented for slaughter at the Maiduguri metropolitan abattoir were evaluated for the presence of various pathological abnormalities of the reproductive system. A total incidence ...
Xin Ai-Jie - - 2014
It is well known that cell surface glycans or glycocalyx play important roles in sperm motility, maturation and fertilization. A comprehensive profile of the sperm surface glycans will greatly facilitate both basic research (sperm glycobiology) and clinical studies, such as diagnostics of infertility. As a group of natural glycan binders, ...
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