Search Results
Results 1951 - 2000 of 76837

Current sort is by publication date. Click to sort by relevancy

< 35 36 37 38 39 40 41 42 43 44 45 >
Eriksson Wiklund Ann-Kristin AK Department of Applied Environmental Science, Stockholm University, Stockholm, - - 2014
The intense artificial sweetener sucralose has no bioconcentration properties, and no adverse acute toxic effects have been observed in standard ecotoxicity tests, suggesting negligible environmental risk. However, significant feeding and behavioural alterations have been reported in non-standard tests using aquatic crustaceans, indicating possible sublethal effects. We hypothesized that these effects ...
Sugawara Kana K 1] Department of Obstetrics and Gynecology, Keio University School of Medicine, 35 Shinanomachi Shinjuku-ku, Tokyo 160-8582, Japan [2] Department of Reproductive Biology, National Research Institute for Child Health and Development, 2-10-1 Ohkura Setagaya-ku, Tokyo 157-8535, - - 2014
We induced differentiation of human amnion-derived mesenchymal stem cells (AMCs) and menstrual blood-derived mesenchymal stem cells (MMCs) into endometrial stroma-like cells, which could be useful for cell therapy to support embryo implantation. Interestingly, the expression patterns of surface markers were similar among AMCs, MMCs, and endometrial stromal cells. In addition, ...
Mynbaev Ospan A OA The International Translational Medicine & Biomodeling Research Group, Department of Applied Mathematics, Moscow Institute of Physics & Technology (State University), 9 institutsky per, Dolgoprudny, Moscow Region 141700, Russia. - - 2014
Tihtonen Kati - - 2014
During the last few decades the cesarean delivery rate has been around 15% in Finland. It has remained moderate compared with USA where 30% of women deliver by cesarean section. Compared with vaginal delivery, cesarean section is associated with a three- to sixfold risk of severe complications. Furthermore, it increases ...
Rajaei Minoo M Hormozgan Fertility and Infertility Research Center, Hormozgan University of Medical Sciences (HUMS), Bandar Abbas, - - 2014
Postpartum hemorrhage (PPH) is the commonest cause of maternal death worldwide. Studies suggest that the use of misoprostol may be beneficial in clinical settings where oxytocin is unavailable. The aim of this study was to compare the safety and efficacy of oxytocin and misoprostol when used in the prevention of ...
Sharma Tusha T Environmental Biochemistry & Molecular Biology Laboratory, Department of Biochemistry, University College of Medical Sciences & GTB Hospital, University of Delhi, Dilshad Garden, Delhi 110095, - - 2014
Background. Hypospadias is a part of testicular digenesis syndrome (TDS) which includes infertility, cryptorchidism, and spermatogenesis. Heavy metals act as endocrine disrupting compounds. Heavy metals such as cadmium, chromium, arsenic, and lead have been associated with male infertility, cryptorchidism, spermatogenesis, cancer, reproductive disorder, and neurological disorder. However, it remains an ...
Hashemi A A Department of Pediatric Hematology oncology and Genetic Research Center, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, - - 2014
Monosomy is defined as the presence of only one chromosome instead of two in humans. Partial monosomy occurs when only a portion of the chromosome is present in a single copy, while the rest has two copies. It can occur in unbalanced translocations or deletions. In this report, a 6 ...
Kidder Benjamin L BL Systems Biology Center, National Heart, Lung and Blood Institute, National Institutes of Health, 10 Center Dr., Bldg 10, 7B04, Bethesda, MD, 20892, USA, - - 2014
Epigenetic regulation of gene expression in the germline is important for reproductive success of mammals. Misregulation of genes whose expression is correlated with reproductive success may result in subfertility or infertility. To study epigenetic events that occur during oocyte maturation and preimplantation embryo development, it is important to generate large ...
Conrad Sabine S Institute of Anatomy, University of Tübingen, Österbergstraße 3, 72074 Tübingen, - - 2014
This study aimed to provide a molecular signature for enriched adult human stem/progenitor spermatogonia during short-term (<2 weeks) and long-term culture (up to more than 14 months) in comparison to human testicular fibroblasts and human embryonic stem cells. Human spermatogonia were isolated by CD49f magnetic activated cell sorting and collagen(-)/laminin(+) ...
Gkourogianni Alexandra A Division of Endocrinology, Diabetes and Metabolism, First Department of Pediatrics, University of Athens Medical School, Athens, - - 2014
There have been increasing indications about an epigenetically-based elevated predisposition of assisted reproductive technology (ART) offspring to insulin resistance, which can lead to an unfavorable cardio-metabolic profile in adult life. However, the relevant long-term systematic molecular studies are limited, especially for the IntraCytoplasmic Sperm Injection (ICSI) method, introduced in 1992. ...
Chen Jianlin J Department of Microbiology and Immunology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States of America; Departments of Obstetrics and Gynecology, Pathology and Endocrinology, Second Xiangya Hospital, Central South University, Changsha, Hunan, - - 2014
The female lower genital tract is constantly exposed to microbial infection, some of which can ascend to and cause pathology such as hydrosalpinx in the upper genital tract, which can affect fertility. To understand host mechanisms for preventing upper genital tract pathology, we screened 11 inbred strains of mice for ...
Wildenschild Cathrine C Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, - - 2014
To examine the association between a woman's birth weight and her subsequent fecundability. In this prospective cohort study, we included 2,773 Danish pregnancy planners enrolled in the internet-based cohort study "Snart-Gravid", conducted during 2007-2012. Participants were 18-40 years old at study entry, attempting to conceive, and were not receiving fertility ...
Tsukiyama Tomoyuki T PRESTO, Japan Science and Technology Agency (JST), Kawaguchi, Saitama, Japan; Laboratory for Pluripotent Stem Cell Studies, RIKEN Center for Developmental Biology (CDB), Kobe, Hyogo, - - 2014
Embryonic stem cells (ESCs) can contribute to the tissues of chimeric animals, including the germline. By contrast, epiblast stem cells (EpiSCs) barely contribute to chimeras. These two types of cells are established and maintained under different culture conditions. Here, we show that a modified EpiSC culture condition containing the GSK3 ...
Kawano Natsuko N 1] Department of Reproductive Biology, National Research Institute for Child Health and Development, 2-10-1 Okura, Setagaya, Tokyo, Japan - - 2014
In mammals, uterine epithelium is remodeled cyclically throughout adult life for pregnancy. Despite the expression of CD9 in the uterine epithelium, its role in maternal reproduction is unclear. Here, we addressed this issue by examining uterine secretions collected from patients undergoing fertility treatment and fertilization-competent Cd9(-/-) mice expressing CD9-GFP in ...
Vaucher Laurent L Department of Urology and Reproductive Medicine, Weill Cornell Medical College, New York, New York, United States of America; Population Council, Center for Biomedical Research, New York, New York, United States of America; Department of Urology, Centre Hospitalier Universitaire Vaudois, Lausanne, - - 2014
Estradiol (E2) modulates testicular functions including steroidogenesis, but the mechanisms of E2 signaling in human testis are poorly understood. GPER-1 (GPR30), a G protein-coupled membrane receptor, mediates rapid genomic and non-genomic response to estrogens. The aim of this study was to evaluate GPER-1 expression in the testis, and its role ...
Willems Els E Laboratory of Livestock Physiology, Department of Biosystems, KU Leuven, Leuven, - - 2014
Different animal models have been used to study the effects of prenatal protein undernutrition and the mechanisms by which these occur. In mammals, the maternal diet is manipulated, exerting both direct nutritional and indirect hormonal effects. Chicken embryos develop independent from the hen in the egg. Therefore, in the chicken, ...
Shin Hyejin H Department of Biomedical Science & Technology, Institute of Biomedical Science & Technology, Konkuk University, Seoul, - - 2014
The early growth response (Egr) family of zinc finger transcription factors consists of 4 members. During an investigation of Egr factor localization in mouse ovaries, we noted that Egr3 exhibits a subcellular localization that overlaps with the meiotic spindle in oocytes. Using Egr3-specific antibodies, we establish that Egr3 co-localizes with ...
van den Berg Jolice P JP Department of Paediatrics, Division of Neonatology, VU University Medical Center, Amsterdam, The - - 2014
Maternal antibodies, transported over the placenta during pregnancy, contribute to the protection of infants from infectious diseases during the first months of life. In term infants, this protection does not last until the first recommended measles-mumps-rubella vaccination at 14 months in the Netherlands, while these viruses still circulate. The aim ...
Luo Yunjian Y Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese Academy of Sciences, Xiamen, - - 2014
Biomass conversion factors (BCFs, defined as the ratios of tree components (i.e. stem, branch, foliage and root), as well as aboveground and whole biomass of trees to growing stock volume, Mg m-3) are considered as important parameters in large-scale forest biomass carbon estimation. To date, knowledge of possible sources of ...
Song J H JH . - - 2014
A defect in Klotho gene expression in the mouse results in a syndrome that resembles rapid human aging. In this study, we investigated the detailed distribution and the time of the first appearance of Klotho in developing and adult mouse kidney. Kidneys from 16-(F16), 18-(F18) and 20-day-old (F20) fetuses, 1- ...
Ni Wuhua W Reproductive Medical Center, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, - - 2014
During the last decades, many studies have shown the possible influence of sperm DNA fragmentation on assisted reproductive technique outcomes. However, little is known about the impact of sperm DNA fragmentation on the clinical outcome of frozen-thawed embryo transfer (FET) from cycles of conventional in vitro fertilization (IVF) and intra-cytoplasmic ...
Räisänen Ulla U HERG Health Experiences Research Group, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, - - 2014
To understand how young men recognise eating disorder (ED) symptoms and decide to seek help, and to examine their experiences of initial contacts with primary care. A qualitative interview study. Men from across the UK were interviewed as part of a study of 39 young men's and women's experiences of ...
Erez Offer O Department of Obstetrics and Gynecology, Soroka University Medical Center, School of Medicine, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, - - 2014
The objectives of this study were: 1) To determine the component needed to generate a validated DIC score during pregnancy. 2) To validate such scoring system in the identification of patients with clinical diagnosis of DIC. This is a population based retrospective study, including all women who gave birth at ...
Greig Jane J Manson Unit, Médecins Sans Frontières, London, United - - 2014
In 2010, Médecins Sans Frontières (MSF) investigated reports of high mortality in young children in Zamfara State, Nigeria, leading to confirmation of villages with widespread acute severe lead poisoning. In a retrospective analysis, we aimed to determine venous blood lead level (VBLL) thresholds and risk factors for encephalopathy using MSF ...
Ramos-Ibeas Priscila P Dpto. de Reproducción Animal y Conservación de Recursos Zoogenéticos, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, Madrid, - - 2014
Intracytoplasmic sperm injection (ICSI) in mice using DNA-fragmented sperm (DFS) has been linked to an increased risk of genetic and epigenetic abnormalities both in embryos and offspring. This study examines: whether embryonic stem cells (ESCs) derived from DFS-ICSI embryos reflect the abnormalities observed in the DFS-ICSI progeny; the effect of ...
Dahl Mette M 0000-0002-8036-3519 Department of Clinical Biochemistry, Centre for Immune Regulation and Reproductive Immunology (CIRRI), Copenhagen University Hospital (Roskilde) and Roskilde Hospital, 7-13 Køgevej, 4000 Roskilde, - - 2014
Pregnancy is an immunological paradox, where fetal antigens encoded by polymorphic genes inherited from the father do not provoke a maternal immune response. The fetus is not rejected as it would be theorized according to principles of tissue transplantation. A major contribution to fetal tolerance is the human leukocyte antigen ...
Zivković D D Institute for Child and Youth Health Care of Vojvodina, 21000 Novi Sad, Serbia ; Medical Faculty, University of Novi Sad, 21000 Novi Sad, - - 2014
Male reproductive function in the general population raises an increased attention due to reports indicating declining sperm counts, increased occurrence of testicular cancer, cryptorchidism, and hypospadias. It is also hypothesized that prolonged exposure of the developing male, during both fetal and postnatal life, to exogenous estrogens could reduce Sertoli cell ...
Hwang In-Sul IS 0000-0003-2949-3075 Interdisciplinary Graduate School of Science and Technology, Shinshu University, Tokida 3-15-1, Ueda, Nagano 386-8567, Japan ; Animal Biotechnology Division, National Institute of Animal Science, Rural Development Administration, Seosuwon-ro 143-13, Suwon, Gyeonggi-do 441-706, Republic of - - 2014
Principle of oocyte cryoinjury is first overviewed and then research history of cryopreservation using bovine oocytes is summarized for the last two decades with a few special references to recent progresses. Various types of cryodevices have been developed to accelerate the cooling rate and applied to the oocytes from large ...
Fu Weihua W Department of Urology, Southwest Hospital, Third Military Medical University, Chongqing, People's Republic of - - 2014
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is one of the risk factors of impaired male fertility potential. Studies have investigated the effect of CP/CPPS on several semen parameters but have shown inconsistent results. Hence, we performed a systematic literature review and meta-analysis to assess the association between CP/CPPS and basic ...
Reekie Joanne J The Kirby Institute, UNSW Australia, Sydney, - - 2014
The presence and severity of pelvic inflammatory disease (PID) symptoms are thought to vary by microbiological etiology but there is limited empirical evidence. We sought to estimate and compare the rates of hospitalisation for PID temporally related to diagnoses of gonorrhoea and chlamydia. All women, aged 15-45 years in the ...
Lakos Gabriella G 0000-0003-2856-3617 INOVA Diagnostics, Inc., 9900 Old Grove Road, San Diego, CA 92131-1638, - - 2014
Objective. Here we compared analytical and clinical performance characteristics of two novel automated assay systems for the detection of celiac disease (CD) specific antibodies: QUANTA Flash (INOVA Diagnostics, Inc.) and EliA (Thermo Scientific). Methods. A total of 74 biopsy-proven CD patients (2 with IgA deficiency) and 138 controls were tested ...
Buczkowska Justyna - - 2014
Endometritis is a major cause of infertility in the mare. Therefore, the diagnosis of this disease is very important in veterinary practice. The objective of this study was to compare bacteriological and cytological results obtained from the mare uterus using biopsy (EB) and cytobrush (CB) techniques and relating these findings ...
Fanson Kerry V KV Wildlife Reproductive CentreTaronga Conservation Society Australia, Dubbo, New South Wales, Australia School of Life and Environmental SciencesDeakin University, 75 Pigdons Road, Waurn Ponds, Victoria 3217, Australia School of Agriculture and Food SciencesUniversity of Queensland, Gatton, Queensland, - - 2014
In the context of reproduction, glucocorticoids (GCs) are generally considered to have negative effects. However, in well-studied model species, GCs fluctuate predictability across the estrous cycles, and short-term increases promote healthy ovarian function. Reproductive challenges have plagued captive elephant populations, which are not currently self-sustaining. Efforts to understand reproductive dysfunction ...
Sliwa Leopold - - 2014
The inflammation of the reproductive system can affect reproduction causing partial or complete infertility. It is well known that lipopolysaccharide (LPS) triggers an inflammatory response in the whole organism, including immunologically privileged organs, e.g. the testicles. Adult male TCRalpha-/-, TCRdelta-/-, CD1d-/- and beta2m-/- on B10.PL (H-2(u)) and B10.PL control mice ...
Lalasa Godavarthi G Departments of Periodontics and Oral Implantology, GITAM Dental College and Hospital, Visakhapatnam, Andhra Pradesh, - - 2014
Background and Aim: Throughout a woman's life, hormonal influences affect therapeutic decision making in periodontics. A woman undergoing infertility treatment is given drugs to stimulate the ovaries, which lead to sustained higher levels of female sex hormones. The differing levels of these hormones, either in infertile women or in women ...
Boukhanni Lahcen L 0000-0002-2006-9465 Department of Obstetrics and Gynecology, University Hospital of Marrakesh, Cadi Ayyad University, 40 000 Marrakesh, Morocco ; Department of Obstetrics & Gynecology, Mother and Child Hospital, Mohammed VI University Hospital, Cadi Ayyad University, School of Medicine, 40 000 Marrakesh, - - 2014
Intramyometrial pregnancy is a rare form of ectopic pregnancy. It makes a diagnostic and therapeutic challenge. If misdiagnosed the intramyometrial pregnancy can cause a uterine rupture and become life-threatening condition. We report a case of intramyometrial pregnancy in twin pregnancy following IVF with spontaneous abortion of the first twin At ...
Medhi Robin R Department of obstetrics and gynaecology, Silchar Medical College and Hospital, Silchar, Assam 788014 - - 2014
Yaman Ferda F Anesthesiology and Reanimation Department, Kırıkkale University, Kırıkkale, - - 2014
A critical aspect of safe general anesthesia is providing adequate ventilation and oxygenation. Failed endotracheal intubation and inadequate ventilation with insufficient oxygenation may lead to serious complications, even death. Anesthesiologists rarely encounter unexpected difficult airway problems in daily routine. Management of an unexpectedly difficult airway consists of laryngeal mask ventilation, ...
Cucinotta Mara M Dipartimento di Bioscienze, Università degli Studi di Milano Milan, - - 2014
In spermatophytes the ovules upon fertilization give rise to the seeds. It is essential to understand the mechanisms that control ovule number and development as they ultimately determine the final number of seeds and, thereby, the yield in crop plants. In Arabidopsis thaliana, ovules arise laterally from a meristematic tissue ...
Fecher-Trost Claudia C Institut für Experimentelle und Klinische Pharmakologie und Toxikologie, Universität des Saarlandes, 66421, Homburg, - - 2014
TRPV6 (former synonyms ECAC2, CaT1, CaT-like) displays several specific features which makes it unique among the members of the mammalian Trp gene family (1) TRPV6 (and its closest relative, TRPV5) are the only highly Ca(2+)-selective channels of the entire TRP superfamily (Peng et al. 1999; Wissenbach et al. 2001; Voets ...
Running Mark P MP Department of Biology, University of Louisville Louisville, KY, - - 2014
Most eukaryotic proteins are post-translationally modified, and modification has profound effects on protein function. One key modification is the attachment of a lipid group to certain amino acids; this typically facilitates subcellular targeting (association with a membrane) and protein-protein interactions (by virtue of the large hydrophobic moiety). Most widely recognized ...
Bloch Donald B DB Center for Immunology and Inflammatory Diseases, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America; Anesthesia Center for Critical Care Research, Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of - - 2014
The mRNA processing body (P-body) is a cellular structure that regulates the stability of cytoplasmic mRNA. MARF1 is a murine oocyte RNA-binding protein that is associated with maintenance of mRNA homeostasis and genomic stability. In this study, autoantibodies were used to identify Limkain B (LMKB), the human orthologue of MARF1, ...
Adegbesan-Omilabu M A MA Department of Obstetrics & Gynaecology, Lagos University Teaching Hospital (LUTH), Lagos, - - 2014
Objectives. The study was to assess the level of knowledge of, perception of, and attitude towards uterine fibroids among women diagnosed with the condition. Methods. It is a cross-sectional descriptive study carried out among women diagnosed as having uterine fibroids in two gynaecological clinics in Lagos, Nigeria. Eligible women were ...
Umamaheswaran Gurusamy - - 2014
Phase I and II drug metabolizing enzymes (DME) and drug transporters are involved in the absorption, distribution, metabolism as well as elimination of many therapeutic agents, toxins and various pollutants. Presence of genetic polymorphisms in genes encoding these proteins has been associated with marked inter-individual variability in their activity that ...
Craig Paul M PM Department of Biology and Centre for Advanced Research in Environmental Genomics, University of Ottawa, Ottawa, Ontario, - - 2014
This study examined the similarities in microRNA profiles between fasted and fluoxetine (FLX) exposed zebrafish and downstream target transcripts and biological pathways. Using a custom designed microarray targeting 270 zebrafish miRNAs, we identified 9 differentially expressed miRNAs targeting transcripts in biological pathways associated with anabolic metabolism, such as adipogenesis, cholesterol ...
Flachs Petr P Department of Mouse Molecular Genetics, Institute of Molecular Genetics of the Academy of Sciences of the Czech Republic, v.v.i., Prague, Czech - - 2014
PR-domain 9 (Prdm9) is the first hybrid sterility gene identified in mammals. The incompatibility between Prdm9 from Mus musculus domesticus (Mmd; the B6 strain) and the Hstx2 region of chromosome (Chr) X from M. m. musculus (Mmm; the PWD strain) participates in the complete meiotic arrest of mouse intersubspecific (PWD×B6)F1 ...
Mullen Michael P MP Teagasc, Animal & Grassland Research and Innovation Centre, Mellows Campus, Athenry, Co. Galway, - - 2014
The Finnish Landrace (Finnsheep) is a well known high-prolificacy sheep breed and has been used in many countries as a source of genetic material to increase fecundity of local breeds. Analyses to date have indicated that mutations with a large effect on ovulation rate are not responsible for the exceptional ...
van den Broek Ingrid V F IV Epidemiology & Surveillance Unit, Centre for Infectious Disease Control, National Institute of Public Health and the Environment (RIVM), P.O. Box 1 (75), 3720 BA Bilthoven, The - - 2014
Background. Chlamydia infections often follow an asymptomatic course but may damage the reproductive tract. Chlamydia antibodies in serum are used as markers for past infections and can relate to tubal pathology and infertility. This "proof of principle" study aimed to assess whether Chlamydia antibodies are detectable in easier to obtain, ...
Gebrie Higemengist A - - 2014
No study has been carried out to assess the blood lead levels of workers or the contribution of common workplace practices to lead exposure in Ethiopia. This study was carried out to assess the blood lead levels of female and male laborers in the construction sector in Jimma town, Ethiopia. ...
Damous Luciana Lamarão LL Gynecology Division, Department of Obstetrics and Gynecology, Laboratory of Structural and Molecular Gynecology (LIM-58), Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil. - - 2014
Cryopreservation of the ovarian tissue has shown promising results. However, there remain controversial issues such as the short half-life of grafts. In this aspect, there are some evidences that preconditioning the ovarian tissue before transplantation is beneficial. To determine the effect of hypoxic preconditioning in vitro on ovarian tissue prior ...
< 35 36 37 38 39 40 41 42 43 44 45 >
Recent Searches

Search Terms in Title