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Song Kwang Hoon - - 2014
Sho-saiko-to (SST) (also known as so-shi-ho-tang or xiao-chai-hu-tang) has been widely prescribed for chronic liver diseases in traditional Oriental medicine. Despite the substantial amount of clinical evidence for SST, its molecular mechanism has not been clearly identified at a genome-wide level. By using a microarray, we analyzed the temporal changes ...
Gori Tommaso T Department of Cardiology, University Medical Center of Mainz, Germany; Department of Cardiology, Spedali Riuniti di Bergamo, Italy. Electronic address: - - 2014
Niola Raffaella R UOSC di Radiologia Vascolare ed Interventistica AORN Cardarelli Napoli, Naples, - - 2014
The aim of this study was to evaluate the efficacy and the safety of selective uterine artery embolisation in patients with a high risk of haemorrhage due to obstetric issues. We retrospectively reviewed the angiographic examinations of 63 patients (average age ± SD, 32.6 years ± 4.8), affected by an obstetric disease with a high ...
Ando Yuichi Y Nagoya University Hospital, Nagoya, - - 2014
Buparlisib (BKM120) is an oral pan-phosphatidylinositol 3-kinase inhibitor, targeting all four isoforms of class I PI3K (α, β, γ, and δ). This open-label, Phase I, dose-escalation study was conducted to determine the maximum tolerated dose of continuous daily buparlisib in Japanese patients with advanced solid tumors. Secondary objectives included safety ...
Harkins April L AL Department of Chemistry, Marquette University, P. O. Box 1881, Milwaukee, Wisconsin, - - 2014
Chitosan (CS), a polysaccharide derived from chitin, the second most abundant polysaccharide, is widely used in the medical world because of its natural and nontoxic properties and its innate ability for antibacterial and hemostasis effects. In this study, the novel composites containing CS and cellulose (CEL) (i.e., [CEL + CS]), which we ...
Anderson Assaf Y AY Department of Chemistry, Center for Nanotechnology & Advanced Materials, Bar Ilan University , 52900 Ramat Gan, - - 2014
All-oxide-based photovoltaics (PVs) encompass the potential for extremely low cost solar cells, provided they can obtain an order of magnitude improvement in their power conversion efficiencies. To achieve this goal, we perform a combinatorial materials study of metal oxide based light absorbers, charge transporters, junctions between them, and PV devices. ...
Zhou Zhan Z Key Laboratory of Theoretical Chemistry of Environment, Ministry of Education, School of Chemistry and Environment, South China Normal University , Guangzhou 510006, P. R. - - 2014
A novel polydentate type ligand derived from N(2),N(6)-bis(4,4-diethoxy-9-oxo-3-oxa-8,10-diaza-4-siladodecan-12-yl)pyridine-2,6-dicarboxamide (L) has been designed, and it played essential roles in the assembly of new organic-inorganic functional materials. First, its multiple amide groups would coordinate to lanthanide ions firmly and transfer the absorbed energy to both Eu(III) and Tb(III) simultaneously. Second, the hydrogen-bond ...
Pani Nihar Ranjan NR Department of Pharmaceutics, Gayatri College of Pharmacy, Sambalpur, Odisha, India. Electronic address: - - 2014
Glipizide (GPZ) has been widely used in the treatment of type-2 diabetics as insulin secretogague. Multiunit chitosan based GPZ floating microspheres was prepared by ionotropic gelation method for gastroretentive delivery using sodiumtripolyphosphate as cross-linking agent. Pharmacokinetic study of microspheres was done in rabbit and plasma samples were analyzed by a ...
Martinez Marissa R MR 1University of - - 2014
The factors that contribute to pulmonary embolism (PE), a potentially fatal complication of deep vein thrombosis (DVT), remain poorly understood. Whereas fibrin clot structure and functional properties have been implicated in the pathology of venous thromboembolism and the risk for cardiovascular complications, their significance in PE remain incomplete. Therefore we ...
Silbernagel Guenther G Department of Angiology, Swiss Cardiovascular Center, Inselspital, University of Bern, Bern, Switzerland; Division of Endocrinology, Diabetology, Nephrology, Vascular Disease, and Clinical Chemistry, Department of Internal Medicine, University of Tübingen, Tübingen, Germany. Electronic address: - - 2014
There is broad evidence that lowering low-density lipoprotein (LDL) cholesterol will reduce cardiovascular risk. However, in patients on maintenance hemodialysis treatment, lowering LDL cholesterol is not as effective in preventing cardiovascular complications as in the general population. Cholesterol is either endogenously synthesized or absorbed from the intestine. It has been ...
Sharma Jaswinder - - 2014
Mitochondrial dysfunction has been linked to neuronal death and a wide array of neurodegenerative diseases. Previously, we have shown sex differences in mitochondria-mediated cell death pathways following hypoxia-ischemia. However, the role of mitochondrial biogenesis in hypoxic-ischemic brain injury between male vs. female has not been studied yet. Primary cerebellar granule ...
Yen Yi-Chen - - 2014
MicroRNAs (miRNAs), small noncoding RNA molecules can function as oncogenes or tumor suppressors in tumorigenesis. Oral squamous cell carcinoma (OSCC) is one of the most prevalent cancers worldwide with a 5-year survival rate of approximately 50%. The expression of microRNA-99a (miR-99a) in OSCC tissues and cell lines was investigated using ...
Nogueras-Ortiz Carlos J CJ Department of Biology, University of Puerto Rico - Río Piedras Campus San Juan, PR, USA ; Department of Chemistry, University of Puerto Rico - Río Piedras Campus San Juan, PR, - - 2014
Molecular diagnostic tools with non-invasive properties that allow detection of pathological events in Alzheimer's disease (AD) and other neurodegenerative tauopathies are essential for the development of therapeutics. Several diagnostic strategies based on the identification of biomarkers have been proposed. However, its specificity among neurodegenerative disorders is disputable as the association ...
Haddad Ella H - - 2014
In vitro studies rank walnuts (Juglans regia) among the plant foods high in antioxidant capacity, but whether the active constituents of walnuts are bioavailable to humans remains to be determined. The intention of this study was to examine the acute effects of consuming walnuts compared to refined fat on meal ...
Zhou Rong - - 2014
Nonlinear transmission parameters of monolayer graphene at 1645 nm were obtained. Based on the monolayer graphene saturable absorber, a 1532 nm LD pumped 1645 nm passively Q-switched Er:YAG laser was demonstrated. Under the pump power of 20.8 W, a 1645 nm Q-switched pulse with FWHM of 0.13 nm (without the use of etalon) and energy of ...
Tsai Dung-Ying DY Department of Chemistry, National Central University, Chung-Li 320, - - 2014
A simple and effective method for the rapid determination of five salicylate and benzophenone-type UV absorbing substances in marketed fish is described. The method involves the use of matrix solid-phase dispersion (MSPD) prior to their determination by on-line silylation gas chromatography tandem mass spectrometry (GC-MS/MS). The parameters that affect the ...
Liu Xi - - 2014
In Chinese traditional medicine, Agrimonia pilosa Ledeb (APL) exhibits great effect on treatment of type 2 diabetes mellitus (T2DM), however its mechanism is still unknown. Considering that T2DM are correlated with postprandial hyperglycemia and oxidative stress, we investigated the alpha-glucosidase inhibitory activity and the antioxidant activity of flavonoid compound (FC) ...
Faggion Clovis Mariano CM Jr Periodontist, Department of Periodontology, Faculty of Dentistry, University of Münster, Waldeyerstrasse 30, 48149 Münster, Germany. Electronic address: - - 2014
Absorbable collagen membranes for periodontal regeneration: A systematic review. Stoecklin-Wasmer C, Rutjes AWS, da Costa BR, Salvi GE, Jüni P, Sculean A. J Dent Res 2013;92(9):773-81. Clovis Mariano Faggion Jr., DDS, Dr med dent, PD PURPOSE/QUESTION: The authors conducted a systematic review (SR) to assess the clinical, radiographic, and safety outcomes ...
Ding Ran R State Key Laboratory of Natural Medicines, PR China; School of Life Science and Technology China Pharmaceutical University, Nanjing 210009, PR - - 2014
YCP, an α-glucan from the mycelium of marine filamentous fungus Phoma herbarum YS4108, has great antitumor potential via enhancement of host immune through Toll-like receptor (TLR) 2 and TLR4 signaling. In the current study, YCP was coupled to EAH Sepharose 4B agarose beads to prepare the YCP-Sepharose affinity absorbent using ...
Lu Kun K Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, - - 2014
The human intestine is host to an enormously complex, diverse, and vast microbial community, the gut microbiota. The gut microbiome plays a profound role in metabolic processing, energy production, immune and cognitive development, epithelial homeostasis, and so forth. However, the composition and diversity of the gut microbiome can be readily ...
Rzymski Piotr P Department of Biology and Environmental Protection, Poznan University of Medical Sciences, Rokietnicka 8, 60-806, Poznań, Poland, - - 2014
Urbanization can considerably affect water reservoirs by, inter alia, input, and accumulation of contaminants including metals. Located in the course of River Cybina, Maltański Reservoir (Western Poland) is an artificial shallow water body built for recreation and sport purposes which undergoes restoration treatment (drainage) every 4 years. In the present study, ...
Nordin Mohd-Al-Faisal MA Department of Oral Biology and Biomedical Sciences, Faculty of Dentistry, University of Malaya, Kuala Lumpur, - - 2014
Candida species have been associated with the emergence of strains resistant to selected antifungal agents. Plant products have been used traditionally as alternative medicine to ease mucosal fungal infections. This study aimed to investigate the effects of Piper betle extract on the growth profile and the ultrastructure of commonly isolated ...
Sun Yingnan Y Hunan Key Laboratory of Nonresolving Inflammation and Cancer, Changsha, Hunan, People's Republic of - - 2014
The 5-year survival rate for colorectal cancer is approximately 55 % because of its invasion and metastasis. The epithelial-mesenchymal transition (EMT) is one of the well-defined processes during the invasion and distant metastasis of primary epithelial tumors. miR-429, a member of the miR-200 family of microRNAs, was previously shown to inhibit ...
Tang Bo - - 2014
T cells orchestrate joint inflammation in rheumatoid arthritis (RA), yet they are difficult to study due to the small numbers of antigen-specific cells. The goal of this study was to characterize a new humanized model of autoimmune arthritis and to describe the phenotypic and functional changes that occur in autoimmune ...
Inokuma Yasuhide Y Department of Applied Chemistry, School of Engineering, The University of Tokyo, Tokyo, - - 2014
We recently reported a new method for single-crystal X-ray diffraction (SCD) analysis that does not require the crystallization of the target compound. In this 'crystal-free' crystallography, a tiny crystal of a porous complex is soaked in the solution of the target guest. The guest molecules are absorbed and oriented in ...
Fratianni Florinda F Istituto di Scienze dell'Alimentazione, Consiglio nazionale delle Ricerche, ISA-CNR , Via Roma 64, 83100 Avellino , Italy - - 2014
Abstract The probiotic yeast, Saccharomyces cerevisiae boulardii, was microencapsulated in a mixture of alginate-inulin-xanthan gum, and its ability to grow in berry juice and survive 4 weeks of storage at 4 °C was determined. Exposure of the yeast in these forms to artificial gastrointestinal conditions was also assessed. Encapsulation significantly enhanced ...
Huh Joonsuk - - 2014
Phototrophic organisms such as plants, photosynthetic bacteria and algae use microscopic complexes of pigment molecules to absorb sunlight. Within the light-harvesting complexes, which frequently have several functional and structural subunits, the energy is transferred in the form of molecular excitations with very high efficiency. Green sulfur bacteria are considered to ...
Erez Yuval - - 2014
Steady-state and time-resolved emission techniques were employed to study the acid-base effects on the UV-Vis spectrum of curcumin in several organic solvents. The fluorescence-decay rate of curcumin increases with increasing acid concentration in all the solvents studied. In methanol and ethanol solutions containing about 1M HCl, the short-wavelength fluorescence (λ<560nm) ...
Schiborr Christina C Institute of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, - - 2014
Curcumin revealed various health-beneficial properties in numerous studies. However its bioavailability is low due to its limited intestinal uptake and rapid metabolism. The aim of our project was to develop novel curcumin formulations with improved oral bioavailability and to study their safety as well as potential sex-differences. In this crossover ...
Pandey Pramod P Chemical Laboratory, Department of Chemistry, DSB Campus, Kumaun University, Nainital, 263002, Uttarakhand, India, - - 2014
In the present work, surface interaction of L-alanine (L-ala) has been investigated on hematite (α-Fe2O3), an abundant mineral on Mars, as a function of time (5 min-48 h), pH (4.0 and 6.20 ± 0.10) and concentration (1 × 10(-3) M-10 × 10(-3) M) with optical absorbance and energy-dispersive spectroscopy (EDS). Adsorption parameters (XM and KL) were calculated from Langmuir adsorption ...
Chen Qian Q Institute of Functional Nano & Soft Materials (FUNSOM) & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu 215123, - - 2014
In this work, we develop a multifunctional nano-platform by coating upconversion nanoparticles (UCNPs) with bovine serum albumin (BSA), obtaining UCNP@BSA nanoparticles with great solubility and stability in physiological environments. Two types of dye molecules, including a photosensitizer, Rose Bengal (RB), and an NIR-absorbing dye, IR825, can be simultaneously loaded into ...
Adalja Amesh A AA UPMC Center for Health Security, Baltimore, MD; Department of Emergency Medicine, Department of Critical Care Medicine, and Division of Infectious Diseases, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA. Electronic address: - - 2014
Hospital evacuations have myriad effects on all elements of the health care system. We seek to (1) examine the effect of patient surge on hospitals that received patients from evacuating hospitals in New York City during Hurricane Sandy; (2) describe operational challenges those hospitals faced pre- and poststorm; and (3) ...
Ritson J P JP Grantham Institute for Climate Change, Imperial College London, South Kensington, London SW7 2AZ, UK; Department of Civil and Environmental Engineering, Imperial College London, South Kensington, London, SW7 2AZ, UK. Electronic address: - - 2014
Climate change in the UK is expected to cause increases in temperatures, altered precipitation patterns and more frequent and extreme weather events. In this review we discuss climate effects on dissolved organic matter (DOM), how altered DOM and water physico-chemical properties will affect treatment processes and assess the utility of ...
Nepal Ashwini Kumar - - 2014
Zinc deficiency is a major public health problem in many developing countries including Nepal. The present study was designed to assess the prevalence of zinc deficiency and to study the association of zinc deficiency with anthropometric and socio-demographic variables, in school children of Eastern Nepal. This cross-sectional study included total ...
Ogawa Yukari - - 2014
Although most reports describing patients infected with methicillin-resistant Staphylococcus aureus enterocolitis have been published in Japan, this concept remains a matter of debate and diagnostic criteria have not yet been defined. The general status of a 74-year-old Japanese man referred to our hospital (day 1) with severe community-acquired pneumococcal pneumonia ...
Lai Xihu - - 2014
Excessive apoptosis of beta-cell is closely related to diabetes mellitus. Chronic exposure to high glucose causes beta-cell dysfunction and apoptosis in diabetes. Thorn grape (Vitis davidii Foex.) has been used to treat diabetes in Traditional Chinese medicine for many years. In our previous research, thorn grape seeds oil (TGSO) showed ...
Su Dongxiao - - 2014
The phenolic contents and antioxidant activities of fruits could be underestimated if the bound phenolic compounds are not considered. In the present study, the extraction efficiencies of various solvents were investigated in terms of the total content of the free and bound phenolic compounds, as well as the phenolic profiles ...
Kim Yoon-Ha - - 2014
Silicon (Si) application has been known to enhance the tolerance of plants against abiotic stresses. However, the protective mechanism of Si under heavy metals contamination is poorly understood. The aim of this study was to assess the role of Si in counteracting toxicity due to cadmium (Cd) and copper (Cu) ...
Yang Mingli - - 2014
The majority of patients with acute myelogenous leukemia (AML) still die of their disease. In order to improve survival rates in AML patients, new strategies are necessary to discover biomarkers for the detection and targeted therapy of AML. One of the advantages of the aptamer-based technology is the unique cell-based ...
Diamantidis Clarissa J - - 2014
Several reports show that patients with chronic disease who are empowered with information technology (IT) tools for monitoring, training and self-management have improved outcomes, however there are few such applications employed in kidney disease. This review explores the current and potential uses of health IT platforms to advance kidney disease ...
Feng Xuyang - - 2014
Autophagy is an essential process for breaking down macromolecules and aged/damaged cellular organelles to maintain cellular energy balance and cellular nutritional status. The idea that autophagy regulates lipid metabolism is an emerging concept with important implications for atherosclerosis. However, the potential role of autophagy and its relationship with lipid metabolism ...
Ryu Jae Yong - - 2014
Adverse environmental conditions severely influence various aspects of plant growth and developmental processes, causing worldwide reduction of crop yields. The C-repeat binding factors (CBFs) are critical transcription factors constituting the gene regulatory network that mediates the acclimation process to low temperatures. They regulate a large number of cold-responsive genes, including ...
Benke Andreas - - 2014
Iron (Fe) deficiency symptoms in maize (Zea mays subsp. mays) express as leaf chlorosis, growth retardation, as well as yield reduction and are typically observed when plants grow in calcareous soils at alkaline pH. To improve our understanding of genotypical variability in the tolerance to Fe deficiency-induced chlorosis, the objectives ...
Marini Guillermo - - 2014
Streptococcus pneumoniae (S. pneumoniae) causes several serious diseases including pneumonia, septicemia and meningitis. The World Health Organization estimates that streptococcal pneumonia is the cause of approximately 1.9 million deaths of children under five years of age each year. The large number of serotypes underlying the disease spectrum, which would be ...
Markert Benno - - 2014
Transketolase (TKT) is a key enzyme of the pentose phosphate pathway (PPP), the Calvin cycle and the ribulose monophosphate (RuMP) cycle. Bacillus methanolicus is a facultative RuMP pathway methylotroph. B. methanolicus MGA3 harbors two genes putatively coding for TKTs; one located on the chromosome (tktC) and one located on the ...
Lepage Aurélie - - 2014
Immune responses are generally impaired in aged mammals. T cells have been extensively studied in this context due to the initial discovery of their reduced proliferative capacity with aging. The decreased responses involve altered signaling events associated with the early steps of T cell activation. The underlying causes of these ...
Korsholm Marie E - - 2014
MRI-only radiotherapy will eliminate the systematic registration errors introduced when transferring MRI information to the CT. However, challenges concerning the missing information on electron density, necessary for dose calculation and patient setup on bony anatomy are introduced. This study presents a possible statistical approach to evaluate, if deviations based on ...
Beaudeau Pascal P Harvard School of Public Health, Boston, MA 02215, USA. Electronic address: - - 2014
We used a Poisson regression to compare daily hospital admissions of elderly people for acute gastrointestinal illness in Boston against daily variations in drinking water quality over an 11-year period, controlling for weather, seasonality and time trends. The Massachusetts Water Resources Authority (MWRA), which provides non-filtered water to 1.5 million ...
Praena J J Universidad de Sevilla, Spain; Centro Nacional de Aceleradores (US-JA-CSIC), Seville, Spain. Electronic address: - - 2014
(33)S is a stable isotope of sulfur for which the emission of an α-particle is the dominant exit channel for neutron-induced reactions. In this work the enhancement of both the absorbed and the equivalent biologically weighted dose in a BNCT treatment with 13.5keV neutrons, due to the presence of (33)S, ...
Burstyn Igor - - 2014
Electronic cigarettes (e-cigarettes) are generally recognized as a safer alternative to combusted tobacco products, but there are conflicting claims about the degree to which these products warrant concern for the health of the vapers (e-cigarette users). This paper reviews available data on chemistry of aerosols and liquids of electronic cigarettes ...
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