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Zhang Wu W Department of Adiotherapy, The Third Affiliated Hospital, Wenzhou Medical College, Wenzhou, - - 2014
We tried to investigate the expression characteristics of KAI1, a suppressor of wide-spectrum tumor metastasis, and vascular endothelial growth factor (VEGF), the most common angiogenesis factor, and then to analyze their diagnostic value for hepatocellular carcinoma (HCC). The protein and mRNA expression levels of KAI1 or VEGF in HCC tissues ...
Messadi Diana V DV Section of Oral Medicine and Orofacial Pain, Division of Oral Biology and Medicine, School of Dentistry, University of California at Los Angeles, Los Angeles, - - 2014
Optical spectroscopy devices are being developed and tested for the screening and diagnosis of oral precancer and cancer lesions. This study reports a device that uses white light for detection of suspicious lesions and green-amber light at 545 nm that detect tissue vascularity on patients with several suspicious oral lesions. The ...
Edirisinghe P A S PA Department of Forensic Medicine, Faculty of Medicine, University of Kelaniya, Thalagolla Road, Ragama, Sri Lanka. Electronic address: - - 2014
Vulnerable Road Users defined as people at risk in traffic due to absence of an outside protective shield to absorb energy during a collision are mainly pedestrians, bicycle riders and motor cyclists. In low income countries, deaths of VRUs outnumber vehicular drivers and occupants. A forensic pathologist not only reports ...
Nastasi Francesco F Dipartimento di Scienze Chimiche, Università di Messina, and Centro Interuniversitario per la Conversione Chimica dell'Energia Solare (Fotosintesi Artificiale, SOLAR-CHEM), 98166 Messina, Italy. - - 2014
A Bodipy species bearing an acetyl-acetonate (acac) group, , has been prepared from a blue absorbing borondipyrromethene core bearing gallate substituted paraffin chains. Compound chelates a Pt(ii) center having an orthometalated 2-phenyl-pyridine anion (ppy) as an additional ligand, giving rise to a new bichromophoric Pt(ii)-Bodipy species, . The absorption spectra, ...
Denniff Philip - - 2014
Volumetric Absorbtive Micro Sampling is a novel approach to obtaining a dried blood sample for quantitative bioanalysis that overcomes the area bias and sample homogeneity issues associated with conventional DBS when a sub-punch is taken from the sample. The VAMS sampler absorbs a fixed volume of blood (~10 µL) in ...
Vazquez-Mena Oscar - - 2014
The optical transparency and high electron mobility of graphene make it an attractive material for photovoltaics. We present a field-effect solar cell using graphene to form a tunable junction barrier with an Earth-abundant and low cost zinc phosphide (Zn3P2) thin-film light absorber. Adding a semi-transparent top electrostatic gate allows for ...
Enomoto Gen G University of Tokyo, - - 2014
Cyanobacteria have unique photoreceptors, cyanobacteriochromes, that show diverse spectral properties to sense near-UV/visible lights. Certain cyanobacteriochromes have been shown to regulate cellular phototaxis or chromatic acclimation of photosynthetic pigments. Some cyanobacteriochromes have output domains involved in a bacterial signaling using a second messenger cyclic dimeric GMP (c-di-GMP), but its role ...
Magro Daniéla Oliveira - - 2014
Constipation is a frequent complaint and the combination of a prebiotic and probiotics could have a potentially synergic effect on the intestinal transit. The present study therefore aims to investigate the combination of polydextrose (Litesse(R)), L. acidophilus NCFM(R) and B. lactis HN019 in a yogurt on intestinal transit in subjects ...
Furchi Marco M - - 2014
Semiconductor heterostructures form the cornerstone of many electronic and optoelectronic devices and are traditionally fabricated using epitaxial growth techniques. More recently, heterostructures have also been obtained by vertical stacking of two-dimensional crystals, such as graphene and related two-dimensional materials. These layered designer materials are held together by van der Waals ...
Cha Hwa Jun HJ Korea Institute for Skin and Clinical Sciences, Konkuk University, Seoul 143‑701, Republic of - - 2014
Ultraviolet (UV) radiation impairs intracellular functions by directly damaging DNA and by indirectly generating reactive oxygen species (ROS), which induce cell cycle arrest and apoptosis. UV radiation can also alter gene expression profiles, including those of mRNA and microRNA (miRNA). The effects of UV radiation on cellular functions and gene ...
Hope Elyse A EA University of - - 2014
The ability of yeast to form biofilms contributes to better survival under stressful conditions. We see the impact of yeast biofilms and "flocs" (clumps) in human health and industry, where forming clumps enables yeast to act as a natural filter in brewing and forming biofilms enables yeast to remain virulent ...
Sakuma Shinji S Faculty of Pharmaceutical Sciences, Setsunan - - 2014
Thomsen-Friedenreich (TF) antigen belongs to the mucin-type tumor-associated carbohydrate antigen. Notably, TF antigen is overexpressed in colorectal cancer (CRC) but is rarely expressed in normal colonic tissue. Increased TF antigen expression is associated with tumor invasion and metastasis. In this work, we sought to validate a novel nanobeacon for imaging ...
Koutelidakis Antonios E AE Unit of Human Nutrition, Laboratory of Food Chemistry and Analysis, Department of Food Science and Human Nutrition, Agricultural University of Athens , Iera Odos, Greece - - 2014
Abstract The hypothesis that iron and fat in the diet may affect green tea extract (GTE) bioactivity, in particular antioxidant capacity and gene expression, was proposed and tested in mice. Thirty mice were randomly assigned to have for 37 days free access to standard or high-fat diets with or without ...
Dreher Maureen L ML Division of Solid & Fluid Mechanics, US Food & Drug Administration, Center for Devices and Radiological Health, Office of Science and Engineering Laboratories, Silver Spring, Maryland, - - 2014
While absorbable materials and medical devices primarily degrade through hydrolysis, their degradation kinetics are sensitive to environmental conditions, including temperature, pH, and mechanical loading. While there is some consistent information in the literature suggesting that strain controlled loading accelerates strength loss, there is much more limited information on the interaction ...
Tuna Deniz - - 2014
Kynurenines are UV filters found in the human ocular lens which protect the retina from radiation damage. We report on ab initio investigations of the photochemistry of the cis and trans conformers of kynurenine and of an intramolecularly hydrogen-bonded conformer of 3-hydroxykynurenine O-β-D-glucoside. We have explored the excited-state reaction paths ...
Kim Hajin H Department of Molecular Science and Technology, Ajou University, 206 World cup-ro, Yeongtong-gu, Suwon 443-749, South - - 2014
In this study, the concept of autoinhibition, a mechanism of protein activity regulation, was applied to the design and engineering of a β-lactamase zymogen. Using this zymogen, a sensitive protease assay method was developed in which activation of the zymogen by proteases produces an amplified absorbance signal. The approach reported ...
Chalret du Rieu Quentin Q EA4553, Univ. Toulouse III Paul Sabatier, 31000, Toulouse, - - 2014
First, to evaluate the peritoneal (IP), plasma ultrafiltrated (UF) and protein-bound (B) pharmacokinetics (PK) of oxaliplatin after intraperitoneal hyperthermic chemoperfusion (HIPEC) following cytoreductive surgery. Second, to evaluate the relationship between oxaliplatin exposure and observed toxicity. IP, UF, and B concentrations from 75 patients treated by 30-min oxaliplatin-based HIPEC procedures were ...
Ortega Francisco José - - 2014
Contaminants in water streams -in the form of oily/organic phases or nanoparticles- affect a large variety of activities, from laboratory practice up to environmental systems. To date, a large number of materials for the absorption and retention of these pollutants have been developed. Such materials, however, rarely conjugate high oil ...
Freddo Angelo Luiz AL 1 School of Dentistry, Universidade Federal do Rio Grande do Sul , Porto Alegre, Brazil - - 2014
Abstract Objective: This study aimed to understand the action of masticatory forces on an implant virtually introduced into the sheep mandible after distraction osteogenesis and low-level laser therapy (LLLT) by using finite element analysis. Background data: Distraction osteogenesis as an alternative for bone reconstruction that may be used in the ...
Baek Seung-Wook SW Department of Electronics and Computer Engineering, Hanyang University, Seoul 133-791, Republic of Korea. - - 2014
We found that Cd0.5Zn0.5S-ZnS core (4.2 nm in diameter)-shell (1.2 nm in thickness) quantum dots (QDs) demonstrated a typical energy-down-shift (2.76-4.96 → 2.81 eV), which absorb ultra-violet (UV) light (250-450 nm in wavelength) and emit blue visible light (∼442 nm in wavelength). They showed the quantum yield of ∼80% and ...
Brittenham Gary M GM From the Human Nutrition Laboratory, Institute of Food, Nutrition and Health, ETH Zürich, Zürich, Switzerland (IE, JTF, CZ, MA, and RFH); the Intrinsic LifeSciences LLC, La Jolla, CA (MEW); and the Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, NY - - 2014
After the oral administration of iron, the production of circulating non-transferrin-bound iron may contribute to an increased risk of illness in malaria-endemic areas that lack effective medical services.OBJECTIVE: In healthy women with a range of body iron stores, we aimed to determine effects on the production of circulating non-transferrin-bound iron ...
Létourneau-Montminy M P MP Agriculture and Agri-Food Canada, Dairy and Swine Research and Development Centre, Sherbrooke, QC, J1M 1Z3, Canada Actual address: Département des Sciences Animales, Laval University Quebec City, QC, G1V 0A6, - - 2014
Improving dietary P utilization without modifying pig performance is crucial for production sustainability. A feeding program comprising with three 28-day phases (20 to 40, 40 to 70 and 70 to 100 kg) was used to feed 72 pigs with an initial body weight of 20 kg. The ability of the ...
Hens Bart B Drug Delivery & Disposition, KU Leuven, Gasthuisberg O&N 2, Herestraat 49, Box 921, 3000 Leuven, - - 2014
The purpose of this study was to explore the transfer of drug solutions from stomach to small intestine and its impact on intraluminal drug concentrations in humans. The collected intraluminal data were used as reference to evaluate simulations of gastrointestinal transfer currently implemented in different in vitro and in silico ...
Penduka Dambudzo - - 2014
BackgroundListeriosis is a fatal disease caused by pathogenic Listeria bacteria and it is most prevalent in immune-compromised individuals. The increase in numbers of immune-compromised individuals against a background of Listeria antibiotic resistance, limits listeriosis treatment options. This therefore calls for research into substitute treatments, of which, medicinal plants derived compounds ...
Yang Tai-Hua - - 2014
The treatment of trigger finger so far has heavily relied on clinicians' evaluations for the severity of patients' symptoms and the functionality of affected fingers. However, there is still a lack of pathological evidence supporting the criteria of clinical evaluations. This study's aim was to correlate clinical classification and pathological ...
Pham Ba - - 2014
The concept of early health technology assessment, discussed well over a decade, has now been collaboratively implemented by industry, government, and academia to select and expedite the development of emerging technologies that may address the needs of patients and health systems. Early economic evaluation is essential to assess the value ...
Wang Wang - - 2014
Monocytes and T cells are two major subpopulations of peripheral blood mononuclear cells (PBMC) and play an essential role in the innate and adaptive immune systems. Different members of the galectin family show multiple and distinct regulatory effects on different cell types. Previous studies have demonstrated that the galectin from ...
Fathi M R MR Department of Chemistry, College of Science, Shahid Chamran University, P.O.Box 6135743337, Ahvaz, - - 2014
The objective of this study was to assess the suitability and efficiency of corn stalk (CS) for the removal of diazo dye Direct Red 23 (DR23) from aqueous solutions. The effect of different variables in the batch method as a function of solution pH, contact time, initial dye concentration, CS ...
Lisi Lucia - - 2014
Increased activation of mammalian target of rapamycin (mTOR) is observed in numerous human cancers. Recent studies on the glioma kinome have identified several deregulated pathways that converge and activate mTOR. The available evidence on the role of microglia in CNS cancers would suggest a dual role, a tumoricidal role and ...
Kang Mi-Hye MH Department of Food and Life Science, Pukyong National University, Nam-gu, Busan 608-737, Republic of - - 2014
Phloroglucinol is a polyphenolic compound that is used to treat and prevent several human diseases, as it exerts beneficial biological activities, including anti-oxidant, anti‑inflammatory and anticancer properties. The aim of the present study was to investigate the effects of phloroglucinol on apoptotic signaling pathways in HT-29 colon cancer cells. The ...
Li Jianping J Department of Urology, The Second Affiliated Hospital of Medical College, Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. - - 2014
Carcinoma progression is associated with the loss of epithelial features and the acquisition of a mesenchymal phenotype, a process known as epithelial‑mesenchymal transition (EMT). Resveratrol, a natural polyphenolic compound found in grapes, berries and peanuts, has a wide range of pharmacological properties, including anti‑tumor metastasis properties. The underlying mechanism through ...
Tanackovic Vanja V Department of Plant and Environmental Sciences, University of Copenhagen, Copenhagen, DK-1871, - - 2014
Brachypodium distachyon is a non-domesticated cereal. Nonetheless, Brachypodium was recently introduced as a model plant for temperate cereals. This study compares grain starch metabolism in Brachypodium and barley (Hordeum vulgare). In Brachypodium, we identified and annotated 28 genes involved in starch metabolism and identified important motifs including transit peptides and ...
Hilbert Ghislaine G INRA, ISVV, UMR 1287 EGFV, 33140 Villenave d'Ornon, - - 2015
The flavonol profiles of grape berry skins were analysed in order to assess phenotypic variation between six grapevines belonging to six different species: Vitis vinifera, Vitiscandicans, Vitischampinii, Vitisamurensis, Vitiscinerea and Vitisdoaniana. High-performance liquid chromatography coupled to mass spectrometry (LC-MS) and NMR spectrometry (LC-NMR) were used to separate and identify the ...
Roskopf Claudia C CC Klinikum der Universität München, Medizinische Klinik und Poliklinik IV, Haematology/Oncology, Munich, - - 2014
Triplebody 19-3-19, an antibody-derived protein, carries three single chain fragment variable domains in tandem in a single polypeptide chain. 19-3-19 binds CD19-bearing lymphoid cells via its two distal domains and primary T cells via its CD3-targeting central domain in an antigen-specific manner. Here, malignant B-lymphoid cell lines and primary cells ...
Gerlach Tobias T Animal Evolutionary Ecology Group, Faculty of Sciences, University of Tübingen, Auf der Morgenstelle 28 E, Tübingen, Germany - - 2014
Fluorescence enables the display of wavelengths that are absent in the natural environment, offering the potential to generate conspicuous colour contrasts. The marine fairy wrasse Cirrhilabrus solorensis displays prominent fluorescence in the deep red range (650-700 nm). This is remarkable because marine fishes are generally assumed to have poor sensitivity ...
Du Yunchen - - 2014
Core-shell composites, Fe3O4@C, with 500 nm Fe3O4 microspheres as cores have been successfully prepared through in situ polymerization of phenolic resin on the Fe3O4 surface and subsequent high-temperature carbonization. The thickness of carbon shell, from 20 nm to 70 nm, can be well controlled by modulating the weight ratio of ...
Nguyen William H - - 2014
2,2',7,7'-tetrakis-(N,N-di-p-methoxyphenylamine)-9,9'-spirobifluorene (spiro-OMeTAD), the prevalent organic hole transport material used in solid-state dye-sensitized solar cells and perovskite-absorber solar cells, relies on an uncontrolled oxidative process to reach appreciable conductivity. This work presents the use of a dicationic salt of spiro-OMeTAD, named spiro(TFSI)2, as a facile means of controllably increasing the conductivity ...
Xiao Manda M School of Chemistry, Monash University, Victoria 3800 - - 2014
Thin-film photovoltaics based on alkylammonium lead iodide perovskite light absorbers have recently emerged as a promising low-cost solar energy harvesting technology. To date, the perovskite layer in these efficient solar cells has generally been fabricated by either vapor deposition or a two-step sequential deposition process. We report that flat, uniform ...
Chen Po-Kai - - 2014
Under appropriate conditions, significant microwave-specific enhancement of the reaction rate of an organic chemical reaction can be observed. Specifically, the unimolecular Claisen rearrangement of allyl p nitrophenyl ether (ApNE) dissolved in naphthalene was studied under microwave heating and conventional convective (thermal) heating. Under conditions of constant microwave power, reaching a ...
Yong Yuan Y Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, 100049, P. R.China. zjgu@ihep.ac.cn zhaoyuliang@ihep.ac.cn - - 2014
We have developed a simple and efficient strategy to fabricate WS2 nanosheets with low toxicity and good water solubility via a liquid exfoliation method by using H2SO4 intercalation and ultrasonication. The as-prepared WS2 nanosheets were employed not only as an NIR absorbing agent for photothermal therapy (PTT) but also as ...
Rosana Michael R - - 2014
Thermally promoted Friedel-Crafts benzylation of arene solvents has been examined under both conventional convective heating with an oil bath and heating using microwave (MW) energy. Bulk solution temperatures - as measured by internal and external temperature probes and as defined by solvent reflux - were comparable in both sets of ...
Huang Shuling S Department of Pharmacy, Guangdong Pharmaceutical University, Higher Education Mega Center, Guangzhou 510006, - - 2014
In order to develop and compare mPEG-PLA micelles and mPEG-PLA/TPGS mixed micelles, with the intention to develop a highly efficient formulation for nimodipine (NIM), NIM-loaded micelles and mixed micelles were made and their pharmacokinetics were studied. Single factor experiments and orthogonal experiments were designed to optimize the final preparation process, ...
Whyte Michael P MP Center for Metabolic Bone Disease and Molecular Research, Shriners Hospital for Children; St. Louis, Missouri,, 63131USA; Division of Bone and Mineral Diseases, Washington University School of Medicine at Barnes-Jewish Hospital; St. Louis, Missouri,, 63110USA. Electronic address: - - 2014
Mendelian disorders of RANKL/OPG/RANK signaling feature the extremes of aberrant osteoclastogenesis and cause either osteopetrosis or rapid turnover skeletal disease. The patients with autosomal dominant accelerated bone remodeling have familial expansile osteolysis, early-onset Paget's disease of bone, expansile skeletal hyperphosphatasia, or panostotic expansile bone disease due to heterozygous 18-, 27-, ...
Lin Rong-Jyh RJ Department of Parasitology, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan. Electronic address: - - 2014
This study investigated the anthelmintic activity of gingerenone A, [6]-dehydrogingerdione, [4]-shogaol, 5-hydroxy-[6]-gingerol, [6]-shogaol, [6]-gingerol, [10]-shogaol, [10]-gingerol, hexahydrocurcumin, 3R, 5S-[6]-gingerdiol and 3S, 5S-[6]-gingerdiol, a constituent isolate from the roots of ginger, for the parasite Hymenolepis nana. The cestocidal activity or ability to halt spontaneous parasite movement (oscillation/peristalsis) in H. nana of ...
Ottosson Sandra - - 2014
Weight loss is a common problem in patients with Squamous Cell Carcinoma of the Head and Neck (SCCHN) treated with radiotherapy (RT). The aims of the present study were to determine if treated volume (TV), as a measure of the radiation dose burden, can predict weight loss in patients with ...
Huat Tee Jong - - 2014
There has been increasing interest recently in the plasticity of mesenchymal stem cells (MSCs) and their potential to differentiate into neural lineages. To unravel the roles and effects of different growth factors in the differentiation of MSCs into neural lineages, we have differentiated MSCs into neural lineages using different combinations ...
Frueh Florian S - - 2014
The combination of perforated diverticulitis in a lumbar hernia constitutes an extremely rare condition. We report a case of a 66 year old Caucasian woman presenting with perforated sigmoid diverticulitis localized in a lumbar hernia following iliac crest bone graft performed 18 years ago. Emergency treatment consisted of laparoscopic peritoneal ...
Lesnyak Vladimir - - 2014
We report the synthesis of alloyed quaternary and quinary nanocrystals based on copper chalcogenides, namely, copper zinc selenide-sulfide (CZSeS), copper tin selenide-sulfide (CTSeS), and copper zinc tin selenide-sulfide (CZTSeS) nanoplatelets (NPLs) (~20 nm wide) with tunable chemical composition. Our synthesis scheme consisted of two facile steps: i.e. the preparation of ...
Bizuayehu Teshome Tilahun TT Faculty of Aquaculture and Biosciences, University of Nordland, Bodø, - - 2014
microRNAs (miRNAs) are transcriptional and posttranscriptional regulators involved in nearly all known biological processes in distant eukaryotic clades. Their discovery and functional characterization have broadened our understanding of biological regulatory mechanisms in animals and plants. They show both evolutionary conserved and unique features across Metazoa. Here, we present the current ...
Wu Daoming D College of Resources and Environment, South China Agricultural University, Guangzhou 510642, - - 2014
Al-induced cell rigidity is one of the symptoms of Al toxicity, but the mechanism by which plants tolerate this toxicity is still unclear. In this study, we found that overexpression of OsPIN2, an auxin transporter gene, could alleviate Al-induced cell rigidity in rice root apices. A freeze-thawing experiment showed that ...
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