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Pennington Elliot C EC Boston Children's Hospital and Harvard Medical School, Boston, - - 2014
It is well established through randomized trials that oral antibiotics given with or without a mechanical bowel preparation (MBP) prior to colorectal procedures reduce complications, while MBP given alone provides no benefit. We aimed to characterize trends surrounding bowel preparation in children and determine whether contemporary practice is evidence-based. Retrospective ...
Wang Jin J Department of Neurology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Sir Run Run Shaw Institute of Clinical Medicine of Zhejiang University, Hangzhou, Zhejiang 310016, - - 2014
Subdural hematoma (SDH) is a common complication of spontaneous intracranial hypotension (SIH). To date, the management of SDH caused by SIH remains controversial. In this paper, we reviewed the clinical course of SDH in patients with SIH, and discuss the underlying mechanism and attributing factors for rapid resolution of subdural ...
Matikka H H Imaging Center, Kuopio University Hospital, Kuopio, - - 2014
Cone-beam computed tomography (CBCT) is a relatively new technique for imaging of extremities. It provides high-resolution images with lower effective dose compared to conventional CT. However following the ALARA principle, CBCT-imaging protocols and practices must also be optimised to minimize the dose absorbed by the patient as well as personnel. ...
Zamora D D Research Group Ciencia e Ingeniería del Agua y el Ambiente, Faculty of Engineering, Pontificia Universidad Javeriana, Carrera 7 No. 40-62, Bogotá, Colombia E-mail: - - 2014
Reliable estimations of the evolution of water quality parameters by using in situ technologies make it possible to follow the operation of a wastewater treatment plant (WWTP), as well as improving the understanding and control of the operation, especially in the detection of disturbances. However, ultraviolet (UV)-Vis sensors have to ...
Sarmento Sandra M SM Universidade Federal de Pernambuco, Departamento de Engenharia Química; Av. Prof. Artur de Sá, SN., Cidade Universitária, CEP: 50740-521, Recife, PE, Brazil E-mail: - - 2014
This work is concerned with the intrinsic reaction kinetic of the degradation of atrazine (ATZ) using H2O2-UVC. Experimental runs were carried out in annular photoreactor. The initial concentration of ATZ was 2.2 × 10(-2) mol m(-3) while the H2O2-ATZ molar ratio range was 0-578 mol H2O2 mol(-1) ATZ. The ATZ ...
Fromantin Isabelle I Institute Curie, Paris, France; - - 2014
Few studies have addressed the effects of dressings on malignant wounds. A 20-month (May 2010 to January 2011) descriptive, prospective cohort study was conducted by the Wound Care Unit of Institute Curie, Paris, France to evaluate the use of various local care procedures and characteristics of malignant wounds. Symptoms and ...
Ma Guancong G 1] Department of Physics, Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China - - 2014
An impedance-matched surface has the property that an incident wave generates no reflection. Here we demonstrate that by using a simple construction, an acoustically reflecting surface can acquire hybrid resonances and becomes impedance-matched to airborne sound at tunable frequencies, such that no reflection is generated. Each resonant cell of the ...
Niguès A A Institut Lumière Matière, UMR5306 Université Lyon 1-CNRS, 69622 Villeurbanne cedex, - - 2014
Friction at the nanoscale has revealed a wealth of behaviours that depart strongly from the long-standing macroscopic laws of Amontons-Coulomb. Here, by using a 'Christmas cracker'-type of system in which a multiwalled nanotube is torn apart between a quartz-tuning-fork-based atomic force microscope (TF-AFM) and a nanomanipulator, we compare the mechanical ...
Sadouki M M Faculté des Sciences et de la Technologie, Université de Khemis Miliana BP 44225 Ain Defla, - - 2014
Conventional acoustical methods for measuring the permeability or flow resistivity of a porous material require a priori estimation of the porosity. In this work, an acoustical method is presented in which a simplified expression (independent of both the frequency and porosity) for the transmitted waves at the Darcy's regime (low ...
Hoang Minh Tan MT Université Paris-Est, Laboratoire Modélisation et Simulation Multi Echelle, MSME UMR 8208 CNRS, 5 bd Descartes, 77454 Marne-la-Vallée, - - 2014
It is shown that three-dimensional periodic unit cells (3D PUC) representative of transport parameters involved in the description of long wavelength acoustic wave propagation and dissipation through real foam samples may also be used as a standpoint to estimate their macroscopic linear elastic properties. Application of the model yields quantitative ...
Randall Robert C RC Electroacoustic Research Laboratory, Advanced Technology and Manufacturing Center and Department of Electrical and Computer Engineering, University of Massachusetts Dartmouth, 151 Martine Street, Fall River, Massachusetts - - 2014
Velocity control feedback may be required for implementation in large underwater acoustic arrays to mitigate the effects of strong acoustic field coupling when specific beam pattern performance over a variety of operating conditions is desired. This paper presents an analysis of velocity control with piezoelectric loads using motional current monitoring ...
Biró Anna A Országos Kémiai Biztonsági Intézet Citogenetikai és Immunológiai Csoport Budapest Nagyvárad tér 2. - - 2014
Introduction: Kaqun-water contains a high amount of stable oxygen, which absorbed through the skin and intestinal tract, increases tissue oxygenation. Aim: The aim of the authors was to evaluate the effect of 21 days of Kaqun-water treatment on the immune parameters of healthy volunteers. Method: Subpopulations of lymphocytes were determined ...
Ahmad H - - 2014
A Q-switched dual-wavelength fiber laser with narrow channel spacing is proposed and demonstrated. The fiber laser is built around a 3 m long erbium doped fiber as the gain medium and a 10 cm long photonic crystal fiber (PCF) as the element used to generate the dual-wavelength output. The PCF has a ...
Remacha Clément - - 2014
We propose a tomographic method for point source inline holographic microscopy. By recording a set of holograms at different illumination angles, shadowing effects are eliminated resulting in three-dimensional images with the same precision at the micrometer-scale in all directions. The advantage of our tomographic approach is that it works for ...
Chen Ting-Wei - - 2014
This study presents a hybrid Q-switched Nd:LuVO<sub>4</sub> laser with an acousto-optic modulator (AOM) and a Cr<sup>4+</sup>:YAG saturable absorber. The importance of the modulation frequency of the AOM in this dual-loss modulation system is examined with two distinct observations: (1) the periodic-ramp pulse characteristics with the modulation frequency, and (2) the existence of ...
Shen Zhi-Yong ZY Department of General Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 201112, P.R. - - 2014
MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate the expression of targeted genes in a post-transcriptional manner. Increasing evidence indicates that miRNAs play important roles in cancer pathogenesis, including apoptosis, proliferation and differentiation, as oncogenes or tumor suppressors. Previously, miR-375 was shown to be involved in human gastric cancer, ...
Li Jun J Department of Rheumatology and Immunology, Shanghai Third People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 201999, P.R. - - 2014
The aim of the present study was to investigate the inhibitory effect of sodium houttuyfonate (SH) on synovial cell proliferation in vitro. Primary cells were obtained from the synovial tissue of a patient with rheumatoid arthritis (RA). The cells were divided into five treatment groups as follows: the control group ...
Stefan J J Chair of Pharmacology, Jagiellonian University, Medical College, Cracow, Poland. - - 2014
Chitosan is biocompatible polymer obtained from chitin, the building component of the crustacean shells. In this paper we make an attempt to review the current state of knowledge on some biological effects of chitosan in comparison with those of cationically modified chitosan, N-(2-hydroxypropyl)-3-trimethylammonium chitosan chloride (HTCC) that was recently synthetized ...
Qin Zai-Sheng ZS Department of Anesthesiology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. - - 2014
Hyperthermia not only directly induces cell injury of body tissues, but also causes the body to release large amounts of inflammatory mediators and cells with extensive biological activities to induce a systemic inflammatory response and immune dysfunction. Thus, hyperthermia causes systemic inflammatory response syndrome, aggravating injuries to various organs. This ...
Wang Kun K Department of Orthopedics, Affiliated Jinshan Hospital, Fudan University, Shanghai 201508, P.R. - - 2014
SUMOylation is a dynamic and reversible process. Several SUMO-specific proteases (SENPs) that remove SUMO from substrates have been shown to be amplified in a subset of cancers. SENP5 is required for cell division, as well as maintaining mitochondrial morphology and function. SENP5 has been reported to be predominantly localized to ...
Esquivel Carlos J CJ Department of Entomology, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, Ohio, United States of - - 2014
The consumption of a vertebrate blood meal by adult female mosquitoes is necessary for their reproduction, but it also presents significant physiological challenges to mosquito osmoregulation and metabolism. The renal (Malpighian) tubules of mosquitoes play critical roles in the initial processing of the blood meal by excreting excess water and ...
Yap Michelle Khai Khun MK CENAR and Department of Molecular Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, - - 2014
The optimization of snakebite management and the use of antivenom depend greatly on the knowledge of the venom's composition as well as its pharmacokinetics. To date, however, pharmacokinetic reports on cobra venoms and their toxins are still relatively limited. In the present study, we investigated the pharmacokinetics of Naja sumatrana ...
Lin Shengyun S Department of Hematology, The First Affiliated Hospital, Zhejiang Chinese Medical University, Hangzhou, Zhejiang 310006, P.R. - - 2014
The novel orally available inhibitor of the molecular chaperone heat shock protein 90 (Hsp90), BIIB021, induces the apoptosis of various types of tumor cell in vitro and in vivo. However, the effects and mechanisms of this agent on myelodysplastic syndrome (MDS) cell lines remain unknown. The aim of this study ...
Zhao Juan J School of Pharmaceutical Sciences, Jilin University, Changchun, Jilin 130021, P.R. China ; Department of Pathophysiology, Chengde Medical University, Chengde, Hebei 067000, P.R. - - 2014
The aim of the present study was to investigate the effects of urantide on the expression status of C-reactive protein (CRP) and the inflammatory cytokines monocyte chemotactic protein (MCP)-1 and transforming growth factor (TGF)-β in the aortas of rats with atherosclerosis (AS), and to identify its underlying mechanisms. The effects ...
Zhong Yi Y Department of Cardiology, The Affiliated Hospital of Luzhou Medical College, Luzhou, Sichuan 646000, P.R. - - 2014
The aim of the present study was to investigate the inhibitory effect of curcumin on tumor necrosis factor (TNF)-α-induced cell migration and matrix metalloproteinase (MMP)-2 expression and activity in rat vascular smooth muscle cells (VSMCs), in order to identify whether the effects are mediated by the nuclear factor (NF)-κB signaling ...
Huang Fang F Department of Nutrition and Health Care, School of Public Health, Fujian Medical University, Fuzhou, Fujian 350004, P.R. - - 2014
Although its mechanisms remain unidentified, resveratrol (trans-3,4',5-trihydroxystilbene; RES), which is an active, low molecular-weight compound, possesses a unique antitumor function and is capable of enhancing the cytotoxicity of doxorubicin (DOX) within solid tumor cells. RES is hypothesized to exert these effects by reversing the multidrug resistance (MDR) of the cancer ...
Lin Jie J Department of Cardiac and Thoracic Surgery, Affiliated Yixing People's Hospital, Jiangsu University, Yixing, Jiangsu 214200, P.R. - - 2014
The aim of the present study was to investigate whether the JWA gene regulates the proliferation, migration and invasion of human esophageal squamous cell carcinoma (ESCC) and normal human esophageal cell lines through mitogen-activated protein kinase (MAPK) signal transduction pathways. The role of JWA in proliferation, migration, invasion and apoptosis ...
Pozdnyakova Natalia - - 2014
Aim. To analyze the effects of highly selective blocker GAT1, NO-711, and substrate inhibitor GAT3, β-alanine, on the initial velocity of [(3)H]GABA uptake by cortical, hippocampal, and thalamic nerve terminals (synaptosomes) after perinatal hypoxia. Methods. Animals were divided into two groups: control (n=17) and hypoxia (n=12). Rats in the hypoxia ...
Günther A A Physics and Materials Science Research Unit, University of Luxembourg, 162A Avenue de la Faïencerie, L-1511 Luxembourg, - - 2014
The structural and magnetic properties of a cobalt nanorod array have been studied by means of magnetic field dependent small-angle neutron scattering (SANS). Measurement of the unpolarized SANS cross section dΣ/dΩ of the saturated sample in the two scattering geometries where the applied magnetic field H is either perpendicular or ...
Dugan Christine E CE Department of Nutritional Sciences, University of Connecticut, Storrs, - - 2014
Metabolic syndrome (MetS), characterized by central obesity, dyslipidemias, hypertension, and hyperglycemia, impacts 34 percent of the U.S. adult population. MetS has been demonstrated to be affected by dietary components. Data from epidemiological studies and clinical interventions suggest that one or more dairy components might directly affect MetS parameters. For example, ...
Robinson Richard R Freelance Science Writer, Sherborn, Massachusetts, United States of - - 2014
Vuković Rosemary - - 2014
Aim. To estimate the impact of high fat diet and estrogen deficiency on the oxidative and antioxidative status in the liver of the ovariectomized rats, as well as the ameliorating effect of physical activity or consumption of functional food containing bioactive compounds with antioxidative properties on oxidative damage in the ...
Liu Ming-Wei MW Department of Emergency, The First Hospital Affiliated To Kunming Medical University, Kunming, Yunnan 650032, P.R. - - 2014
Successful drug treatment for sepsis-related acute lung injury (ALI) remains a major clinical problem. Thus, the aim of the present study was to investigate the beneficial effects of salidroside on ameliorating cecal ligation and puncture (CLP)-induced lung inflammation. Rats underwent CLP surgery to induce ALI and 800 mg/kg salidroside (i.v.) ...
Huang Guobao G Department of Burn and Plastic Surgery, Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, P.R. China ; Department of Burn and Plastic Surgery, Jinan Central Hospital Affiliated to Shandong University, Jinan, Shandong 250013, P.R. - - 2014
The aim of the present study was to evaluate the clinical therapeutic effect of the combined application of alginate and recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) on the healing of refractory chronic skin ulcers. A single center, three arm, randomized study was performed at Jinan Central Hospital (Jinan, Shandong, China). ...
Ma Shengli S Department of Stomatology, Hospital of Heilongjiang Province, Harbin, Heilongjiang 150036, P.R. - - 2014
An antibacterial substance from Streptococcus sanguinis (S. sanguinis) is known to have an inhibitory effect on putative periodontal pathogens, but its inhibitory effect on pathogens of oral candidiasis is unknown. In this study, intracellular and exocrine proteins were extracted from S. sanguinis. The antagonistic effect of the protein extracts on ...
Ang Hui Ying HY Department of Cell and Molecular Biology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, - - 2014
Immunomodulators are agents that are able to stimulate or inhibit the immune response. The leaf extracts from Potentilla indica and Dendrophthoe pentandra were analyzed in vitro for immunomodulatory activity and an MTT colorimetric assay was conducted to determine the proliferation of mice splenocytes and thymocytes. A bromodeoxyuridine assay was performed ...
Ren Wei W Department of Nephrology, Anhui Provincial Hospital Affiliated to Anhui Medical University, Hefei, Anhui 230001, P.R. - - 2014
The present study aimed to investigate the pathogen distribution and drug resistance of lung infections in hemodialysis to guide clinical empirical pharmacy. The clinical data of 116 hemodialysis patients with pulmonary infection were analyzed. The majority of the 82 pathogens isolated from the sputa of patients were Gram-negative bacteria (accounting ...
Dumych Tetiana - - 2014
Aim. To develop specific fluorescent markers for melanoma tumor visualization, which would provide high selectivity and reversible binding pattern, by the use of carbohydrate-recognizing proteins, lectins, combined with the physical ability for imaging deep in the living tissues by utilizing red and near infrared fluorescent properties of specific rare-earth doped ...
Campbell Helen - - 2014
Existing pertussis surveillance systems tend to underidentify less severe cases among older children and adults. For routine follow-up of notified, nonconfirmed, clinically diagnosed pertussis cases, use of an oral fluid test was pilot tested in England and Wales during June 2007-August 2009. During that period, 1,852 cases of pertussis were ...
Salehi S S Deutsches Textilforschungszentrum Nord-West gGmbH, Universität Duisburg-Essen, - - 2014
Background: An estimated 10 million people suffer worldwide from vision loss caused by corneal damage. For the worst cases, the only available treatment is transplantation with human donor corneal tissue. However, in numerous countries there is a considerable shortage of corneal tissue of good quality, leading to various efforts to ...
Vogel A A Institut für Biomedizinische Optik, Universität zu Lübeck, Peter-Monnik-Weg 4, 23562, Lübeck, Deutschland, - - 2014
In refractive corneal surgery femtosecond (fs) lasers are used for creating LASIK flaps, dissecting lenticules and for astigmatism correction by limbal incisions. Femtosecond laser systems are complex and expensive and cutting precision is compromised by the large focal length associated with the commonly used infrared (IR) wavelengths. Based on investigations ...
Schatz-Jakobsen Janus Asbjørn JA Department of Molecular Biology and Genetics, Aarhus University, Gustav Wieds Vej 10C, DK-8000 Aarhus, - - 2014
Complement is an ancient part of the innate immune system that plays a pivotal role in protection against invading pathogens and helps to clear apoptotic and necrotic cells. Upon complement activation, a cascade of proteolytic events generates the complement effectors, including the anaphylatoxins C3a and C5a. Signalling through their cognate ...
Chitnumsub Penchit P National Center for Genetic Engineering and Biotechnology, 113 Thailand Science Park, Paholyothin Road, Klong 1, Klong Luang, Pathumthani 12120, - - 2014
Plasmodium falciparum serine hydroxymethyltransferase (PfSHMT), an enzyme in the dTMP synthesis cycle, is an antimalarial target because inhibition of its expression or function has been shown to be lethal to the parasite. As the wild-type enzyme could not be crystallized, protein engineering of residues on the surface was carried out. ...
Kim Deok-Song DS Laboratory of Veterinary Pathology, College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of - - 2014
Sapovirus, a member of the Caliciviridae family, is an important cause of acute gastroenteritis in humans and pigs. Currently, the porcine sapovirus (PSaV) Cowden strain remains the only cultivable member of the Sapovirus genus. While some caliciviruses are known to utilize carbohydrate receptors for entry and infection, a functional receptor ...
Pimentel Camila Bianco CB - - 2014
Cryosurgery is an efficient therapeutic technique used to treat benign and malignant cutaneous diseases. The primary active mechanism of cryosurgery is related to vascular effects on treated tissue. After a cryosurgical procedure, exuberant granulation tissue is formed at the injection site, probably as a result of angiogenic stimulation of the ...
Gottstein Bruno B Institute of Parasitology, Vetsuisse Faculty and Faculty of Medicine, University of Bern, Bern, - - 2014
Two recombinant Fasciola hepatica antigens, saposin-like protein-2 (recSAP2) and cathepsin L-1 (recCL1), were assessed individually and in combination in enzyme-linked immunosorbent assays (ELISA) for the specific serodiagnosis of human fasciolosis in areas of low endemicity as encountered in Central Europe. Antibody detection was conducted using ProteinA/ProteinG (PAG) conjugated to alkaline ...
Fournier Guillaume G Institut Pasteur, Unité de Génétique Moléculaire des Virus à ARN, Département de Virologie, Paris, France; CNRS, UMR 3569, Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Unité de Génétique Moléculaire des Virus à ARN, Paris, - - 2014
Influenza A viruses are major pathogens in humans and in animals, whose genome consists of eight single-stranded RNA segments of negative polarity. Viral mRNAs are synthesized by the viral RNA-dependent RNA polymerase in the nucleus of infected cells, in close association with the cellular transcriptional machinery. Two proteins essential for ...
Toledo-Ortiz Gabriela G Institute of Structural and Molecular Biology, SynthSys, University of Edinburgh, Edinburgh, United - - 2014
The ability to interpret daily and seasonal alterations in light and temperature signals is essential for plant survival. This is particularly important during seedling establishment when the phytochrome photoreceptors activate photosynthetic pigment production for photoautotrophic growth. Phytochromes accomplish this partly through the suppression of PHYTOCHROME INTERACTING FACTORS (PIFs), negative regulators ...
Chagas Andrezza C AC Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Rockville, Maryland, United States of - - 2014
Among the several challenges faced by bloodsucking arthropods, the vertebrate hemostatic response against blood loss represents an important barrier to efficient blood feeding. Here we report the first inhibitor of collagen-induced platelet aggregation derived from the salivary glands of a black fly (Simulium nigrimanum), named Simplagrin. Simplagrin was expressed in ...
Nozawa Carlos C Universidade Estadual de Londrina, Londrina, PR, - - 2014
Herpes simplex virus (HSV) infection is an endemic disease and it is estimated that 6095% of the adult population are infected with symptoms that are usually self-limiting, though they can be serious, extensive and prolonged in immunocompromised individuals, highlighted by the emergence of drug-resistant strains. The study of the wild-type ...
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