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Kahan Tara F TF Department of Chemistry, University of Toronto , Toronto, Ontario M5S 3H6 - - 2014
Conspectus Chemical interactions at the air-ice interface are of great importance to local atmospheric chemistry but also to the concentrations of pollutants deposited onto natural snow and ice. However, the study of such processes has been hampered by the lack of general, surface-specific probes. Even seemingly basic chemical properties, such ...
Makarov Valentin - - 2014
We report the synthesis and characterization of amorphous iron oxide nanoparticles from iron salts in aqueous extracts of monocotyledonous (Hordeum vulgare) and dicotyledonous (Rumex acetosa) plants. The nanoparticles were characterized by TEM, absorbance spectroscopy, SAED, EELS, XPS and DLS methods and were shown to contain mainly iron oxide and iron ...
Nelson David W DW University of Wisconsin-Madison, United - - 2014
The absorption of dietary fat involves the re-esterification of digested triacylglycerol in the enterocytes, a process catalyzed by acyl CoA:monoacylglycerol acyltransferase (MGAT) 2. Mice without a functional gene encoding MGAT2 (Mogat2(-/-)) are protected from diet-induced obesity. Surprisingly, these mice absorb normal amounts of dietary fat but increase their energy expenditure. ...
Pobegalov George - - 2014
We demonstrate an optical bistability in a laser system with incoherent optical feedback and a nanosuspension as a nonlinear element. The optical transfer function is shown to exhibit a hysteresis loop for the light power in the range of a few milliwatts. It has been found that the optical bistability ...
Wang Chuji - - 2014
We report on observation of particle cones formed by optical trapping of absorbing particles in air using two sets of simple geometric optical schemes. Further, the trapped particles on a cone in both schemes are size-sorted with large particles or particle ensembles close to the cone vertex. This new experimental ...
Zhong Biao - - 2014
In order to meet the demands for applications of optical refrigerators in the fields of spaceflight, aviation, space science, and detection, a 2 wt. % Yb<sup>3+</sup>-doped LuLiF<sub>4</sub> crystal, as a new laser cooling material, was prepared and demonstrated by using a 178 mW diode laser centered at 1015 nm and a resonant extra-cavity ...
Xu S C - - 2014
We report a long-time working femtosecond laser using metal-free sapphire-based graphene as a saturable absorber (SA). The sapphire-based graphene yielded excellent nonlinear saturable absorption properties and was demonstrated to be suitable as an SA for an ultrafast solid-state laser. Stable mode-locked pulses of 325 fs were obtained at a central wavelength ...
Xiong Huayu - - 2014
The fast, visual discrimination of β2-agonist drugs is needed for the on-site screening of various types of β2-agonists in blood and urine samples. We developed a simple, rapid, one-step colorimetric method to detect phenolic β2-agonists by use of a tyrosinase catalytic reaction, which involved the oxidation of the phenol group ...
Chaigne Thomas - - 2014
We implement the photoacoustic transmission matrix approach on a two-dimensional photoacoustic imaging system, using a 15 MHz linear ultrasound array. Using a black leaf skeleton as a complex absorbing structure, we demonstrate that the photoacoustic transmission matrix approach allows to reveal structural features that are invisible in conventional photoacoustic images, as ...
Fang S S Department of Otolaryngology, William Harvey Hospital, Ashford, - - 2014
Introduction: There is currently a lack of robust evidence on the best form of packing for otological surgery. We describe the use of the absorbable gelatin sponge, a packing material that does not require removal and has the benefit of being considerably cheaper compared to other common forms of ear ...
Lo C C Department of Anaesthesia and Pain Management, Royal Children's Hospital, Melbourne, Victoria, Australia, and Department of Paediatrics, University of Melbourne, Melbourne, Victoria, - - 2014
Children undergoing magnetic resonance imaging (MRI) often require general anaesthesia (GA). Children under GA are at risk of decreases in body temperature. This risk may be greater during MRI due to MRI scanners requiring cool ambient temperatures. Conversely, radiofrequency radiation emitted by MRI scanners is absorbed by the patient as ...
Hiraku Yusuke Y Department of Environmental and Molecular Medicine, Mie University Graduate School of Medicine, Tsu, Mie, 514-8507, Japan. Electronic address: - - 2014
Methylene blue (MB) is used for various clinical purposes, including chromoendoscopy and methemoglobinemia treatment. However, MB induces tumors of pancreatic islets and small intestine in experimental animals. This finding raises a possibility that MB induces carcinogenicity in these organs via light-independent mechanisms, although MB is known to cause light-dependent DNA ...
Rajagopal Srinath - - 2014
Enhancements to the existing primary standard optical interferometer and narrowband tone-burst comparison calibration methods for miniature medical ultrasonic hydrophones of the membrane type over the frequency range 100 to 500 kHz are described. Improvements were realized through application of an ultrasonically absorbing waveguide made of a low-frequency-absorbing tile used in ...
Schubert Amy G AG Division of Sports Medicine, University of Wisconsin Hospital and Clinics, Madison, - - 2014
A high number of recreational runners sustain a running-related injury each year. To reduce injury risk, alterations in running form have been suggested. One simple strategy for running stride frequency or length has been commonly advocated. To characterize how running mechanics change when stride frequency and length are manipulated. In ...
Wu Ho-Sheng - - 2014
Six persons in Taiwan who had contact with poultry infected with influenza A(H5N2) showed seroconversion for the virus by hemagglutinin inhibition or microneutralization testing. We developed an ELISA based on nonstructural protein 1 of the virus to differentiate natural infection from cross-reactivity after vaccination; 2 persons also showed seroconversion by ...
Ariza-Miguel Jaime - - 2014
Tularemia outbreaks occurred in northwestern Spain in 1997-1998 and 2007-2008 and affected >1,000 persons. We assessed isolates involved in these outbreaks by using pulsed-field gel electrophoresis with 2 restriction enzymes and multilocus variable number tandem repeat analysis of 16 genomic loci of Francisella tularensis, the cause of this disease. Isolates ...
Schoberle Taylor J TJ The University of Texas Graduate School of Biomedical Sciences at Houston, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of - - 2014
Secondary metabolites are produced by numerous organisms and can either be beneficial, benign, or harmful to humans. Genes involved in the synthesis and transport of these secondary metabolites are frequently found in gene clusters, which are often coordinately regulated, being almost exclusively dependent on transcription factors that are located within ...
Kumar Prabhat - - 2014
Ascochyta blight caused by Ascochyta rabiei (Pass.) Labrousse is a major biotic constraint in production of chickpea. In the present investigation, all chickpea genotypes [E100Y (m), Gaurav, Pb-7 and L550] induced 100% callus on standard medium with greenish colour and fragile structure. These calli were used for in vitro screening ...
Zhang Yumin Y Aerodynamics and Acoustics Laboratory, HKU Zhejiang Institute of Research and Innovation, Department of Mechanical Engineering, The University of Hong Kong, Hong Kong SAR, - - 2014
Broadband noise with profound low-frequency profile is prevalent and difficult to be controlled mechanically. This study demonstrates effective broadband sound absorption by reducing the mechanical reactance of a loudspeaker using a shunt circuit through electro-mechanical coupling, which induces reactance with different signs from that of loudspeaker. An RLC shunt circuit ...
Prasad A S Arun - - 2014
Bacillus halodurans MTCC 865 was employed for decolorization of textile azo dye, Acid Black-24 (AB-24). Thousand mgl⁻¹ of AB-24 was decolorized with 90% efficiency by the strain within 6 hrs at pH 9 and 37 °C with 5% NaCl under static conditions in screening medium. Decolorization was evaluated by measuring ...
Zhang Chao C School of Engineering and Technology, China University of Geosciences (Beijing), Beijing, - - 2014
Microbial contamination is a growing concern in the food safety today. To effectively control the types and degree of microbial contamination during food production, this paper introduces a design for a microbial contamination detector that can be used for quick in-situ examination. The designed detector can identify the category of ...
Cicciù Marco M From the *Oral Surgery and Oral Disease Department, School of Dentistry, University of Messina, Messina, Italy; †Department of Oral and Maxillofacial Surgery, Loma Linda University, Loma Linda, CA; ‡School of Dentistry, University of Messina, Messina, Italy; and §Department of Oral Surgery, Policlinico Cà Granda, University of Milan School of Dentistry, Milan, - - 2014
Numerous autogenous bone-grafting procedures are available for the recovering of large continuity defects of the mandible. However, these surgical techniques present several limitations involving postoperative morbidity and pain. The development of new bone technique reconstruction not involving autogenous bone graft would offer new opportunities for facial bone reconstruction.This report highlights ...
Macka Mirek M Australian Center for Research on Separation Science and School of Chemistry, University of Tasmania, Hobart, Tasmania 7001, - - 2014
Light-emitting diodes (LEDs) are playing increasingly important roles in analytical chemistry, from the final analysis stage to photoreactors for analyte conversion to actual fabrication of and incorporation in microdevices for analytical use. The extremely fast turn-on/off rates of LEDs have made possible simple approaches to fluorescence lifetime measurement. Although they ...
Vidal Natalia P - - 2014
The lipids of 16 farmed and wild European sea bass (Dicentrarchus labrax) samples were studied by Fourier transform infrared (FTIR) spectroscopy. The spectroscopic parameters which would be useful when distinguishing between both fish origins were analysed. It was shown, for the first time, that the frequency and the ratio between ...
Sgouros George G Johns Hopkins University, Baltimore, MD. Electronic address: - - 2014
Radiopharmaceutical therapy (RPT) involves the use of radionuclides that are either conjugated to tumor-targeting agents (e.g., nanoscale constructs, antibodies, peptides, and small molecules) or concentrated in tissue through natural physiological mechanisms that occur predominantly in neoplastic or otherwise targeted cells (e.g., Graves disease). The ability to collect pharmacokinetic data by ...
Lima Patrícia de Sousa Pde S Laboratório de Biologia Molecular, Instituto de Ciências Biológicas, Universidade Federal de Goiás, Goiânia, Goiás, Brazil; Programa de Pós Graduação em Patologia Molecular, Faculdade de Medicina, Universidade de Brasília, Brasília, Distrito Federal, - - 2014
The genus Paracoccidioides comprises human thermal dimorphic fungi, which cause paracoccidioidomycosis (PCM), an important mycosis in Latin America. Adaptation to environmental conditions is key to fungal survival during human host infection. The adaptability of carbon metabolism is a vital fitness attribute during pathogenesis. The fungal pathogen Paracoccidioides spp. is exposed ...
Tenreiro Sandra S Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisboa, - - 2014
Alpha-synuclein (aSyn) is the main component of proteinaceous inclusions known as Lewy bodies (LBs), the typical pathological hallmark of Parkinson's disease (PD) and other synucleinopathies. Although aSyn is phosphorylated at low levels under physiological conditions, it is estimated that ∼90% of aSyn in LBs is phosphorylated at S129 (pS129). Nevertheless, ...
Bobosha Kidist K Department of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands; Armauer Hansen Research Institute, Addis Ababa, - - 2014
Field-applicable tests detecting asymptomatic Mycobacterium leprae (M. leprae) infection or predicting progression to leprosy, are urgently required. Since the outcome of M. leprae infection is determined by cellular- and humoral immunity, we aim to develop diagnostic tests detecting pro-/anti-inflammatory and regulatory cytokines as well as antibodies against M. leprae. Previously, ...
Kedzierski Lukasz L Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria Australia; Department of Medical Biology, The University of Melbourne, Parkville, Melbourne, Victoria, - - 2014
Suppressor of cytokine signaling (SOCS) proteins are key regulators of innate and adaptive immunity. There is no described biological role for SOCS4, despite broad expression in the hematopoietic system. We demonstrate that mice lacking functional SOCS4 protein rapidly succumb to infection with a pathogenic H1N1 influenza virus (PR8) and are ...
Loc'h Jérôme J Laboratoire de Cristallographie et RMN Biologiques, UMR CNRS 8015, Université Paris Descartes, Faculté de Pharmacie, Sorbonne Paris Cité, Paris, - - 2014
During biogenesis of the 40S and 60S ribosomal subunits, the pre-40S particles are exported to the cytoplasm prior to final cleavage of the 20S pre-rRNA to mature 18S rRNA. Amongst the factors involved in this maturation step, Fap7 is unusual, as it both interacts with ribosomal protein Rps14 and harbors ...
Carneiro Zumira A ZA Faculdade de Ciências Farmacêuticas de Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, - - 2014
The parasite Trypanosoma cruzi causes Chagas disease, which remains a serious public health concern and continues to victimize thousands of people, primarily in the poorest regions of Latin America. In the search for new therapeutic drugs against T. cruzi, here we have evaluated both the in vitro and the in ...
Reimão Juliana Q JQ Departamento de Parasitologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, - - 2014
The treatment of leishmaniasis relies mostly on parenteral drugs with potentially serious adverse effects. Additionally, parasite resistance in the treatment of leishmaniasis has been demonstrated for the majority of drugs available, making the search for more effective and less toxic drugs and treatment regimens a priority for the control of ...
Rubert-Nason K F - - 2014
Plant-derived salicinoids (conjugates of glucose and salicylate phenolic moieties) are potent modulators of plant-herbivore interactions. We demonstrate the use of micro-high-performance liquid chromatography (μHPLC) with photodiode-array detection (DAD) for quantification of four salicinoids (salicin, salicortin, hydroxycyclohexen-on-oyl salicortin and tremulacin) in methanolic extracts of Populus. To develop and implement a solvent-conserving ...
Muramatsu Takashi T Thoraxcenter, Erasmus Medical Center, Rotterdam, the Netherlands; Department of Cardiology, Fujita Health University Hospital, Toyoake, - - 2014
Naffin-Olivos Jacqueline L JL Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts, United States of - - 2014
Mycobacterium tuberculosis (Mtb) employs multiple strategies to evade host immune responses and persist within macrophages. We have previously shown that the cell envelope-associated Mtb serine hydrolase, Hip1, prevents robust macrophage activation and dampens host pro-inflammatory responses, allowing Mtb to delay immune detection and accelerate disease progression. We now provide key ...
Gu Jingmin J Key Laboratory of Zoonosis, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, - - 2014
The lysin LysGH15, which is derived from the staphylococcal phage GH15, demonstrates a wide lytic spectrum and strong lytic activity against methicillin-resistant Staphylococcus aureus (MRSA). Here, we find that the lytic activity of the full-length LysGH15 and its CHAP domain is dependent on calcium ions. To elucidate the molecular mechanism, ...
Wa Maina Ciira C Department of Electrical and Electronic Engineering, Dedan Kimathi University of Technology, Nyeri, - - 2014
Gene transcription mediated by RNA polymerase II (pol-II) is a key step in gene expression. The dynamics of pol-II moving along the transcribed region influence the rate and timing of gene expression. In this work, we present a probabilistic model of transcription dynamics which is fitted to pol-II occupancy time ...
Feng Boya B Ministry of Education Key Laboratory of Protein Sciences, Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, - - 2014
Obg proteins are a family of P-loop GTPases, conserved from bacteria to human. The Obg protein in Escherichia coli (ObgE) has been implicated in many diverse cellular functions, with proposed molecular roles in two global processes, ribosome assembly and stringent response. Here, using pre-steady state fast kinetics we demonstrate that ...
Remy Estelle E Instituto Gulbenkian de Ciência, Oeiras, - - 2014
Root vacuolar sequestration is one of the best-conserved plant strategies to cope with heavy metal toxicity. Here we report that zinc (Zn) tolerance in Arabidopsis requires the action of a novel Major Facilitator Superfamily (MFS) transporter. We show that ZIF2 (Zinc-Induced Facilitator 2) localises primarily at the tonoplast of root ...
Bouafia Amine A CNRS-UMR6290 Genetic and Development Institute of Rennes, GEO Team, Rennes, France; Université de Rennes 1, UEB, SFR Biosit, Rennes, - - 2014
Genomic instability is a major hallmark of cancer. To maintain genomic integrity, cells are equipped with dedicated sensors to monitor DNA repair or to force damaged cells into death programs. The tumor suppressor p53 is central in this process. Here, we report that the ubiquitous transcription factor Upstream Stimulatory factor ...
Eftekhar Ebrahim E Deparment of Biochemistry, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran; ; Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran; ; Department of Biochemistry, School of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, - - 2014
Background: DNA methyltransferase-3B (DNMT3B) is an important enzyme responsible for maintaining the DNA methylation pattern in eukaryotic cells. In this study we have investigated the correlation between the 46359C→T polymorphism in the DNMT3B gene and the risk of breast cancer incidence among sporadic breast cancer patients in Fars Province, Southern ...
Bozek Katarzyna K CAS Key Laboratory of Computational Biology, CAS-MPG Partner Institute for Computational Biology, Shanghai, China; Max Planck Institute for Evolutionary Anthropology, Leipzig, - - 2014
Metabolite concentrations reflect the physiological states of tissues and cells. However, the role of metabolic changes in species evolution is currently unknown. Here, we present a study of metabolome evolution conducted in three brain regions and two non-neural tissues from humans, chimpanzees, macaque monkeys, and mice based on over 10,000 ...
Röltgen Katharina K Swiss Tropical and Public Health Institute, Molecular Immunology, Basel, Switzerland; University of Basel, Basel, - - 2014
A previous survey for clinical cases of Buruli ulcer (BU) in the Mapé Basin of Cameroon suggested that, compared to older age groups, very young children may be less exposed to Mycobacterium ulcerans. Here we determined serum IgG titres against the 18 kDa small heat shock protein (shsp) of M. ...
Puckett Susan S Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of - - 2014
Metabolic pathways used by Mycobacterium tuberculosis (Mtb) to establish and maintain infections are important for our understanding of pathogenesis and the development of new chemotherapies. To investigate the role of fructose-1,6-bisphosphate aldolase (FBA), we engineered an Mtb strain in which FBA levels were regulated by anhydrotetracycline. Depletion of FBA resulted ...
Paireau Juliette J Unité d'Epidémiologie des Maladies Emergentes, Institut Pasteur, Paris, France; Univ. Pierre et Marie Curie, Cellule Pasteur UPMC, Paris, - - 2014
Epidemics of meningococcal meningitis (MM) recurrently strike the African Meningitis Belt. This study aimed at investigating factors, still poorly understood, that influence annual incidence of MM serogroup A, the main etiologic agent over 2004-2010, at a fine spatial scale in Niger. To take into account data dependencies over space and ...
Papaïx Julien J INRA, UMR 1290 BIOGER, Thiverval-Grignon, France; INRA, UR 341 MIA, Jouy-en-Josas, France; CSIRO Plant Industry, Canberra, - - 2014
Metapopulation processes are important determinants of epidemiological and evolutionary dynamics in host-pathogen systems, and are therefore central to explaining observed patterns of disease or genetic diversity. In particular, the spatial scale of interactions between pathogens and their hosts is of primary importance because migration rates of one species can affect ...
Xavier Samanta Cristina das Chagas SC Laboratory of Trypanosomatid Biology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, - - 2014
The new epidemiological scenario of orally transmitted Chagas disease that has emerged in Brazil, and mainly in the Amazon region, needs to be addressed with a new and systematic focus. Belém, the capital of Pará state, reports the highest number of acute Chagas disease (ACD) cases associated with the consumption ...
Allais Gianni G Women's Headache Center, Department of Surgical Sciences, University of Turin, Via Ventimiglia 3, 10126, Turin, Italy, - - 2014
Early triptan use after headache onset may help improve the efficacy of acute migraine treatment. This may be particularly the case when triptan therapy is combined with a nonsteroidal anti-inflammatory drug (NSAID). The objective of this is to assess whether the combination of frovatriptan 2.5 mg + dexketoprofen 25 or 37.5 mg (FroDex25 and ...
de la Fuente-Núñez César C Department of Microbiology and Immunology, Centre for Microbial Diseases and Immunity Research, University of British Columbia, Vancouver, British Columbia, - - 2014
Bacteria form multicellular communities known as biofilms that cause two thirds of all infections and demonstrate a 10 to 1000 fold increase in adaptive resistance to conventional antibiotics. Currently, there are no approved drugs that specifically target bacterial biofilms. Here we identified a potent anti-biofilm peptide 1018 that worked by ...
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