Search Results
Results 11751 - 11800 of 323033

Current sort is by publication date. Click to sort by relevancy

< 231 232 233 234 235 236 237 238 239 240 241 >
Ren Tong T Department of Urinary Surgery, First Affiliated Hospital, Harbin Medical University, NanGang District, Harbin, Heilongjiang Province - - 2014
To compare the efficiency and safety of the transperitoneal approaches with retroperitoneal approaches in laparoscopic partial nephrectomy for renal cell carcinoma and provide evidence-based medicine support for clinical treatment. A systematic computer search of PUBMED, EMBASE, and the Cochrane Library was executed to identify retrospective observational and prospective randomized controlled ...
Ma Jinling J Department of Geriatric Cardiology, Chinese PLA General Hospital, Beijing, - - 2014
Glycated hemoglobin (HbA1c) is associated with an increased risk of cardiovascular disease. The aim of this study was to examine the relationship between HbA1c levels and the complexity of coronary artery lesions among the older patients with diabetes mellitus (DM). This retrospective study enrolled a total of 3805 consecutive type ...
Udegbunam Sunday Ositadinma SO Department of Veterinary Surgery, University of Nigeria, Nsukka 400001, - - 2014
Staphylococcal ocular infections of food animals have been somewhat under diagnosed probably due to the ubiquitous nature of staphylococcal organisms. This study was undertaken to determine the occurrence of staphylococcal ocular infections of food producing animals in Nsukka Southeast, Nigeria, and to determine the antibiogram of the isolated staphylococci. A ...
Koşucu Müge M Department of Anesthesiology, KTU Farabi Hospital, Medical School of Karadeniz Technical University, 61080 Trabzon, - - 2014
Purpose. To compare the effects of different anesthesia techniques on tourniquet-related ischemia-reperfusion by measuring the levels of malondialdehyde (MDA), ischemia-modified albumin (IMA) and neuromuscular side effects. Methods. Sixty ASAI-II patients undergoing arthroscopic knee surgery were randomised to three groups. In Group S, intrathecal anesthesia was administered using levobupivacaine. Anesthesia was ...
Apuri Susmitha S Internal and Hospital Medicine, Moffitt Cancer Center, University of South Florida College of Medicine, 12902 Magnolia Drive, Tampa, Florida 33612-9497, - - 2014
Tacrolimus is an immunosuppressive drug mainly used to lower the risk of transplant rejection in individuals who are post solid organ or hematopoietic transplantation. It is a macrolide which reduces peptidyl-propyl isomerase activity and inhibits calcineurin, thus inhibiting T-lymphocyte signal transduction and interleukin-2 (IL-2) transcription. It has been associated with ...
Patel Dilip Kumar DK Department of Medicine. Veer Surendra Sai Medical College, Burla, Odisha, - - 2014
Sickle cell anaemia (SCA) patients with vaso-occlusive crisis (VOC) have signs of inflammation and it is often difficult to diagnose a bacterial infection in them. This study was undertaken to evaluate the role of serum procalcitonin (PCT) as a biomarker of bacterial infection in acute sickle cell vaso-occlusive crisis. Hundred ...
Sun Li L Department of Neuropharmacology, Institute of Nautical Medicine, Nantong University, Jiangsu, - - 2014
The present study was conducted to clarify whether treatment with L-serine can improve the brain repair and neurorestoration of rats after permanent middle cerebral artery occlusion (pMCAO). After pMCAO, the neurological functions, brain lesion volume, and cortical injury were determined. GDNF, NGF, NCAM L1, tenascin-C, and Nogo-A levels were measured. ...
Boye Shannon E SE Department of Ophthalmology, College of Medicine, University of Florida, Gainesville, Florida, United States of - - 2014
Mutations in the CEP290 (cilia-centrosomal protein 290 kDa) gene in Leber congenital amaurosis (LCA) cause early onset visual loss but retained cone photoreceptors in the fovea, which is the potential therapeutic target. A cone-only mouse model carrying a Cep290 gene mutation, rd16;Nrl-/-, was engineered to mimic the human disease. In ...
Wu Dong-Feng DF Department of Cardiology, Institute of Cardiovascular Diseases, the First Affiliated Hospital, Guangxi Medical University, 22 Shuangyong Road, Nanning 530021, Guangxi, China. - - 2014
The present study was performed to clarify the association between the acyl-CoA:cholesterol acyltransferase-1 (ACAT-1) single nucleotide polymorphism (SNP) rs1044925 and the risk of coronary artery disease (CAD) and ischemic stroke (IS) in the Guangxi Han population. Polymerase chain reaction and restriction fragment length polymorphism was performed to determine the genotypes ...
Wichaiwong Tanakorn T 0000-0002-6936-3120 Department of Computer Science, Faculty of Science, Kasetsart University, Bangkok 10903, - - 2014
XML document is now widely used for modelling and storing structured documents. The structure is very rich and carries important information about contents and their relationships, for example, e-Commerce. XML data-centric collections require query terms allowing users to specify constraints on the document structure; mapping structure queries and assigning the ...
Gao Lu L Department of Neurosurgery, First Affiliated Hospital, Wenzhou Medical University, Wenzhou 325000, Zhejiang, China. - - 2014
The immune system, particularly T lymphocytes and cytokines, has been implicated in the progression of brain injury after intracerebral hemorrhage (ICH). Although studies have shown that transplanted neural stem cells (NSCs) protect the central nervous system (CNS) from inflammatory damage, their effects on subpopulations of T lymphocytes and their corresponding ...
Turner Karly M KM Queensland Brain Institute, The University of Queensland, St Lucia, - - 2014
Genetic (G) and environmental (E) manipulations are known to alter behavioural outcomes in rodents, however many animal models of neuropsychiatric disorders only use a restricted selection of strain and housing conditions. The aim of this study was to examine GxE interactions comparing two outbred rat strains, which were housed in ...
Denton Anne - - 2014
Corticosteroids are a potent group of medicines, with many adverse effects, that are widely prescribed in palliative care for both specific and non-specific indications. The aim of this study was to document current patterns of corticosteroid prescribing in New Zealand palliative care settings and to reflect on whether they were ...
Aydin Umit U Institute for Biomagnetism and Biosignalanalysis, Westfälische Wilhelms-Universität Münster, Münster, - - 2014
To increase the reliability for the non-invasive determination of the irritative zone in presurgical epilepsy diagnosis, we introduce here a new experimental and methodological source analysis pipeline that combines the complementary information in EEG and MEG, and apply it to data from a patient, suffering from refractory focal epilepsy. Skull ...
Li Bingjin B Second hospital of Jilin University, Changchun, China; National Engineering Laboratory for Druggable Gene and Protein Screening Northeast Normal University, Changchun, - - 2014
Recently, studies have shown that serotonin plays an important role in the control of seizure. However, the specific role of 5-HT receptor subtypes is not yet well described, in particular that of the 5-HT3 receptor. The present study was aimed to investigate the role of 5-HT3 receptor on the pentylenetetrazole ...
Walther Feli M FM MSD Animal Health Innovation GmbH, Zur Propstei, 55270 Schwabenheim, Germany. - - 2014
Fluralaner is a novel systemic ectoparasiticide for dogs providing long-acting flea- and tick-control after a single oral dose. This study investigated the safety of oral administration of fluralaner at 3 times the highest expected clinical dose to Multi Drug Resistance Protein 1 (MDR1(-/-)) gene defect Collies. Sixteen Collies homozygous for ...
Kim H J HJ Stanford University, 450 BroadwayStreet Pavilion C, 4th floor, RedwoodCity, California, 94063-6342, - - 2014
Resveratrol is a polyphenolic compound commonly found in the skins of red grapes. Sirtuin 1 (SIRT1) is a human gene that is activated by resveratrol and has been shown to promote longevity and boost mitochondrial metabolism. We examined the effect of resveratrol on normal and osteoarthritic (OA) human chondrocytes. Normal and ...
Duchenne Jonathan J Emergency Department, Henri Mondor Hospital, Aurillac, - - 2014
To determine whether copeptin-us can rule out diagnosis of non-ST-segment elevation myocardial infarction (NSTEMI) without prolonged monitoring and serial blood sampling in patients with high-sensitive cardiac troponin I (hs-cTnT) below the 99th centile at presentation to the emergency department (ED). Prospective, non-randomised, individual blinded diagnostic accuracy study. Two EDs of ...
Nuccio Sean-Paul SP Department of Medical Microbiology and Immunology, School of Medicine, University of California at Davis, Davis, California, - - 2014
ABSTRACT The Salmonella genus comprises a group of pathogens associated with illnesses ranging from gastroenteritis to typhoid fever. We performed an in silico analysis of comparatively reannotated Salmonella genomes to identify genomic signatures indicative of disease potential. By removing numerous annotation inconsistencies and inaccuracies, the process of reannotation identified a ...
Mesa Franklin F University of Central Florida, Orlando, Florida, United States of - - 2014
Although social anxiety disorder (SAD) is most often diagnosed during adolescence, few investigations have examined the clinical presentation and daily functional impairment of this disorder exclusively in adolescents. Prior studies have demonstrated that some clinical features of SAD in adolescents are unique relative to younger children with the condition. Furthermore, ...
Kuběna Aleš Antonín AA Department of Philosophy and History of Science, Faculty of Science, Charles University, Prague, Czech - - 2014
Allowing players to punish their opponents in Public Goods Game sustains cooperation within a group and thus brings advantage to the cooperative individuals. However, the possibility of punishment of the co-players can result in antisocial punishment, the punishment of those players who contribute the most in the group. To better ...
Antal Márk M University of Szeged, Faculty of Dentistry, Department of Operative and Esthetic Dentistry, Szeged, - - 2014
Population-based studies have identified smoking as a pathogenetic factor in chronic periodontitis. At the same time, chronic periodontal disease has also been found to occur more often in persons suffering from psoriasis than in controls with no psoriasis. It is known that smoking aggravates both periodontal disease and psoriasis, but ...
Zhang Dongfeng D Department of Cardiology, Capital Medical University affiliated Beijing Anzhen Hospital, Beijing Institute of Heart, Lung and Blood Vessel Disease, Beijing, - - 2014
The best strategy for ST-segment elevation myocardial infarction (STEMI) patients with multivessel disease (MVD), who underwent primary percutaneous coronary intervention (PCI) in the acute phase, is not well established. Our goal was to conduct a meta-analysis comparing culprit vessel only percutaneous coronary intervention (culprit PCI) with multivessel percutaneous coronary intervention ...
Yilmazel Ucar Elif E Department of Pulmonary Diseases, Ataturk University, School of Medicine, Erzurum, - - 2014
Background The study aimed to compare the efficacy and safety of nebulized steroid (NS) with systemic corticosteroids (SC) and to determine optimal NS dose in the treatment of patients with COPD exacerbations requiring hospitalization. Material and Methods The study was a randomized, parallel design trial. Eligible patients (n=86) were randomly ...
Aldababseh Mahmoud M Department of Electronic Engineering, Al-Quds University, P.O. Box 20002, Jerusalem, - - 2014
We address the problem of estimating time-varying fading channels in filter bank multicarrier (FBMC/OQAM) wireless systems based on pilot symbols. The standard solution to this problem is the least square (LS) estimator or the minimum mean square error (MMSE) estimator with possible adaptive implementation using recursive least square (RLS) algorithm ...
Parsons N N University of Warwick, Statisticsand Epidemiology, Warwick Medical School, Coventry, CV47AL, - - 2014
To study the measurement properties of a joint specific patient reported outcome measure, a measure of capability and a general health-related quality of life (HRQOL) tool in a large cohort of patients with a hip fracture. Responsiveness and associations between the Oxford Hip Score (a hip specific measure: OHS), ICEpop ...
Willis Andrew A Diabetes Research Unit, University of Leicester, Leicester, United - - 2014
Risk factors for cardiovascular disease including diabetes have seen a large rise in prevalence in recent years. This has prompted interest in prevention through the identifying individuals at risk of both diabetes and cardiovascular disease and has seen increased investment in screening interventions taking place in primary care. Community pharmacies ...
Sun Wei W Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China; Shanghai Key Laboratory of Orthopaedic Implants, Shanghai, PR China; Department of Orthopaedic Surgery, the Affiliated Hospital of Xuzhou Medical College, Xuzhou, PR - - 2014
The effect of Sox9 on the differentiation of bone marrow mesenchymal stem cells (BMSCs) to nucleus pulposus (NP)-like (chondrocyte-like) cells in vitro has been demonstrated. The objective of this study is to investigate the efficacy and feasibility of Sox9-transduced BMSCs to repair the degenerated intervertebral disc in a rabbit model. ...
Zhang Duo D Department of Orthopaedics, Second Affiliated Hospital of Medical College of Xi'an Jiaotong University, Xi'an, Shaanxi Province, People's Republic of - - 2014
To compare the efficacy of the therapy of spinal cord injury with intravenous transplantation of bone marrow mesenchymal stem cells (BMSCs) by Meta-analysis. Studies of the BBB scores after intravenous transplantation of BMSCs were searched out from Pubmed, SCI, Cochrane Library, Chinese journal full-text database, China Biology Medicinedisc and Wanfang ...
Graziotin Daniel D Faculty of Computer Science, Free University of Bozen-Bolzano , Bolzano , - - 2014
For more than thirty years, it has been claimed that a way to improve software developers' productivity and software quality is to focus on people and to provide incentives to make developers satisfied and happy. This claim has rarely been verified in software engineering research, which faces an additional challenge ...
Ashkenazi Malka M Pediatric Dentist, Private practice, Petach-Tikva , - - 2014
Objective. To evaluate the success rate of intra-rectal (IR) midazolam in combination with nitrous oxide/oxygen (N2O) sedation in young uncooperative dental patients when the local anesthesia is delivered by a computerized controlled local anesthetic delivery (C-CLAD). Study Design. This observational study consisted of 219 uncooperative children (age: 4.3 ± 1.69 ...
Moreno-Santos Inmaculada I Unidad de Gestión Clínica de Endocrinología y Nutrición, Hospital Universitario Virgen de la Victoria, Instituto de Investigación Biomédica de Málaga (IBIMA), Málaga, Spain; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERobn, CB06/03), Instituto de Salud Carlos III, Santiago de Compostela, - - 2014
To further understand the pharmacological properties of N-oleoylethanolamine (OEA), a naturally occurring lipid that activates peroxisome proliferator-activated receptor alpha (PPARα), we designed sulfamoyl analogs based on its structure. Among the compounds tested, N-octadecyl-N'-propylsulfamide (CC7) was selected for functional comparison with OEA. The performed studies include the following computational and biological ...
Siriussawakul Arunotai A Department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, - - 2014
The use of supplemental oxygen in uncomplicated cesarean deliveries under spinal anesthesia has been thoroughly investigated during recent decades. The aim of this study was to determine the benefits for both mother and infant of administering supplemental, low-dose oxygen via a nasal cannula versus having no supplement (i.e., room air ...
Blanco-Rojo Ruth R Department of Metabolism and Nutrition, Institute of Food Science, Technology and Nutrition (ICTAN), Spanish National Research Council (CSIC), C/José Antonio Novais 10, Madrid 28040, Spain. - - 2014
The aim of this study was to investigate the combined influence of diet, menstruation and genetic factors on iron status in Spanish menstruating women (n = 142). Dietary intake was assessed by a 72-h detailed dietary report and menstrual blood loss by a questionnaire, to determine a Menstrual Blood Loss ...
Kim Min Young MY The University of Queensland, UQ Centre for Clinical Research, Brisbane, - - 2014
Inadequate maintenance of systemic blood flow in neonates following preterm birth is associated with increased morbidity and mortality, and may be due in part to structural immaturity of the myocardium. Maternal glucocorticoid administration is associated with improved cardiovascular function, and possibly promotes structural maturation of the myocardium. This study assessed ...
Chowdhury Rajiv R Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge CB1 8RN, - - 2014
To evaluate the extent to which circulating biomarker and supplements of vitamin D are associated with mortality from cardiovascular, cancer, or other conditions, under various circumstances. Systematic review and meta-analysis of observational studies and randomised controlled trials. Medline, Embase, Cochrane Library, and reference lists of relevant studies to August 2013; ...
Sung Valerie V Royal Children's Hospital, Parkville, Victoria, - - 2014
To determine whether the probiotic Lactobacillus reuteri DSM 17938 reduces crying or fussing in a broad community based sample of breastfed infants and formula fed infants with colic aged less than 3 months. Double blind, placebo controlled randomised trial. Community based sample (primary and secondary level care centres) in Melbourne, ...
Ristau Tina T Department of Ophthalmology, University Hospital of Cologne, Cologne, - - 2014
Age-related macular degeneration (AMD) is a common condition that leads to severe vision loss and dysregulation of the complement system is thought to be associated with the disease. To investigate associations of polymorphisms in AMD susceptibility genes with systemic complement activation, 2655 individuals were genotyped for 32 single nucleotide polymorphisms ...
Ling Guiying G Department of Biology, Guizhou Normal University, Guiyang, Guizhou, - - 2014
Cathelicidins, a class of gene-encoded effector molecules of vertebrate innate immunity, provide a first line of defense against microbial invasions. Although cathelicidins from mammals, birds, reptiles and fishes have been extensively studied, little is known about cathelicidins from amphibians. Here we report the identification and characterization of two cathelicidins (cathelicidin-RC1 ...
Thompson Richard L RL Department of Molecular Genetics, Microbiology, and Biochemistry, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of - - 2014
Both viral and host genetics affect the outcome of herpes simplex virus type 1 (HSV-1) infection in humans and experimental models. Little is known about specific host gene variants and molecular networks that influence herpetic disease progression, severity, and episodic reactivation. To identify such host gene variants we have initiated ...
Miguelez Cristina C Department of Pharmacology, Faculty of Medicine and Dentistry, University of the Basque Country UPV/EHU Leioa, Spain ; Department of Pharmacology, Faculty of Pharmacy, University of the Basque Country UPV/EHU Vitoria-Gasteiz, - - 2014
The neurotransmitter serotonin (5-HT) has a multifaceted function in the modulation of information processing through the activation of multiple receptor families, including G-protein-coupled receptor subtypes (5-HT1, 5-HT2, 5-HT4-7) and ligand-gated ion channels (5-HT3). The largest population of serotonergic neurons is located in the midbrain, specifically in the raphe nuclei. Although ...
Raghunath Sushravya S Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, Minnesota, United States of - - 2014
Diffuse parenchymal lung diseases (DPLDs) are characterized by widespread pathological changes within the pulmonary tissue that impair the elasticity and gas exchange properties of the lungs. Clinical-radiological diagnosis of these diseases remains challenging and their clinical course is characterized by variable disease progression. These challenges have hindered the introduction of ...
Ganasegeran Kurubaran K 0000-0002-9480-1815 International Medical School, Management and Science University (MSU), Shah Alam 40100 Selangor, - - 2014
Background. Symptomatic knee osteoarthritis, an ancient malady greatly impairing modern population quality of life, has stimulated global attention to find effective modes of prevention and intervention. Purpose. This study aimed to assess factors affecting knowledge of symptomatic knee osteoarthritis (knee OA) among Malaysian railway workers. Methods. A cross-sectional study was ...
Walton Courtney C CC Healthy Brain Ageing Program, Brain and Mind Research Institute, University of Sydney Sydney, NSW, - - 2014
Justa Shivali S Section of Rheumatology, Department of Medicine, and the Arizona Arthritis Center, University of Arizona, Tucson, Arizona, United States of - - 2014
IL-22 is elevated in patients with inflammatory arthritis and correlates with disease activity. IL-22 deficient mice have reduced incidence of arthritis. Recombinant IL-22 restrains progression of arthritis via increase in IL-10 responses when administered prior to onset of arthritis. These findings imply a possible dual role of IL-22 in inflammatory ...
Mei Leilei L Center for Studies of Psychological Application and School of Psychology, South China Normal University, Guangzhou, China; Department of Psychology and Social Behavior, University of California Irvine, Irvine, California, United States of - - 2014
Although behavioral and neuropsychological studies have suggested two distinct routes of phonological access, their neural substrates have not been clearly elucidated. Here, we designed an artificial language (based on Korean Hangul) that can be read either through addressed (i.e., whole word mapping) or assembled (i.e., grapheme-to-phoneme mapping) phonology. Two matched ...
Huang Yan Y Department of Anesthesiology, School of Medicine, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200011, China. - - 2014
Recent studies have shown that dexmedetomidine exerts an anti-inflammatory effect by reducing serum levels of inflammatory factors, however, the up-stream mechanism is still unknown. The transcription factor NF-κB enters the nucleus and promotes the transcription of its target genes, including those encoding the pro-inflammatory cytokines IL-6 and TNF-α. In this ...
Jung Carla S CS Department of Neurosurgery, University of Heidelberg, Heidelberg D-69120, Germany. - - 2014
Previous results on nitric oxide (NO) metabolism after traumatic brain injury (TBI) show variations in NO availability and controversial effects of exogenous nitric oxide synthase (NOS)-inhibitors. Furthermore, elevated levels of the endogenous NOS inhibitor asymmetric dimethylarginine (ADMA) were reported in cerebro-spinal fluid (CSF) after traumatic subarachnoid hemorrhage (SAH). Therefore, we ...
Galvao Tais F TF Faculty of Medicine, University of Brasilia, P.O. Box 4472, 70904-970 Brasilia, DF, Brazil ; Getulio Vargas University Hospital, Federal University of Amazonas, 69020-170 Manaus, AM, - - 2014
Objective. To assess the effects of problem-based learning (PBL) on the learning achievements of pharmacy students. Methods. We searched for controlled studies that compared PBL to traditional learning in pharmacy courses (graduate and undergraduate) in the major literature databases up to January 2014. Two independent researchers selected the studies, extracted ...
Bellón Juan Á JÁ Centro de Salud El Palo, Departamento de Medicina Preventiva, Universidad de Málaga, Málaga, Spain; Instituto de Investigación Biomédica de Málaga, Unidad de Investigación del Distrito Sanitario Málaga, Málaga, - - 2014
The predictD study developed and validated a risk algorithm for predicting the onset of major depression in primary care. We aimed to explore the opinion of patients about knowing their risk for depression and the values and criteria upon which these opinions are based. A maximum variation sample of patients ...
< 231 232 233 234 235 236 237 238 239 240 241 >
Recent Searches