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RESTELL M - - 1965
Relevancy Score: Relevancy Score: 396
BIRDWOOD B - - 1965
Relevancy Score: Relevancy Score: 396
BEEUWKES H - - 1957
Relevancy Score: Relevancy Score: 396
Frank R M - - 1973
Relevancy Score: Relevancy Score: 396
Wahlberg J E - - 1971
Relevancy Score: Relevancy Score: 396
Emilson C G - - 1973
Relevancy Score: Relevancy Score: 396
Hennessey T S - - 1973
Relevancy Score: Relevancy Score: 396
Engelmann U - - 1981
Relevancy Score: Relevancy Score: 396
De Siena F - - 2012
OBJECTIVE: The aim of this study was to compare the use of two chlorhexidine-based antimicrobial agents as an adjunct to mechanical therapy for the treatment of peri-implant mucositis. MATERIALS AND METHODS: Thirty patients with peri-implant mucositis were included in the study and randomized in two groups. In addition to mechanical ...
Relevancy Score: Relevancy Score: 395
Bhat Nagesh - - 2014
Abstract Background: The aim of this study was to compare the efficacy, safety, antiplaque and antigingivitis properties of a herbal mouthwash with chlorhexidine mouthwash. Methods: A double-blinded randomized clinical trial was conducted among 72 undergraduate students with age group 18-24 years. They were randomly divided into three mouthwash group with ...
Relevancy Score: Relevancy Score: 395
Shafiei Fereshteh F Department of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, - - 2013
Considering the possibility of remaining bacteria in the cavity or invading via microgaps, the use of antibacterial agents in adhesive restoration may be beneficial. This study evaluated the effect of chlorhexidine on immediate and long-term shear bond strength of adhesives with and without antibacterial agent to dentin. In this in ...
Relevancy Score: Relevancy Score: 395
Plaut B S - - 1980
The commercially available salts of chlorhexidine were found to interact with the hydrogel poly (2-hydroxyethyl methacrylate) to different extents, the affinity for the polymer decreasing in the order acetate, gluconate, chloride. The uptakes of the acetate and gluconate salts were almost entirely irreversible over the concentration range studied. The influence ...
Relevancy Score: Relevancy Score: 395
Musial Witold - - 2009
The aim of this work was the evaluation of conductivity assessments for the monitoring and controlling the release study process of chlorhexidine and lidocaine hydrochloride from the ionic polyacrylic gel, applying different temperatures. According to performed measurements of release, the chlorhexidine, characterized by very low water solubility, is observed in ...
Relevancy Score: Relevancy Score: 395
Sanderson P J - - 1985
Seven babies born to 28 mothers who were vaginal carriers of group B streptococci and who bathed or showered with chlorhexidine during the last 2 weeks of pregnancy were colonized with an organism of the same phage type as their mothers. In contrast, nine babies of 14 carrier mothers who ...
Relevancy Score: Relevancy Score: 395
Rahman M R - - 1998
The management of suppurative keratitis due to filamentous fungi presents severe problems in tropical countries. The aim was to demonstrate the efficacy of chlorhexidine 0.2% drops as an inexpensive antimicrobial agent, which could be widely distributed for fungal keratitis. Successive patients presenting to the Chittagong Eye Institute and Training Complex ...
Relevancy Score: Relevancy Score: 395
Yusof Z A - - 1988
Chlorhexidine, an antiseptic with a wide antimicrobial spectrum, was first introduced as a general disinfectant in medical use. In dentistry, it was first used for disinfecting surgical sites and in endodontics. Its anti-plaque effect was later discovered and this lead to its widespread use as a plaque control agent available ...
Relevancy Score: Relevancy Score: 394
Juliano Claudia - - 2008
The aim of this work was to investigate the suitability of some polymeric films as buccal systems for the delivery of the antiseptic drug chlorhexidine diacetate, considered as a valid adjunct in the treatment of oral candidiasis. Six different film formulations, mono- or double-layered, containing 5 or 10 mg of ...
Relevancy Score: Relevancy Score: 394
Shipskiń≠ A V - - 2007
Sensitivity of microflora representatives isolated from inflammatory foci from 40 patients with suppurative-inflammatory diseases of maxillo-facial region and neck to different concentrations of antiseptic preparations of polyhexametylenguanide hydrochloride (Biopag) and chlorhexidine bigluconate was tested. It was determined that 0.05-0.1% solutions of these antiseptics were optimal for these diseases treatment. Biopag ...
Relevancy Score: Relevancy Score: 394
Twetman S - - 1997
The aim of the present study was to evaluate and compare the efficacy of a chlorhexidine/thymol-containing (CHX) and a chlorhexidine/thymol/fluoride-containing (CHX + F) varnish to decrease interdental levels of mutans streptococci (MS). Eighty-two healthy schoolchildren (11-13 years) with high scores of salivary MS were selected by a screening procedure and ...
Relevancy Score: Relevancy Score: 394
Ohta S - - 1990
The mechanisms of resistance of Serratia marcescens and Pseudomonas cepacia to chlorhexidine were studied. Leakage of the cellular component such as protein was observed in a chlorhexidine sensitive strain (S1) of S. marcescens when S1 was treated with chlorhexidine at 40 micrograms/ml concentration, while this phenomenon was not observed in ...
Relevancy Score: Relevancy Score: 393
Herrera David - - 2013
Data sourcesMedline, Embase and Cochrane Central Register of Controlled Trials (CENTRAL) databases were searched along with the reference lists of all selected studies. Only English language studies were included.Study selectionRandomised controlled clinical trials comparing chlorhexidine (CHX) to placebo/control mouthrinses for oral hygiene in studies of at least four weeks duration ...
Relevancy Score: Relevancy Score: 393
Piovano Susana - - 2005
The aim of the present work was to evaluate the effect of a thymol/chlorhexidine varnish at 1% on Streptococcus mutans (S. mutans) in saliva applied after teaching and evaluating an oral hygiene technique and dressing the cavities to reduce the bacterial load. Streptococcus mutans levels in saliva samples and dental ...
Relevancy Score: Relevancy Score: 393
Lin Shaul - - 2006
OBJECTIVE: The aim of this study was to evaluate and compare the antibacterial effect of chlorhexidine and calcium hydroxide slow-release devices on oral bacteria. METHOD AND MATERIALS: The agar diffusion test was used to evaluate the antibacterial effect of the slow-release devices Activ Point (chlorhexidine; Roeko) and Calcium Hydroxide Plus ...
Relevancy Score: Relevancy Score: 393
Johnson Aaron J - - 2010
The purpose of this study was to evaluate effectiveness of an advance, at-home chlorhexidine-impregnated skin preparation cloth in decreasing the incidence of deep periprosthetic hip arthroplasty infections. Arthroplasty surgeons at the senior author's institution provided their patients with chlorhexidine-impregnated single-use cloths for use at home the night before and the ...
Relevancy Score: Relevancy Score: 393
Roberts Nesta - - 2011
Ventilator-associated pneumonia (VAP) is a common complication of mechanical ventilation after endotracheal intubation. The role of chlorhexidine and tooth-brushing has been considered as a clinical intervention to reduce infection rates, however, evidence to inform this needs appraising. This paper presents a critical review on the effect of chlorhexidine gluconate (CHX) ...
Relevancy Score: Relevancy Score: 393
Owens J - - 1997
The removal of plaque by toothbrushing with toothpaste is the most common form of plaque control in the developed world. However, the use of chemical adjuncts such as mouthrinses is increasing. In practice mouthrinses and toothpaste are used together, however, in many clinical trials, employed to assess mouthrinse activity, toothpaste ...
Relevancy Score: Relevancy Score: 393
Fisher R G - - 1975
The comparative ability of chlorhexidine diacetate and structurally related compounds to generate surface pressure at air-water and n-hexane-water interfaces, and to adsorb to hydroxyapatite, was determined. The order of effectiveness generally evident was 1-(p-chlorophenyl)-5-n-octylbiguanide acetate is greater than chlorhexidine diacetate 1-(p-chlorophenyl)-5-n-hexylbiguanide acetate is greater than 1-(p-chlorophenyl)-5-n-propylbiguanide acetate is greater than ...
Relevancy Score: Relevancy Score: 392
Fischman S - - 1975
The end point methodology did not indicate a difference between the agents. The prophylaxis effect was only demonstrable through 8 weeks, although the analysis of variance indicated a prophylaxis effect on gingival index throughout the study. An agent effect was not demonstrable in the study. The "positive control," chlorhexidine, did ...
Relevancy Score: Relevancy Score: 392
Vahdaty A - - 1993
Solutions of 0.2% and 2% chlorhexidine, 0.2% and 2% sodium hypochlorite (NaOCl) and normal saline were tested for their efficacy in disinfecting dentinal tubules following root canal irrigation in vitro. Freshly extracted bovine incisor roots were prepared as cylindrical shapes, 4 mm high and 5 mm wide with a lumen ...
Relevancy Score: Relevancy Score: 392
Goldenberg Robert L - - 2012
Infection-related neonatal mortality due to omphalitis in developing country home births is an important public health problem. Three cluster randomized trials of 4% chlorhexidine applied to the umbilical cord stump from once to multiple times in the days following a home birth have evaluated this intervention compared with other types ...
Relevancy Score: Relevancy Score: 392
Hirata Kiyotaka - - 2002
As ingestion of chlorhexidine gluconate (CHG) usually causes relatively mild symptoms, this chemical has been considered safe. An 80-y-old woman with dementia accidentally ingested approximately 200 ml of Maskin (5% CHG) in a nursing home and then presumably aspirated gastric contents. She was intubated for airway protection in the nearest ...
Relevancy Score: Relevancy Score: 392
Oydna J - - 1982
Secretory IgA is usually found in high concentrations in the mucin layer of the oral mucosa. Chlorhexidine (CH) has been shown to precipitate mucin and may thus reduce the amount of IgA available in the oral cavity. Two human experiments were performed using single radial immunodiffusion (SRID) for quantitation of ...
Relevancy Score: Relevancy Score: 392
Schwebel Carole - - 2011
BACKGROUND:: The randomized two-way factorial Dressing Study (1,636 patients, 28,931 catheter days) showed that a chlorhexidine-impregnated sponge decreased the incidence of major catheter-related infections from 1.4‰ to 0.6‰ catheter days, and that scheduled dressing changes every 7 days was not inferior to scheduled changes every 3 days. Here, we assessed ...
Relevancy Score: Relevancy Score: 392
Bizhang Mozhgan - - 2007
PURPOSE: To evaluate the effect of varnish with different chlorhexidine concentrations on the demineralization of dentin surfaces in situ. METHODS: An intraoral model was used to study the ability of chlorhexidine to prevent demineralization. Dentin specimens from extracted human teeth were treated with chlorhexidine varnish and exposed to the oral ...
Relevancy Score: Relevancy Score: 391
Attin R - - 2003
The objective of the present prospective trial was to compare the efficacy of differently concentrated chlorhexidine varnishes (EC40) = 40% chlorhexidine and Cervitec = 1% chlorhexidine + 0.1% thymol) on levels of Mutans streptococci (ms), lactobacilli (lb) and plaque formation in interproximal plaque and saliva. Twenty-four volunteers with a high ...
Relevancy Score: Relevancy Score: 391
Stabholz A - - 1993
Substantivity of tetracycline HCl and chlorhexidine digluconate to human root dentin was assessed in vitro. 51 extracted single-rooted teeth, their crowns removed, were assigned to 1 of 4 treatments in groups of 12. A control groups included 3 roots. Each group was divided into 3 subgroups to allow evaluation of ...
Relevancy Score: Relevancy Score: 391
Amitha H - - 1995
The effect of 0.2% chlorhexidine mouth wash (Hexidine) on the plaque microflora was evaluated on children wearing intra oral removable appliances. Plaque samples were collected from the enamel sections, both primary and permanent, mounted on the removable appliances. These appliances were worn by 12 children for one week. Plaque was ...
Relevancy Score: Relevancy Score: 391
Wilson M - - 1996
Biofilms of Streptococcus sanguis and planktonic cells of the organism were exposed to chlorhexidine gluconate and cetylpyridinium chloride, at concentrations used clinically, and survivors enumerated. S. sanguis exhibited a lower susceptibility to both antiseptics when it comprised a biofilm than when the organism was in the planktonic form. No viable ...
Relevancy Score: Relevancy Score: 391
Stiefel D J - - 1995
A sample of 44 adults with severe disabilities completed a randomized single-blind cross-over study testing chlorhexidine swabbing under various conditions: with/without prior dental prophylaxis, reduced frequency of application (2 vs. 5 times per week), and prolonged use (42 weeks). All subjects received therapeutic doses of 10 mL 0.12% chlorhexidine gluconate ...
Relevancy Score: Relevancy Score: 391
Leyes Borrajo J L - - 2002
Plaque control is the main method for preventing periodontal diseases. Chlorhexidine digluconate mouthrinse is widely recognized as helping to maintain plaque control. Most of these mouthrinses contain alcohol, making them impractical for many patients, including those with oral mucosal hypersensitivity. Mouthrinses without alcohol might cause fewer side effects, but also ...
Relevancy Score: Relevancy Score: 391
Mengistu Y - - 1999
To investigate the susceptibility of clinical isolates of gram-negative bacteria to chlorhexidine gluconate. Prospective laboratory study. Tikur Anbessa Hospital, Addis Ababa, Ethiopia. Clinical specimens from 443 hospital patients. Significant number of gram negative bacteria were not inhibited by chlorhexidine gluconate (0.02-0.05%) used for antisepsis. Four hundred and forty three strains ...
Relevancy Score: Relevancy Score: 391
Sanz M - - 1994
In this 6 months randomized, stratified double-blind parallel study, plaque, gingivitis, calculus formation and tooth staining were assessed in 208 participants. The participants either used a 0.12% chlorhexidine rinse and a gum care dentifrice (positive control) or a placebo rinse and the gum care dentifrice (control) or the placebo rinse ...
Relevancy Score: Relevancy Score: 391
Weitz M - - 1992
The inhibitory effect of a chlorhexidine rinse on gingival inflammation and plaque accumulation has been well documented. The purpose of this study was to determine whether a twice daily oral rinse with 0.12% chlorhexidine will resolve denture-associated inflammation in a geriatric population. Thirty-six subjects, average age 83 years, were randomly ...
Relevancy Score: Relevancy Score: 391
Jayathillake Anuradha - - 2006
To investigate the effect of chlorhexidine gluconate in urethral local anesthetic gel on patients undergoing outpatient flexible cystoscopy. We postulated that chlorhexidine was contributing to the pain and urgency that occurs during and after cystoscopy. A prospective randomized single-blinded study was conducted. A total of 141 patients undergoing outpatient flexible ...
Relevancy Score: Relevancy Score: 391
Ersin Nazan Kocatas - - 2006
The aim of this study was to examine the changes in the cultivable microflora of carious dentin before and after atraumatic restorative treatment (ART) and investigate the inhibitory effect of chlorhexidine-gluconate-based cavity disinfectant in the microflora. Using a split mouth design, 35 primary molar pairs with class II carious lesions ...
Relevancy Score: Relevancy Score: 391
Noiri Yuichiro - - 2003
Porphyromonas gingivalis is found in subgingival biofilm and is associated with periodontal disease. Bacteria in biofilms are able to resist higher antimicrobial concentrations than in suspension. Little is known about the susceptibility of P. gingivalis in biofilms to antimicrobial agents. The effects of chlorhexidine gluconate, minocycline hydrochloride, and metronidazole on ...
Relevancy Score: Relevancy Score: 391
Mimoz Olivier - - 2007
Although chlorhexidine-based solutions and alcohol-based povidone-iodine have been shown to be more efficient than aqueous povidone-iodine for skin disinfection at catheter insertion sites, their abilities to reduce catheter-related infection have never been compared. Consecutively scheduled central venous catheters inserted into jugular or subclavian veins were randomly assigned to be disinfected ...
Relevancy Score: Relevancy Score: 391
Jhamb Swaty - - 2010
To evaluate and compare the antibacterial effects of chlorhexidine and calcium hydroxide on Enterococcus faecalis. Root canal treatment involves a number of steps. In spite of all the steps done thoroughly, root canal treatment might fail due to the remnant microbes. Of all such bacteria, E. faecalis is found in ...
Relevancy Score: Relevancy Score: 391
Murray Michael R - - 2011
Deep infection after shoulder surgery is a rare but devastating problem. This study tested the hypothesis that the home application of a 2% chlorhexidine gluconate cloth before shoulder surgery would be more efficacious than a standard shower of soap and water at decreasing the preoperative cutaneous levels of pathogenic bacteria ...
Relevancy Score: Relevancy Score: 391
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