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< 1870 1871 1872 1873 1874 1875 1876 1877 1878 1879 1880 >
Maru G B - - 1980
Effect of isoniazid on blood ammonia levels and protein biosynthesis in tissues of Swiss mice was studied. Isoniazid treatment resulted in an elevation of the blood ammonia. It inhibited the protein biosynthesis in lung and kidney tissues of Swiss mice after 24 h of treatment. Simultaneous administration of L-arginine or ...
Relevancy Score: Relevancy Score: 141
Vasilevskaia N E - - 1978
The unit activity in the vagal lobe of medulla oblongata in response to stimulation of the mouth cavity and gills chemoreceptors with solutions of hydrochloric acid and sodium chloride was studied in immobilized carps and compared with those in the facial lobe in response to skin chemoreceptors stimulation. The firing ...
Relevancy Score: Relevancy Score: 141
Kohno Emiko - - 2008
Prostaglandin E(1) (PGE(1); Alprostadil Alfadex) is a potent vasodilator and inhibitor of platelet aggregation used to treat patients with peripheral vascular disease. The main adverse effects of intravenous PGE(1) administration, phlebitis and venous pain, arise from the unphysiologically low pH of infusion solutions. When PGE(1) infusion solutions with a pH ...
Relevancy Score: Relevancy Score: 141
Weinstock M - - 2004
Three models are described in rats which attempt to mimic morphological and behavioural pathology of Alzheimer's dementia; intracerebroventricular injection of streptozotocin (STZ), permanent bilateral carotid artery occlusion (2VO) and brain mitochondrial cytochrome oxidase inhibition by sodium azide. Learning and memory are impaired within 4 weeks in all models. This probably ...
Relevancy Score: Relevancy Score: 141
Costantin L L - - 1968
1. The effect of extracellular calcium and magnesium on the contraction threshold and on the thresholds for an increase in sodium and potassium conductance with depolarization was studied in voltage-clamped frog muscle fibres.2. A larger depolarization was required to reach each of the three thresholds when the concentration of divalent ...
Relevancy Score: Relevancy Score: 141
Watson W E - - 1986
Previous studies have reported that rats drink more saline after area postrema has been removed. The results presented here indicate that prolonged administration of angiotensin II into area postrema of unrestrained rats at 4 pmol/h also caused them to drink more saline. They drank more when angiotensin was released in ...
Relevancy Score: Relevancy Score: 141
Thibonnier M - - 1983
Plasma aldosterone levels were measured as part of two suppression tests in 31 hypertensive patients on normal sodium diet and without recent treatment. Thirteen patients had essential hypertension, 6 had probable bilateral adrenal hyperplasia and 12 had confirmed Conn's adenoma. In the first test, aldosterone levels were measured in the ...
Relevancy Score: Relevancy Score: 141
Noireaud J - - 1989
The effects of the glycoside saponin on ferret ventricular muscle have been investigated. Saponin produced a positive inotropic effect, the extent of which was determined by the bathing calcium concentration. If the bathing calcium concentration is reduced to levels equivalent to those found intracellularly then similar saponin concentrations are able ...
Relevancy Score: Relevancy Score: 141
Fukuda N - - 1997
Dibutyryl cyclic AMP (DBcAMP) directly stimulates the release of renin from the juxtaglomerular (JG) cells in vitro. We investigated the effect of DBcAMP on plasma renin activity (PRA) in 6 normal men and in 8 patients with primary aldosteronism (PA). A 20-min infusion of 0.33 mg/kg/min of DBcAMP significantly increased ...
Relevancy Score: Relevancy Score: 141
Chow L C - - 2002
A previous study showed that a sodium hexafluorosilicate-calcium chloride-based two-solution fluoride (F) rinse containing 6 mmol/l of F was more effective than a 12 mmol/l F sodium fluoride rinse in depositing F on tooth surfaces and increasing oral F levels. The present study compared the remineralization effects of these two ...
Relevancy Score: Relevancy Score: 141
Ormerod A D - - 1999
A double-blind, group-sequential clinical trial of acidified nitrite was performed to demonstrate the efficacy of this nitric oxide donor in treating molluscum contagiosum. Subjects received either 5% sodium nitrite co-applied with 5% salicylic acid under occlusion, or identical cream with 5% salicylic acid, omitting sodium nitrite. Active and control treatment ...
Relevancy Score: Relevancy Score: 141
Newton P - - 2001
OBJECTIVES: The objective was to determine whether or not dietary salt intake affects the relative bioavailability of oral quinine. Salt intake has been shown to alter quinidine bioavailability. METHODS: The pharmacokinetic properties of oral quinine sulphate (600 mg salt) were investigated in seven healthy Caucasian volunteers, in a randomised, crossover ...
Relevancy Score: Relevancy Score: 141
Goulding A - - 1988
High sodium chloride intakes are regarded as a risk factor for osteoporosis because they increase the obligatory urinary calcium loss and stimulate parathyroid activity. Sodium chloride loads induce osteopenia in the rat. The effect could be due to a decrease in bone formation or a rise in bone resorption. Two ...
Relevancy Score: Relevancy Score: 141
Reed C E - - 1988
During the ragweed season of 1984 we studied 120 patients with hay fever; 58 had a history of asthma during the ragweed season the year before. They were divided into four treatment groups to receive nasal sprays of placebo, cromolyn sodium, flunisolide, or beclomethasone. In controlling hay fever symptoms all ...
Relevancy Score: Relevancy Score: 141
Thews O - - 1992
A decision support system has been developed that determines the optimal dialysate bicarbonate concentration in hemodialysis therapy for each patient individually. The knowledge about the behavior of the acid-base state during treatment has been provided by a mathematical model for the description of dynamic exchange processes during hemodialysis. This model ...
Relevancy Score: Relevancy Score: 141
Patak R V - - 1975
Furosemide and the prostaglandin synthetase inhibitor, indomethacin, were administered singly and in combination to four normal subjects and six patients with essential hypertension in order to determine whether the antihypertensive, natriuretic and other effects of furosemide could be altered by inhibition of prostaglandin synthesis. In all subjects indomethacin treatment alone ...
Relevancy Score: Relevancy Score: 141
Dichter M A - - 1983
Rat cortical neurons in 4- to 7-week-old dissociated cell cultures have action potentials (APs) which are tetrodotoxin-sensitive and appear to be generated by conventional sodium mechanisms. Approximately 10% of neurons can also generate APs when sodium channels are blocked. These latter APs are smaller, slower and sensitive to cobalt. When ...
Relevancy Score: Relevancy Score: 141
Beauwens R - - 1986
Several polycations added to the luminal solution were found to inhibit the vasopressin (ADH)-induced water flow in toad urinary bladder but not the ADH-induced increase in sodium transport or in urea permeability. Ultrastructural studies were conducted to evaluate the uptake of cationized ferritin. It was found that endocytosis of cationized ...
Relevancy Score: Relevancy Score: 141
Sen B H - - 1998
OBJECTIVE: The aim of this study was to investigate the effect of titanium tetrafluoride solution on L929 fibroblasts by scanning electron microscopy. Titanium tetrafluoride was then compared with sodium fluoride and acidulated phosphate fluoride. STUDY DESIGN: Cells were treated with fluoride solutions for 1 minute either directly, through a filter ...
Relevancy Score: Relevancy Score: 141
Jakubovicz D E - - 1987
Two consequences of cerebral ischemia are cell acidification and cytotoxic edema. To test the possibility that Na+/H+ exchange mediates acid-induced edema, we measured cytoplasmic pH (pHi) and cell volume changes in C6 glioma cells that were artificially acid-loaded using weak electrolytes. pHi was monitored fluorimetrically with 2',7'-bis-(2-carboxyethyl)-5,6-carboxyfluorescein. Upon acidification with ...
Relevancy Score: Relevancy Score: 141
Garrett M - - 1984
Larvae of Culiseta inornata (Williston) can survive and complete development in dilutions of sea water ranging from 50-700 mosmol kg-1. The larvae hyperregulate with regard to haemolymph osmotic concentration in dilute media (50-400 mosmol kg-1) and osmoconform when external salinities exceed 400 mosmol kg-1. This pattern of osmoregulation is distinct ...
Relevancy Score: Relevancy Score: 141
Skok V I - - 1978
Ionic mechanisms of EPSP and depolarization evoked by iontophoretically applied acetylcholine (Ach) and serotonin (5-hydroxytryptamine, 5-HT) in the neurons of the rabbit isolated superior cervical ganglion (ACh-potential and 5-HT-potential, respectively) were studied using intracellular electrodes. Reversal potentials of EPSP (EEPSP) and Ach-potential (EACh) were -14.4 +/- 1.6 mV and -16.5 ...
Relevancy Score: Relevancy Score: 141
Danner I - - 1995
Phenotypical expression of cystic fibrosis (CF) includes decreased epithelial chloride secretion and increased sodium absorption. These anomalies produce increased water absorption and a dehydrated mucus responsible for decreased mucociliary clearance. Identification of the gene responsible for the genetic disease (CFTR for cystic fibrosis transmembrane conductance regulator) together with a more ...
Relevancy Score: Relevancy Score: 141
Yanai M - - 1998
Continuous monitoring of serum solute concentrations throughout a dialysis session could be beneficial for the prevention of intradialytic morbidity such as hypotension and for the confirmation of dialysis adequacy. In this paper, we introduce a new on-line monitoring system for use during hemodialysis sessions, a system developed for the continuous ...
Relevancy Score: Relevancy Score: 141
Ikonomidou-Turski C - - 1988
The muscarinic cholinergic agonist pilocarpine induces in rats seizures and status epilepticus followed by widespread damage to the forebrain. The present study was designed to investigate the effect of 5 non-steroidal anti-inflammatory drugs, sodium salicylate, phenylbutazone, indomethacin, ibuprofen and mefenamic acid, on seizures produced by pilocarpine. Pretreatment of rats with ...
Relevancy Score: Relevancy Score: 141
Zhao Yong - - 2004
Voltage-gated sodium channels are members of a large family with similar pore structures. The mechanism of opening and closing is unknown, but structural studies suggest gating via bending of the inner pore helix at a glycine hinge. Here we provide functional evidence for this gating model for the bacterial sodium ...
Relevancy Score: Relevancy Score: 141
Niarchos A P - - 1982
The hemodynamic and plasma catecholamine responses to isometric exercise and head up tilt were investigated in normotensive and hypertensive subjects during normal and low sodium intake and before and during the administration of the converting enzyme inhibitors teprotide or captopril. Although teprotide and captopril decreased significantly the mean arterial pressure ...
Relevancy Score: Relevancy Score: 141
Kravtsova V V - - 1978
The K+-acetylphosphatase and K+-p-nitrophenylphosphatase activities in the fraction of brain microsomes were studied as affected by anionic (sodium desoxycholate and sodium dodecyl sulphate) and nonionic (triton X-100 and digitonin) surface-active substances. The most activating concentrations of these substances are determined and their similarity with those for Na+, K+-ATPase is marked. ...
Relevancy Score: Relevancy Score: 141
Möhring J - - 1976
Rats with unilateral nephrectomy were offered 1% sodium chloride as drinking fluid and were injected with desoxycorticosterone trimethylacetate (D.O.C.-T.M.A.) at weekly intervals. During the fourth to seventh week after the start of the experiment, malignant hypertension developed in most of the animals: body weight fell, reflecting volume depletion; serum osmolality ...
Relevancy Score: Relevancy Score: 141
Scope Alon - - 2003
In recent years, New World cutaneous leishmaniasis has been seen at a higher incidence among returning Israeli travelers. Leishmania braziliensis and related species cause unsightly cutaneous lesions possibly complicated with a mucosal disease. A total of 12 patients with New World cutaneous leishmaniasis were treated in our clinic, 11 of ...
Relevancy Score: Relevancy Score: 141
Aryeetey Richmond N O - - 2008
Subclinical mastitis (SCM) is an asymptomatic inflammation of mammary tissue and has been associated with lactation failure, suboptimal growth in early infancy, and increased risk of mother-to-child transmission of HIV via breast milk. A rapid survey was carried out to determine the prevalence of SCM among lactating Ghanaian women between ...
Relevancy Score: Relevancy Score: 141
Wang Q - - 1998
OBJECTIVE: To study the effect of chitosan in the prevention of fibrous scar formation in the epidural space after laminectomy. METHOD: Fourty-eight SD rats were used as the animal model. Laminectomy was performed in lumber 1, and the exposed dura was covered with hyaluronate (group A), free fat (group B), ...
Relevancy Score: Relevancy Score: 141
Bryant D H - - 1975
In a previous study it was reported that a group of asthmatic patients, in whom cromolyn sodium did not inhibit bronchial immediate allergic reactions, had reaginic antibodies that did not appear to belong to the IgE class. This study was designed to extend these observations, and it was shown that ...
Relevancy Score: Relevancy Score: 141
Haynes R B - - 1997
Does dietary sodium in excess of a specified daily consumption substantively elevate blood pressure in normotensive people? Does lowering the daily consumption of sodium reduce blood pressure in normotensive people? Sound observational and interventional studies can address these questions, but there are substantial differences in the ability of various research ...
Relevancy Score: Relevancy Score: 141
Gerzer R - - 2005
The present manuscript summarizes recent discoveries that were made by studying salt and fluid homeostasis in weightlessness. These data indicate that 1. atrial natriuretic peptide appears not to play an important role in natriuresis in physiology, 2. the distribution of body fluids appears to be tightly coupled with hunger and ...
Relevancy Score: Relevancy Score: 141
Tarakanov I A - - 1992
In experiments on sodium pentobarbital (40 mg/kg, i. p.) anesthetized mongrel cats of either sex weighting from 2.0 to 4.0 kg, it was stated, that sodium or lithium hydroxybutyrate (HOB) (200 mg/kg, i. v.) effectively slowed down breathing with inspiratory holdings. Thus 3-5 minutes after HOB administration, eupneic pattern of ...
Relevancy Score: Relevancy Score: 141
Burger B M - - 1976
The influence of barbiturate anesthesia on renal blood flow was assessed by the xenon washout method in trained dogs with catheters chronically implanted in the renal artery. Anesthesia induced with either thiopental sodium or pentobarbital sodium resulted in a striking reduction in renal blood flow (4.1 +/- 0.1 vs. 2.6 ...
Relevancy Score: Relevancy Score: 141
Dvorák P - - 2008
Meat of wild boar with an intial (137)Cs activity concentration of 103 Bq kg(-1) of fresh mass was treated by brining. Dry-salting reduced the (137)Cs activity only by about 12-18%. Subsequent brining was done by using both pure sodium chloride and a mixture of sodium chloride and potassium nitrate. After ...
Relevancy Score: Relevancy Score: 141
Cope Darcy J - - 2009
There is a gap in the literature concerning the chemical effects that household products may produce on human remains. The present study examines the effects of household chemical products on teeth. A total of eight chemicals were utilized for this experiment. The corrosive chemical categories include: hydrochloric acid, sulfuric acid, ...
Relevancy Score: Relevancy Score: 141
Levy S B - - 1977
Changes in hemodynamic variables and plasma renin activity (PRA) induced by short-term alteration of blood pressure and sympathetic nervous system activity were studied in normotensive and hypertensive men on high-sodium and low-sodium intake. Blood pressure and heart rate alterations caused by standard cold pressor tests, amyl nitrite inhalation, phentolamine infusion, ...
Relevancy Score: Relevancy Score: 141
Obizoba I C - - 1993
The study was aimed at investigating the nutrient and tannin composition of fermented legume seeds (oil bean, castor oil bean and African locust bean) used as food condiments in Nigeria. The legume seeds were purchased from local retailers, cleaned and subjected to varied fermentation periods. Standard assay techniques were adopted ...
Relevancy Score: Relevancy Score: 141
Colt E W - - 1982
The body composition of three unipolar and 17 bipolar patients, studied during the depressive state, was compared with that of 48 controls. The ratio of extracellular to intracellular water content was significantly less in male patients than in male controls: the difference between female patients and female controls was not ...
Relevancy Score: Relevancy Score: 141
Belokurov Iu N - - 1981
The state of the kinin system in mechanical jaundice and possible ways for its normalization were analysed on the basis of clinico-experimental observations. In 32 patients with postoperative hepatic insufficiency developed against the background of mechanical jaundice a considerable activation of the kinin system was detected which was found to ...
Relevancy Score: Relevancy Score: 141
Lee N - - 1977
The infrared spectrum of a structural lipoprotein from the Escherichia coli outer membrane indicated the lipoprotein had an alpha-helical conformation but no sign for the existence of beta-structures. From circular dichroism spectra of the lipoprotein, the alpha-helical content of the protein was found to be as high as 88% in ...
Relevancy Score: Relevancy Score: 141
Dunaev V V - - 1976
On a model of transplantable albeolar-mucous RS cancer it is shown that hydrocortisone, desoxycorticosteonre-acetate (DOCA), cyanocobalamine used in combination with folic and nicotinic acids does not lower the cytostatic activity of thiophosphamide and in a number cases even potentiates its action. A relation between changes occurring under the influence of ...
Relevancy Score: Relevancy Score: 141
Goncharevskaia O A - - 1985
The effect of cobalt on renal tubular electrolyte and water handling was studied in the newt using the method of stationary microperfusion of the proximal and early distal tubules. Na, K, Ca, Mg and Cl concentrations were measured by electron probe analysis in tubule samples. 3H inulin was used to ...
Relevancy Score: Relevancy Score: 141
Robinson J W - - 1975
Segments of dog colon were subjected to one hour's ischaemia, and their morphology and function were studied either immediately after the ischaemia or 24 hours later. As functional tests, net sodium transport across the mucosa in vitro, the transport capacity in vitro for sugars and amino-acids, tissue respiration, lactate production, ...
Relevancy Score: Relevancy Score: 141
Mizumoto H - - 1993
Effects of an adenosine A1-receptor agonist and antagonist were determined in pertussis toxin (IAP)-treated and non-treated rats. (-)-N6-(2-phenylisopropyl) adenosine, an adenosine A1-agonist, reduced the urine volume and sodium excretion without decreasing the glomerular filtration rate at 0.1 mg/kg (p.o.) in both IAP-treated and non-treated rats. Diuretic effects of KW-3902 (8-(noradamantan-3-yl)-1,3-dipropylxanthine) ...
Relevancy Score: Relevancy Score: 141
Hogan J S - - 1989
Eight strains of Staphylococcus aureus were tested to determine if prolonged exposure to commercial teat dips could enhance bacterial tolerance to teat dips in vitro. All strains of S. aureus were serially plated 15 times on chemically defined agar medium containing sublethal concentrations of linear dodecyl benzene sulfonic acid, chlorhexidine, ...
Relevancy Score: Relevancy Score: 141
Semenov V Iu - - 1985
This paper presents the results of examinations of 19 test subjects exposed to head-down tilting at -8 and -15 degrees and of 14 test subjects kept in water immersion for 24 hours. During the first hours of exposure the renal excretion of water and monovalent ions increased. Renin and aldosterone ...
Relevancy Score: Relevancy Score: 141
< 1870 1871 1872 1873 1874 1875 1876 1877 1878 1879 1880 >