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< 1870 1871 1872 1873 1874 1875 1876 1877 1878 1879 1880 >
Golikov P P - - 1994
On the basis of Scatchard and Lineweaver-Burk analysis, it was demonstrated that a series of drugs either activated or inhibited the function of types II and III glucocorticoid receptors. Analgine (0.04-10.0 mM) and sodium salicylate (12.5-50.0 mM) suppress the type II glucocorticoid receptor function of rat liver cytosol. Maradol (5.0 ...
Relevancy Score: Relevancy Score: 141
Noé S - - 1998
Separation buffers for the determination of the corticosteroids cortisone, hydrocortisone, prednisone and prednisolone with micellar electrokinetic chromatography were developed with respect to separation efficacy and the migration times, depending on the type and the concentration of the organic modifier acetonitrile as well as on the addition of gamma-cyclodextrin. The buffer ...
Relevancy Score: Relevancy Score: 141
Chan S T - - 1982
Early weight gain by starving patients managed with total parenteral nutrition has been regarded as spurious - that is, merely an increase in body water. We designed an experiment to mimic the starved state in which glycogen stores are depleted and sodium intake is very low. The subjects were then ...
Relevancy Score: Relevancy Score: 141
Hannula Minna - - 2008
The CmeABC efflux pump plays an important role in the antimicrobial resistance of Campylobacter jejuni and Campylobacter coli. The aim of this investigation was to study the effect of putative efflux pump inhibitors, phenyl-arginine-beta-naphthylamide (PAbetaN) and 1-(1-naphthylmethyl)-piperazine (NMP), as well as the effect of putative efflux pump inducers, sodium salicylate ...
Relevancy Score: Relevancy Score: 141
Amichot M - - 1993
In Drosophila, the para gene has been shown to encode a functional voltage-dependent sodium channel. We used a cDNA clone to study the distribution of its transcripts by in situ mRNA hybridization on adult fly sections. These transcripts are found in cortical regions of the central nervous system and in ...
Relevancy Score: Relevancy Score: 141
Keusch G - - 1980
Plasma catecholamines and renal function were evaluated in 18 patients with essential hypertension treated with the alpha and beta adrenoceptor blocking agent, labetalol. Following 6 weeks of labetalol therapy, blood levels of epinephrine and norepinephrine remained unaltered. Glomerular filtration rate and renal plasma flow were decreased similarly by about 20% ...
Relevancy Score: Relevancy Score: 141
Asztemborska Monika - - 2003
Micellar electrokinetic chromatography (MEKC) was applied for enantioseparation of selected flavanones, including naringin, hesperidin, neohesperidin, naringenin, hesperetin, pinostrobin, isosakuranetin, eriodictyol, and homoeriodictyol. gamma-Cyclodextrin (gamma-CD) and sodium cholate (SCh) were used as chiral modifiers inducing enantioselectivity to the background electrolyte. From among many investigated selectors only these two appeared to possess ...
Relevancy Score: Relevancy Score: 141
Clauss W - - 1985
Water and electrolyte transport (Na, K, Cl) and the electrical potential difference were investigated simultaneously in five segments of rabbit colon in vivo, under control conditions and under the influence of aldosterone. A dialysis method was used. The solution was designed to mimic the electrolyte concentration of the lumen, and ...
Relevancy Score: Relevancy Score: 141
Tepperman B L - - 1978
The actions of 16,16-dimethyl prostaglandin E2 (dmPGE2) were investigated on ion transport in in vitro rabbit fundic mucosa and rat isolated jejunal cells. Addition of dmPGE2 (1.3 X 10(-4)M) to the serosal side of the rabbit mucosa resulted in a significant decrease in the transmural potential difference (PD) and short ...
Relevancy Score: Relevancy Score: 141
Kurachi M - - 1985
Using the sucrose gap method, the effect of taurine on the response to glutamate in the ventral root of the isolated frog spinal cord was investigated. The depolarization induced by glutamate was reduced by taurine and the inhibitory action of taurine was antagonized by strychnine, but not by picrotoxin or ...
Relevancy Score: Relevancy Score: 141
Zimmerman Deena R - - 2009
In this preliminary prospective study, breast milk is sampled surrounding 4 religious fast days to determine the effect of a more than 24-hour fast on breast milk composition. The participants are 48 healthy women nursing healthy babies between 1 and 6 months of age. Samples are collected within 2 days ...
Relevancy Score: Relevancy Score: 141
Nlewem Kingsley C - - 2010
Three different pretreatment methods for switchgrass were studied. Aqueous sodium hydroxide (0.5-10% w/v, 90 degrees C, 1h), dilute H(2)SO(4) (0.5-6.0% v/v, 121 degrees C, 1h) and hot water (100 degrees C, 1h) were employed in this study to determine how each method affected the digestibility of switchgrass during enzymatic hydrolysis. ...
Relevancy Score: Relevancy Score: 141
Zambraski E J - - 1976
Low-level direct renal nerve stimulation increases both renal tubular sodium reabsorption and renal renin secretion rate without changing arterial pressure, glomerular filtration rate, renal blood flow, or intrarenal blood flow distribution. The possibility was considered that intrarenal angiotensin II formation might mediate the antinatriuretic effect by directly enhancing renal tubular ...
Relevancy Score: Relevancy Score: 141
Chung Youn Wook - - 2006
The possible effects of sodium selenite on mature osteoclasts were investigated. Incubation of osteoclast-like cells differentiated from RAW 264.7 cells with sodium selenite induced apoptosis as revealed by morphological changes, internucleosomal DNA fragmentation, and activation of caspase-3. Selenite also induced generation of the superoxide anion and reduced the number of ...
Relevancy Score: Relevancy Score: 141
Shreffler W - - 1997
Genetic data suggest that unc-8 is a member of the epithelial sodium channel (ENaC) gene family (shreffler et al., 1995). Consistent with this idea, cosmid R13A1, containing an ENaC homolog, can restore normal locomotion to unc-8 mutants after germline transformation. To identify other genes encoding proteins that regulate ENaC function, ...
Relevancy Score: Relevancy Score: 141
Strichartz G R - - 1981
Recent experiments are reviewed to present a current view of the mechanisms of conduction block by local anesthetics. Local anesthetics block the sodium channels whose opening causes the rising phase of the action potential. Both charged and neutral forms of local anesthetics are able to block channels. Charged anesthetics interfere ...
Relevancy Score: Relevancy Score: 141
Crouzy S C - - 1993
Conti and Stühmer (1989. Eur. Biophys. J. 17:53-59) have measured the nonstationary shot noise in the gating current of a population of sodium channels. Here we present expressions for the autocovariance and variance of such noise from general Markov models of channel kinetics, based on the theoretical work of E. ...
Relevancy Score: Relevancy Score: 141
Pedemont C H - - 2001
In different species and tissues, a great variety of hormones modulate Na+,K+-ATPase activity in a short-term fashion. Such regulation involves the activation of distinct intracellular signaling networks that are often hormone- and tissue-specific. This minireview focuses on our own experimental observations obtained by studying the regulation of the rodent proximal ...
Relevancy Score: Relevancy Score: 141
Hadad Ghada M - - 2008
Multivariate spectrophotometric calibration and liquid chromatographic (LC) methods were applied to the determination of 2 multicomponent mixtures containing diprophylline, guaiphenesin, methylparaben, and propylparaben (Mixture 1), or clobutinol, orciprenaline, saccharin sodium, and sodium benzoate (Mixture 2). For the multivariate spectrophotometric calibration methods, principal component regression (PCR) and partial least-squares regression (PLS-1), ...
Relevancy Score: Relevancy Score: 141
Chervinskaia A V - - 2002
AIM: Assessment of the efficacy of dry high-dispersive aerosol of sodium chloride--the main acting factor of haloaerosol therapy--on defense system of the respiratory tract. MATERIAL AND METHODS: 188 patients with respiratory disease and at risk of pulmonary pathology received course of haloaerosol therapy. 49 matched patients were given placebo. The ...
Relevancy Score: Relevancy Score: 141
Kanner B I - - 2001
Glutamate transporters are essential for terminating synaptic excitation and for maintaining extracellular glutamate concentrations below neurotoxic levels. These transporters also mediate a thermodynamically uncoupled chloride flux that is activated by two of the molecules that they transport - sodium and glutamate. Five eukaryotic glutamate transporters have been cloned and identified. ...
Relevancy Score: Relevancy Score: 141
Komoda Toshikazu - - 2007
The biosynthesis of tetrapetalones (tetrapetalones A, B, C, and D) in Streptomyces sp. USF-4727 was studied by feeding experiments with [1-13C] sodium propanoate, [1-13C] sodium butanoate, [carbonyl-13C] 3-amino-5-hydroxybenzoic acid (AHBA) hydrochloride, and [1-13C] glucose, followed by analysis of the 13C-NMR spectra. These feeding experiments revealed that the four tetrapetalones were ...
Relevancy Score: Relevancy Score: 141
Bräunlich H - - 1989
In conscious rats, administration of vanadate is followed by a distinct and statistically significant diuretic effect. The increase in renal excretion of sodium dominates in comparison with other electrolytes. After i.p. administration vanadate is effective for 30 to 60 min. In anesthetized rats an excessive saline load and i.v. administration ...
Relevancy Score: Relevancy Score: 141
Wack R P - - 1997
The electrolyte composition of breast milk beyond 6 months postpartum has not been extensively examined, particularly chloride concentrations. A total of 140 samples of breast milk from 30 breast-feeding mothers were collected and analyzed. Mean mother's values +/- standard error of sodium (141 +/- 17 mg/L), potassium (480 +/- 11 ...
Relevancy Score: Relevancy Score: 141
Wauters J P - - 1979
Eight patients on chronic haemodialysis for six months to 7 years with hypertension resistant to ultrafiltration and antihypertensive therapy, received Captopril (SQ 14, 225) an orally active inhibitor of converting enzyme. With this therapy, blood pressure was controlled in the 4 patients with the highest plasma renin activity. In the ...
Relevancy Score: Relevancy Score: 141
Cummins Theodore R - - 2009
We provide here detailed electrophysiological protocols to study voltage-gated sodium channels and to investigate how wild-type and mutant channels influence firing properties of transfected mammalian dorsal root ganglion (DRG) neurons. Whole-cell voltage-clamp recordings permit us to analyze kinetic and voltage-dependence properties of ion channels and to determine the effect and ...
Relevancy Score: Relevancy Score: 141
Vér A - - 1989
Plasma membrane derived from the myometrial tissues of pregnant and non-pregnant rats accumulates Ca2+ both by Na+ and by ATP-dependent ways. Sodium-dependent Ca2+-uptake in plasma membranes obtained from 20 days pregnant rats reveals higher Ca2+ sensitivity than in plasma membrane of non-pregnant rats. Ca2+ concentration required for half maximal Ca2+-transport ...
Relevancy Score: Relevancy Score: 141
Fukui Shinji - - 2004
We retrospectively studied 133 patients with subarachnoid hemorrhage (SAH) to assess whether there was any gender disparity in serum electrolytes levels throughout the clinical course. Serum concentrations of sodium and potassium were measured in all patients, while catecholamines or antidiuretic hormone were assessed in a number of cases. Female SAH-patients ...
Relevancy Score: Relevancy Score: 141
Laragh J H - - 1988
Essential hypertension is a heterogeneous spectrum of pathophysiologic disturbances, not a single entity. Identification and characterization of two different vasoconstrictor mechanisms--one renin-mediated, the other sodium-volume mediated--has made it possible not only to apply antihypertensive drug therapy on a more rational basis but to screen out a significant number of cases ...
Relevancy Score: Relevancy Score: 141
Kostakoglu N - - 1989
Induced physiologic changes in the gastric mucosa was investigated both in the presence of normal gastric acidity and after parietal cell vagotomy (PCV), in dogs. Cholecystogastrostomy and common bile duct ligation was performed in eleven and PCV was added to this procedure in five dogs. During histopathological examination, 70 days ...
Relevancy Score: Relevancy Score: 141
Salmon B - - 1990
Using sodium cromoglycate as a non-toxic marker, we assessed the delivery of aerosol to nine wheezy infants and seven healthy adults. The drug was delivered to the infants by face mask and spacer device from a metered dose inhaler, and by face mask and nebuliser to the infants and the ...
Relevancy Score: Relevancy Score: 141
Wilson H J - - 2007
While preeclampsia is common in pregnancy, associated hyponatraemia is rare with very few cases reported in the literature. We report the case of a previously healthy nulliparous woman who presented at 34 weeks' gestation with hypertension and proteinuria. On admission her serum sodium was 122mmol/L and by day 6, in ...
Relevancy Score: Relevancy Score: 141
Ogata N - - 1988
Effects of deltamethrin, a pyrethroid insecticide, and lindane, the gamma isomer of hexachlorocyclohexane, on the gamma-aminobutyric acid (GABA)-activated ion channels were studied using cultured neurons isolated from the newborn rat dorsal root ganglia. The neuron was voltage clamped using the whole cell patch clamp technique. Two components of inward chloride ...
Relevancy Score: Relevancy Score: 141
Rodrigues C M - - 1996
The quantitative extraction of bile acids and their conjugates from serum was investigated using different commercially available reversed-phase bonded silica cartridges. Serum was diluted with 0.1 M sodium hydroxide or 0.5 M triethylamine sulphate, pH 7.0, and heated at 64 degrees C for 20-30 min prior to application to the ...
Relevancy Score: Relevancy Score: 141
Chen K - - 1999
Spontaneous activity was recorded in the dorsal cochlear nucleus of brain slices from mice homozygous for the med-J and jolting mutations in the neuronal sodium channel alpha-subunit Scn8a. Densities of spontaneously active neurons in slices from both mutants were significantly lower than in control slices. Spontaneous firing patterns with bursts ...
Relevancy Score: Relevancy Score: 141
López R - - 2003
The available evidence supporting the importance of cyclooxygenase-2 (COX-2) in the regulation of renal haemodynamics and excretory function is summarized. Cyclooxygenase-2-derived metabolites play a very important role in regulating renal haemodynamics when sodium intake is low whereas it plays a minor role in the control of cortical blood flow when ...
Relevancy Score: Relevancy Score: 141
Ferguson J W - - 2002
An in vitro study was conducted to determine the susceptibility of the yeast Candida albicans to various intracanal irrigants and medications. The minimum inhibitory concentration (MIC) of sodium hypochlorite, hydrogen peroxide, chlorhexidine digluconate, and aqueous calcium hydroxide that is required to kill a standardized inoculum of C. albicans was determined. ...
Relevancy Score: Relevancy Score: 141
Nelson Filho P - - 2000
The objective was to determine the level of contamination of toothbrushes by mutans streptococci using microbiological identification, to access the bacterial contamination using scanning electron microscopy (SEM) and to evaluate the efficacy of two toothbrush disinfectants. Nineteen children used their toothbrushes once a day, for five consecutive days. The toothbrushes ...
Relevancy Score: Relevancy Score: 141
Bi Jian - - 2010
As the desire to promote health increases, reductions of certain ingredients, for example, sodium, sugar, and fat in food products, are widely requested. However, the reduction is not risk free in sensory and marketing aspects. Over reduction may change the taste and influence the flavor of a product and lead ...
Relevancy Score: Relevancy Score: 141
Macdonald R L - - 1993
Clinically used antiepileptic drugs (AEDs) decrease membrane excitability by interacting with ion channels or neurotransmitter receptors. Currently available AEDs appear to act on sodium channels, GABAA receptors, or calcium channels. Phenytoin, carbamazepine, and possibly valproate (VPA) decrease high-frequency repetitive firing of action potentials by enhancing sodium channel inactivation. Benzodiazepines and ...
Relevancy Score: Relevancy Score: 141
Hirshman C A - - 1983
To understand the mechanisms underlying the bronchoconstrictor response to 10% citric acid administered for 5 min in Basenji-Greyhound (BG) dogs, we evaluated the protection afforded by atropine (0.2 and 0.4 mg/kg iv) and by aerosols of isoproterenol (1 mg/ml) and cromolyn sodium (20 mg/ml). In untreated dogs, citric acid increased ...
Relevancy Score: Relevancy Score: 141
Steiger V - - 1987
L-Glutamic acid uptake by bovine pulmonary arterial endothelial cells in culture increased linearly with time up to 30 min and did not show saturation with increased substrate concentration up to 6 X 10(-3) M. The uptake per cell decreased as cell density increased and was lowest when the cells became ...
Relevancy Score: Relevancy Score: 141
Teisseire B P - - 1979
We have assessed the characteristics of oxygen transport following chronic intraperitoneal administration of sodium cyanate (NaCNO, 90 mg/kg; P50 decreased), o-iodosodium benzoate (OISB, 300 mg/kg; P50 increased), or sodium chloride (NaCl; P50 unchanged) to rats at a rate of 5 times/wk for 16 wk. At the end of this period, ...
Relevancy Score: Relevancy Score: 141
Testova Lidia - - 2014
The present study reports on a revised kinetic model for alkaline degradation of cellulose accounting for primary peeling/stopping reactions as well as for alkaline hydrolysis followed by secondary peeling. Oxalic acid pretreated cotton linters was utilised as the model substrate for the prehydrolysis-soda anthraquinone process. The main emphasis was investigating ...
Relevancy Score: Relevancy Score: 141
Wongsagonsup Rungtiwa - - 2014
Physicochemical properties of cross-linked tapioca starch (CLTS) with different cross-linking levels and their application as a thickening agent in soups were studied. The CLTS was prepared by cross-linking native tapioca starch suspended in alkaline solution (41.67% (w/w), pH 11) using a mixture (99:1 (w/w) ratio) of sodium trimetaphosphate (STMP) and ...
Relevancy Score: Relevancy Score: 141
Nishi H H Analytical Chemistry Research Laboratory, Tanabe Seiyaku, Co., Ltd., Osaka, - - 1990
The separation of corticosteroids and benzothiazepin analogues by micellar electrokinetic chromatography (micellar EKC) was studied in comparison with capillary zone electrophoresis. The separation of these substances was not successful under neutral and alkaline conditions because they migrated with the same velocity as that of the electroosmotic flow. Micellar EKC with ...
Relevancy Score: Relevancy Score: 141
Lüdi H - - 1984
The state of aggregation of purified sarcoplasmic reticulum adenosine triphosphatase (ATPase) was investigated by high-performance liquid chromatography (LKB TSK-G 4000 SW column) in the presence of various detergents: sodium dodecylsulphate, dodecyl octaethylene glycol monoether (C12E8), sodium deoxycholate, Triton X-100 and myristoylglycerophosphocholine. When the protein (5 mg ml-1) was solubilized with ...
Relevancy Score: Relevancy Score: 141
Nishi H H Analytical Chemistry Research Laboratory, Tanabe Seiyaku, Co., Ltd., Osaka, - - 1989
The retention behaviour of eleven water-soluble vitamins in micellar electrokinetic chromatography (micellar EKC) was investigated in comparison with capillary zone electrophoresis. Sodium dodecyl sulphate (SDS) and sodium lauroylmethyl taurate were used as the anionic surfactants at concentrations of 0.05-0.2 M in micellar EKC. The retention times of cationic substances increased ...
Relevancy Score: Relevancy Score: 141
Wang Y H YH Department of Endocrinology, Peking Union Medical College Hospital, - - 1990
To investigate the effect of rifampicin on the metabolism of hydrocortisone, we measured serum sodium level and blood glucose concentration before lunch in a patient with Addison's disease when treated with hydrocortisone 30 mg/day alone and together with rifampicin 450 mg/day for more than two weeks. We also studied the ...
Relevancy Score: Relevancy Score: 141
Román F F Children's Hospital, Szeged, - - 1990
The sodium and potassium concentrations of the red blood cells and the serum were investigated in 21 children with diabetes mellitus. Measurements were made prior to and 1 and 2 hours following insulin administration. Before insulin treatment, the sodium level in the red blood cells of the diabetes patients was ...
Relevancy Score: Relevancy Score: 141
< 1870 1871 1872 1873 1874 1875 1876 1877 1878 1879 1880 >