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< 1870 1871 1872 1873 1874 1875 1876 1877 1878 1879 1880 >
Kodama Itsuo - - 2005
Differential effects of sodium channel blockers, an I(Kr) blocker (nifekalant) and amiodarone on the spiral-type reentry, were investigated in rabbit hearts by using a high-resolution optical mapping system. Two-dimensional subepicardial layer of left ventricular myocardium with uniform anisotropy was prepared by endocardial cryoablation. During ventricular tachycardia (VT) elicited by cross-field ...
Relevancy Score: Relevancy Score: 141
Benvenuto J A - - 1993
Chemical methods for the degradation of 11 antineoplastic drugs [etoposide, teniposide, bleomycin, mitomycin C, cisplatin, cis-dichloro-trans-dihydroxy-bis(isopropylamine) platinum IV (CHIP), cyclophosphamide, ifosfamide, carmustine, lomustine, and methotrexate] were investigated. The success of the degradation procedures was assessed by HPLC and degree of biological inactivation by mutagenicity assays. The most widely applicable procedure ...
Relevancy Score: Relevancy Score: 141
Gromadzka-Ostrowska J - - 1985
Changes in some trace minerals concentrations (calcium, inorganic phosphorus, magnesium, zinc, iron, copper, sodium and potassium) in blood plasma were investigated during a three-year period in Shetland pony mares. Blood plasma mineral concentrations were determined by the atomic absorption method and colorimetric method. The three-year averages were in micrograms/ml; Na ...
Relevancy Score: Relevancy Score: 141
Metzler C H - - 1987
The escape from the sodium-retaining effects of prolonged mineralocorticoid treatment in animals and humans was first noted over 40 yr ago, but despite intense study the mechanisms responsible for the escape phenomenon have not been identified. Putative "natriuretic hormones" have been proposed to account for the escape phenomenon. To determine ...
Relevancy Score: Relevancy Score: 141
Wehling M - - 1991
A stimulation of the Na(+)-H+ exchanger has been shown in platelets of hypertensive man and lymphocytes of spontaneously hypertensive rats. In the present paper, human mononuclear leukocytes (HML) were investigated in 12 patients with essential hypertension with regard to the activity of the Na(+)-H+ exchanger and HML volume. The swelling ...
Relevancy Score: Relevancy Score: 141
Bernheim J - - 1986
Twenty-five normal pregnant women were studied sequentially at 4-week intervals, beginning from weeks 8-16 until delivery. In eighteen women the study was repeated 6 weeks after delivery. The 24-h urinary excretion of PGE2 and PGF2 alpha, plasma renin activity (PRA), plasma aldosterone and fractional excretion of sodium (FENa) were measured ...
Relevancy Score: Relevancy Score: 141
Gostishchev V K - - 1994
The method of indirect electrochemical detoxification by means of sodium hypochlorite (NaClO) obtained by isotonic NaCl solution electrolysis on a [symbol: see text] device consists in modeling hepatic monooxygenase detoxifying function on cytochrome B-450. Indirect electrochemical detoxification was conducted in more than 200 patients with generalized abdominal pyo-inflammatory processes and ...
Relevancy Score: Relevancy Score: 141
ten Cate J M - - 2008
Caries prevention might benefit from the use of toothpastes containing over 1500 ppm F. With few clinical studies available, the aim of this pH-cycling study was to investigate the dose response between 0 and 5000 ppm F of de- and remineralization of advanced (> 150 microm) enamel lesions. Treatments included ...
Relevancy Score: Relevancy Score: 141
Heidbreder E - - 1990
Recently, it has been reported that atrial natriuretic peptide (ANP) reverses or prevents acute renal failure induced by norepinephrine in rats. Therefore, we tested the hypothesis that vasoconstrictor doses of arginine vasopressin (VP) can induce renal ischemia and that consequent renal dysfunction is reversed by ANP infusion or bolus injections ...
Relevancy Score: Relevancy Score: 141
Keyhani Jacqueline - - 2006
This research reports the sensitivity of a clinical isolate of Enterococcus faecalis to sodium N-lauroylsarcosinate (sarkosyl) and sodium dodecyl sulfate (SDS), as well as the efficiency of these detergents in curing the strain. Compared to Escherichia coli, Enterococcus faecalis was very sensitive to both detergents, with minimum inhibitory concentrations (MIC) ...
Relevancy Score: Relevancy Score: 141
Lalitha J - - 1997
The effect of three different classes of surfactants viz., anionic, cationic and neutral on catalytic activity of potato acid phosphatase (AcPase) was studied. Anionic surfactants bis(2-ethylhexyl) sodium sulfosuccinate (AOT) and sodium dodecyl sulfate (SDS) inhibited AcPase activity completely at 3 mM concentration. The cationic surfactant cetyltrimethylammonium bromide (CTAB), at 3.33 ...
Relevancy Score: Relevancy Score: 141
McBroom M J - - 1998
Rats drinking taurine and hypertonic saline (T + S) develop severe hypernatremia, but rats drinking either T or S alone do not. One hypothesis for this disruption of homeostasis is that the T + S combination interferes with the actions of antidiuretic hormone (ADH). Rats drinking T + S developed ...
Relevancy Score: Relevancy Score: 141
Pandey S K - - 2011
A study was made to find out maximum partitioning of Bacillus licheniformis alkaline phosphatase in different ATPSs composed of different molecular weight of PEG X (X=2000, 4000, 6000) with salts (magnesium sulphate, sodium sulphate, sodium citrate) and polymers (dextran 40, dextran T500). Physicochemical factors such as effect of system pH, ...
Relevancy Score: Relevancy Score: 141
Hecht B - - 1978
Micropuncture studies were performed in rats infused with LiCl to induce stable plasma lithium concentrations of 2--3 mEq/l, or with an equivalent amount of NaCl. In free flow experiments LiCl reduced proximal tubule fractional reabsorption of sodium and potassium. Reduced reabsorption of bicarbonate, as reflected by a decrease in TF/PCl, ...
Relevancy Score: Relevancy Score: 141
Bandini S - - 2001
Ionic Substitution by Electrodialysis is a good alternative to the industrial conversion of sodium salts of phenols into undissociated phenols, conventionally performed through acidification by strong acids. The acidification through electromembranes combines the possibility to achieve high conversion values with the advantage of keeping the process stream separated from the ...
Relevancy Score: Relevancy Score: 141
MacGregor G A - - 1979
Ten women with "idiopathic" edema had sodium and water retention and a rapid gain in weight when their accustomed intake of diuretics was suddenly stopped. The magnitude of these changes was directly related to the levels of plasma-rening activity before withdrawal of diuretics. Nine patients became edematous. Within 10 days ...
Relevancy Score: Relevancy Score: 141
Graham D Y - - 1982
The effect of the addition of sodium bicarbonate, aluminum hydroxide, magnesium hydroxide, calcium carbonate, or cimetidine to supplemental pancreatic enzyme therapy was investigated in patients with severe exocrine pancreatic insufficiency. Steatorrhea was reduced with the administration of three enzyme tablets with meals (73 vs 29 g/24 hr). The coadministration of ...
Relevancy Score: Relevancy Score: 141
Vislobokov A I - - 1992
The influence of taurine (in concentrations of 10(-8) to 10(-2) mole/liter) on the fast sodium, calcium, and potassium, the slow potassium, and the leakage currents of the somatic membrane of the neurons of the pond snail was investigated. A monotonic decrease was demonstrated in the calcium and the slow potassium ...
Relevancy Score: Relevancy Score: 141
Denton D A - - 1990
The influence of systemic or intracerebroventricular (icv) administration of angiotensin II on the intakes of NaCl solution, water, and food was investigated in BALB/c mice. Systemic administration of angiotensin II had little, if any, influence on these ingestive behaviors. On the other hand, icv infusion of angiotensin II at 70 ...
Relevancy Score: Relevancy Score: 141
Omigbodun A O - - 1993
OBJECTIVE: To ascertain the effect of isotonic saline and glucose infusions of oxytocin on neonatal bilirubin levels. METHOD: Eighty-two parturient Nigerian women requiring oxytocin infusion in labor were randomized into two groups receiving 0.9% saline or 5% glucose, respectively. A group of 82 women not requiring oxytocin were recruited for ...
Relevancy Score: Relevancy Score: 141
Weiss Michael - - 2007
This study aims to develop a mechanistic pharmacokinetic model that accounts for the kinetics of tissue binding in order to evaluate the effect of slow binding of digoxin to skeletal muscular Na(+)/K(+)-ATPase in humans. The approach is based on a minimal circulatory model with a systemic transit time density function ...
Relevancy Score: Relevancy Score: 141
Sufrin G - - 1978
Functional aspects of the renin-aldosterone axis were investigated in long-term normotensive and hypertensive renal allograft recipients. Unstimulated plasma renin and aldosterone levels were within control range in all patients and rose significantly in response to sodium depletion. However, no difference in the stimulated renin and aldosterone values between normotensive and ...
Relevancy Score: Relevancy Score: 141
Sardana V - - 2012
To assess the plaque and salivary pH changes at different time intervals in vivo after consumption of a carbonated beverage modified with sodium fluoride and calcium phosphate. Twenty-four subjects aged 18-25 years were recruited and randomly assigned to three groups (group A, original drink Sprite; group B, Sprite with sodium ...
Relevancy Score: Relevancy Score: 141
Knuiman J T - - 1988
We studied the excretion of sodium, potassium, calcium, magnesium, and creatinine in overnight and 24-h urines collected over a period of seven consecutive days from 28 Dutch boys, ages eight and nine years. The correlation coefficients for the relation between true mean overnight and true mean 24-h excretion ranged between ...
Relevancy Score: Relevancy Score: 141
Schloss P - - 1995
Antidepressant drugs block the uptake of serotonin into serotonergic nerve terminals and blood platelets. Here, binding of the tricyclic antidepressant [3H]imipramine to the recombinant rat serotonin transporter SERT1 expressed in human embryonic kidney cells was found to be nonhomogeneous. Scatchard analysis and competition experiments revealed the existence of two distinct ...
Relevancy Score: Relevancy Score: 141
Whitworth J A - - 1997
Abnormalities of cortisol production or metabolism are involved in the genesis of hypertension in Cushing's syndrome, apparent mineralocorticoid excess and liquorice abuse and possibly in chronic renal failure and essential hypertension. We have studied the physiological mechanisms by which cortisol raises blood pressure in short term studies of cortisol administration ...
Relevancy Score: Relevancy Score: 141
Costa Jorge Alberto Vieira - - 2003
To investigate the feasibility of using fresh water from Mangueira Lagoon (Rio Grande do Sul, Brazil) for biomass production in open raceway ponds (0.7 m long, 0.18 m wide, 0.075 m deep) we studied the influence of nutrient addition (carbon as sodium bicarbonate, nitrogen as urea, phosphate, sulfate, ferric iron, ...
Relevancy Score: Relevancy Score: 141
Elliott R J - - 1987
A knowledge of structural and energetic aspects of water- and ion-nucleic acid interactions is essential for the understanding of the role of solvent and counterions in stabilising the various helical forms of nucleic acids. In this study, Monte Carlo computer simulation techniques have been used to predict structural properties of ...
Relevancy Score: Relevancy Score: 141
Pivovarov A S - - 1990
The possible role of cGMP in the regulation of the extinction of the reactions of the RPa4, RPa3, and LPa3 neurons of the edible snail in response to acetylcholine (ACh), applied rhythmically to the soma of the neuron by means of microiontophoresis, has been investigated. It was demonstrated that activators ...
Relevancy Score: Relevancy Score: 141
Gschwantler M - - 1994
A 50-year-old man was admitted to hospital because of vertigo for 3 weeks. He was found to have severe hyponatraemia (107 mmol/l), which was rectified with sodium chloride infusions. Two weeks later he became agitated with confusion and hallucinations. Within a few hours he went into coma. At that time ...
Relevancy Score: Relevancy Score: 141
Diamond H S - - 1977
1. The effect on urate excretion of administration of probenecid and pyrazinamide was observed in normal subjects under control conditions and after induction of uricosuria by exogenous urate loading by ribonucleic acid feeding in seven subjects, by volume loading with hypertonic sodium chloride solution infusion in 11 subjects and by ...
Relevancy Score: Relevancy Score: 141
Grzegorzewska A - - 1990
The paper was performed in order to evaluate the influence of sulfinpyrazone given orally in the doses of 400 mg to 16 uraemic patients during intermittent peritoneal dialysis on transperitoneal and renal transfer of different molecular weight substances. It was shown that sulfinpyrazone causes the increase in dialysate excretion of ...
Relevancy Score: Relevancy Score: 141
Orie N N - - 1993
Sodium-potassium ATPase activity and transmembrane calcium influx in the aortic smooth muscle from control and diabetic rats were assessed indirectly through the measurement of KCl relaxation and contractile responses to CaCl2 in attempts to explain the contractile responses to KCl following streptozotocin-induced diabetes mellitus. There were no significant changes in ...
Relevancy Score: Relevancy Score: 141
Paul Richard V - - 2003
The pharmacology and pharmacokinetics of diuretics are unique among therapeutic drugs. Knowledge of these principles can be used to great advantage in the management of heart failure, whereas ignoring them can lead to either minor or life-threatening adverse consequences. Two major categories of potential therapeutic problems are diuretic resistance and ...
Relevancy Score: Relevancy Score: 141
Zhang X F - - 1994
The mechanism of the photo-oxidation of tyrosine (Tyr) sensitized by sulphonated phthalocyanine at pH 10 in homogeneous aqueous solution or aqueous cetyltrimethylammonium chloride (CTAC) micellar medium was studied by kinetic analysis and laser flash photolysis. Cationic CTAC micelles promote the importance of a type I mechanism in the photo-oxidation of ...
Relevancy Score: Relevancy Score: 141
Owens C W - - 1977
1. A method is described for the serial determination of renal tubular reabsorption of amino acids in the ethanol-anaesthetized rat. It utilizes intravenous radio-labelled inulins, automated amino acid analysis and forced diuresis. 2. Intravenous loading with phenylalanine and infusion of phenylalanine analogues in this preparation decrease reabsorption of endogenous amino ...
Relevancy Score: Relevancy Score: 141
Savage M O - - 1975
Savage, M. O., Wilkinson, A. R., Baum, J. D., Roberton, N. R. C. (1975). Archives of Disease in Childhood, 50, 709. Frusemide in respiratory distress syndrome. The effect of frusemide on urinary volume, urinary sodium excretion, and urinary calcium excretion in 7 premature infants with severe respiratory distress syndrome (RDS) ...
Relevancy Score: Relevancy Score: 141
Patel K P - - 1991
To determine whether central alpha-2 adrenergic mechanisms are involved in the renal nerve mediated natriuresis and diuresis produced by acute volume expansion, urine flow and sodium excretion from innervated and denervated kidneys were measured before and after acute volume expansion (1 ml/min for 20 min) in the presence or absence ...
Relevancy Score: Relevancy Score: 141
Kimura K - - 1998
Sol-gel-derived membranes incorporating crown ether neutral carriers by covalent bonding have been designed for durable, nontoxic neutral carrier-type ion sensors by sol-gel processing using tetraethoxysilane, diethoxydimethylsilane, and their corresponding alkoxysilylated neutral carriers. A tetraphenylborate anion was also bound chemically to the neutral carrier-type sol-gel-derived membranes for suppressing anion interference and ...
Relevancy Score: Relevancy Score: 141
Abad Vivien C - - 2004
Narcolepsy is characterised by excessive daytime sleepiness, usually associated with cataplexy, hypnagogic hallucinations, sleep paralysis and fragmented nocturnal sleep. Although uncommon, it results in significant disability. Most cases occur sporadically, but genetic factors probably form a susceptibility background on which unknown environmental triggers act. The hypocretin system is strongly implicated ...
Relevancy Score: Relevancy Score: 141
Martini A - - 1985
Serum biochemistry was monitored in 50 patients with otosclerosis confirmed surgically. Age distribution was 25 to 50 years (mean:30 years), and the group included 8 men. Constants determined were serum sodium, potassium, chlorine, iron, phosphorus, aluminium, magnesium, copper and alkaline phosphatase. All patients were free from systemic or metabolic disease. ...
Relevancy Score: Relevancy Score: 141
Soares C R - - 2001
Several instruments and materials frequently used in prosthodontics--such as stone casts, dental impressions, interocclusal records--are classified, by the dental literature, as vehicles of transmission of infectious diseases to those who handle them. The present study aims at comparing dimensional alteration, superficial texture and compression resistance of stone dies submitted to ...
Relevancy Score: Relevancy Score: 141
Fang Yapeng - - 2006
The effects of ionic strength, temperature, and pH on the phase separation behavior of type B pigskin gelatin/sodium-type kappa-carrageenan aqueous mixtures were investigated. Depending on the different combinations of temperature and sodium chloride (NaCl) concentration, the mixtures showed compatible, associative, and segregative phase separation behaviors. Additionally, a coexistence of associative ...
Relevancy Score: Relevancy Score: 141
Vieytes M R - - 1993
Sodium channels obtained from rat brain membrane preparations were coated onto microtiter plates and used to develop a direct solid-phase binding assay. The tritiated sodium channel blocker saxitoxin ([3H]-saxitoxin; STX) was used to detect toxins in paralytic shellfish poisoning (PSP) by measuring the competitive displacement of other toxins. With this ...
Relevancy Score: Relevancy Score: 141
Graudins A - - 1997
This report describes a patient with an acute intentional fluoxetine exposure who developed unique cardiovascular and neurovascular toxicity. The patient presented with lethargy and cardiac conduction delays (QRS 110 msec, QTc 458 msec) and developed a delayed seizure. On admission, therapy with intravenous sodium bicarbonate promptly narrowed the QRS to ...
Relevancy Score: Relevancy Score: 141
Mulinacci N - - 2001
In this paper, we discuss the influence of different micellar systems on the degradation of natural anthocyans, either glycosides and aglycones, at pH values ranging from 2.8 to 6.0. The interaction of anthocyanins, in suitable dispersed systems such as negative micelles of sodium dodecylsulphate (SDS), consistently increased their chemical stability ...
Relevancy Score: Relevancy Score: 141
Panasenko O M - - 1999
Liposomes composed of soybean phosphatidylcholine were peroxidized using the reagent sodium hypochlorite or the myeloperoxidase-hydrogen peroxide-Cl- system. Linoleic acid hydroperoxide previously prepared from linoleic acid by means of lipoxidase was incorporated into liposomes. The yield of thiobarbituric acid reactive substances (TBARS) continuously increased with higher amounts of hydroperoxide groups after ...
Relevancy Score: Relevancy Score: 141
Nicholls M Gary - - 2009
Substantial evidence points to the presence in human plasma of an inhibitor of the sodium/potassium pump which plays a central role in the pathophysiology of circulatory disorders, including essential hypertension. Studies from the 1980/90s claimed that this inhibitor was identical or very similar in structure to plant-derived ouabain and was ...
Relevancy Score: Relevancy Score: 141
Marks Joanne - - 2010
Transport of phosphate across intestinal and renal epithelia is essential for normal phosphate balance, yet we know less about the mechanisms and regulation of intestinal phosphate absorption than we do about phosphate handling by the kidney. Recent studies have provided strong evidence that the sodium-phosphate cotransporter NaPi-IIb is responsible for ...
Relevancy Score: Relevancy Score: 141
Stark R J - - 1982
The action of insulin on the resting membrane potential (Em) and intracellular sodium and potassium activities (aNa, aK) of rat soleus muscle fibers was determined by direct intracellular measurements of aNa, aK, and Em using Na-selective, K-selective, and conventional microelectrodes. The use of these microelectrodes allowed us to continuously monitor ...
Relevancy Score: Relevancy Score: 141
< 1870 1871 1872 1873 1874 1875 1876 1877 1878 1879 1880 >