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< 1867 1868 1869 1870 1871 1872 1873 1874 1875 1876 1877 >
Saad W A - - 1995
To determine whether central alpha 1 and alpha 2-adrenergic mechanisms are involved in urinary sodium and potassium excretion and urine volume induced by angiotensin II (ANGII), these renal parameters were measured in volume-expanded Holtzman rats with cannulas implanted into lateral ventricle (LV) and lateral hypothalamus (LH). The injection of ANGII ...
Relevancy Score: Relevancy Score: 141
Lee N - - 1977
The infrared spectrum of a structural lipoprotein from the Escherichia coli outer membrane indicated the lipoprotein had an alpha-helical conformation but no sign for the existence of beta-structures. From circular dichroism spectra of the lipoprotein, the alpha-helical content of the protein was found to be as high as 88% in ...
Relevancy Score: Relevancy Score: 141
Qin Y J - - 1999
In this report, reporter gene beta-galactosidase (LacZ) was chosen to compare two different intramuscular gene transfer methods, direct injection and gene suture. Evidence showed that gene suture can produce a higher foreign gene express efficiency in skeletal muscle compared with the direct injection method. The highly efficient eukaryotic expressing vectors ...
Relevancy Score: Relevancy Score: 141
Díaz-Trelles R - - 2000
Exposure of cultured neurons to nanomolar concentrations of terfenadine prevented the NMDA receptor-mediated early appearance (30min.) of toxicity signs induced by the voltage sensitive sodium channel activator veratridine. Terfenadine also provided an histamine-insensitive protection against delayed neurotoxicity by veratridine (24h), occurring independently of NMDA receptor activation, while not protecting from ...
Relevancy Score: Relevancy Score: 141
Ejiofor O - - 1986
A study has been made of the effects produced on the tensile strength, brittle fracture index (BFI), 'plasto-elasticity' ratio, ER/PC, and yield pressure (1/KH derived from Heckel plots) of sodium salicylate and calcium carbonate as a result of coating their particles with increasing amounts of silicones and polysorbates before subjecting ...
Relevancy Score: Relevancy Score: 141
Zambraski E J - - 1976
Low-level direct renal nerve stimulation increases both renal tubular sodium reabsorption and renal renin secretion rate without changing arterial pressure, glomerular filtration rate, renal blood flow, or intrarenal blood flow distribution. The possibility was considered that intrarenal angiotensin II formation might mediate the antinatriuretic effect by directly enhancing renal tubular ...
Relevancy Score: Relevancy Score: 141
Gaillard C A - - 1989
In 7 healthy humans consuming a 170 mmol sodium diet the effect of the mode of administration of atrial natriuretic factor (human ANF 99-126) on renal function has been investigated, using conventional clearance studies during maximal water diuresis. ANF was administered as four repeated bolus (0.4 microgram/kg) injections and, after ...
Relevancy Score: Relevancy Score: 141
Bell P B PB - - 1983
This paper reports some preliminary findings on the effects of the composition of the detergent extraction medium on the morphological and molecular preservation of the cytoskeleton of Balb/c 3T3 cells as visualized by scanning electron microscopy and SDS-PAGE. Specific variables tested are the concentrations of sodium, potassium, calcium and magnesium ...
Relevancy Score: Relevancy Score: 141
Teramoto Takahide - - 2009
BACKGROUND: Hemolytic uremic syndrome (HUS) is commonly caused by hemorrhagic colitis with Shiga toxin-producing Escherichia coli O-157. Central nervous system (CNS) involvements, including seizures, encephalopathy and brain infarction, are serious complications, but there are no useful scores for the prediction of CNS complications. METHODS: Routine laboratory data at onset of ...
Relevancy Score: Relevancy Score: 141
McBride R K - - 1987
Methotrexate (MTX) was injected intraperitoneally at a dose of 15 mg/kg into adult rats daily for three consecutive days. When compared with saline-injected, ad libitum-fed rats or pair-fed saline-injected rats, MTX decreased unstimulated parotid gland weight, RNA content, and amylase content. RNA content was also decreased in submandibular glands. The ...
Relevancy Score: Relevancy Score: 141
Yokoi K - - 1996
The effects of low dietary rubidium on plasma biochemical parameters and mineral levels in tissues in rats were studied. Eighteen male Wistar rats, weighing about 40 g, were divided into two groups and fed the diets with or without supplemental rubidium (0.54 vs 8.12 mg/kg diet) for 11 wk. Compared ...
Relevancy Score: Relevancy Score: 141
Hassan Ali Awad A - - 2008
The efficacy of treating encysted metacercariae (EMC) of Fasciola gigantica with different concentrations (conc.) of acetic acid, citric acid, cetrimide, potassium permanganate and sodium hydroxide, for 15 & 30 minutes was evaluated. The efficacy of these chemicals on the vitality and infectivity of the EMC was evaluated by the development ...
Relevancy Score: Relevancy Score: 141
Ranson H - - 2004
Resistance to permethrin in an East African population of the major malaria vector, Anopheles gambiae is multifactorial. A mutated sodium channel allele and enhanced insecticide metabolism contribute to the resistance phenotype. We used microsatellite markers to scan the genome for quantitative trait loci (QTL) associated with permethrin resistance. Two major ...
Relevancy Score: Relevancy Score: 141
McKinley M J - - 1979
Intravenous infusion of angiotensin II over the dose range 3-20 microgram/h for 15 min caused a dose-dependent reduction in parotid saliva secretion and increase in arterial blood pressure in conscious sheep. The blood levels of angiotensin II contrived by these infusions were probably within the physiological range for sheep. Infusion ...
Relevancy Score: Relevancy Score: 141
Fujimura A - - 1992
Our previous studies have suggested that the adrenergic nervous system is involved in the mechanism responsible for the time-dependent change in the urinary excretion of furosemide in rats. To examine a potential role of renal nerves in this phenomenon, renal denervation or sham operation was performed using unilaterally nephrectomized rats. ...
Relevancy Score: Relevancy Score: 141
Sen B H - - 1998
OBJECTIVE: The aim of this study was to investigate the effect of titanium tetrafluoride solution on L929 fibroblasts by scanning electron microscopy. Titanium tetrafluoride was then compared with sodium fluoride and acidulated phosphate fluoride. STUDY DESIGN: Cells were treated with fluoride solutions for 1 minute either directly, through a filter ...
Relevancy Score: Relevancy Score: 141
Serova O N - - 1989
After 2-day pre-exposure of rats to sucrose, saccharin or sodium chloride pairing with water (a two-bottle technique) the animals were deprived of liquid for 48 hours. After the deprivation was over, the rats were exposed to the familiar solution (a one-bottle technique) for 15 minutes. The rats which had already ...
Relevancy Score: Relevancy Score: 141
Chrysant S G - - 1979
1. The effects of prolonged high sodium intake (duration 3 months) and meclofenamate were studied in two groups of male spontaneously hypertensive (SH) rats. 2. Group 1 (eight rats) received 1% NaCl in water and served as controls, and group 2 received 1% NaCl in water plus meclofenamate (3.5-4.0 mg ...
Relevancy Score: Relevancy Score: 141
Wehling M - - 1991
A stimulation of the Na(+)-H+ exchanger has been shown in platelets of hypertensive man and lymphocytes of spontaneously hypertensive rats. In the present paper, human mononuclear leukocytes (HML) were investigated in 12 patients with essential hypertension with regard to the activity of the Na(+)-H+ exchanger and HML volume. The swelling ...
Relevancy Score: Relevancy Score: 141
Tomlinson M J - - 1999
Collision-induced dissociation of metal-cationized N-CBZ-Gly-Pro-Gly-Pro-Ala was studied by Fourier transform mass spectrometry. Lithium-, sodium-, potassium- and rubidium-cationized peptide species were generated by matrix-assisted laser desorption/ionization (MALDI) using 2,5-dihydroxybenzoic acid as matrix, together with appropriate metal salts. The experimental mass spectrometric results were interpreted with the aid of Monte Carlo conformational ...
Relevancy Score: Relevancy Score: 141
Ferguson J W - - 2002
An in vitro study was conducted to determine the susceptibility of the yeast Candida albicans to various intracanal irrigants and medications. The minimum inhibitory concentration (MIC) of sodium hypochlorite, hydrogen peroxide, chlorhexidine digluconate, and aqueous calcium hydroxide that is required to kill a standardized inoculum of C. albicans was determined. ...
Relevancy Score: Relevancy Score: 141
Chan S T - - 1982
Early weight gain by starving patients managed with total parenteral nutrition has been regarded as spurious - that is, merely an increase in body water. We designed an experiment to mimic the starved state in which glycogen stores are depleted and sodium intake is very low. The subjects were then ...
Relevancy Score: Relevancy Score: 141
Buerkert J - - 1979
Micropuncture techniques were employed to evaluate the effects of unilateral ureteral obstruction (UUO) of 18 h duration on the function of the terminal collecting duct in weanling rats 90-120 min following release of obstruction. In control animals and after release of UUO, water and sodium reabsorption continued along the terminal ...
Relevancy Score: Relevancy Score: 141
Bolkent S - - 2002
The element compartmentation in cultured rat hepatocytes was studied by electron probe X-ray microanalysis of freeze-dried cryosections after exposure of the cells to the ionophores valinomycin, ionomycin or gramicidin A. The most striking effect of these ionophores is the decrease of the intracellular potassium/sodium ratio from values of approximately 10 ...
Relevancy Score: Relevancy Score: 141
Thibonnier M - - 1983
Plasma aldosterone levels were measured as part of two suppression tests in 31 hypertensive patients on normal sodium diet and without recent treatment. Thirteen patients had essential hypertension, 6 had probable bilateral adrenal hyperplasia and 12 had confirmed Conn's adenoma. In the first test, aldosterone levels were measured in the ...
Relevancy Score: Relevancy Score: 141
Pirog T P - - 2003
Ethanol metabolism in Acinetobacter sp. is limited by the rate of acetate assimilation in a reaction catalyzed by acetyl-CoA synthetase (EC 6.2.1.1). Effects of ions (sodium, potassium, and magnesium), byproducts of ethanol and acetaldehyde oxidation (NADH and NADPH), and pantothenic acid on this enzyme have been studied (sodium, NADH, and ...
Relevancy Score: Relevancy Score: 141
Hannula Minna - - 2008
The CmeABC efflux pump plays an important role in the antimicrobial resistance of Campylobacter jejuni and Campylobacter coli. The aim of this investigation was to study the effect of putative efflux pump inhibitors, phenyl-arginine-beta-naphthylamide (PAbetaN) and 1-(1-naphthylmethyl)-piperazine (NMP), as well as the effect of putative efflux pump inducers, sodium salicylate ...
Relevancy Score: Relevancy Score: 141
Ringelberg M L - - 1979
The study groups using a dentifrice and mouthrinse both containing fluorides, a dentifrice containing stannous fluoride and a mouthrinse containing sodium fluoride, or a mouthrinse containing sodium fluoride with a placebo dentifrice had a 20.7% to 29.0% lower DMF increment than the control group after 30 months. These differences were ...
Relevancy Score: Relevancy Score: 141
Kobashi M - - 2000
The response of gastric motility to the administration of water and saline in the larynx and epiglottis was investigated in urethan-chloralose anesthetized rats. Administration of water inhibited motility of the distal stomach, but 0.15 M NaCl did not induce the inhibitory response. Bilateral sectioning of the superior laryngeal nerve (SLN) ...
Relevancy Score: Relevancy Score: 141
Martini A - - 1985
Serum biochemistry was monitored in 50 patients with otosclerosis confirmed surgically. Age distribution was 25 to 50 years (mean:30 years), and the group included 8 men. Constants determined were serum sodium, potassium, chlorine, iron, phosphorus, aluminium, magnesium, copper and alkaline phosphatase. All patients were free from systemic or metabolic disease. ...
Relevancy Score: Relevancy Score: 141
Quoix E - - 1993
Pretherapeutic prognostic factors were studied retrospectively in 112 consecutive patients diagnosed as small cell lung cancer between January 1st 1986 and December 30th 1990 in our department. Mean age of the population was 59.3, 89.3% were males. Median survival time of the whole population is 11.66 months. It is 15.3 ...
Relevancy Score: Relevancy Score: 141
Pivovarov A S - - 1990
The possible role of cGMP in the regulation of the extinction of the reactions of the RPa4, RPa3, and LPa3 neurons of the edible snail in response to acetylcholine (ACh), applied rhythmically to the soma of the neuron by means of microiontophoresis, has been investigated. It was demonstrated that activators ...
Relevancy Score: Relevancy Score: 141
Epstein F H - - 1975
Potassium adaptation involves the development of the ability of the kidneys to secrete large amounts of potassium into the urine. This is accompanied by an adaptive increase in the specific activity of sodium-potassium-ATPase in the kidney, predominantly in the medulla and the papilla, but also involving the cortex. It is ...
Relevancy Score: Relevancy Score: 141
Brambilla E - - 2001
Since researchers first became aware of the anticaries action of fluoride, they have been investigating the effect of this preventive agent in inhibiting or arresting caries development. Many forms of systemic or topical fluoride have been studied and tested for clinical application. Water, salt, milk fluoridation and the use of ...
Relevancy Score: Relevancy Score: 141
Gagliardi A R - - 1985
The inhibition of osmotic stimulated water flow in the isolated toad bladder by 0.1 mM sodium stibogluconate (pentavalent antimony) is described. Pentavalent antimony on the serosal surface significantly inhibited oxytocin-induced water flow but when the drug was added to the mucosal surface only the effect of low oxytocin concentrations was ...
Relevancy Score: Relevancy Score: 141
Johns A - - 1982
The water content, extracellular space, intracellular water, potassium, sodium and chloride content of oviduct and uterus removed from rabbits in estrus and 24 and 72 h following hCG injection have been determined. Following ovulation, there was an increase in water content of the region of the oviduct corresponding to the ...
Relevancy Score: Relevancy Score: 141
Schloss P - - 1995
Antidepressant drugs block the uptake of serotonin into serotonergic nerve terminals and blood platelets. Here, binding of the tricyclic antidepressant [3H]imipramine to the recombinant rat serotonin transporter SERT1 expressed in human embryonic kidney cells was found to be nonhomogeneous. Scatchard analysis and competition experiments revealed the existence of two distinct ...
Relevancy Score: Relevancy Score: 141
Boldhane Sanjay P - - 2010
Metoprolol succinate (MS) gastroretentive (GR) controlled release system was formulated to increase gastric residence time leading to improved drug bioavailability. Box-Behnken model was followed using novel combinations of sodium alginate (SA), sodium carboxymethylcellulose (NaCMC), magnesium alumino metasilicate (MAS) as independent variables. Floating lag time (Flag), t25, t50, t75, diffusion exponent ...
Relevancy Score: Relevancy Score: 141
Ostrovskaia R U - - 1984
Experiments on rats and mice were made to study the antianamnestic and antihypoxic effects of some GABA derivatives. Cetyl GABA, sodium and lithium hydroxybutyrates and phenibut were shown to be able to decrease the retrograde amnesia caused by electroshock in passive avoidance performance. As regards the degree of the antianamnestic ...
Relevancy Score: Relevancy Score: 141
Kubota M - - 2001
Although ethanolamine plasmalogens (EtnPm) are the predominant phospholipids in neural tissue, their physiological role has not been clarified. The biophysical conformation of EtnPm in the proteoliposome enhances the activity of the sodium-calcium exchanger, which has been proposed to induce intracellular calcium ion accumulation during ischemia and early reperfusion. The levels ...
Relevancy Score: Relevancy Score: 141
Peganov E M - - 1977
Asymmetrical displacement currents (Id) in the frog Ranvier node (R. ridibunda) treated with tetrodotoxin and tetraethylammonium were studied by the use of ramp-voltage pulses. In some experiments both ramp- and step-voltage pulses were used. The net Id consists of two components, one of which Id (I) can be blocked by ...
Relevancy Score: Relevancy Score: 141
Shushakov V V - - 1996
The action of helium (up to 101 abs. atm.) under high pressure on ionic currents through the cellular membrane was studied in experiments on isolated neurons of a gastropod. A method of intracellular dialysis which is new for physiological investigations under hyperbaric conditions was used. A substantial decrease in the ...
Relevancy Score: Relevancy Score: 141
Alieva I B - - 1989
The organization of the centrosome in PK cells has been analysed according to several parameters: the presence of primary cilium, the number of pericentriolar satellites, the presence of striated rootlets, the distance between two centrioles and their orientation as regards the substrate plane. 2,4-Dinitrophenol (DNP), DNP with deoxyglucose (DOG), sodium ...
Relevancy Score: Relevancy Score: 141
Romanelli F - - 2000
OBJECTIVE: To review the efficacy, safety, and proper methods for use of bleach (sodium hypochlorite) as a means of needle disinfection. DATA SOURCES: Controlled studies cited in MEDLINE between 1966 and 1999 using indexing terms: needle, bleach, HIV/AIDS, and disinfection. STUDY SELECTION AND DATA EXTRACTION: Studies were categorized based on ...
Relevancy Score: Relevancy Score: 141
Brunner H R - - 1980
Thirty-nine patients with various types of hypertension were treated by chronic blockage of the angiotensin converting enzyme, i.e. by twice daily administration of captopril, 50 to 200 mg p.o. The blood pressure reduction observed 1 hour following administration of the inhibitor was directly related to the baseline plasma renin activity ...
Relevancy Score: Relevancy Score: 141
Ishihara Keiichi - - 2004
We have shown that sodium salicylate activates the heat shock promoter and induces the expression of heat shock proteins (hsps), with a concomitant increase in the thermotolerance of cells. To determine whether these effects are generally displayed by nonsteroidal anti-inflammatory drugs (NSAIDs), we examined the effects of a cyclooxygenase inhibitor, ...
Relevancy Score: Relevancy Score: 141
Ocaña J A - - 2001
A sensitive time-resolved luminescence method for the determination of trovafloxacin is described. The method is based on the time-resolved luminescence signal from the terbium(III)-trovafloxacin complex, in a micellar solution of sodium dodecyl sulfate (SDS), using a chemical deoxygenation agent (Na(2)SO(3)). The method allows the determination of 20-450 ng ml(-1) of ...
Relevancy Score: Relevancy Score: 141
Bernheim J - - 1986
Twenty-five normal pregnant women were studied sequentially at 4-week intervals, beginning from weeks 8-16 until delivery. In eighteen women the study was repeated 6 weeks after delivery. The 24-h urinary excretion of PGE2 and PGF2 alpha, plasma renin activity (PRA), plasma aldosterone and fractional excretion of sodium (FENa) were measured ...
Relevancy Score: Relevancy Score: 141
Bennett S L - - 2006
OBJECTIVE: To determine reference limits for urinary fractional excretion of electrolytes in Greyhound dogs. METHODS: Urinary fractional excretion was calculated using a spot clearance method preceded by a 16 to 20 hour fast in 48 Greyhound dogs. Raw data analysed using the bootstrap estimate was used to calculate the reference ...
Relevancy Score: Relevancy Score: 141
Sahu S C - - 1994
The extent of DNA damage and lipid peroxidation induced by kaempferol, a polyphenolic flavonoid with a molecular structure similar to quercetin, was studied under aerobic conditions in isolated rat-liver nuclei. Kaempferol induced significant (P < 0.05) concentration-dependent nuclear DNA degradation concurrent with lipid peroxidation; these effects were enhanced by iron(III) ...
Relevancy Score: Relevancy Score: 141
< 1867 1868 1869 1870 1871 1872 1873 1874 1875 1876 1877 >
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