| Werner syndrome - Telomere maintenance and replication processes underlying Werner syndomre | |
Abstract/OtherAbstract
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Werner syndrome is a syndrome which accelerates the normal aging process of an individual. The Syndrome is caused by mutations in the WRN gene. The precise link between this mutated gene and the phenotype is still unclear but much science has been done. By making this report I got an overview on what this link could be. Because of the multifunctional nature of the WRN protein, and the time limit of this project, it was impossible to get a full overview on all the cellular processes that WRN may be a part of but I focused on two important processes that is; DNA replication and telomere maintains. It is widespread accepted that WRN protein plays a role in this processes and lack of efficiency in this processes can cause the aging phenotype. By making this report I have discovered that WRN protein plays a role in many processes and can be considered as being a helpprotein. That is; lack of the WRN protein makes unstable processes. |
Authors
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Larsen, Frederik Weile |
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Contributors
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Andersen, Sofie Dabros |
Publication Detail
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Publisher : - Type : Thesis, Molekylærbiologi / Molecular Biology - not master thesis Format : - |
Date Detail
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2008-06-30, 2008-06-17, 2008-06-17, 2008-06-17 |
Subject
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Werner syndrome, WRN |
Coverage
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Relation
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Source
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Copyright Information
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- |
Other Details
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Languages : en |
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