Document Detail
Use of N-Acetylcolchamine as a Mitotic Poison
Abstract/OtherAbstract :
The anti-mitotic activity of N-acetylcolchamine on Ehrlich ascites cancer cells has been studied in vivo in mice. It has been established that N-acetylcolchamine is an inhibitor of mitosis which, like colchicine, is able to block cell division at the stage of metaphase. Since N-acetylcolchamine is more readily available than colchicine, and is easily obtained in a chemically pure state by acetylation of colchamine, it is recommended for use in various biological studies in place of colchicine., Trans. of Tsitoloqiya (USSR) v9 n10 p1310-1312 1967.
Authors :
Khmelevskiy, V. I., Zusman, F. Y., Khmelevskiy, O. V., Myshkin, N. N.
Contributors :
ARMY FOREIGN SCIENCE AND TECHNOLOGY CENTER CHARLOTTESVILLE VA
Publication Detail :
Publisher :  -     Type :  Text     Format :  text/html    
Date Detail :
1969-04-22
Subject :
TOXICOLOGY, *POISONS, *MITOSIS, USSR, CELL DIVISION, MICE, INHIBITION, IN VIVO ANALYSIS, CELLS(BIOLOGY), CANCER, HISTOLOGY, HISTOLOGICAL TECHNIQUES, COLCHICINE.
Coverage :
-
Relation :
-
Source :
DTIC AND NTIS
Copyright Information :
Approved for public release; distribution is unlimited., Availability: Document partially illegible.
Other Details :
Languages :  en    
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