| Use of N-Acetylcolchamine as a Mitotic Poison | |
Abstract/OtherAbstract
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The anti-mitotic activity of N-acetylcolchamine on Ehrlich ascites cancer cells has been studied in vivo in mice. It has been established that N-acetylcolchamine is an inhibitor of mitosis which, like colchicine, is able to block cell division at the stage of metaphase. Since N-acetylcolchamine is more readily available than colchicine, and is easily obtained in a chemically pure state by acetylation of colchamine, it is recommended for use in various biological studies in place of colchicine., Trans. of Tsitoloqiya (USSR) v9 n10 p1310-1312 1967. |
Authors
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Khmelevskiy, V. I., Zusman, F. Y., Khmelevskiy, O. V., Myshkin, N. N. |
Contributors
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ARMY FOREIGN SCIENCE AND TECHNOLOGY CENTER CHARLOTTESVILLE VA |
Publication Detail
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Publisher : - Type : Text Format : text/html |
Date Detail
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1969-04-22 |
Subject
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TOXICOLOGY, *POISONS, *MITOSIS, USSR, CELL DIVISION, MICE, INHIBITION, IN VIVO ANALYSIS, CELLS(BIOLOGY), CANCER, HISTOLOGY, HISTOLOGICAL TECHNIQUES, COLCHICINE. |
Coverage
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- |
Relation
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- |
Source
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DTIC AND NTIS |
Copyright Information
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Approved for public release; distribution is unlimited., Availability: Document partially illegible. |
Other Details
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Languages : en |
Export Citation
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