Document Detail
Relationship between C-MYC Expression and the Cell Cycle in HL-60 Cells -Flow Cytometric Analysis-
Abstract/OtherAbstract :
By flow cytometric measurement of cellular DNA, c-myc protein and cell volume, we attempted to assess the relationship between c-myc gene expression and the cell cycle in exponentially growing human promyrlocytic leukemia cell line (HL-60). The protein product of c-myc gene was stained by an indirect immunofluorescence method using a specific antiserum to human c-myc protein. Bivariate distributions of cellular DNA, the c-myc protein contents and cell volume demonstrated the direct evidence that the c-myc protein increases with the progression of the cell cycle and then is halved by cell division.
Authors :
Kohsuke Sasaki / Tomoyuki Murakami / Tetsuro Ogino / Manabu Takahashi
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Contributors :
山口大学
Publication Detail :
Publisher :  Yamaguchi University School of Medicine     Type :  text, Departmental Bulletin Paper     Format :  application/pdf    
Date Detail :
2006-03-07
Subject :
Oncogene / c-myc protein / Cell cycle / HL-60 / Flow cytometry, 医学
Coverage :
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Relation :
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Source :
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Copyright Information :
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Other Details :
Languages :  eng    
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