| Relationship between C-MYC Expression and the Cell Cycle in HL-60 Cells -Flow Cytometric Analysis- | |
Abstract/OtherAbstract
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By flow cytometric measurement of cellular DNA, c-myc protein and cell volume, we attempted to assess the relationship between c-myc gene expression and the cell cycle in exponentially growing human promyrlocytic leukemia cell line (HL-60). The protein product of c-myc gene was stained by an indirect immunofluorescence method using a specific antiserum to human c-myc protein. Bivariate distributions of cellular DNA, the c-myc protein contents and cell volume demonstrated the direct evidence that the c-myc protein increases with the progression of the cell cycle and then is halved by cell division. |
Authors
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Kohsuke Sasaki / Tomoyuki Murakami / Tetsuro Ogino / Manabu Takahashi |
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Contributors
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山口大学 |
Publication Detail
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Publisher : Yamaguchi University School of Medicine Type : text, Departmental Bulletin Paper Format : application/pdf |
Date Detail
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2006-03-07 |
Subject
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Oncogene / c-myc protein / Cell cycle / HL-60 / Flow cytometry, 医学 |
Coverage
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Relation
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Source
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Copyright Information
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Other Details
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Languages : eng |
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