| Momordica Foetida (cucurbitacea) A Potential Laxative Granule /Capsule | |
Abstract/OtherAbstract
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There has been a folklore belief that the plant <i>Momordica foetida</i> has a laxative effect. This paper attempted to investigate this claim. The dried extract was granulated with cornstarch mucilage to produce free flowing granules. Capsules containing 500mg of the granules were hand filled. The capsules were evaluated in terms of uniformity of weight and disintegration. Phytochemical analysis of the plant extract showed the presence of alkaloids, saponins and cardenolides. Bioassay of the extract was conducted to verify the laxative effect. Result indicated that the cumulative number of faeces per mouse per hour for different doses increased as the concentration of the medicament increased. This increase was definitely due to the laxative effect of the plant extract. In conclusion, <i>Momordica foetida</i> leaf extract is a potential laxative and could be formulated into a solid dosage form like granules/ capsules to enhance patient compliance. Keywords: <i>Momordica foetida</i> potential laxative. <i>NQJHM</i> Vol. 14 (2) 2004: pp. 189-194 |
Authors
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Odusote, M O; ;, Awaraka, C N; ; |
Contributors
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Publication Detail
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Publisher : Nigerian Quarterly Journal of Hospital Medicine Association of Crop Science, Uganda Type : Peer-Reviewed Article, Format : - |
Date Detail
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2008-02-27 |
Subject
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- , <i>Momordica foetida</i> potential laxative. |
Coverage
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; ; |
Relation
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- |
Source
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Nigerian Quarterly Journal of Hospital Medicine - Nigerian Quarterly Journal of Hospital Medicine; Vol. 14, No. 2 (2004) |
Copyright Information
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Copyright for articles published in this journal is retained by the journal. |
Other Details
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Languages : en |
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