| THE EFFECT OF RAPID CHANGE IN THERMAL ENVIRONMENT ON ABILITY OF HUMAN BLOOD TO ACETYLATE AROMATIC AMINES AND TO INCORPORATE ACETATE-1-C14 INTO LIPIDS. | |
Abstract/OtherAbstract
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Exposure of normal subjects to heat (37C) or cold (4-6C) resulted in changes in the incorporation of acetate-1-C14 into the blood lipids in vitro. Exposure to heat resulted in decreased incorporation and the converse occurred on exposure to cold. No significant difference was found in the responses of a small series of heat acclimated subjects on exposure to heat or cold as compared to paired non-acclimated subjects. However, there was a higher initial incorporation in 4 out of 5 heat acclimated subjects as compared to their non-acclimated controls. Addition of epinerphrine or norepinephrine to whole blood in vitro decreased incorporation of acetate-1-C14 into lipids, while addition of insulin increased incorporation. Addition of triiodothyronine had no consistent effect. Insulin stimulated incorporation of acetate into lipids in blood of diabetic subjects to a lesser extent than in the blood of normal subjects. Removal of plasma resulted in increased incorporation of acetate into lipids. The stimulatory effect of insulin on incorporation was also inhibited by the presence of plasma. (Author) |
Authors
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Blondheim, S. H., Kaufmann, Nathan A. |
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Contributors
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HEBREW UNIV JERUSALEM (ISRAEL) |
Publication Detail
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Publisher : - Type : Text Format : text/html |
Date Detail
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1967-07 |
Subject
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BIOCHEMISRTY, STRESS PHYSIOLOGY, *HEAT TOLERANCE, ACETYLATION, BLOOD CHEMISTRY, RESPONSE(BIOLOGY), ACCLIMATIZATION, NOREPINEPHRINE, IN VITRO ANALYSIS, INSULIN, DIABETES, ACETATES, STIMULATION(PHYSIOLOGY), BLOOD PLASMA, COLD WEATHER TESTS, STRESS(PHYSIOLOGY)., COLD TOLERANCE, TRIIODOTHYRONINE. |
Coverage
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Relation
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Source
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DTIC AND NTIS |
Copyright Information
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APPROVED FOR PUBLIC RELEASE |
Other Details
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Languages : en |
Export Citation
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