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Analysis of risk factors for the development of retinopathy of prematurity in preterm infants at a tertiary referral hospital in South India
Abstract/OtherAbstract :
Background: With the advances in neonatal care, more and more very low birth weight and short gestation age babies are surviving. Along with this population, the incidence and morbidity of retinopathy of prematurity (ROP) is increasing. Analysis of causative factors is imperative. Materials and Methods: All preterm babies with gestational age ≤ 34 week and/or birth weight of ≤ 1750 g who were admitted in Neonatal Intensive Care Unit (NICU) of Indira Gandhi Institute of Child Health (IGICH) were enrolled. All babies underwent detailed ophthalmologic examination with indirect ophthalmoscope. A detailed history was taken regarding maternal risk factors during pregnancy, complications during delivery and early neonatal complications. Babies who developed threshold ROP underwent laser to avascular retina and those who progressed to stage IV or V underwent vitreous surgery. Results: The incidence of ROP was 24%. Administration of oxygen, duration of oxygen delivery, apneic spells, short gestational age, hyaline membrane disease and exchange transfusion were significant risk factors for development of ROP. Sepsis, low birth weight, mechanical ventilation, twin pregnancies and maternal risk factors did not influence ROP. Laser was effective in regressing ROP. Conclusion: Controlling ROP will need team effort and effective delivery of oxygen, quick recognition and management of apneic spells and proper treatment of hyaline membrane diseases.
Authors :
Murthy, Krishna R.
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Subject :
Neišnešiotų naujagimių retinopatija, Vaikų oftalmologija, Retrolental fibroplasia, Pediatric ophtalmology
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Languages :  eng    
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