| The wound healing process: an overview of the cellular and molecular mechanisms. | |
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MedLine Citation:
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PMID: 19930861 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Wound healing remains a challenging clinical problem and correct, efficient wound management is essential. Much effort has been focused on wound care with an emphasis on new therapeutic approaches and the development of technologies for acute and chronic wound management. Wound healing involves multiple cell populations, the extracellular matrix and the action of soluble mediators such as growth factors and cytokines. Although the process of healing is continuous, it may be arbitrarily divided into four phases: (i) coagulation and haemostasis; (ii) inflammation; (iii) proliferation; and (iv) wound remodelling with scar tissue formation. The correct approach to wound management may effectively influence the clinical outcome. This review discusses wound classification, the physiology of the wound healing process and the methods used in wound management. |
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Authors:
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Tomaz Velnar; T Bailey; V Smrkolj |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Journal of international medical research Volume: 37 ISSN: 0300-0605 ISO Abbreviation: J. Int. Med. Res. Publication Date: 2009 Sep-Oct |
Date Detail:
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Created Date: 2009-11-25 Completed Date: 2010-03-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0346411 Medline TA: J Int Med Res Country: England |
Other Details:
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Languages: eng Pagination: 1528-42 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, University Medical Centre Maribor, Maribor, Slovenia. t.valnar.s06@cranfield.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Humans Wound Healing / physiology* Wounds and Injuries / therapy* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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