Document Detail

The whitening effect of enzymatic bleaching on tetracycline.
MedLine Citation:
PMID:  18635305     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Carbamide peroxide and hydrogen peroxide have been used as tooth whitening agents. The aim of this paper was to determine the efficiency of several enzyme-containing whitening systems. A method to determine the rate of 'in vitro' tetracycline whitening was also developed. METHODS: We determined the tetracycline whitening ability of carbamide peroxide and hydrogen peroxide, and the influence of peroxidase and lactoperoxidase on this tetracycline whitening rate. RESULTS: High peroxidase and lactoperoxidase concentrations increased the rate of tetracycline decoloration obtained with carbamide peroxide or hydrogen peroxide. The decoloration rate observed was lower when the glucose/glucose oxidase system was used to generate hydrogen peroxide 'in situ'. The presence of peroxidase increased the decoloration rate of extracted teeth obtained with carbamide. CONCLUSIONS: Enzymes such as peroxidase could be used as whitening catalysts to increase the rate of tetracycline decoloration.
Isabel Gimeno; Pere Riutord; Pedro Tauler; Josep A Tur; Antoni Pons
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-07-16
Journal Detail:
Title:  Journal of dentistry     Volume:  36     ISSN:  0300-5712     ISO Abbreviation:  J Dent     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-08     Completed Date:  2008-12-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0354422     Medline TA:  J Dent     Country:  England    
Other Details:
Languages:  eng     Pagination:  795-800     Citation Subset:  D; IM    
Research Group on Community Nutrition and Oxidative Stress, Research Institute of Health Sciences, University of the Balearic Islands, Palma de Mallorca E-07122, Spain.
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MeSH Terms
Analysis of Variance
Anti-Bacterial Agents / adverse effects*
Drug Combinations
Drug Interactions
Glucose Oxidase / therapeutic use
Hydrogen Peroxide / therapeutic use
Peroxidases / therapeutic use*
Peroxides / therapeutic use
Tetracycline / adverse effects*
Tooth Bleaching / methods*
Tooth Discoloration / chemically induced,  therapy*
Urea / analogs & derivatives,  therapeutic use
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Drug Combinations; 0/Peroxides; 124-43-6/carbamide peroxide; 57-13-6/Urea; 60-54-8/Tetracycline; 7722-84-1/Hydrogen Peroxide; EC Oxidase; EC 1.11.1.-/Peroxidases

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