| The white blood cell scan in orthopedics. | |
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MedLine Citation:
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PMID: 6809387 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A new nuclear scanning technique was found more specific for bone, joint, and soft tissue infections than any previously described scanning technique. The leukocyte scan, whereby a patient's own cells are labeled with a radioactive tagging agent (111In oxine), can distinguish an active infectious process from other pain-inducing conditions. Ninety-seven 111In labeled autologous leukocyte scans were performed in 88 patients. The findings in 17 of 40 patients scanned for possible acute osteomyelitis, six of nine for suspected septic arthritis, and six for possible soft tissue infections, were positive. Subsequent clinical courses verified the infectious nature of these processes in all patients. Patients who had chronic osteomyelitis (14), bony metastases (four patients), heterotopic ossification (three), and degenerative arthritis (two) demonstrated negative findings. Of the seven patients scanned for acute long-bone fractures, one demonstrated positive findings. Nine scans demonstrated positive findings without determined causes. The leukocyte scan is a useful addition to the diagnostic tools of the orthopedic surgeon. |
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Authors:
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S L Propst-Proctor; M F Dillingham; I R McDougall; D Goodwin |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Clinical orthopaedics and related research Volume: - ISSN: 0009-921X ISO Abbreviation: Clin. Orthop. Relat. Res. Publication Date: 1982 Aug |
Date Detail:
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Created Date: 1982-10-12 Completed Date: 1982-10-12 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0075674 Medline TA: Clin Orthop Relat Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 157-65 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Bone Diseases / radionuclide imaging* Bone Neoplasms / radionuclide imaging Female Fractures, Bone / radionuclide imaging Humans Indium / diagnostic use* Infection / radionuclide imaging* Isotope Labeling / methods Joint Diseases / radionuclide imaging* Leukocytes* Male Middle Aged Neoplasm Metastasis Organometallic Compounds* Ossification, Heterotopic / radionuclide imaging Oxyquinoline* / analogs & derivatives* Radioisotopes / diagnostic use* |
| Chemical | |
Reg. No./Substance:
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0/Organometallic Compounds; 0/Radioisotopes; 14514-42-2/indium oxine; 148-24-3/Oxyquinoline; 7440-74-6/Indium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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