| A water-soluble extract from Grifola frondosa, maitake mushroom, decreases lipid droplets in brown adipocyte tissue cells. | |
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MedLine Citation:
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PMID: 19155589 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We investigated the effect of a water-soluble extract from Grifola frondosa, the maitake mushroom, on lipid droplets in brown adipocyte tissue (BAT) cells. This water-soluble extract inhibits the conversion of pre white adipocyte tissue (WAT) cells but does not inhibit that of pre BAT cells. It reduces the amount of accumulated triglycerides (TG) in BAT cells. The glycerol-3-phosphate dehydrogenase (GPDH) activities of BAT cells decreased, but the expression of uncoupling protein 1 (UCP1) levels increased. These results suggest that maitake extract inhibits TG accumulation-related energy metabolism. |
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Authors:
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Katsuhiko Minamino; Yumi Nagasawa; Masaru Ohtsuru |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of nutritional science and vitaminology Volume: 54 ISSN: 0301-4800 ISO Abbreviation: J. Nutr. Sci. Vitaminol. Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2009-01-21 Completed Date: 2009-04-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0402640 Medline TA: J Nutr Sci Vitaminol (Tokyo) Country: Japan |
Other Details:
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Languages: eng Pagination: 497-500 Citation Subset: IM |
Affiliation:
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Department of Food Science and Nutrition, School of Human Environmental Science, Mukogawa Women's University, Nishinomiya, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adipocytes, Brown
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drug effects*,
metabolism Adipocytes, White / drug effects*, metabolism Animals Cell Differentiation / drug effects Glucose / antagonists & inhibitors Glucose Transporter Type 4 / metabolism Glycerolphosphate Dehydrogenase / metabolism* Grifola* Ion Channels / metabolism* Mice Mitochondrial Proteins / metabolism* Plant Extracts / pharmacology* Triglycerides / metabolism* |
| Chemical | |
Reg. No./Substance:
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0/Glucose Transporter Type 4; 0/Ion Channels; 0/Mitochondrial Proteins; 0/Plant Extracts; 0/Triglycerides; 0/mitochondrial uncoupling protein; 50-99-7/Glucose; EC 1.1.-/Glycerolphosphate Dehydrogenase |
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