Document Detail

A vitamin, anabolic, stimulant mixture. Is this form of medication advantageous for debilitated geriatric patients?
MedLine Citation:
PMID:  9752388     Owner:  NLM     Status:  MEDLINE    
Of 32 underweight geriatric patients in a double-blind study, 24 were given a therapeutic mixture containing, per dose, 10 mg of methylphenidate, 2.5 mg of methandrostenolone, and a mixture of B vitamins; 8 patients were given placebo only. After eight weeks of this therapy, there was a significant weight gain in the treated patients. In some cases, this was associated with increased bromsulphalein retention. The number of patients who showed clinically evident increases in strength and vitality was no greater than in the control group. The results lend no support to the use of tonic mixtures instead of separate drugs.
P C Johnson; J Shaw
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Journal of the American Geriatrics Society     Volume:  14     ISSN:  0002-8614     ISO Abbreviation:  J Am Geriatr Soc     Publication Date:  1966 May 
Date Detail:
Created Date:  1998-10-16     Completed Date:  1998-10-16     Revised Date:  2008-03-10    
Medline Journal Info:
Nlm Unique ID:  7503062     Medline TA:  J Am Geriatr Soc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  525-32     Citation Subset:  IM    
Radioisotope Department, Methodist Hospital, Houston, Texas, USA.
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MeSH Terms
Aged, 80 and over
Anabolic Agents / administration & dosage*
Body Weight / drug effects
Central Nervous System Stimulants / administration & dosage*
Confusion / drug therapy
Double-Blind Method
Drug Combinations
Frail Elderly*
Methandrostenolone / administration & dosage*
Methylphenidate / administration & dosage*
Middle Aged
Nursing Homes
Vitamins / administration & dosage*
Reg. No./Substance:
0/Anabolic Agents; 0/Central Nervous System Stimulants; 0/Drug Combinations; 0/Vitamins; 113-45-1/Methylphenidate; 72-63-9/Methandrostenolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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