Document Detail

The very low birth weight infant: the broader spectrum of morbidity during infancy and early childhood.
MedLine Citation:
PMID:  6662919     Owner:  NLM     Status:  MEDLINE    
Neonatal intensive care has improved very low birth weight (less than 1.5 kg) outcome. To evaluate the spectrum of morbidity related to this care, 505 survivors born between 1975 and 1979 were followed during the first three years of life. Transient neurological abnormalities of muscle tone which resolved by two years of age were seen in 40% of children. The incidence of chronic physical disease (lung disease, sequelae of necrotizing enterocolitis, and cholestatic jaundice) was 23% at term, 12% by 8 months, and 3.3% by 20 months. Subnormal weight for age at three years was found in 17% of infants born appropriate for gestational age and 46% of those born small for gestational age. Thirty-three percent of children were rehospitalized during infancy, 10% during their second year, and 10% during their third year of life. Mean IQ was 92.0. In the total population 80.6% were considered normal, 1.7% had major congenital malformations, 10.1% had neurosensory abnormalities, and 7.6% had developmental delay (DQ or IQ less than 80). Close followup care is essential to ensure the eventual adaptation and functional normalization which occurs in the majority of these high-risk infants.
M Hack; B Caron; A Rivers; A A Fanaroff
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of developmental and behavioral pediatrics : JDBP     Volume:  4     ISSN:  0196-206X     ISO Abbreviation:  J Dev Behav Pediatr     Publication Date:  1983 Dec 
Date Detail:
Created Date:  1984-03-12     Completed Date:  1984-03-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8006933     Medline TA:  J Dev Behav Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  243-9     Citation Subset:  IM    
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MeSH Terms
Body Height
Body Weight
Child Development*
Child, Preschool
Cholestasis / diagnosis
Congenital Abnormalities / diagnosis
Enterocolitis, Pseudomembranous / diagnosis
Follow-Up Studies
Infant Mortality
Infant, Low Birth Weight*
Infant, Newborn
Lung Diseases / diagnosis
Nervous System Diseases / diagnosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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