Document Detail


A versatile sugar transferase makes the cut.
MedLine Citation:
PMID:  21295693     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
The nutrient sensor O-GlcNAc transferase modifies proteins with the O-GlcNAc moiety. In this issue, Capotosti et al. (2011) reveal that O-GlcNAc transferase not only glycosylates the cell-cycle regulator host cell factor 1 but activates it through proteolytic cleavage, providing a surprising link between metabolism and epigenetic regulation of the cell cycle.
Authors:
John A Hanover
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cell     Volume:  144     ISSN:  1097-4172     ISO Abbreviation:  Cell     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-07     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413066     Medline TA:  Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  321-3     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Inc. All rights reserved.
Affiliation:
Laboratory of Cellular and Molecular Biology, NIDDK, National Institutes of Health, Bethesda, MD 20892-0851, USA.
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