Document Detail

The venous closing pressure in central retinal vein obstruction.
MedLine Citation:
PMID:  8913125     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the rate of change in the central retinal venous closing pressure in central retinal vein obstruction over time, and its relationship to visual acuity improvement and the development of rubeosis iridis. METHODS: Fifty patients presenting with central retinal vein obstruction of less than three months' duration, between the ages of 40 and 80 years, were reviewed prospectively. The central retinal venous closing pressure was measured by digital ocular compression. Patients were discharged from the study after the six-month visit. RESULTS: All patients had elevated venous closing pressure at presentation, whereas at six months only 24 patients had persistent elevation. Of 16 patients with lowering of the venous closing pressure within four months of onset of central retinal vein obstruction, 11 (69%) had two or more lines of visual acuity improvement. Only two of 10 patients (20%) developing lowering of the venous closing pressure thereafter had visual improvement. No patient developed rubeosis iridis after the venous closing pressure lowered. CONCLUSION: The central retinal venous closing pressure is raised in central retinal vein obstruction to about central retinal arterial diastolic pressure, and is its pathognomonic sign. This sign is easily elicited via digital pressure on the eyelid, and has prognostic significance for visual acuity improvement and the development of rubeosis iridis.
A P Luckie; J J Wroblewski; A C Bird; A M Hamilton; M D Sanders; W Green; N G Slater
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Australian and New Zealand journal of ophthalmology     Volume:  24     ISSN:  0814-9763     ISO Abbreviation:  Aust N Z J Ophthalmol     Publication Date:  1996 Aug 
Date Detail:
Created Date:  1997-02-04     Completed Date:  1997-02-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8505423     Medline TA:  Aust N Z J Ophthalmol     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  233-8     Citation Subset:  IM    
Moorfields Eye Hospital, London.
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MeSH Terms
Aged, 80 and over
Fundus Oculi
Intraocular Pressure
Iris / blood supply
Middle Aged
Prospective Studies
Retinal Vein / physiopathology*
Retinal Vein Occlusion / physiopathology*,  therapy
Venous Pressure
Visual Acuity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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