| The vasopressin system: physiology and clinical strategies. | |
| | |
MedLine Citation:
|
PMID: 16931995 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Vasopressin, synthesized in the hypothalamus, is released by increased plasma osmolality, decreased arterial pressure, and reductions in cardiac volume. Three subtypes of vasopressin receptors, V1, V2, and V3, have been identified, mediating vasoconstriction, water reabsorption, and central nervous system effects, respectively. Vasopressin and its analogs have been studied intensively for the treatment of states of "relative vasopressin deficiency," such as sepsis, vasodilatory shock, intraoperative hypotension, and cardiopulmonary resuscitation. Infusion of vasopressin (0.01-0.04 U/min) decreases catecholamine requirements in patients with sepsis and other types of vasodilatory shock. Bolus application of 1 mg terlipressin, the V1 agonist, reverses refractory hypotension in anesthetized patients and has been studied in patients with septic shock and chronic liver failure. During cardiopulmonary resuscitation, a 40-U bolus dose of vasopressin may be considered to replace the first or second bolus of epinephrine regardless of the initial rhythm. The side effects of vasopressin and its analogs must be further characterized. |
| | |
Authors:
|
Tanja A Treschan; Jürgen Peters |
Related Documents
:
|
10155075 - Resuscitation from cardiogenic shock by direct angioplasty and 23-hour balloon inflatio... 19924275 - A review of cardiogenic shock in acute myocardial infarction. 11288965 - Myocardial bridging of the left anterior descending coronary artery in acute inferior w... 12767535 - Percutaneous coronary revascularization improves the prognosis of patients with cardiog... 17534565 - The effects of facilitated primary pci by guide wire on procedural and clinical outcome... 7656905 - Magnetic resonance angiography in prostatodynia. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Anesthesiology Volume: 105 ISSN: 0003-3022 ISO Abbreviation: Anesthesiology Publication Date: 2006 Sep |
Date Detail:
|
Created Date: 2006-08-25 Completed Date: 2006-09-29 Revised Date: 2007-05-11 |
Medline Journal Info:
|
Nlm Unique ID: 1300217 Medline TA: Anesthesiology Country: United States |
Other Details:
|
Languages: eng Pagination: 599-612; quiz 639-40 Citation Subset: AIM; IM |
Affiliation:
|
Klinik für Anästhesiologie und Intensivmedizin, Germany. tanja.treschan@uni-essen.de |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adrenocorticotropic Hormone
/
secretion Animals Arginine Vasopressin / physiology Blood Pressure Cardiopulmonary Resuscitation Hemostasis Humans Hypertension / drug therapy Hypertension, Portal / drug therapy Neuroendocrine Tumors / surgery Receptors, Vasopressin / antagonists & inhibitors Shock, Septic / drug therapy Vasopressins / physiology*, therapeutic use* Water-Electrolyte Balance |
| Chemical | |
Reg. No./Substance:
|
0/Receptors, Vasopressin; 11000-17-2/Vasopressins; 113-79-1/Arginine Vasopressin; 9002-60-2/Adrenocorticotropic Hormone |
| Comments/Corrections | |
Comment In:
|
Anesthesiology. 2007 Apr;106(4):884; author reply 884-5
[PMID:
17413942
]
Anesthesiology. 2006 Sep;105(3):444-5 [PMID: 16931974 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Opiate pharmacology of intrathecal granulomas.
Next Document: Gender and post-dural puncture headache.