| The value of urinalysis in differentiating acute pyelonephritis from lower urinary tract infection in febrile infants. | |
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MedLine Citation:
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PMID: 7808845 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is an ongoing debate on the best way to screen febrile infants for urinary tract infection. We examined the urinanalysis (UA) findings on admission among infants less than 16 weeks old, with and without acute pyelonephritis (APN), as defined by the dimercaptosuccinic acid (DMSA) renal scan findings, performed during a 57-month period. Forty-nine cases with a positive DMSA scan were compared with 79 negative study cases. A negative UA for leukocytes (< 5 white blood cells/high power field) was found in 4 of 49 (8.1%) cases with APN by DMSA, and in 34 of 79 (43%) cases with a negative DMSA (odds ratio 10.88 (95% confidence interval, 2.31 to 70.3; P < 0.001)). Three of the 4 infants not suspected to have APN by their UA findings would have been admitted for a full sepsis workup based on their clinical presentation and/or their laboratory findings on admission. We conclude that a fresh UA may be a sufficient screening method for the exclusion of APN in infants assessed for fever of no obvious origin. |
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Authors:
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D Landau; M E Turner; J Brennan; M Majd |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: The Pediatric infectious disease journal Volume: 13 ISSN: 0891-3668 ISO Abbreviation: Pediatr. Infect. Dis. J. Publication Date: 1994 Sep |
Date Detail:
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Created Date: 1995-02-02 Completed Date: 1995-02-02 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8701858 Medline TA: Pediatr Infect Dis J Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 777-81 Citation Subset: IM |
Affiliation:
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Department of Nephrology, George Washington School of Medicine, Washington, DC. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Bacterial Infections / complications, diagnosis* Diagnosis, Differential Female Fever of Unknown Origin / etiology* Humans Infant Infant, Newborn Leukocyte Count Male Pyelonephritis / complications, diagnosis*, microbiology, radionuclide imaging Retrospective Studies Succimer Urinalysis* Urinary Tract Infections / complications, diagnosis*, microbiology, radionuclide imaging |
| Chemical | |
Reg. No./Substance:
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304-55-2/Succimer |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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