| The value of PET/CT to assess clinically negative necks. | |
| | |
MedLine Citation:
|
PMID: 22249837 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The aim was to evaluate the efficacy of [(18)F]-2-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) in evaluating metastasis of head and neck squamous cell carcinoma (HNSCC) to the cervical lymph nodes, with specific attention to the efficacy in regard to clinically negative necks. This was a retrospective review of 243 patients with HNSCC between years 2005 and 2007 treated at a comprehensive cancer care institution who underwent pre-operative PET/CT and neck dissection with either an N0 (112 patients) or N+ (131 patients) clinical nodal status. PET/CT findings were correlated with histopathological results of surgical specimens. A majority of the primary sites were oral cavity and oropharynx (70%), followed by larynx, unknown primary and hypopharynx. In the group of 112 patients who underwent 144 neck dissections with N0 nodal status, sensitivity, specificity, positive predictive value (PPV) and negative predictive (NPV) and accuracy were 57, 82, 59, 80 and 74%, respectively. In the group of 131 patients who underwent 169 neck dissections with N+ nodal status, sensitivity, specificity, PPV, NPV and accuracy were 93, 70, 96, 58 and 91%, respectively. PET/CT has a much reduced rate of efficacy for the clinically negative neck compared to the clinically positive neck. PET/CT in its current stage does not appear to offer an advantage in staging the clinically N0 neck due to high rates of false positives and negatives. |
| | |
Authors:
|
Enver Ozer; Barış Naiboğlu; Ryan Meacham; Cherie Ryoo; Amit Agrawal; David E Schuller |
Related Documents
:
|
17380097 - Validated image fusion of dedicated pet and ct for external beam radiation and therapy ... 17726667 - Pet probe-guided surgery. 3278157 - Cyclotrons and radiopharmaceuticals in positron emission tomography. council on scienti... 17869667 - Hypoxia imaging with faza-pet and theoretical considerations with regard to dose painti... 3136627 - Plexiform neurofibromatosis of the mediastinum: ct appearance. 20013607 - examples for asbestos-related findings in hrct - criteria for the assessment of causal ... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-15 |
Journal Detail:
|
Title: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery Volume: - ISSN: 1434-4726 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-1-17 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9002937 Medline TA: Eur Arch Otorhinolaryngol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Department of Otolaryngology-Head and Neck Surgery, Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Comprehensive Cancer Center, The Ohio State University, Columbus, OH, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Functional endoscopic surgery of paranasal fungus ball: clinical outcome, patient benefit and health...
Next Document: Neuronal P/Q-type calcium channel dysfunction in inherited disorders of the CNS.