Document Detail

The value of the prognostic nutritional index in the management of patients with advanced carcinoma of the head and neck.
MedLine Citation:
PMID:  6427139     Owner:  NLM     Status:  MEDLINE    
Nutritional status was evaluated in 50 consecutive patients with advanced squamous cell carcinoma of the head and neck. Using a linear equation developed by Busby , the prognostic nutritional index ( PNI ) was calculated from the serum albumin, triceps skin-fold thickness, serum transferrin, and delayed hypersensitivity reaction. The treatment plan was determined by the patient's attending physician and complications were retrospectively evaluated. The patients were divided into three groups by the value of the PNI . The complication rate was not significantly higher in patients with moderate malnutrition ( PNI between 20% and 39%). However, with severe malnutrition ( PNI greater than 39%), the incidence of iatrogenic complications was prohibitive and 12 of 14 patients were dead within 6 months. We conclude that the PNI is a simple, objective measure of nutritional status that will identify patients at high risk for therapy-related complications and early death.
W J Goodwin; J Torres
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Head & neck surgery     Volume:  6     ISSN:  0148-6403     ISO Abbreviation:  Head Neck Surg     Publication Date:    1984 May-Jun
Date Detail:
Created Date:  1984-07-13     Completed Date:  1984-07-13     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7909027     Medline TA:  Head Neck Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  932-7     Citation Subset:  IM    
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MeSH Terms
Carcinoma, Squamous Cell / complications,  therapy*
Combined Modality Therapy / adverse effects
Head and Neck Neoplasms / complications,  therapy*
Middle Aged
Nutritional Physiological Phenomena*
Patient Care Planning*
Protein-Energy Malnutrition / etiology*,  prevention & control

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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