| The value of PET/CT for preoperative staging of advanced gastric cancer: Comparison with contrast-enhanced CT. | |
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MedLine Citation:
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PMID: 20226612 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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AIM: To date, no data are available on the use of PET/CT for preoperative staging of gastric cancer. We attempted to evaluate the value of PET/CT for preoperative staging of advanced gastric cancer, and to compare the use of PET/CT with contrast-enhanced CT (CECT). MATERIALS AND METHODS: We analyzed PET/CT of 78 patients with surgically proven advanced gastric cancer who had undergone preoperative CECT. Qualitative analysis was conducted by assessing the presence of primary tumors and metastases with PET/CT and CECT. RESULTS: Among 71 patients who underwent a gastrectomy, 69 primary tumors (93%) were diagnosed by PET/CT, while 64 primary tumors (90%) were detected by CECT (p=0.55). For regional lymph node metastasis, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of PET/CT vs. CECT were 41% vs. 25% (p=0.00019), 100% vs. 92% (p=0.31), 100% vs. 98% (p=0.46), 26% vs. 42% (p=0.14), and 51% vs. 72% (p=0.00089), respectively. CONCLUSION: Overall, PET/CT showed comparable diagnostic performance to CECT in diagnosing primary tumors and regional lymph node metastases, though PET/CT was inferior to CECT for the sensitivity and accuracy in diagnosing regional lymph node metastases. Nevertheless, PET/CT would be useful when CECT findings were equivocal due to its high positive predictability. |
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Authors:
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Eun Young Kim; Won Jae Lee; Dongil Choi; Soon Jin Lee; Joon Young Choi; Byung-Tae Kim; Hyung Sik Kim |
Publication Detail:
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Type: Journal Article Date: 2010-03-11 |
Journal Detail:
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Title: European journal of radiology Volume: 79 ISSN: 1872-7727 ISO Abbreviation: Eur J Radiol Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-08-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8106411 Medline TA: Eur J Radiol Country: Ireland |
Other Details:
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Languages: eng Pagination: 183-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon-dong, Gangnam-gu, Seoul 135-710, Republic of Korea. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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