Document Detail

The value of pre-treatment with gonadotrophin releasing hormone (GnRH) analogue in IVF-ET therapy of severe endometriosis.
MedLine Citation:
PMID:  2113929     Owner:  NLM     Status:  MEDLINE    
Controversy concerning the optimal treatment of endometriosis and its related infertility still exists. Thirty-one women with moderate and severe endometriosis, who failed to conceive during previous in-vitro fertilization and embryo transfer (IVF-ET) cycles (protocol A), were re-admitted for the procedure following a period of hormonal suppression with a gonadotrophin releasing-hormone (GnRH) agonist (protocol B). Following GnRH analogue treatment, a significantly higher number of oocytes were recovered (P less than 0.0006); consequently more embryos were transferred and significantly higher clinical pregnancy rates per cycle (P less than 0.0001) were achieved. This difference may be directly related to the beneficial effect of the GnRH analogue on pelvic endometriosis, converting severe cases into mild ones with improved ovarian accessibility and probably oocyte quality.
D Dicker; G A Goldman; J Ashkenazi; D Feldberg; I Voliovitz; J A Goldman
Related Documents :
8501179 - An aggressive philosophy in controlled ovarian stimulation cycles increases pregnancy r...
2056019 - Assessment of the late proliferative phase endometrium by ultrasonography in patients u...
6692959 - Polycystic ovarian syndrome treated by ovarian electrocautery through the laparoscope.
8671379 - Does the absence or presence of seminal fluid matter in patients undergoing ovulation i...
19347389 - First irish birth following ivf therapy using antagonist protocol.
3674549 - Pregnancies without corpus luteum rescue.
635609 - Hodgkin's disease in pregnancy.
116509 - Amniography in second trimester diagnosis of myelomeningocele.
8255449 - Twin birth is not a risk factor for seizures.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  5     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1990 May 
Date Detail:
Created Date:  1990-08-08     Completed Date:  1990-08-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  418-20     Citation Subset:  IM    
Sherman Fertility Institute, Golda Meir Medical Centre, Hasharon Hospital, Petah Tikva, Israel.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Buserelin / therapeutic use*
Embryo Transfer*
Endometriosis / complications*
Fertilization in Vitro*
Infertility, Female / drug therapy*,  etiology
Oocytes / drug effects
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Endocrine changes in women conceiving during treatment with an LHRH agonist.
Next Document:  Serum levels of pregnancy-associated endometrial alpha 2-globulin (alpha 2-PEG), a glycosylated beta...