Document Detail


The value of platelet-associated IgG in predicting the efficacy of splenectomy in autoimmune thrombocytopenia.
MedLine Citation:
PMID:  6682240     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a prospective study, the hypothesis of whether the quantitative determination of platelet-associated IgG (PAIgG) in patients with chronic autoimmune thrombocytopenic purpura (ATP) can predict the efficacy of splenectomy, was investigated. PAIgG levels were repeatedly determined in 16 patients with definite ATP pre- and postsplenectomy, and related to platelet counts and platelet mean life span. It was found that patients with an immediate remission after splenectomy tended to have lower PAIgG levels (less than 6%) than failures, but this difference was not statistically significant. We conclude that PAIgG is of limited value for the prediction of the efficacy of splenectomy in ATP.
Authors:
W Kayser; C Mueller-Eckhardt; G Mueller-Eckhardt
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Scandinavian journal of haematology     Volume:  30     ISSN:  0036-553X     ISO Abbreviation:  Scand J Haematol     Publication Date:  1983 Jan 
Date Detail:
Created Date:  1983-05-27     Completed Date:  1983-05-27     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0404507     Medline TA:  Scand J Haematol     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  30-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Autoimmune Diseases / immunology*,  therapy
Blood Platelets / immunology*
Child
Female
Humans
Immunoglobulin G / analysis*
Male
Middle Aged
Platelet Count
Purpura, Thrombocytopenic / immunology*,  therapy
Splenectomy*
Chemical
Reg. No./Substance:
0/Immunoglobulin G

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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