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The value of the middle cerebral to umbilical artery Doppler ratio in the prediction of neonatal outcome in patient with preeclampsia and gestational hypertension.
MedLine Citation:
PMID:  22439055     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To investigate the diagnostic value of MCA/UA pulsatility index ratio for the prediction of adverse perinatal outcome in the fetuses with preeclampsia and gestational hypertension.
MATERIALS AND METHODS: We included in the study 738 patients recovered in our Hospital with the diagnosis of preeclampsia and gestational hypertension, from January 2006 to December 2009. All the patients underwent accurate color Doppler velocimetry examination. The study population was divided into two groups depending on the normal or abnormal values of MCA/UA pulsatility index ratio.Outcome variables were intrauterine and early neo natal death, admission to the neonatal intensive care unit and the duration of treatment, Apgar score below 7 at 5 minutes,cesarean delivery for fetal distress, gestational age at delivery, neonatal birth weight, IUGR.
RESULTS: We divided the study population into two groups depending on normal or abnormal value of MCA/UA pulsatility index ratio. In 314 patients we found abnormal values of MCA/UA pulsatility index ratio. Neonates of mothers with abnormal values of MCA/UA pulsatility index ratio had significantly lower gestational age at delivery (34.8 versus 38.4, P<0.0001), lower birth weight (2174.6 g versus 3215.0g, P<0.001), significantly greater risk for perinatal death (30.8% versus 0.23%, P<0.0001) significantly greater risk of admission to intensive care unit (77.8% versus 47.4%, P<0.0001), longer duration of treatment in NICU (10.6 days versus 6.5 days, P<0.0001), greater rate of cesarean delivery for fetal distress (76.7% versus 62.5%,P<0.0001), a great number of neonates with low Apgar score at 5 minute (61.9% versus 22.4%, P<0.0001) greater rate of cesarean delivery for fetal distress (71.9% versus 62.5%,P<0.0001), a great number of fetuses IUGR (7.18% versus 1.76%,P<0.0001).
CONCLUSION: ACM/UA pulsatility index ratio is a very good predictor of adverse outcome in the fetuses of women with preeclampsia and gestational hypertension.
Authors:
Rozeta Shahinaj; Nikita Manoku; Enriketa Kroi; Ilir Tasha
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of prenatal medicine     Volume:  4     ISSN:  1971-3290     ISO Abbreviation:  J Prenat Med     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2012-03-22     Completed Date:  2012-08-23     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101522906     Medline TA:  J Prenat Med     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  17-21     Citation Subset:  -    
Affiliation:
Obstetrics - Gynecologic University Hospital"Queen Geraldine" of Tirana, Albanie.
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