Document Detail


The value of lookback to understanding blood-borne infectious diseases: the New South Wales' HIV experience.
MedLine Citation:
PMID:  12415517     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article describes the methods used by the New South Wales Division of the Australian Red Cross Blood Service (ARCBS-NSW) to conduct human immunodeficiency virus (HIV) lookback, assesses the success and limitations of the different methods used, and discusses the results obtained. This article shows that an important outcome of the HIV lookback undertaken by the ARCBS-NSW was the establishment and maintenance of an observational database. This database became an integral part of several research projects that contributed significantly to understanding factors influencing the rate of progression of HIV to acquired immunodeficiency virus and knowledge of HIV pathogenesis in general. This article argues that if lookback is extended beyond its original function of identifying transfusion-infected recipients and the implicated donors to create and maintain a linked register of these recipients and donors, the information obtained in such an observational database can be used to describe the natural history of transfusion-transmitted infectious diseases and can contribute to the research necessary to the understanding of disease pathogenesis.
Authors:
Jennifer C Learmont; Rosemary S Phillips; Ian J Bickerton
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Transfusion medicine reviews     Volume:  16     ISSN:  0887-7963     ISO Abbreviation:  Transfus Med Rev     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-11-04     Completed Date:  2003-06-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8709027     Medline TA:  Transfus Med Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  315-24     Citation Subset:  IM    
Copyright Information:
Copyright 2002, Elsevier Science (USA)
Affiliation:
Australian Red Cross Blood Service-North East Region, Parameter, Australia. jlearmont@arcbs.org.au
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MeSH Terms
Descriptor/Qualifier:
Australia
Blood Donors
Blood-Borne Pathogens
Databases, Factual*
HIV Infections / etiology,  transmission*
Humans
Infection / etiology,  transmission
Red Cross*
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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