| The value of immunoscintigraphy in the detection of recurrent colorectal cancer. | |
| | |
MedLine Citation:
|
PMID: 11711899 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The aim of this prospective study was to determine whether anti-carcinoembryonic antigen (anti-CEA) scintigraphy is a useful additional technique in the diagnosis recurrence of colorectal cancer. Forty patients with suspected recurrence of colorectal cancer, underwent immunoscintigraphy (IS) and helical computed tomography (CT) in the 2 weeks before surgery. Surgical findings were used to evaluate the performance of the imaging techniques. Suspected areas on IS and CT were systematically explored. Helical CT was found to be superior to IS for the liver, the sensitivity and specificity of CT being 100% and 90%, respectively, vs 53% and 100% for IS. However, IS was better than CT for the detection of extra-hepatic abdominal recurrence: sensitivity and specificity of IS were 100 and 82% respectively vs 33 and 82% for CT. Seven cases of peritoneal carcinomatosis were overlooked by helical CT. Our results indicate that IS improves detection of extra-hepatic abdominal recurrence of colorectal cancer. Immunoscintigraphy is valuable as a guide to the treatment strategy and operative procedures. |
| | |
Authors:
|
F Baulieu; P Bourlier; B Scotto; C Mor; V Eder; L Picon; L De Calan; E Dorval; J M Pottier; J L Baulieu |
Related Documents
:
|
15789609 - Comparison of helical and cine acquisitions for 4d-ct imaging with multislice ct. 1682289 - Gallstone susceptibility to in vitro fragmentation by a 480-nm pulsed dye laser. correl... 9089589 - Low-contrast resolution in volumetric x-ray ct--analytical comparison between conventio... 10845479 - Comparing mr imaging and ct in the staging of gastric carcinoma. 1457539 - Three-dimensional display of hepatic venous anatomy generated from spiral computed tomo... 10415249 - Intrahepatic arterioportal shunt: helical ct findings. 17275759 - Characterization of acute and subacute radiofrequency ablation lesions with nonenhanced... 20098019 - Long-term follow up of patients with good outcome after intra-arterial thrombolysis for... 16432969 - Diagnosis and management of tracheal stenosis. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Nuclear medicine communications Volume: 22 ISSN: 0143-3636 ISO Abbreviation: Nucl Med Commun Publication Date: 2001 Dec |
Date Detail:
|
Created Date: 2001-11-16 Completed Date: 2002-02-13 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 8201017 Medline TA: Nucl Med Commun Country: England |
Other Details:
|
Languages: eng Pagination: 1295-304 Citation Subset: IM |
Affiliation:
|
Department of Nuclear Medicine, University Hospital Trousseau, F37044-Chambray les Tours, France. fbaulieu@med.univ-tours.fr |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adenocarcinoma
/
radionuclide imaging,
surgery Adult Aged Antibodies, Monoclonal / diagnostic use Carcinoembryonic Antigen / blood, immunology Colorectal Neoplasms / radiography, radionuclide imaging*, radiotherapy, surgery Female Humans Liver Neoplasms / radiography, secondary Male Middle Aged Radioimmunodetection / methods Rectal Neoplasms / radionuclide imaging, surgery Recurrence Technetium / therapeutic use Tissue Distribution Tomography, X-Ray Computed Tumor Markers, Biological / blood |
| Chemical | |
Reg. No./Substance:
|
0/Antibodies, Monoclonal; 0/Carcinoembryonic Antigen; 0/Tumor Markers, Biological; 7440-26-8/Technetium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Can scintimammography with (99m)Tc-MIBI identify multifocal and multicentric primary breast cancer?
Next Document: Assessment of adenosine, arbutamine and dobutamine as pharmacological stress agents during (99m)Tc-t...