| The value of fallopian tube sperm perfusion in the management of mild-moderate male factor infertility. | |
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MedLine Citation:
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PMID: 22356757 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate whether fallopian tube sperm perfusion (FSP) would improve pregnancy rates compared with standard intrauterine insemination (IUI) in cases of male factor infertility. METHODS: In a randomized controlled trial at a university teaching hospital in Egypt, 120 couples with mild or moderate male factor infertility underwent a mild controlled ovarian stimulation protocol (clomiphene citrate plus human menopausal gonadotropin). Women were randomly allocated to group 1 (FSP via Foley catheter with 4mL of inseminate) or group 2 (standard IUI with 0.5mL of inseminate) (n=60 for both). The main outcome measure was clinical pregnancy rate. RESULTS: There were no significant differences between the groups in terms of baseline clinical characteristics, semen parameters, or characteristics of stimulation cycles. The pregnancy rate was significantly higher in group 1 than in group 2 (16 [26.7%] vs 7 [11.7%]; P<0.04). There was no significant difference in the incidence of multiple pregnancy, abortion, or ectopic pregnancy between the groups. CONCLUSION: Fallopian tube sperm perfusion is an effective technique in the management of mild-moderate male factor infertility and should, therefore, be considered before resorting to more sophisticated techniques of assisted reproduction. |
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Authors:
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Waleed El-Khayat; Akmal El-Mazny; Nermeen Abou-Salem; Aly Moafy |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-2-20 |
Journal Detail:
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Title: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics Volume: - ISSN: 1879-3479 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-2-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0210174 Medline TA: Int J Gynaecol Obstet Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo, Egypt. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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