| The value of the electrocardiogram in risk assessment in primary prevention: experience from the West of Scotland Coronary Prevention Study. | |
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MedLine Citation:
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PMID: 17069838 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Electrocardiograms (ECGs) were recorded at baseline, annually thereafter, and at run-out in the West of Scotland Coronary Prevention Study to which 6595 men aged from 45 to 65 years on entry were recruited. The baseline ECGs were analyzed with respect to (a) the primary end point of the study, namely, fatal or nonfatal myocardial infarction (MI) and (b) all-cause mortality. In addition, incident MIs were reviewed to determine those detected by ECG only. Heart rate, indexed left ventricular mass, frontal T axis, and T amplitude in lead I were all significantly predictive with respect to the primary end point in a multivariate analysis. With respect to all-cause mortality, minor ST-T changes, 10-second heart rate variability, and frontal T axis were similarly predictive. Of 355 incident MIs, 47.3% were silent or unrecognized and detected by ECG only. A simple ECG-based risk prediction equation for fatal and nonfatal MI is introduced. |
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Authors:
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P W Macfarlane; J Norrie; |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial Date: 2006-10-25 |
Journal Detail:
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Title: Journal of electrocardiology Volume: 40 ISSN: 1532-8430 ISO Abbreviation: J Electrocardiol Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2006-12-25 Completed Date: 2007-01-16 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0153605 Medline TA: J Electrocardiol Country: United States |
Other Details:
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Languages: eng Pagination: 101-9 Citation Subset: IM |
Affiliation:
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Division of Cardiovascular and Medical Sciences, University of Glasgow, Scotland, UK. peter.w.macfarlane@clinmed.gla.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Anticholesteremic Agents / therapeutic use Diagnosis, Computer-Assisted / methods* Electrocardiography / methods*, statistics & numerical data* Humans Incidence Longitudinal Studies Male Mass Screening / methods, statistics & numerical data Middle Aged Myocardial Infarction / diagnosis*, mortality*, prevention & control Outcome Assessment (Health Care) Pravastatin / therapeutic use Primary Prevention / methods, statistics & numerical data Prognosis Proportional Hazards Models Reproducibility of Results Risk Assessment / methods* Risk Factors Scotland / epidemiology Sensitivity and Specificity Survival Analysis* Survival Rate Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Anticholesteremic Agents; 81093-37-0/Pravastatin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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