Document Detail


The value of D-dimer test in the diagnosis of patients with nontraumatic acute abdomen.
MedLine Citation:
PMID:  20209391     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: A patient with acute abdominal pain requires rapid evaluation. In these patients, it is very important to distinguish between surgical and nonsurgical pathology. Our aim was to compare the accuracy of the leukocyte count and D-dimer test in the diagnosis of acute abdomen. METHODS: In this prospective study, 225 patients admitted to the emergency unit due to nontraumatic acute abdomen between June 2006 and November 2007 were evaluated. The patients were divided into two groups: Group 1 patients who needed immediate laparotomy and Group 2 patients who did not. Age, gender, leukocyte count, D-dimer level, causes of acute abdominal pain, and operative findings were investigated. P values of <0.05 were considered statistically significant. RESULTS: There was a positive correlation between the plasma D-dimer level and leukocyte count. D-dimer acted similarly to the leukocyte count in emergency abdominal conditions. The area under the receiver operating characteristic curve was statistically higher with the D-dimer test (p<0.0001). Additionally, in patients needing immediate laparotomy, the sensitivity of the D-dimer test was 95.7% versus 74.8% for leukocyte counts. CONCLUSION: In a patient with acute abdomen, D-dimer test may be a strong alternative or an adjuvant to the leukocyte count.
Authors:
Hizir Yakup Akyildiz; Erdo?an S?z?er; Alper Akcan; Can K???k; Tarik Artis; Ismail Biri; Namik Yilmaz
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES     Volume:  16     ISSN:  1306-696X     ISO Abbreviation:  Ulus Travma Acil Cerrahi Derg     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-03-08     Completed Date:  2010-03-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101274231     Medline TA:  Ulus Travma Acil Cerrahi Derg     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  22-6     Citation Subset:  IM    
Affiliation:
Department of General Surgery, Erciyes University Faculty of Medicine, Kayseri, Turkey. hyakyildiz@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Abdomen, Acute / blood,  diagnosis*,  surgery
Abdominal Pain / diagnosis,  surgery
Acute Disease
Diagnosis, Differential
Female
Fibrin Fibrinogen Degradation Products / analysis*
Humans
Laparotomy / utilization
Leukocyte Count / utilization*
Male
Middle Aged
Predictive Value of Tests
Prospective Studies
ROC Curve
Chemical
Reg. No./Substance:
0/Fibrin Fibrinogen Degradation Products; 0/fibrin fragment D

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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