Document Detail


The value of 18-FDG PET/CT imaging in a patient with atypical metastatic colorectal cancer--case report: 18-FDG PET/CT in colorectal cancer.
MedLine Citation:
PMID:  20099747     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUNDS:Cancer metastasis to skeletal muscle is very rare. Lung cancer, renal cell carcinoma and malignant melanoma have been reported as the most frequent primary tumours. Diagnosis of muscle metastasis from other primary cancer sites is more than problematic. CASE: In this paper we report a case of metastasis of colorectal cancer in a 44-year-old man who underwent left-sided hemicolectomy due to the tumour mass in his left colic flexure followed by liver metastasectomy and cryocautery of the non-resectable metastasis in the VII segment. Subsequently, the patient was treated with two lines of chemotherapy. However, shortly after initiation of the second chemotherapy line he started to suffer from unbearable pain in the lumbosacral region. Neither a whole spinal cord MRI nor abdominal CT scan and scintigraphy explained the origin of the pain. Finally, PET/CT examination clarified the origin of the pain and showed massive hypermetabolic metastatic lesions in the muscles, further confirmed by autopsy. CONCLUSION:Thus, among the different imaging techniques, FDG PET/CT enables the detection of metabolically highly active tumour cells, undetectable by other conventional imaging means.
Authors:
Z Hlavat?; N Pazderov?; P Povinec; P Paul?ny; A Majidi; P Fiala; P Martanovic; T S?lek
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Klinick? onkologie : casopis Cesk? a Slovensk? onkologick? spolecnosti     Volume:  22     ISSN:  0862-495X     ISO Abbreviation:  Klin Onkol     Publication Date:  2009  
Date Detail:
Created Date:  2010-01-26     Completed Date:  2010-03-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9425213     Medline TA:  Klin Onkol     Country:  Czech Republic    
Other Details:
Languages:  eng     Pagination:  284-7     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, National Cancer Institute, Bratislava, Slovak Republic. zuzana.hlavata@nou.sk
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MeSH Terms
Descriptor/Qualifier:
Adult
Colorectal Neoplasms / pathology*
Fluorodeoxyglucose F18 / diagnostic use*
Humans
Male
Muscle Neoplasms / diagnosis*,  secondary*
Positron-Emission Tomography*
Radiopharmaceuticals / diagnostic use*
Tomography, X-Ray Computed*
Chemical
Reg. No./Substance:
0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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