| A validation study of the Chinese wearing off questionnaire 9-symptom for Parkinson's disease. | |
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MedLine Citation:
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PMID: 21507565 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: Development of wearing off (WO) often goes unnoticed for both patients with Parkinson's disease (PD) and physicians due to the complexity of this phenomenon. A brief 9-symptom WO questionnaire (WOQ-9) was recently found to be highly sensitive in its detection. We aimed to validate a Chinese version WOQ-9 (CWOQ-9) among Chinese patients with PD. METHODS: We recruited 101 literate Chinese PD patients among 4 different neurology or movement disorders clinics in Hong Kong to participate in this study by completing the CWOQ-9. Clinical judgment by the specialists was considered the gold standard for diagnosing WO. RESULTS: The mean age (±SD) of the patients was 61 (±9) years and 35 (34.7%) of them were female. The disease duration was 7.4 (±5.4) years and 69 (68.3%) of them were diagnosed clinically to have WO by the specialists. The positive and negative predictive values, sensitivity and specificity of CWOQ-9 were 86%, 71%, 87%, and 69% respectively. The area under curve (AUC) was 0.78 (p<0.001). CONCLUSION: This simple patient questionnaire is a valid tool for the detection of WO among Chinese PD patients. |
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Authors:
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A Chan; Y F Cheung; M Au Yeung; J Yeung; T H Chung; K L Tsang; J Chan; C Lau; P Kwan; Sheng-Han Kuo; V Mok |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-18 |
Journal Detail:
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Title: Clinical neurology and neurosurgery Volume: - ISSN: 1872-6968 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7502039 Medline TA: Clin Neurol Neurosurg Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011. Published by Elsevier B.V. |
Affiliation:
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Department of Medicine and Therapeutics, Prince of Wales Hospital, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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