Document Detail


The utilization of protein and energy during lactation in the rat, with particular regard to the use of fat accumulated in pregnancy.
MedLine Citation:
PMID:  7115665     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
1. The deposition of fat during pregnancy and its subsequent mobilization during lactation was studied in the rat. The utilization of protein during lactation was also investigated. 2. Fat accumulation was rapid and continuous from early pregnancy. Approximately one-third was deposited subcutaneously, the remainder being stored in central depots. 3. The volume of milk produced during lactation was varied by offering protein at two concentrations from day 2 post partum. Optimum lactation was achieved with a high-protein diet. The dams lost no body protein, but 60% of the total body fat was mobilized, despite a marked increase in food consumption. On a low-protein diet, food intake did not rise during lactation. Some body protein was catabolized and, again, 60% of the fat was mobilized although milk output, as judged by the gain in carcass energy of their pups, was reduced to approximately one-third of optimum. 4. Protein was used more efficiently by lactating rats, when compared with virgin controls. 5. We conclude that fat stored during pregnancy makes a major contribution to the energy costs of lactation, and that its mobilization is under hormonal rather than dietary control.
Authors:
D J Naismith; D P Richardson; A E Pritchard
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The British journal of nutrition     Volume:  48     ISSN:  0007-1145     ISO Abbreviation:  Br. J. Nutr.     Publication Date:  1982 Sep 
Date Detail:
Created Date:  1982-12-03     Completed Date:  1982-12-03     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0372547     Medline TA:  Br J Nutr     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  433-41     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adipose Tissue
Animals
Animals, Newborn
Argininosuccinate Synthase / metabolism
Body Composition
Body Weight
Dietary Proteins / metabolism*
Eating
Female
Lactation*
Lipid Metabolism
Lipid Mobilization*
Liver / enzymology
Pregnancy
Pregnancy, Animal*
Rats
Rats, Inbred Strains
Chemical
Reg. No./Substance:
0/Dietary Proteins; EC 6.3.4.5/Argininosuccinate Synthase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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