Document Detail


The utility of thrombophilia testing in pregnant women with thrombosis: fact or fiction?
MedLine Citation:
PMID:  18572147     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Women who either present with an episode of acute venous thrombosis in pregnancy or who have a history of venous thrombosis who present for prenatal care often undergo testing for inherited thrombophilia. The rationale for screening may include questions about whether screening for inherited thrombophilias can help to alter anticoagulation plans in a pregnancy complicated by venous thrombosis, whether patients with a history of venous thrombosis who present for care in a subsequent pregnancy require anticoagulation and at what intensity, whether knowledge of thrombophilia changes the duration and intensity of anticoagulation outside pregnancy, and whether screening of family members is warranted. Data regarding these issues are reviewed, controversies surrounding thrombophilia testing in this setting are discussed, and clinical recommendations are made.
Authors:
Christina M Scifres; George A Macones
Related Documents :
22015867 - Excessive weight gain in term twin pregnancies: examining the 2009 institute of medicin...
15711747 - Venous thromboembolism during pregnancy is not associated with persistent elevated acti...
25348257 - Cerclage outcome by the type of suture material (cots): study protocol for a pilot and ...
10610007 - Low-molecular-weight heparins in pregnancy.
11777517 - Impact of fetal reduction on the incidence of gestational diabetes.
1674477 - Invasive techniques for fetal diagnosis in multiple pregnancy.
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2008-06-24
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  199     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-10-20     Completed Date:  2008-11-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  344.e1-7     Citation Subset:  AIM; IM    
Affiliation:
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO 63110, USA. scifresc@wustl.edu
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Anticoagulants / administration & dosage
Female
Genetic Predisposition to Disease
Humans
Incidence
Methylenetetrahydrofolate Reductase (NADPH2) / genetics
Physician's Practice Patterns
Pregnancy
Pregnancy Complications, Hematologic / epidemiology,  etiology*,  prevention & control
Pregnancy Outcome
Puerperal Disorders / prevention & control
Risk Assessment
Thrombophilia / complications,  diagnosis*,  genetics
Venous Thromboembolism / epidemiology,  etiology*,  prevention & control
Chemical
Reg. No./Substance:
0/Anticoagulants; EC 1.5.1.20/Methylenetetrahydrofolate Reductase (NADPH2)

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Classification and evaluation of microfluidic devices for continuous suspension fractionation.
Next Document:  The electrical coupling confers to a network of interneurons the ability of transmitting excitatory ...