Document Detail

The utility of modified Butler-Leggett criteria for right ventricular hypertrophy in detection of clinically significant shunt ratio in ostium secundum-type atrial septal defect in adults.
MedLine Citation:
PMID:  19959184     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: This study was performed to test the hypothesis that there exists a correlation between the Butler-Leggett (BL) criterion for right ventricular hypertrophy on the electrocardiogram and the Qp/Qs shunt ratio in adults with ostium secundum atrial septal defects (ASDs). METHODS: Demographic, cardiac catheterization, ASD closure, and electrocardiographic data were acquired on 70 patients with secundum ASDs closed percutaneously. Simple linear regression and logistic regression models were created to test the hypothesis. RESULTS: The mean Qp/Qs ratio and BL criterion value were 1.61 +/- 0.46 and 0.11 +/- 0.41, respectively. The BL criterion values correlated with shunt ratios (r(2) = 0.11 and P = .004). A BL criterion value greater than 0 mV predicted a significant shunt ratio (Qp/Qs > or = 1.5) (odds ratio, 4.8; 95% confidence interval, 1.3, 18.1; P = or <.0001) with a sensitivity of 0.68 and specificity of 0.65. CONCLUSION: Our results indicate that there is limited utility of the BL criterion at detecting right ventricular volume overload, although a BL criterion value greater than 0 mV being used to identify patients with significant intracardiac shunts yielded a sensitivity of 0.68 and specificity of 0.65.
Adeel M Siddiqui; Zainab Samad; Nina Hakacova; James Kinsella; Cary Ward; Michael White; Anna Lisa C Crowley; Galen S Wagner; J Kevin Harrison
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Publication Detail:
Type:  Journal Article     Date:  2009-12-02
Journal Detail:
Title:  Journal of electrocardiology     Volume:  43     ISSN:  1532-8430     ISO Abbreviation:  J Electrocardiol     Publication Date:    2010 Mar-Apr
Date Detail:
Created Date:  2010-02-17     Completed Date:  2010-05-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  161-6     Citation Subset:  IM    
Copyright Information:
2010 Elsevier Inc. All rights reserved.
The Aga Khan University Hospital, Karachi, Pakistan.
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MeSH Terms
Diagnosis, Computer-Assisted / methods*
Electrocardiography / methods*
Heart Septal Defects, Atrial / complications*,  diagnosis*
Hypertrophy, Right Ventricular / complications*,  diagnosis*
Middle Aged
Reproducibility of Results
Sensitivity and Specificity
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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