| The utility of megavoltage computed tomography images from a helical tomotherapy system for setup verification purposes. | |
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MedLine Citation:
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PMID: 15590196 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To evaluate the utility of relatively low-dose megavoltage computed tomography (MVCT) images from a clinical helical tomotherapy system for setup verification purposes. METHODS AND MATERIALS: Cross-sectional kilovolt computed tomography (kVCT) images were obtained for treatment planning purposes on a diagnostic third-generation CT scanner, followed by MVCT images from a helical tomotherapy system in 8 pet dogs with spontaneously occurring tumors. The kVCT and MVCT images were aligned for setup verification purposes, allowing repositioning before treatment delivery. RESULTS: Tumors are readily visualized on the MVCT images. At a dose of 2-3 cGy, the MVCT images are of sufficient quality for verification of treatment setup, but soft-tissue contrast is inferior to that with conventional kVCT. The MV and kVCT images were successfully aligned. When necessary, patients undergoing helical tomotherapy were repositioned before treatment. CONCLUSIONS: Megavoltage CT image quality is sufficient for tumor identification and three-dimensional setup verification in dogs with spontaneous tumors. The MVCT images can be aligned with the planning kVCT to ensure proper patient registration before treatment. Image alignment was successful in these canine patients, despite no skin markings defining patient positioning between the two scans. MVCT images facilitate setup verification, and their tomographic nature offers improvements over conventional portal imaging. |
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Authors:
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Lisa J Forrest; Thomas Rockwell Mackie; Ken Ruchala; Michelle Turek; Jeff Kapatoes; Hazim Jaradat; Susanta Hui; John Balog; David M Vail; Minesh P Mehta |
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Publication Detail:
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Type: Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: International journal of radiation oncology, biology, physics Volume: 60 ISSN: 0360-3016 ISO Abbreviation: Int. J. Radiat. Oncol. Biol. Phys. Publication Date: 2004 Dec |
Date Detail:
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Created Date: 2004-12-13 Completed Date: 2005-01-10 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7603616 Medline TA: Int J Radiat Oncol Biol Phys Country: United States |
Other Details:
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Languages: eng Pagination: 1639-44 Citation Subset: IM |
Affiliation:
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Department of Human Oncology, University of Wisconsin, Madison, WI, USA. forrestl@svm.vetmed.wisc.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bone Neoplasms / radiotherapy*, veterinary Calibration Dog Diseases / radiotherapy Dogs Nasopharyngeal Neoplasms / radiotherapy*, veterinary Osteosarcoma / radiotherapy*, veterinary Radiotherapy Planning, Computer-Assisted / instrumentation, methods* Radiotherapy, Conformal / instrumentation, methods* Tomography, Spiral Computed / instrumentation, methods* |
| Grant Support | |
ID/Acronym/Agency:
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P01 CA088960/CA/NCI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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