Document Detail

The utility of embryo banking in order to increase the number of embryos available for preimplantation genetic screening in advanced maternal age patients.
MedLine Citation:
PMID:  20811806     Owner:  NLM     Status:  MEDLINE    
PURPOSE: to determine if embryo banking with PGS is more optimal than proceeding with PGS regardless of embryo number.
METHODS: patients were divided into 2 groups, group 1 were those that banked embryos and proceeded through another round of IVF prior to PGS, and group 2 underwent PGS regardless of embryo number. Group 2 was divided into group 2A (patients with >10 embryos) and group 2B (patients who had <10 embryos).
RESULTS: there was no difference in embryos biopsied, normal embryos, number transferred, and pregnancy rate between group 1 and 2. A significant number of patients did not have a transfer in group 2B (6/11) compared to group 1 (3/19) (P = 0.0419). There was no significance between pregnancy rates per transfer between group 1 (6/16) and group 2B (2/5).
CONCLUSION: our data suggests that banking will increase the odds of going to transfer but there was no increase in pregnancy rates.
John J Orris; Tyl H Taylor; Janice W Gilchrist; Susan V Hallowell; Michael J Glassner; J David Wininger
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2010-09-02
Journal Detail:
Title:  Journal of assisted reproduction and genetics     Volume:  27     ISSN:  1573-7330     ISO Abbreviation:  J. Assist. Reprod. Genet.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-07     Completed Date:  2011-03-24     Revised Date:  2013-05-28    
Medline Journal Info:
Nlm Unique ID:  9206495     Medline TA:  J Assist Reprod Genet     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  729-33     Citation Subset:  IM    
Main Line Fertility and Reproductive Medicine, IVF Lab, 130 S. Bryn Mawr Ave., Ground Floor, D Wing, Bryn Mawr, PA 19010, USA.
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MeSH Terms
Embryo Transfer*
Fertilization in Vitro
Genetic Testing*
Maternal Age*
Pregnancy Rate*
Preimplantation Diagnosis / methods*
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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