Document Detail


The utility of conditioning sequences in barostat protocols for the measurement of rectal compliance.
MedLine Citation:
PMID:  23320603     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
INTRODUCTION: The barostat can be used to measure rectal sensitivity, compliance and elastance all of which are potentially important physiological parameters in the pathophysiology of faecal incontinence. Current practice recommends a conditioning distension sequence be performed prior to index distensions. We questioned the validity of this by comparing values for rectal compliance during sequential conditioning (CD) and index (ID) distensions in physiologically normal subjects. METHODS: 10 subjects (5 male, mean age 55.2 years)with normal anal canal manometry, anorectal sensitivity and balloon distension thresholds were studied. After determining the minimum distension pressure, subjects underwent sequential isobaric distensions: CD 4mmHg distensions every 45 seconds and ID 4mmHg every 2 minutes, both to a maximum of 24mmmHg or patient tolerance. Compliance values from both sequences were calculated by measuring the maximum slope of pressure-volume curves. A paired t test was performed to compare any differences between sequences. RESULTS: Mean rectal compliance were 11.4ml/mmHG (SD 5.8ml/mmHG) and 10.9ml/mmHg (SD 5.7ml/mmHg) in the CD and ID respectively with no statistical difference noted between distensions (p=0.78). CONCLUSIONS: Rectal compliance can be measured with a single distension protocol without the need for an initial conditioning distension. Conditioning the rectum adds additional complexity to barostat protocols and is not necessary. © 2013 The Authors. Colorectal Disease © 2013 The Association of Coloproctology of Great Britain and Ireland.
Authors:
A Bajwa; K Thiruppathy; A Emmanuel
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-15
Journal Detail:
Title:  Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland     Volume:  -     ISSN:  1463-1318     ISO Abbreviation:  Colorectal Dis     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883611     Medline TA:  Colorectal Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2013 The Authors. Colorectal Disease © 2013 The Association of Coloproctology of Great Britain and Ireland.
Affiliation:
University College Hospital, Department of Gastroenterology and Nutrition, London, United Kingdom.
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