| The utility of cardiopulmonary exercise testing to detect and track early-stage ischemic heart disease. | |
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MedLine Citation:
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PMID: 20884826 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Evidence demonstrating the potential value of noninvasive cardiopulmonary exercise testing (CPET) to accurately detect exercise-induced myocardial ischemia is emerging. This case-based concept report describes CPET abnormalities in an asymptomatic at-risk man with suspected early-stage ischemic heart disease. When CPET was repeated 1 year after baseline assessment, his cardiovascular function had worsened, and an anti-atherosclerotic regimen was initiated. When the patient was retested after 3.3 years, the diminished left ventricular function had reversed with pharmacotherapy directed at decreasing cardiovascular events in patients with coronary artery disease. Thus, in addition to identifying appropriate patients in need of escalating therapy for atherosclerosis, CPET was useful in monitoring progression and reversal of abnormalities of the coronary circulation in a safe and cost-effective manner without the use of radiation. Serial CPET parameters may be useful to track changes marking the progression and/or regression of the underlying global ischemic burden. |
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Authors:
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Sundeep Chaudhry; Ross A Arena; James E Hansen; Gregory D Lewis; Jonathan N Myers; Laurence S Sperling; Brian D Labudde; Karlman Wasserman |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Mayo Clinic proceedings. Mayo Clinic Volume: 85 ISSN: 1942-5546 ISO Abbreviation: Mayo Clin. Proc. Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-04 Completed Date: 2010-10-26 Revised Date: 2010-11-09 |
Medline Journal Info:
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Nlm Unique ID: 0405543 Medline TA: Mayo Clin Proc Country: United States |
Other Details:
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Languages: eng Pagination: 928-32 Citation Subset: AIM; IM |
Affiliation:
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Research and Development Department, MET-TEST, Atlanta, GA, USA. schaudhry@mettest.net |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anaerobic Threshold / physiology* Cholesterol, LDL / blood Disease Progression Exercise Test / methods, utilization* Follow-Up Studies Heart Rate Humans Male Myocardial Ischemia / blood, diagnosis*, physiopathology Oxygen Consumption / physiology Reproducibility of Results |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, LDL |
| Comments/Corrections | |
Erratum In:
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Mayo Clin Proc. 2010 Nov;85(11):1061 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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