Document Detail


The uterus and fertility.
MedLine Citation:
PMID:  18155200     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To review the current understanding of the role the uterus plays in embryo implantation and to outline congenital anomalies and acquired diseases that impact normal uterine function. DESIGN: The publications related to the embryo implantation, Mullerian anomalies, uterine polyps, uterine synechiae, and myomas were identified through Medline and reviewed. CONCLUSION(S): Congenital anomalies and acquired diseases of the uterus may negatively impact on the complex processes of embryo implantation. Hysteroscopic surgery to correct uterine septa, intrauterine synechiae, and myomas that distort the uterine cavity may benefit women with infertility or recurrent pregnancy loss. The effect of endometrial polyps on fertility is uncertain, but their removal, once identified, is justifiable. Complex congenital anomalies such as unicornuate uterus and uterus didelphys may negatively affect fertility and pregnancy outcome, and surgical treatment may benefit select patients.
Authors:
Elizabeth Taylor; Victor Gomel
Publication Detail:
Type:  Journal Article; Review     Date:  2007-12-21
Journal Detail:
Title:  Fertility and sterility     Volume:  89     ISSN:  1556-5653     ISO Abbreviation:  Fertil. Steril.     Publication Date:  2008 Jan 
Date Detail:
Created Date:  2008-01-14     Completed Date:  2008-01-24     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0372772     Medline TA:  Fertil Steril     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1-16     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University of British Columbia, BC Women's Hospital and Women's Health Centre,Vancouver, British Columbia, Canada. victorgomel@cs.com
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MeSH Terms
Descriptor/Qualifier:
Embryo Implantation*
Endometrial Neoplasms / complications,  physiopathology
Female
Fertility*
Gynecologic Surgical Procedures
Humans
Infertility, Female / etiology*,  physiopathology,  surgery
Leiomyoma / complications,  physiopathology
Mullerian Ducts / abnormalities,  physiopathology
Polyps / complications,  physiopathology
Pregnancy
Pregnancy Outcome
Tissue Adhesions / complications,  physiopathology
Treatment Outcome
Uterine Diseases / complications,  physiopathology
Uterine Neoplasms / complications,  physiopathology
Uterus / abnormalities,  physiopathology*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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