| The usefulness of dietary medium-chain triglycerides in body weight control: fact or fancy? | |
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MedLine Citation:
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PMID: 8732772 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Compared to long-chain triglycerides (LCT), medium-chain triglycerides (MCT) display some specific physico-chemical, and biological characteristics. Thus, MCT are currently used in clinical nutrition as energy-yielding substrates, and have been advocated for three decades as a useful mean for body weight reduction. This review encompasses most aspects of MCT metabolism arguing this slimming hypothesis pro and con. Findings in support of the opinion (lower energy density, control of satiety, rapid intrahepatic delivery and oxidation rates, poor adipose tissue incorporation) may be invalidated by counteracting data (stimulation of insulin secretion and of anabolic-related processes, increased de novo fatty acid synthesis, induced hypertriglyceridemia). The balance between these two opposing influences depends on the composition (energy intake, nature of ingredients, MCT/LCT ratio, octanoate/decanoate ratio) and duration of the regimen. Due to the high energy level (around 50%) of MCT necessary to achieve body weight loss, long-term compliance to such slimming regimens is unlikely in human nutrition. |
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Authors:
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A C Bach; Y Ingenbleek; A Frey |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of lipid research Volume: 37 ISSN: 0022-2275 ISO Abbreviation: J. Lipid Res. Publication Date: 1996 Apr |
Date Detail:
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Created Date: 1997-01-30 Completed Date: 1997-01-30 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0376606 Medline TA: J Lipid Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 708-26 Citation Subset: IM |
Affiliation:
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CEPE, CNRS, Strasbourg, France. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adipose Tissue
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anatomy & histology,
drug effects Animals Body Weight / drug effects Dietary Fats / administration & dosage*, pharmacokinetics Energy Intake Energy Metabolism Fatty Acids / metabolism Humans Lipid Metabolism Lipids / blood Liver / metabolism Obesity / diet therapy*, metabolism Tissue Distribution Triglycerides / administration & dosage*, chemistry, pharmacokinetics Weight Loss / drug effects*, physiology |
| Chemical | |
Reg. No./Substance:
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0/Dietary Fats; 0/Fatty Acids; 0/Lipids; 0/Triglycerides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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