Document Detail

The use of transcranial Doppler pulsatility index to guide hyperosmolar therapy.
MedLine Citation:
PMID:  23022902     Owner:  NLM     Status:  In-Data-Review    
Management of intracranial hypertension is a major cornerstone of neurocritical care. Apart from traumatic brain injury, there are no clear guidelines for intracranial pressure (ICP) monitoring. The insertion of ICP monitors is an invasive procedure with inherent risks and could be contraindicated in case of severe coagulopathy. The transcranial Doppler (TCD) pulsatility index (PI) has emerged as a surrogate marker for ICP. This is a technical report with illustrative cases on the use of PI in the management of high ICP, as a guide for optimal dosing of hyperosmolar agents we use in our institution. The use of TCD PI is a useful adjunct to guide the use of hyperosmolar therapy in various conditions with raised intracranial hypertension. We will discuss the combination of the PI determination with an anatomical evaluation of the optic nerve diameter to eliminate confounding factors in PI determination.
Hosam M Al-Jehani; Judith Marcoux; Mark R Angle; Jeanne S Teitelbaum
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurosciences (Riyadh, Saudi Arabia)     Volume:  17     ISSN:  1319-6138     ISO Abbreviation:  Neurosciences (Riyadh)     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101252453     Medline TA:  Neurosciences (Riyadh)     Country:  Saudi Arabia    
Other Details:
Languages:  eng     Pagination:  363-7     Citation Subset:  IM    
c/o A. Sabbagh, National Neurosciences Institute (020007), King Fahd Medical City, PO Box 59046, Riyadh 11525, Kingdom of Saudi Arabia. Tel. +966 (1) 2889999 Ext. 8211/2305 Fax. +966 (1) 2889999 Ext. 1391. E-mail:
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